Protein protein interactions as new drug targets:
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
Berlin [u.a.]
Springer
2008
|
| Schriftenreihe: | Handbook of experimental pharmacology
186 |
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | XV, 512 S. Ill., graph. Darst. |
| ISBN: | 9783540728429 |
Internformat
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| 245 | 1 | 0 | |a Protein protein interactions as new drug targets |c Enno Klussmann ... ed. Contributors E. M. Aandahl ... |
| 264 | 1 | |a Berlin [u.a.] |b Springer |c 2008 | |
| 300 | |a XV, 512 S. |b Ill., graph. Darst. | ||
| 336 | |b txt |2 rdacontent | ||
| 337 | |b n |2 rdamedia | ||
| 338 | |b nc |2 rdacarrier | ||
| 490 | 1 | |a Handbook of experimental pharmacology |v 186 | |
| 650 | 2 | |a Nerve Tissue Proteins | |
| 650 | 7 | |a Signal Transduction |2 cabt | |
| 650 | 7 | |a Proteins |2 cabt | |
| 650 | 7 | |a Interactions |2 cabt | |
| 650 | 4 | |a Drug targeting | |
| 650 | 4 | |a Protein-protein interactions | |
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| 689 | 0 | 1 | |a Protein-Protein-Wechselwirkung |0 (DE-588)4745193-2 |D s |
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| 700 | 1 | |a Klussmann, Enno |d 1964- |e Sonstige |0 (DE-588)114794073 |4 oth | |
| 700 | 1 | |a Aandahl, Einar Martin |e Sonstige |0 (DE-588)135774233 |4 oth | |
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| 999 | |a oai:aleph.bib-bvb.de:BVB01-016555169 | ||
Datensatz im Suchindex
| _version_ | 1804137739940003840 |
|---|---|
| adam_text | Contents
Part I Organization of Scaffolds
A-Kinase Anchoring Proteins as the Basis for cAMP Signaling
........ 3
K.L. Dodge-Kafka, A. Bauman,
and M.S. Kapiloff
Arrestins as Multi-Functional Signaling Adaptors
................... 15
V.V. Gurevich,
E.V.
Gurevich,
and W.M. Cleghorn
Role of Ena/VASP Proteins in Homeostasisand Disease
............... 39
G.
Pula
and M.
Krause
Scaffold/Matrix Attachment Regions (S/MARs):
Relevance for Disease and Therapy
................................ 67
A. Gluch, M. Vidakovic, and J. Bode
Clathrin/AP-2-DependentEndocytosis:
A Novel Playground for the Pharmacological Toolbox?
............... 105
C. Rodemer and V. Haucke
Part II Scaffolding Proteins and Cellular Signalling
PDE4 Associates with Different Scaffolding
Proteins: Modulating Interactions as Treatment for Certain Diseases
... 125
A.C.
McCahill, E. Huston, X. Li,
and M.D. Houslay
G-Protein-Coupled Receptor-Signaling Components in Membrane
Raft and Caveolae Microdomains
................................. 167
H.H.
Patel,
F.
Murray, and
P.A. Insel
vjjj Contents
Protein Scaffolds,
Lipid
Domains and Substrate
Recognition in Protein Kinase
С
Function. Implications
for Rational Drug Design
........................................ 185
J.W. Walker
Compartmentalised
МАРК
Pathways
............................. 205
M.D. Brown and D.B. Sacks
Dynamic Protein Complexes Regulate
NF
-кВ
Signaling
.............. 237
E. Wegener and D.
Krappmann
An Oncogenic Hub:
ß-Catenin
as a Molecular Target
for Cancer Therapeutics
......................................... 261
K.-I.
Такетата,
M.
Ohmitsu, and F.-Q. Li
A Toolkit for Real-Time Detection of cAMP:
Insights into Compartmentalized Signaling
......................... 285
M.
Berrera,
G. Dodoni, S. Monterisi,
V. Pertegato, I. Zamparo, and M.
Zaceólo
Part III Cell Type-Specific Anchoring
Scaffolding Proteins in Cardiac Myocytes
.......................... 301
N.L. Chudasama,
S.O.
