Monitoring stem cell research:
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
Washington, D.C.
Bioethics
2004
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| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | XIX, 414 Seiten |
Internformat
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Datensatz im Suchindex
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| adam_text | V CONTENTS LETTER OF TRANSMITTAL TO THE PRESIDENT MEMBERS OF THE
PRESIDENT S COUNCIL ON BIOETHICS COUNCIL STAFF AND CONSULTANTS PREFACE 1
INTRODUCTION I. WHAT ARE STEM CELLS, AND WHY IS THERE CONTENTION ABOUT
THEM? 2 II. BROADER ETHICAL ISSUES 5 III. TYPES OF STEM CELLS: AN
INTRODUCTION 8 A. EMBRYONIC STEM (ES) CELLS 8 B. EMBRYONIC GERM (EG)
CELLS 9 C. ADULT (OR NON-EMBRYONIC) STEM CELLS 10 D. CORD BLOOD STEM
CELLS 11 IV. TERMINOLOGY 12 V. ABOUT THE REPORT 15 ENDNOTES 20 XM XV
XV11 2 CURRENT FEDERAL LAW AND POLICY I. A BRIEF HISTORY OF THE EMBRYO
RESEARCH FUNDING DEBATE 22 II. THE PRESENT POLICY 28 III. MORAL
FOUNDATION OF THE POLICY 30 IV. THE SIGNIFICANCE OF FEDERAL FUNDING 37
V. IMPLEMENTATION OF THE PRESENT POLICY 41 VI. CONCLUSION 47 ENDNOTES 49
21 VI CONTENTS 3 RECENT DEVELOPMENTS IN THE ETHICAL AND POLICY DEBATES
53 I. THE NATURE OF THE MORAL ARGUMENT 54 II. THE MORAL AIMS OF POLICY
58 A. THE IMPORTANCE OF RELIEVING SUFFERING 58 B. FREEDOM TO CONDUCT
RESEARCH 61 C. THE MORAL STANDING OF HUMAN EMBRYOS 62 III. THE CHARACTER
OF THE POLICY 63 A. ARBITRARY 63 B. UNSUSTAINABLE 65 C. INCONSISTENT 67
IV. THE MORAL STANDING OF HUMAN EMBRYOS 74 A. CONTINUITY AND
DISCONTINUITY 76 1. THE CASE FOR CONTINUITY. 76 2. THE CASE FOR
MEANINGFUL DISCONTINUITY AND DEVELOPING MORAL STATUS. 78 B. SPECIAL
CASES AND EXCEPTIONS 84 1. IVF SPARES. 84 2. NATURAL EMBRYO LOSS. 88
3. PREDICTION OF NON-VIABILITY OF EMBRYOS. 89 4. CREATION OF NON-VIABLE
EMBRYO-LIKE ARTIFACTS. 90 V. SOCIETAL SIGNIFICANCE AND PUBLIC
RESPONSIBILITY 93 VI. CONCLUSION 97 ENDNOTES 98 4 RECENT DEVELOPMENTS IN
STEM CELL RESEARCH AND THERAPY 109 I. STEM CELLS AND THEIR DERIVATIVES
111 II. REPRODUCIBLE RESULTS USING STEM CELL PREPARATIONS AND THEIR
DERIVATIVES 116 A. INITIAL STEM CELL PREPARATIONS CAN CONTAIN MULTIPLE
CELL TYPES 116 B. GENETICALLY HOMOGENEOUS STEM CELLS THROUGH SINGLE CELL
CLONING 117 C. EXPANSION IN VITRO, PRESERVATION, AND STORAGE 118 D.
