Molecular diagnostics: techniques and applications for the clinical laboratory
Gespeichert in:
Format: | Buch |
---|---|
Sprache: | English |
Veröffentlicht: |
Amsterdam [u.a.]
Elsevier, Acad. Press
2010
|
Schlagworte: | |
Online-Zugang: | Inhaltsverzeichnis Klappentext |
Beschreibung: | IX, 484 S. Ill., graph. Darst. |
ISBN: | 9780123694287 0123694280 |
Internformat
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Datensatz im Suchindex
_version_ | 1809493932191514624 |
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adam_text |
Contents
Forword ix
1. Quantitative PCR: An
Introduction
3
Marilynn R., Fairfax and Hossein Salimnia
2. Signal
Amplification
Methods in
Molecular Diagnostics
15
Maura Pieretti
3.
The Lab-on-a-Chip Approach for
Molecular
Diagnostics
21
Xiaole
Мао,
Tony
Jun
Huang
and
Chih-Ming
Но
4.
Nucleic Extraction and
Amplification
35
Weimin Sun
5.
General Procedures
49
Weimin Sun
6.
Next-Generation Sequencing in
Molecular Diagnostics
59
John R. ten Bosch and Wayne
W. Grody
7.
In Situ Hybridization: Principles and
Applications
71
Elizabeth R.
Unger,
Hiroaki Nitta, Daisy R. Lee and
Thomas M. Grogan
8.
Billing and Reimbursement for
Molecular Diagnostics
83
Michael S. Watson and
Michele
Schoonmaker
9.
Molecular Pathology and Infectious
Diseases
99
Frederick
L Kiechle
10.
Ethical Considerations in Molecular
Diagnostics
107
Mary Kay Pelias and Robert M. Fineman
11.
Quality Control, Assurance,
Identification, and Standards
115
MatthewJ. McGinniss
12.
Regulatory Issues in Molecular
Diagnostics
121
Wayne
W. Grody
13.
Thrombophilia
127
Mervyn A. Sahud and Dr. Charles Strom
14.
Molecular Testing for Cystic
Fibrosis and CFTK-Related
Conditions
149
Barbara A. Karczeski and Garry R. Cutting
15.
Molecular Genetic Testing for
Х
-linked Mental Retardation
Disorders
167
Benjamin
Roa
and Joanna Wiszniewska
16.
Hemochromatosis
177
Ernest Beutler and Pauline Lee
17.
Standards and Recommendations
for Molecular Diagnostic Testing for
Huntington
Disease, the Autosomal
Dominant Spinocerebellar
Ataxias,
and
Friedreich
Ataxia
191
Nicholas
T.
Potter
18.
The Role of Micro-RNAs in Cancer
205
Y
Kasahara, R.M. Nakamura and
P.S.
Kim
19.
Molecular Diagnostics in the Evaluation
of Cancer: Modern Concepts and
Overview
215
R.M. Nakamura and Y. Kasahara
20.
Gene Expression Analysis for Tumor
Profiling
225
Richard A. Bender, Kevin Qu and Steven J. Potts
21.
Molecular Diagnostics of Hematopoietic
Disorders
243
Jason D.
Merker
and Daniel A. Arber
vu
(Ж)
Contents
Viruses
22.
Molecular Diagnostics for the
Hepatitis
С
Virus
263
Carol A. Holland and Thomas M.
Přibyl
23.
Molecular Diagnosis of
Cytomegalovirus
277
Rodney
G
Arcenas
24.
Molecular Detection of Multiple
Respiratory Viruses
289
Jeanne Can, Donna G. Williams and
Randall T. Hayden
25.
Human Papillomavirus and its Role in
Cervical Carcinoma
301
Qinghua Feng, Mingjun Jiang, Georgios
Deňereos
and Nancy B. Kiviat
Bacteria
26.
Molecular Methods for
Identification and Characterization of
Acinetobacter spp.
313
D. Jane
Hata
27.
Molecular Detection and Surveillance
of Healthcare-Associated
Infections
327
Arundhati Rao, Bob Fader and Kimberly
Hocker
28.
Molecular Detection of Group
В
Streptococcus
341
Jane S. Gibson
29.
Role of Molecular Techniques in the
Epidemiologie
Investigation of
Hospital-Acquired Infections
351
Katherine
Reyes and Marcus Zervos
30.
Molecular
HLA
Typing Methods Used in
Clinical Laboratories
367
Raja Rajalingam, Michael
Cecka
and
Elaine F. Reed
31.
Identification Through
DNA
Analysis
in Criminal and Family-Relatedness
Investigations
381
Robert W.Allen
32.
Overview of Pharmacogenomics and
Applications for the Modern Clinical
Laboratory
401
E. Scott Seeley, Run Zhang Shi and
Paul Jannetto
33.