Marx, and S.F. Steinberg
Molecular Architecture of Signal Complexes
Regulating Immune Cell Function
................................ 327
K.M.
Torgersen, E.M. Aandahl, and
K. Taskén
Scaffolding Proteins at the Postsynaptic Density:Shank
as the Architectural Framework
.................................. 365
H.J. Kreienkamp
Part IV Interference with Protein-Protein Interaction
Sites as a New Pharmacological Concept
Domains Mediate Protein-Protein Interactions
and Nucleate Protein Assemblies
.................................. 383
S. Costa and G.
Cesaren!
Proline-Rich Sequence Recognition Domains
(PRD):
Ligands, Function and Inhibition
................................. 407
C.
Freund, H.G. Schmalz, J. Sticht, and
R.
Kühne
Contents ix
Chemical Inhibition
Through Conformational Stabilization
of Rho GTPase Effectors
........................................ 431
S.W.
Deacon and J.R. Peterson
Pharmacological Interference with Protein-Protein Interactions
Mediated by Coiled-Coil Motifs
.................................. 461
H.M. Strauss and S. Keller
Direct AKAP-Mediated Protein-Protein Interactions
as Potential Drug Targets
........................................ 483
C.
Hundsracker
and E. Klussmann
Index
......................................................... 505
|
| adam_txt |
Contents
Part I Organization of Scaffolds
A-Kinase Anchoring Proteins as the Basis for cAMP Signaling
. 3
K.L. Dodge-Kafka, A. Bauman,
and M.S. Kapiloff
Arrestins as Multi-Functional Signaling Adaptors
. 15
V.V. Gurevich,
E.V.
Gurevich,
and W.M. Cleghorn
Role of Ena/VASP Proteins in Homeostasisand Disease
. 39
G.
Pula
and M.
Krause
Scaffold/Matrix Attachment Regions (S/MARs):
Relevance for Disease and Therapy
. 67
A. Gluch, M. Vidakovic, and J. Bode
Clathrin/AP-2-DependentEndocytosis:
A Novel Playground for the Pharmacological Toolbox?
. 105
C. Rodemer and V. Haucke
Part II Scaffolding Proteins and Cellular Signalling
PDE4 Associates with Different Scaffolding
Proteins: Modulating Interactions as Treatment for Certain Diseases
. 125
A.C.
McCahill, E. Huston, X. Li,
and M.D. Houslay
G-Protein-Coupled Receptor-Signaling Components in Membrane
Raft and Caveolae Microdomains
. 167
H.H.
Patel,
F.
Murray, and
P.A. Insel
vjjj Contents
Protein Scaffolds,
Lipid
Domains and Substrate
Recognition in Protein Kinase
С
Function. Implications
for Rational Drug Design
. 185
J.W. Walker
Compartmentalised
МАРК
Pathways
. 205
M.D. Brown and D.B. Sacks
Dynamic Protein Complexes Regulate
NF
-кВ
Signaling
. 237
E. Wegener and D.
Krappmann
An Oncogenic Hub:
ß-Catenin
as a Molecular Target
for Cancer Therapeutics
. 261
K.-I.
Такетата,
M.
Ohmitsu, and F.-Q. Li
A Toolkit for Real-Time Detection of cAMP:
Insights into Compartmentalized Signaling
. 285
M.
Berrera,
G. Dodoni, S. Monterisi,
V. Pertegato, I. Zamparo, and M.
Zaceólo
Part III Cell Type-Specific Anchoring
Scaffolding Proteins in Cardiac Myocytes
. 301
N.L. Chudasama,
S.O.
Marx, and S.F. Steinberg
Molecular Architecture of Signal Complexes
Regulating Immune Cell Function
. 327
K.M.
Torgersen, E.M. Aandahl, and
K. Taskén
Scaffolding Proteins at the Postsynaptic Density:Shank
as the Architectural Framework
. 365
H.J. Kreienkamp
Part IV Interference with Protein-Protein Interaction
Sites as a New Pharmacological Concept
Domains Mediate Protein-Protein Interactions
and Nucleate Protein Assemblies
. 383
S. Costa and G.
Cesaren!
