Holdings: Cancer chemotherapy

Cancer chemotherapy: [basic science to the clinic]

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Bibliographic Details
Main Author:	Airley, Rachel (Author)
Format:	Book
Language:	English
Published:	Chichester [u.a.] Wiley-Blackwell 2009
Edition:	1st publ.
Subjects:	Cytostatikum Krebs > Medizin Chemotherapie
Online Access:	Inhaltsverzeichnis Inhaltsverzeichnis
Item Description:	Literaturverz. S. [299]-330
Physical Description:	X, 341 S. Ill., graph. Darst.
ISBN:	9780470092545 9780470092552

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MARC


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adam_text	IMAGE 1 PREFACE P. IX CANCER EPIDEMIOLOGY P. 1 CANCER INCIDENCE, PREVALENCE AND MORTALITY P. 1 CHILDHOOD CANCERS P. 3 GLOBAL EPIDEMIOLOGY P. 6 HISTOPATHOLOGY OF CANCER P. 11 INTRODUCTION P. 11 MALIGNANT, BENIGN AND NORMAL (NON-MALIGNANT) TISSUE P. 11 CELL DEATH P. 12 CARCINOGENESIS, MALIGNANT TRANSFORMATION AND PROGRESSION P. 19 INTRODUCTION P. 19 CHEMICAL CARCINOGENESIS P. 19 MOLECULAR BIOLOGY OF CANCER: ONCOGENES AND TUMOUR SUPPRESSOR GENES P. 23 INTRODUCTION P. 23 ONCOGENESIS P. 25 TUMOUR SUPPRESSOR GENES P. 30 TUMOUR METASTASIS: A CONVERGENCE OF MANY THEORIES P. 37 INTRODUCTION P. 37 DETACHMENT AND MIGRATION FROM THE PRIMARY TUMOUR P. 37 INTRAVASATION P. 38 TRANSPORT P. 42 EXTRAVASATION P. 43 GROWTH OF THE METASTATIC TUMOUR MASS P. 45 HEALTH PROFESSIONALS IN THE TREATMENT OF CANCER P. 49 INTRODUCTION P. 49 PATHOLOGY P. 49 RADIOLOGY P. 50 ROLE OF THE SURGICAL ONCOLOGIST P. 51 ONCOLOGY PHARMACY P. 52 ONCOLOGY NURSING P. 53 THE NHS CANCER PLAN P. 54 PRINCIPLES OF CANCER CHEMOTHERAPY P. 55 INTRODUCTION P. 55 TIMING OF CHEMOTHERAPY P. 55 BIOMARKERS AND THEIR USES P. 59 CLINICAL ASSESSMENT OF BIOMARKERS P. 59 PHARMACOGENETICS AND PHARMACOGENOMICS OF CANCER CHEMOTHERAPY P. 64 CLASSICAL ANTICANCER AGENTS P. 67 INTRODUCTION P. 67 ALKYLATING AGENTS P. 67 ANTIMETABOLITES P. 71 IMAGE 2 AGENTS DERIVED FROM NATURAL OR SEMISYNTHETIC PRODUCTS P. 77 HORMONAL ANTICANCER AGENTS P. 106 CLINICALLY USED CHEMOTHERAPY REGIMENS P. 111 THE PHILOSOPHY OF CANCER RESEARCH P. 117 INTRODUCTION P. 117 STRUCTURE OF CANCER RESEARCH ORGANIZATIONS IN THE UNITED KINGDOM P. 118 CANCER RESEARCH IN THE UNITED STATES P. 120 NOVEL ANTICANCER AGENTS P. 125 INTRODUCTION P. 125 TARGET VALIDATION P. 125 IDENTIFICATION AND OPTIMIZATION OF LEAD DRUGS P. 146 PRECLINICAL PHARMACOLOGY P. 148 CLINICAL TRIALS P. 167 INTRODUCTION P. 167 EVALUATION OF TREATMENT RESPONSE P. 169 ASSESSMENT OF VASCULARITY AND ANGIOGENESIS BY NUCLEAR MEDICINE TECHNOLOGY P. 173 TUMOUR HYPOXIA P. 177 INTRODUCTION P. 177 BIOREDUCTIVE DRUGS P. 181 INHIBITORS OF HIF-1 AND HIF-1-REGULATED GENES P. 187 ANTIANGIOGENIC AND ANTIVASCULAR AGENTS P. 199 HISTORY OF ANGIOGENESIS AS A THERAPEUTIC TARGET P. 199 ANTI-ANGIOGENIC DRUG TARGETS P. 202 THE RETURN OF THALIDOMIDE P. 209 MONOCLONAL ANTIBODIES AS ANTI-ANGIOGENIC AGENTS P. 212 THE HOLLOW FIBRE ASSAY AS A DRUG SCREEN FOR ANTI-ANGIOGENIC DRUGS P. 213 VASCULAR DISRUPTING AGENTS P. 215 TYROSINE KINASE INHIBITORS P. 217 INTRODUCTION P. 217 TYROSINE KINASE INHIBITORS TARGETING ANGIOGENESIS P. 219 NON-RECEPTOR TYROSINE KINASE INHIBITORS P. 221 RAS INHIBITORS P. 225 INHIBITORS OF THE AKT/PKB PATHWAY P. 229 TARGETING STRESS PROTEINS: HSP90 INHIBITORS P. 233 THE PROTEASOME P. 237 INTRODUCTION P. 237 THE PROTEASOME AS A TARGET FOR NOVEL DRUG STRATEGIES P. 239 UBIQUITYLATION AS A TARGET P. 240 CHECKPOINT PROTEIN KINASES AS NOVEL TARGETS - MAMMALIAN TARGET OF