Verfügbarkeit: Clinical bioinformatics

Clinical bioinformatics:

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Bibliographische Detailangaben
Format:	Buch
Sprache:	English
Veröffentlicht:	Totowa, N.J. Humana 2008
Schriftenreihe:	Methods in molecular medicine 141
Schlagworte:	Bio-informatique Génomique - Informatique Datenverarbeitung Bioinformatics Computational biology Genomics > Data processing Computational Biology Genetic Techniques Genomics > methods Microarray Analysis > methods Bioinformatik Molekulare Bioinformatik Aufsatzsammlung
Online-Zugang:	Publisher description Table of contents only Inhaltsverzeichnis
Beschreibung:	XI, 382 S. graph. Darst.
ISBN:	9781588297914

Internformat

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Datensatz im Suchindex

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adam_text	Contents Preface ..................................................................... v Contributors ................................................................ ix 1. In Silico Gene Discovery Bing Yu .......................................................... 1 2. Whole Genome-Wide Association Study Using Affymetrix SNP Chip: A Two-Stage Sequential Selection Method to Identify Genes That Increase the Risk of Developing Complex Diseases Howard H. Yang, Nan Ни, Phiiip R. Taylor, and Maxwell P. Lee .. 23 3. Utilizing НарМар and Tagging SNPs Christopher A. Haiman and Daniel O. Stram ...................... 37 4. Measuring the Effects of Genes and Environment on Complex Traits Jennifer H. Barrett ................................................ 55 5. Microarrays — Planning Your Experiment Jean Yee Hwa Yang .............................................. 71 6. Clinical Uses of Microarrays in Cancer Research Carl Virtanen and James Woodgett ............................... 87 7. Microarrays — Analysis of Signaling Pathways Anassuya Ramachandran, Michael A. Black, Andrew N. Shelling, and Donald R. Love ............................................ 115 8. Microarrays — Identifying Molecular Portraits for Prostate Tumors with Different Gleason Patterns Alexandre Mendes, Rodney J. Scott, and Pablo Moscato ........... 131 9. Microarrays for the Study of Viral Gene Expression During Human Cytomegalovirus Latent Infection Barry Slobedman and Allen K. L. Cheung ......................... 153 10. Computer-Assisted Reading of DNA Sequences Huong Le, Marcus Hinchcliffe, Bing Yu, and Ronald J . A. Trent ... 177 11. Evaluating DNA Sequence Variants of Unknown Biological Significance Scott A. Grist, Andrew Dubowsky, and Graeme Suthers ........... 199 vii viü Contents 12. Developing a DNA Variant Database DavidC. Y.Fung ................................................. 219 13. Protein Comparative Sequence Analysis and Computer Modeling Brett D. Hambly, Cecily E. Oakley, and Piotr G. Fajer ............. 245 14. Identification and Characterization of Microbial Proteins Using Peptide Mass Fingerprinting Strategies Jonathan W. Arthur ............................................... 257 15. Statistical Analysis of Image Data Provided by Two-Dimensional Gel Electrophoresis for Discovery Proteomics Ben Crossett, Alistair V. G. Edwards, Melanie Y. White, and Stuart J. Cordwell......................................... 271 16. Online Resources for the Molecular Contextualization of Disease Chi N. I. Pang and Marc R. Wilkins ............................... 287 17. Web-Based Resources for Clinical Bioinformatics Anthony M. Joshua and Paul С Boutros.......................... 309 18. Developing Decision Support Systems in Clinical Bioinformatics Vitali Sintchenko and Enrico Colera .............................. 331 19. eConsulting Siaw-Teng Liaw and Peter Schattner .............................. 353 Index ..................................................................... 375
