Nucleic acids in innate immunity:
Gespeichert in:
| Weitere Verfasser: | |
|---|---|
| Format: | Buch |
| Sprache: | English |
| Veröffentlicht: |
Boca Raton [u.a.]
CRC Press
2008
|
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | Includes bibliographical references and index |
| Beschreibung: | XV, 286 S. Ill. 24cm |
| ISBN: | 1420068253 9781420068252 |
Internformat
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| 245 | 1 | 0 | |a Nucleic acids in innate immunity |c ed. by Ken J. Ishii ... |
| 264 | 1 | |a Boca Raton [u.a.] |b CRC Press |c 2008 | |
| 300 | |a XV, 286 S. |b Ill. |c 24cm | ||
| 336 | |b txt |2 rdacontent | ||
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| 500 | |a Includes bibliographical references and index | ||
| 650 | 2 | |a Immunity, Natural |a physiology | |
| 650 | 2 | |a DNA |a immunology | |
| 650 | 2 | |a RNA |a immunology | |
| 650 | 2 | |a Receptors, Pattern Recognition |a immunology | |
| 650 | 2 | |a Self Tolerance | |
| 650 | 2 | |a Autoimmunity | |
| 650 | 4 | |a Natural immunity | |
| 650 | 4 | |a Nucleic acids | |
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Datensatz im Suchindex
| _version_ | 1804137773611876352 |
|---|---|
| adam_text | Contents
Preface vii
Editors xi
Contributors xiii
Section I
Roles of Nucleic Acids in Immunity
Chapter 1 Structural Analysis of Toll-Like Receptors 3
Jungwoo Choe and Ian A. Wilson
Chapter 2 Antiviral Signaling through TLRs and RLHs 17
Tarn Kawai
Chapter 3 Recognition of Virus Invasion by Toll-Like Receptors and RIG-
I-Like Helicases 31
Hiroki Kato and Osamu Takeuchi
Chapter 4 Characteristics of Dendritic Cell Responses to Nucleic Acids 43
Tsuneyasu Kaisho, Takahiro Sugiyama, and Katsuaki Hoshino
Chapter 5 Dendritic Cells as Sensors for Foreign and Self Nucleic Acids 59
Anne Krug and Wolfgang Reindl
Section II
Mechanisms and Therapeutic Applications of Immunomodulatory DNA
Chapter 6 Natural DNA Recognition by Toll-Like Receptor 9 Does Not
Rely upon CpG Motifs: Role of Endosomal Compartmentation 77
Tobias Haas, Frank Schmitz, Antje Heit, and Hermann Wagner
Chapter 7 Discrimination of Self and Non-Self DNAs 85
Katryn J. Stacey, Francis Clark, Greg R. Young, Tara L. Roberts
v
Chapter 8 Therapeutic Potential of Immunosuppressive Oligonucleotides
Expressing TTAGGG Motifs 101
Dennis M. Klinman, Debbie Currie, Chiaki Fujimoto, Igal
Gery, and Hidekazu Shirota
Chapter 9 Structure/Function of IFNa-Inducing CpG ODNs 113
Daniela Verthelyi and Montserrat Puig
Chapter 10 Clinical Development of Oligodeoxynucleotide TLR9 Agonists .... 129
Julie L. Hirnes and Arthur M. Krieg
Chapter 11 Prospects for TLR9-Based Immunotherapy for Asthma
and Allergy 145
David Broide
Chapter 12 Toll-Like Receptors in Development of Systemic Autoimmune
Disease: In Vitro Artifact or In Vivo Paradigm? 159
Ann Marshak-Rothstein and Mark J. Shlomchik
Chapter 13 Impacts of Nucleoside Modification on RNA-Mediated
Activation of Toll-Like Receptors 171
Katalin Karikö and Drew Weissman
Chapter 14 Activation of Innate Pattern Recognition Pathways by Single-
Stranded Ribonucleic Acids 189
Sandra S. Diebold
Chapter 15 RNA Interference in Scope of Immune System 207
Andrea Ablasser, Günther Hartmann, and Veit Hornung
Chapter 16 Recognition of RNA and Synthetic Compounds by TLR7
andTLR8 227
Svetlana Hamm and Stefan Bauer
Chapter 17 Helicases at Frontline of RNA Virus Recognition 241
Leonid Gitlin and Marco Colonna
Index 273
|
| adam_txt |
Contents
Preface vii
Editors xi
Contributors xiii
Section I
Roles of Nucleic Acids in Immunity
Chapter 1 Structural Analysis of'Toll-Like Receptors 3
Jungwoo Choe and Ian A. Wilson
Chapter 2 Antiviral Signaling through TLRs and RLHs 17
Tarn Kawai
Chapter 3 Recognition of Virus Invasion by Toll-Like Receptors and RIG-
I-Like Helicases 31
Hiroki Kato and Osamu Takeuchi
Chapter 4 Characteristics of Dendritic Cell Responses to Nucleic Acids 43
Tsuneyasu Kaisho, Takahiro Sugiyama, and Katsuaki Hoshino
Chapter 5 Dendritic Cells as Sensors for Foreign and Self Nucleic Acids 59
Anne Krug and Wolfgang Reindl
Section II
Mechanisms and Therapeutic Applications of Immunomodulatory DNA
Chapter 6 Natural DNA Recognition by Toll-Like Receptor 9 Does Not