UDP-Glucuronosyltransferase
1A1 and the Glucuronidation
in Oncology Applications and
Hyperbilirubinemia
409
Jennifer M. Skierka and Dennis J. O'Kane
34.
Pharmacogenetics of Cytochrome P450
Enzymes
421
Paul J. Jannetto
35.
Pharmacogenomics of Thiopurine
Methyl
Transferase (TPMT):
Importance
in Monitoring of Mercaptopurine/
Azathioprine Therapy
433
R.M. Nakamura, M. Barry and M. Matsutani
36.
Molecular Diagnostic Challenges of the
Thalassemias
441
Farid F. Chehab
37.
Herpes Simplex Virus
453
Danny
L
Wiedbrauk
38.
Molecular Diagnostic Evaluation of
Deaf and Hard-of-Hearing
Individuals
461
LA. Schimmenti and Christina G.S. Palmer
Index
473
MOLECULAR
DIAGNOSTICS
Techniques and Applications for the Clinical Laboratory
Edited by
Wayne
W. Grody,
MD.,
Ph.D. UCLA School of Medicine, Los Angeles, CA, USA
Robert M. Nakamura, M.D. Scripps Clinic, La Jolla, CA, USA
Frederick L. Kiechle, M.D., Ph.D. Pathology Consultants of South Broward, Memorial Healthcare System,
Hollywood, FL, USA
Charles Strom, M.D., Ph.D. Quest Diagnostics, San Juan Capistrano, CA, USA
•
Serves as the definitive reference source for molecular diagnostics worldwide
•
Covers a variety of state-of-the-art molecular techniques and applications, including next-generation sequencing,
microfluidics, tumor cell genotyping, molecular epidemiology testing of infections, and pharmacogenetics, in
addition to standard approaches for molecular testing in genetic, infectious and neoplastic diseases.
•
Discusses in detail pertinent regulatory, economic, quality assurance, and ethical issues that impact the field
Advances in genomic profiling of disease have transformed the field of molecular diagnostics, leading the way toward a
major revolution in clinical practice. While the range of tests for disease detection and staging is rapidly expanding, there
is greater need for guidance with regard to determining the appropriate tests to order and the interpretation of the results.
Molecular Diagnostics: Techniques and Applications for the Clinical Laboratory provides a complete guide to the use and
interpretation of molecular testing in the clinical setting. Beginning with an authoritative description of methodology and
expanded to highlight the newest techniques and applications in genetic disease, cancer, infectious disease and identity testing,
-
this book brings together contributions from leaders in practice and clinical resedrch. The inclusion of chapters on quality
assurance, regulatory, reimbursement and ethical issues distinguish this book as a comprehensive guide for those performing
molecular testing for clinical purposes. |
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indexdate | 2024-09-07T00:11:28Z |
institution | BVB |
isbn | 9780123694287 0123694280 |
language | English |
oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-017297019 |
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owner_facet | DE-526 DE-355 DE-BY-UBR |
physical | IX, 484 S. Ill., graph. Darst. |
publishDate | 2010 |
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publishDateSort | 2010 |
publisher | Elsevier, Acad. Press |
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spelling | Molecular diagnostics techniques and applications for the clinical laboratory Wayne W. Grody ... Amsterdam [u.a.] Elsevier, Acad. Press 2010 IX, 484 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Molekulare Diagnostik (DE-588)4589005-5 gnd rswk-swf Molekulare Diagnostik (DE-588)4589005-5 s DE-604 Grody, Wayne W. Sonstige oth Digitalisierung UB Regensburg application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=017297019&sequence=000003&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis Digitalisierung UB Regensburg application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=017297019&sequence=000004&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA Klappentext |
spellingShingle | Molecular diagnostics techniques and applications for the clinical laboratory Molekulare Diagnostik (DE-588)4589005-5 gnd |
subject_GND | (DE-588)4589005-5 |
title | Molecular diagnostics techniques and applications for the clinical laboratory |
title_auth | Molecular diagnostics techniques and applications for the clinical laboratory |
title_exact_search | Molecular diagnostics techniques and applications for the clinical laboratory |
title_full | Molecular diagnostics techniques and applications for the clinical laboratory Wayne W. Grody ... |
title_fullStr | Molecular diagnostics techniques and applications for the clinical laboratory Wayne W. Grody ... |
title_full_unstemmed | Molecular diagnostics techniques and applications for the clinical laboratory Wayne W. Grody ... |
title_short | Molecular diagnostics |
title_sort | molecular diagnostics techniques and applications for the clinical laboratory |
title_sub | techniques and applications for the clinical laboratory |
topic | Molekulare Diagnostik (DE-588)4589005-5 gnd |
topic_facet | Molekulare Diagnostik |
url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=017297019&sequence=000003&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=017297019&sequence=000004&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA |
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