adam_txt	Contents Preface . v Contributors . ix 1. In Silico Gene Discovery Bing Yu . 1 2. Whole Genome-Wide Association Study Using Affymetrix SNP Chip: A Two-Stage Sequential Selection Method to Identify Genes That Increase the Risk of Developing Complex Diseases Howard H. Yang, Nan Ни, Phiiip R. Taylor, and Maxwell P. Lee . 23 3. Utilizing НарМар and Tagging SNPs Christopher A. Haiman and Daniel O. Stram . 37 4. Measuring the Effects of Genes and Environment on Complex Traits Jennifer H. Barrett . 55 5. Microarrays — Planning Your Experiment Jean Yee Hwa Yang . 71 6. Clinical Uses of Microarrays in Cancer Research Carl Virtanen and James Woodgett . 87 7. Microarrays — Analysis of Signaling Pathways Anassuya Ramachandran, Michael A. Black, Andrew N. Shelling, and Donald R. Love . 115 8. Microarrays — Identifying Molecular Portraits for Prostate Tumors with Different Gleason Patterns Alexandre Mendes, Rodney J. Scott, and Pablo Moscato . 131 9. Microarrays for the Study of Viral Gene Expression During Human Cytomegalovirus Latent Infection Barry Slobedman and Allen K. L. Cheung . 153 10. Computer-Assisted Reading of DNA Sequences Huong Le, Marcus Hinchcliffe, Bing Yu, and Ronald J . A. Trent . 177 11. Evaluating DNA Sequence Variants of Unknown Biological Significance Scott A. Grist, Andrew Dubowsky, and Graeme Suthers . 199 vii viü Contents 12. Developing a DNA Variant Database DavidC. Y.Fung . 219 13. Protein Comparative Sequence Analysis and Computer Modeling Brett D. Hambly, Cecily E. Oakley, and Piotr G. Fajer . 245 14. Identification and Characterization of Microbial Proteins Using Peptide Mass Fingerprinting Strategies Jonathan W. Arthur . 257 15. Statistical Analysis of Image Data Provided by Two-Dimensional Gel Electrophoresis for Discovery Proteomics Ben Crossett, Alistair V. G. Edwards, Melanie Y. White, and Stuart J. Cordwell. 271 16. Online Resources for the Molecular Contextualization of Disease Chi N. I. Pang and Marc R. Wilkins . 287 17. Web-Based Resources for Clinical Bioinformatics Anthony M. Joshua and Paul С Boutros. 309 18. Developing Decision Support Systems in Clinical Bioinformatics Vitali Sintchenko and Enrico Colera . 331 19. eConsulting Siaw-Teng Liaw and Peter Schattner . 353 Index . 375
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spelling	Clinical bioinformatics ed. by Ronald J. A. Trent Totowa, N.J. Humana 2008 XI, 382 S. graph. Darst. txt rdacontent n rdamedia nc rdacarrier Methods in molecular medicine 141 Bio-informatique Génomique - Informatique Datenverarbeitung Bioinformatics Computational biology Genomics Data processing Computational Biology Genetic Techniques Genomics methods Microarray Analysis methods Bioinformatik (DE-588)4611085-9 gnd rswk-swf Molekulare Bioinformatik (DE-588)4531334-9 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Bioinformatik (DE-588)4611085-9 s DE-604 Molekulare Bioinformatik (DE-588)4531334-9 s Trent, Ronald J. Sonstige oth Erscheint auch als Online-Ausgabe 978-1-603-27148-6 Methods in molecular medicine 141 (DE-604)BV011334960 141 http://www.loc.gov/catdir/enhancements/fy0825/2007933471-d.html Publisher description http://www.loc.gov/catdir/enhancements/fy0825/2007933471-t.html Table of contents only Digitalisierung UB Regensburg application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=016584180&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis
spellingShingle	Clinical bioinformatics Methods in molecular medicine Bio-informatique Génomique - Informatique Datenverarbeitung Bioinformatics Computational biology Genomics Data processing Computational Biology Genetic Techniques Genomics methods Microarray Analysis methods Bioinformatik (DE-588)4611085-9 gnd Molekulare Bioinformatik (DE-588)4531334-9 gnd
subject_GND	(DE-588)4611085-9 (DE-588)4531334-9 (DE-588)4143413-4
title	Clinical bioinformatics
title_auth	Clinical bioinformatics
title_exact_search	Clinical bioinformatics
title_exact_search_txtP	Clinical bioinformatics
title_full	Clinical bioinformatics ed. by Ronald J. A. Trent
title_fullStr	Clinical bioinformatics ed. by Ronald J. A. Trent
title_full_unstemmed	Clinical bioinformatics ed. by Ronald J. A. Trent
title_short	Clinical bioinformatics
title_sort	clinical bioinformatics
topic	Bio-informatique Génomique - Informatique Datenverarbeitung Bioinformatics Computational biology Genomics Data processing Computational Biology Genetic Techniques Genomics methods Microarray Analysis methods Bioinformatik (DE-588)4611085-9 gnd Molekulare Bioinformatik (DE-588)4531334-9 gnd
topic_facet	Bio-informatique Génomique - Informatique Datenverarbeitung Bioinformatics Computational biology Genomics Data processing Computational Biology Genetic Techniques Genomics methods Microarray Analysis methods Bioinformatik Molekulare Bioinformatik Aufsatzsammlung
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work_keys_str_mv	AT trentronaldj clinicalbioinformatics

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