Rely upon CpG Motifs: Role of Endosomal Compartmentation 77
Tobias Haas, Frank Schmitz, Antje Heit, and Hermann Wagner
Chapter 7 Discrimination of Self and Non-Self DNAs 85
Katryn J. Stacey, Francis Clark, Greg R. Young, Tara L. Roberts
v
Chapter 8 Therapeutic Potential of Immunosuppressive Oligonucleotides
Expressing TTAGGG Motifs 101
Dennis M. Klinman, Debbie Currie, Chiaki Fujimoto, Igal
Gery, and Hidekazu Shirota
Chapter 9 Structure/Function of IFNa-Inducing CpG ODNs 113
Daniela Verthelyi and Montserrat Puig
Chapter 10 Clinical Development of Oligodeoxynucleotide TLR9 Agonists . 129
Julie L. Hirnes and Arthur M. Krieg
Chapter 11 Prospects for TLR9-Based Immunotherapy for Asthma
and Allergy 145
David Broide
Chapter 12 Toll-Like Receptors in Development of Systemic Autoimmune
Disease: In Vitro Artifact or In Vivo Paradigm? 159
Ann Marshak-Rothstein and Mark J. Shlomchik
Chapter 13 Impacts of Nucleoside Modification on RNA-Mediated
Activation of Toll-Like Receptors 171
Katalin Karikö and Drew Weissman
Chapter 14 Activation of Innate Pattern Recognition Pathways by Single-
Stranded Ribonucleic Acids 189
Sandra S. Diebold
Chapter 15 RNA Interference in Scope of Immune System 207
Andrea Ablasser, Günther Hartmann, and Veit Hornung
Chapter 16 Recognition of RNA and Synthetic Compounds by TLR7
andTLR8 227
Svetlana Hamm and Stefan Bauer
Chapter 17 Helicases at Frontline of RNA Virus Recognition 241
Leonid Gitlin and Marco Colonna
Index 273 |
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| discipline | Chemie Medizin |
| discipline_str_mv | Chemie Medizin |
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| index_date | 2024-07-02T21:21:19Z |
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| isbn | 1420068253 9781420068252 |
| language | English |
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| spelling | Nucleic acids in innate immunity ed. by Ken J. Ishii ... Boca Raton [u.a.] CRC Press 2008 XV, 286 S. Ill. 24cm txt rdacontent n rdamedia nc rdacarrier Includes bibliographical references and index Immunity, Natural physiology DNA immunology RNA immunology Receptors, Pattern Recognition immunology Self Tolerance Autoimmunity Natural immunity Nucleic acids Angeborene Immunität (DE-588)4739713-5 gnd rswk-swf Nucleinsäuren (DE-588)4172117-2 gnd rswk-swf Immunreaktion (DE-588)4133841-8 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Angeborene Immunität (DE-588)4739713-5 s Nucleinsäuren (DE-588)4172117-2 s DE-604 Immunreaktion (DE-588)4133841-8 s b DE-604 Ishii, Ken J. edt HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=016577299&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Nucleic acids in innate immunity Immunity, Natural physiology DNA immunology RNA immunology Receptors, Pattern Recognition immunology Self Tolerance Autoimmunity Natural immunity Nucleic acids Angeborene Immunität (DE-588)4739713-5 gnd Nucleinsäuren (DE-588)4172117-2 gnd Immunreaktion (DE-588)4133841-8 gnd |
| subject_GND | (DE-588)4739713-5 (DE-588)4172117-2 (DE-588)4133841-8 (DE-588)4143413-4 |
| title | Nucleic acids in innate immunity |
| title_auth | Nucleic acids in innate immunity |
| title_exact_search | Nucleic acids in innate immunity |
| title_exact_search_txtP | Nucleic acids in innate immunity |
| title_full | Nucleic acids in innate immunity ed. by Ken J. Ishii ... |
| title_fullStr | Nucleic acids in innate immunity ed. by Ken J. Ishii ... |
| title_full_unstemmed | Nucleic acids in innate immunity ed. by Ken J. Ishii ... |
| title_short | Nucleic acids in innate immunity |
| title_sort | nucleic acids in innate immunity |
| topic | Immunity, Natural physiology DNA immunology RNA immunology Receptors, Pattern Recognition immunology Self Tolerance Autoimmunity Natural immunity Nucleic acids Angeborene Immunität (DE-588)4739713-5 gnd Nucleinsäuren (DE-588)4172117-2 gnd Immunreaktion (DE-588)4133841-8 gnd |
| topic_facet | Immunity, Natural physiology DNA immunology RNA immunology Receptors, Pattern Recognition immunology Self Tolerance Autoimmunity Natural immunity Nucleic acids Angeborene Immunität Nucleinsäuren Immunreaktion Aufsatzsammlung |
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