Elements of synthesis planning:
Gespeichert in:
| 1. Verfasser: | |
|---|---|
| Format: | Buch |
| Sprache: | English |
| Veröffentlicht: |
Berlin [u.a.]
Springer
2009
|
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | X, 227 S. Ill. |
| ISBN: | 9783540792192 |
Internformat
MARC
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| 240 | 1 | 0 | |a Elemente der Syntheseplanung |
| 245 | 1 | 0 | |a Elements of synthesis planning |c R. W. Hoffmann |
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Datensatz im Suchindex
| _version_ | 1804137791690375168 |
|---|---|
| adam_text | Contents
1 Introduction 1
References 6
2 Functional Group Oriented Bond-Sets 9
2.1 Polar Bond Formation 9
2.1.1 Polar Synthons 12
2.1.2 Bond Formation Between Two Functional Groups .... 14
2.1.3 Umpolung 15
2.2 Bond-Sets According to Functional Group Presence 22
2.2.1 7,2-Relationship Between Two Functional Groups .... 22
2.2.2 7,4-Relationship Between Two Functional Groups .... 27
2.2.3 7,3-Relationship Between Two Functional Groups .... 34
2.2.4 7,5-(and 1,6-) Relationship Between Two Functional
Groups 37
2.2.5 Conjunctive Reagents 38
Problems 40
References 41
3 Skeleton Oriented Bond-Sets 47
3.1 The FGA-Strategy for Preparing Branched Skeletons 49
3.2 Symmetry in the Molecular Skeleton 58
Problems 61
References 61
4 Building Block Oriented Synthesis 65
Problems 70
References 71
x Contents
5 The Basis for Planning 73
Problems 79
References 79
6 Formation of Cyclic Structures 81
6.1 Anellated Bicycles and Anellated Polycycles 89
6.2 Bridged Bi- and Polycycles 97
6.3 Overbred Intermediates 106
Problems 110
References 112
7 Protecting Groups 119
Problems 129
References 130
8 Ranking of Synthesis Plans 133
Problems 142
References 144
9 Computer-Aided Synthesis Planning 145
References 148
10 Stereogenic Centers and Planning of Syntheses 149
Problems 161
References 161
11 Enjoying the Art of Synthesis 165
11.1 Strychnine 166
11.2 Colchicine 178
11.3 Dysidiolide 185
11.4 Asteriscanolide 190
11.5 Lepadiformine 195
References 200
12 Summary and Concluding Remarks 203
References 205
13 Solutions to Problems 207
References 223
Index 225
|
| adam_txt |
Contents
1 Introduction 1
References 6
2 Functional Group Oriented Bond-Sets 9
2.1 Polar Bond Formation 9
2.1.1 Polar Synthons 12
2.1.2 Bond Formation Between Two Functional Groups . 14
2.1.3 Umpolung 15
2.2 Bond-Sets According to Functional Group Presence 22
2.2.1 7,2-Relationship Between Two Functional Groups . 22
2.2.2 7,4-Relationship Between Two Functional Groups . 27
2.2.3 7,3-Relationship Between Two Functional Groups . 34
2.2.4 7,5-(and 1,6-) Relationship Between Two Functional
Groups 37
2.2.5 Conjunctive Reagents 38
Problems 40
References 41
3 Skeleton Oriented Bond-Sets 47
3.1 The FGA-Strategy for Preparing Branched Skeletons 49
3.2 Symmetry in the Molecular Skeleton 58
Problems 61
References 61
4 Building Block Oriented Synthesis 65
Problems 70
References 71
x Contents
5 The Basis for Planning 73
Problems 79
References 79
6 Formation of Cyclic Structures 81
6.1 Anellated Bicycles and Anellated Polycycles 89
6.2 Bridged Bi- and Polycycles 97
6.3 "Overbred" Intermediates 106
Problems 110
References 112
7 Protecting Groups 119
Problems 129
References 130
8 Ranking of Synthesis Plans 133
Problems 142
References 144
9 Computer-Aided Synthesis Planning 145
References 148
10 Stereogenic Centers and Planning of Syntheses 149
Problems 161
References 161
11 Enjoying the Art of Synthesis 165
11.1 Strychnine 166
11.2 Colchicine 178
11.3 Dysidiolide 185
11.4 Asteriscanolide 190
11.5 Lepadiformine 195
References 200
12 Summary and Concluding Remarks 203
References 205
13 Solutions to Problems 207
References 223
Index 225 |
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| discipline | Chemie / Pharmazie Chemie |
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| illustrated | Illustrated |
| index_date | 2024-07-02T21:25:44Z |
| indexdate | 2024-07-09T21:17:55Z |
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| isbn | 9783540792192 |
| language | English |
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| spelling | Hoffmann, Reinhard W. 1933- Verfasser (DE-588)107458640 aut Elemente der Syntheseplanung Elements of synthesis planning R. W. Hoffmann Berlin [u.a.] Springer 2009 X, 227 S. Ill. txt rdacontent n rdamedia nc rdacarrier Organische Synthese (DE-588)4075695-6 gnd rswk-swf Planung (DE-588)4046235-3 gnd rswk-swf Syntheseplanung (DE-588)4347401-9 gnd rswk-swf Organische Synthese (DE-588)4075695-6 s Syntheseplanung (DE-588)4347401-9 s DE-604 Planung (DE-588)4046235-3 s 1\p DE-604 Erscheint auch als Online-Ausgabe 978-3-540-79220-8 HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=016589073&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
| spellingShingle | Hoffmann, Reinhard W. 1933- Elements of synthesis planning Organische Synthese (DE-588)4075695-6 gnd Planung (DE-588)4046235-3 gnd Syntheseplanung (DE-588)4347401-9 gnd |
| subject_GND | (DE-588)4075695-6 (DE-588)4046235-3 (DE-588)4347401-9 |
| title | Elements of synthesis planning |
| title_alt | Elemente der Syntheseplanung |
| title_auth | Elements of synthesis planning |
| title_exact_search | Elements of synthesis planning |
| title_exact_search_txtP | Elements of synthesis planning |
| title_full | Elements of synthesis planning R. W. Hoffmann |
| title_fullStr | Elements of synthesis planning R. W. Hoffmann |
| title_full_unstemmed | Elements of synthesis planning R. W. Hoffmann |
| title_short | Elements of synthesis planning |
| title_sort | elements of synthesis planning |
| topic | Organische Synthese (DE-588)4075695-6 gnd Planung (DE-588)4046235-3 gnd Syntheseplanung (DE-588)4347401-9 gnd |
| topic_facet | Organische Synthese Planung Syntheseplanung |
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