RAPAMYCIN (MTOR) P. 245 MAMMALIAN TARGET OF RAPAMYCIN P. 245 STRUCTURE AND ACTIVATION OF MTOR P. 246 IMAGE 3 NOVEL ANTICANCER AGENTS TARGETING MTOR P. 248 TELOMERASE P. 249 HISTONE DEACETYLASE: AN EPIGENETIC DRUG TARGET P. 255 INTRODUCTION P. 255 HDAC AND DNA PACKAGING P. 255 HDAC INHIBITORS P. 261 PHARMACEUTICAL PROBLEMS IN CANCER CHEMOTHERAPY P. 265 MANIFESTATION OF TOXICITY P. 265 REGIMEN-RELATED TOXICITY P. 269 SECONDARY MALIGNANCIES P. 270 DRUG RESISTANCE P. 271 PHARMACEUTICAL COMPLICATIONS P. 274 PHLEBITIS AND VENOUS IRRITATION P. 279 HEALTH AND SAFETY P. 279 NATIONAL GUIDANCE ON THE SAFE ADMINISTRATION OF INTRATHECAL CHEMOTHERAPY P. 279 ONCOLOGY PHARMACY AT HOME AND ABROAD P. 281 PRACTICE EXAM QUESTIONS P. 283 BIBLIOGRAPHY AND FURTHER READING P. 299 INDEX P. 331 TABLE OF CONTENTS PROVIDED BY BLACKWELL'S BOOK SERVICES AND R.R. BOWKER. USED WITH PERMISSION.
any_adam_object	1
author	Airley, Rachel
author_facet	Airley, Rachel
author_role	aut
author_sort	Airley, Rachel
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building	Verbundindex
bvnumber	BV025603584
classification_rvk	VS 9100 XI 7000
ctrlnum	(OCoLC)637560407 (DE-599)BVBBV025603584
dewey-full	616.994061
dewey-hundreds	600 - Technology (Applied sciences)
dewey-ones	616 - Diseases
dewey-raw	616.994061
dewey-search	616.994061
dewey-sort	3616.994061
dewey-tens	610 - Medicine and health
discipline	Chemie / Pharmazie Medizin
edition	1st publ.
format	Book
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language	English
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spelling	Airley, Rachel Verfasser aut Cancer chemotherapy [basic science to the clinic] Rachel Airley 1st publ. Chichester [u.a.] Wiley-Blackwell 2009 X, 341 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Literaturverz. S. [299]-330 Cytostatikum (DE-588)4068347-3 gnd rswk-swf Krebs Medizin (DE-588)4073781-0 gnd rswk-swf Chemotherapie (DE-588)4127083-6 gnd rswk-swf Krebs Medizin (DE-588)4073781-0 s Chemotherapie (DE-588)4127083-6 s Cytostatikum (DE-588)4068347-3 s DE-604 DE-601 pdf/application http://www.gbv.de/dms/bowker/toc/9780470092552.pdf Inhaltsverzeichnis GBV Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=020198773&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis
spellingShingle	Airley, Rachel Cancer chemotherapy [basic science to the clinic] Cytostatikum (DE-588)4068347-3 gnd Krebs Medizin (DE-588)4073781-0 gnd Chemotherapie (DE-588)4127083-6 gnd
subject_GND	(DE-588)4068347-3 (DE-588)4073781-0 (DE-588)4127083-6
title	Cancer chemotherapy [basic science to the clinic]
title_auth	Cancer chemotherapy [basic science to the clinic]
title_exact_search	Cancer chemotherapy [basic science to the clinic]
title_full	Cancer chemotherapy [basic science to the clinic] Rachel Airley
title_fullStr	Cancer chemotherapy [basic science to the clinic] Rachel Airley
title_full_unstemmed	Cancer chemotherapy [basic science to the clinic] Rachel Airley
title_short	Cancer chemotherapy
title_sort	cancer chemotherapy basic science to the clinic
title_sub	[basic science to the clinic]
topic	Cytostatikum (DE-588)4068347-3 gnd Krebs Medizin (DE-588)4073781-0 gnd Chemotherapie (DE-588)4127083-6 gnd
topic_facet	Cytostatikum Krebs Medizin Chemotherapie
url	http://www.gbv.de/dms/bowker/toc/9780470092552.pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=020198773&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA
work_keys_str_mv	AT airleyrachel cancerchemotherapybasicsciencetotheclinic

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