Proline-Rich Sequence Recognition Domains
(PRD):
Ligands, Function and Inhibition
. 407
C.
Freund, H.G. Schmalz, J. Sticht, and
R.
Kühne
Contents ix
Chemical Inhibition
Through Conformational Stabilization
of Rho GTPase Effectors
. 431
S.W.
Deacon and J.R. Peterson
Pharmacological Interference with Protein-Protein Interactions
Mediated by Coiled-Coil Motifs
. 461
H.M. Strauss and S. Keller
Direct AKAP-Mediated Protein-Protein Interactions
as Potential Drug Targets
. 483
C.
Hundsracker
and E. Klussmann
Index
. 505 |
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| dewey-search | 615.7 |
| dewey-sort | 3615.7 |
| dewey-tens | 610 - Medicine and health |
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| index_date | 2024-07-02T21:12:52Z |
| indexdate | 2024-07-09T21:17:05Z |
| institution | BVB |
| isbn | 9783540728429 |
| language | English |
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| physical | XV, 512 S. Ill., graph. Darst. |
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| series | Handbook of experimental pharmacology |
| series2 | Handbook of experimental pharmacology |
| spelling | Protein protein interactions as new drug targets Enno Klussmann ... ed. Contributors E. M. Aandahl ... Berlin [u.a.] Springer 2008 XV, 512 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Handbook of experimental pharmacology 186 Nerve Tissue Proteins Signal Transduction cabt Proteins cabt Interactions cabt Drug targeting Protein-protein interactions Protein-Protein-Wechselwirkung (DE-588)4745193-2 gnd rswk-swf Targeted drug delivery (DE-588)4302415-4 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Targeted drug delivery (DE-588)4302415-4 s Protein-Protein-Wechselwirkung (DE-588)4745193-2 s DE-604 Klussmann, Enno 1964- Sonstige (DE-588)114794073 oth Aandahl, Einar Martin Sonstige (DE-588)135774233 oth Erscheint auch als Online-Ausgabe 978-3-540-72843-6 Handbook of experimental pharmacology 186 (DE-604)BV002390716 186 Digitalisierung UB Regensburg application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=016555169&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Protein protein interactions as new drug targets Handbook of experimental pharmacology Nerve Tissue Proteins Signal Transduction cabt Proteins cabt Interactions cabt Drug targeting Protein-protein interactions Protein-Protein-Wechselwirkung (DE-588)4745193-2 gnd Targeted drug delivery (DE-588)4302415-4 gnd |
| subject_GND | (DE-588)4745193-2 (DE-588)4302415-4 (DE-588)4143413-4 |
| title | Protein protein interactions as new drug targets |
| title_auth | Protein protein interactions as new drug targets |
| title_exact_search | Protein protein interactions as new drug targets |
| title_exact_search_txtP | Protein protein interactions as new drug targets |
| title_full | Protein protein interactions as new drug targets Enno Klussmann ... ed. Contributors E. M. Aandahl ... |
| title_fullStr | Protein protein interactions as new drug targets Enno Klussmann ... ed. Contributors E. M. Aandahl ... |
| title_full_unstemmed | Protein protein interactions as new drug targets Enno Klussmann ... ed. Contributors E. M. Aandahl ... |
| title_short | Protein protein interactions as new drug targets |
| title_sort | protein protein interactions as new drug targets |
| topic | Nerve Tissue Proteins Signal Transduction cabt Proteins cabt Interactions cabt Drug targeting Protein-protein interactions Protein-Protein-Wechselwirkung (DE-588)4745193-2 gnd Targeted drug delivery (DE-588)4302415-4 gnd |
| topic_facet | Nerve Tissue Proteins Signal Transduction Proteins Interactions Drug targeting Protein-protein interactions Protein-Protein-Wechselwirkung Targeted drug delivery Aufsatzsammlung |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=016555169&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
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