CHROMOSOME CHANGES 119 CONTENTS VII E, DEVELOPMENTAL HETEROGENEITY OF
STEM CELL PREPARATIONS 119 F. MICROBIAL CONTAMINATION 120 III. MAJOR
EXAMPLES OF HUMAN STEM CELLS 121 A. HUMAN ADULT STEM CELLS 122 1. HUMAN
MESENCHYMAL STEM CELLS. 122 2. MULTIPOTENT ADULT PROGENITOR CELLS
(MAPCS). 123 3. HUMAN NEURAL STEM CELLS. 124 4. ADULT STEM CELLS FROM
OTHER SOURCES. 125 B. HUMAN EMBRYONIC STEM CELLS 126 1. HUMAN EMBRYONIC
STEM CELLS (ESCS) . 126 2. EMBRYONIC GERM CELLS. 127 3. EMBRYONIC STEM
CELLS FROM CLONED EMBRYOS (CLONED ESCS). 128 IV. BASIC RESEARCH USING
HUMAN STEM CELLS 129 V. HUMAN STEM CELLS AND THE TREATMENT OF DISEASE
131 A. WILL STEM CELL-BASED THERAPIES BE LIMITED BY IMMUNE REJECTION?
131 B. CASE STUDY: STEM CELLS IN THE FUTURE TREATMENT OF TYPE-1
DIABETES? 133 1. THE DISEASE AND ITS CAUSES. 133 2. CURRENT THERAPY
CHOICES AND OUTCOMES. 134 3. STEM CELL THERAPY FOR TYPE-1 DIABETES? 135
C. THERAPEUTIC APPLICATIONS OF MESENCHYMAL STEM CELLS (MSCS) 137 D.
EVALUATING THE DIFFERENT TYPES OF STEM CELLS 138 VI. PRIVATE SECTOR
ACTIVITY 138 * VII. PRELIMINARY CONCLUSIONS 139 ENDNOTES 141 GLOSSARY OF
TERMS 147 APPENDIX A. NOTES ON EARLY HUMAN DEVELOPMENT 157 STAFF OF THE
PRESIDENT S COUNCIL ON BIOETHICS APPENDLX B. REMARKS BY THE PRESIDENT ON
STEM CELL RESEARCH, AUGUST 9, 2001 183 PRESIDENT GEORGE W. BUSH APPENDLX
C. BUSH ADMINISTRATION NIH GUIDELINES FOR EMBRYONIC STEM CELL FUNDING
189 VLLL CONTENTS APPENDIX D. CLINTON ADMINISTRATION GUIDELINES FOR
EMBRYONIC STEM CELL FUNDING 191 COMMISSIONED APPENDIX E. PAPERS 198
APPENDIX F. APPENDIX G. APPENDIX H, APPENDIX I. APPENDIX J. APPENDIX K.
APPENDIX L. APPENDIX M. APPENDIX N. LEGISLATORS AS LOBBYISTS: PROPOSED
STATE REGULATION OF EMBRYONIC STEM CELL RESEARCH, THERAPEUTIC CLONING
AND REPRODUCTIVE CLONING 199 LORI B. ANDREWS, J.D. THE MEANING OF
FEDERAL FUNDING PETER BERKOWITZ, J.D., PH.D. 225 REPORT ON THE ETHICS OF
STEM CELL RESEARCH PAUL LAURITZEN, PH.D. 237 HUMAN EMBRYONIC GERM CELLS:
JUNE 2001-JULY 2003, THE PUBLISHED RECORD 273 JOHN GEARHART, PH.D.
CURRENT PROGRESS IN HUMAN EMBRYONIC STEM CELL RESEARCH 279 TENNEILLE E.
LUDWIG, PH.D., AND JAMES A. THOMSON, PH.D. MULTIPOTENT ADULT PROGENITOR
CELLS: AN UPDATE 295 CATHERINE M. VERFAILLIE, M.D. ADULT STEM CELLS 309
DAVID A. PRENTICE, PH.D. STEM CELLS AND TISSUE REGENERATION: LESSONS
FROM RECIPIENTS OF SOLID ORGAN TRANSPLANTATION 347 SILVIU ITESCU, M.D.
POTENTIAL USE OF CELLULAR THERAPY FOR PATIENTS WITH HEART DISEASE 365
SILVIU ITESCU, M.D. THE BIOLOGY OF NUCLEAR CLONING AND THE POTENTIAL OF
EMBRYONIC STEM CELLS FOR TRANSPLANTATION THERAPY 385 RUDOLF JAENISCH,
M.D.
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| spelling | Monitoring stem cell research report of the President's Council on Bioethics Washington, D.C. Bioethics 2004 XIX, 414 Seiten txt rdacontent n rdamedia nc rdacarrier Forschung (DE-588)4017894-8 gnd rswk-swf Stammzelle (DE-588)4665329-6 gnd rswk-swf Bioethik (DE-588)4006791-9 gnd rswk-swf USA (DE-588)4078704-7 gnd rswk-swf USA (DE-588)4078704-7 g Stammzelle (DE-588)4665329-6 s Forschung (DE-588)4017894-8 s Bioethik (DE-588)4006791-9 s DE-604 USA Council on Bioethics Sonstige (DE-588)3056471-2 oth SWB Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=019986764&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
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| subject_GND | (DE-588)4017894-8 (DE-588)4665329-6 (DE-588)4006791-9 (DE-588)4078704-7 |
| title | Monitoring stem cell research |
| title_auth | Monitoring stem cell research |
| title_exact_search | Monitoring stem cell research |
| title_full | Monitoring stem cell research report of the President's Council on Bioethics |
| title_fullStr | Monitoring stem cell research report of the President's Council on Bioethics |
| title_full_unstemmed | Monitoring stem cell research report of the President's Council on Bioethics |
| title_short | Monitoring stem cell research |
| title_sort | monitoring stem cell research |
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