Gene therapy for renal diseases and transplantation: 6 tables
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
Basel [u.a.]
Karger
2008
|
| Schriftenreihe: | Contributions to nephrology
159 |
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis Klappentext |
| Beschreibung: | Includes bibliographical references and indexes |
| Beschreibung: | VIII, 167 S. Ill., graph. Darst. |
| ISBN: | 9783805585057 3805585055 |
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| 264 | 1 | |a Basel [u.a.] |b Karger |c 2008 | |
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| 490 | 1 | |a Contributions to nephrology |v 159 | |
| 500 | |a Includes bibliographical references and indexes | ||
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| 650 | 4 | |a Gene therapy | |
| 650 | 4 | |a Graft Rejection - therapy | |
| 650 | 4 | |a Graft rejection - Prevention | |
| 650 | 4 | |a Kidney Diseases - therapy | |
| 650 | 4 | |a Kidney Transplantation | |
| 650 | 4 | |a Kidneys - Diseases - Gene therapy | |
| 650 | 4 | |a Kidneys - Transplantation - Genetic aspects | |
| 650 | 4 | |a Kidneys |x Diseases |x Gene therapy | |
| 650 | 4 | |a Kidneys |x Transplantation |x Genetic aspects | |
| 650 | 4 | |a Graft rejection |x Prevention | |
| 650 | 4 | |a Gene therapy | |
| 650 | 4 | |a Kidney Diseases |x therapy | |
| 650 | 4 | |a Gene Therapy | |
| 650 | 4 | |a Graft Rejection |x therapy | |
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Datensatz im Suchindex
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| adam_text | Contents
Vii
Preface
Benigni,
Α.;
Remuzzi, G. (Bergamo)
1
Renal Diseases as Targets of Gene Therapy
Phillips,
В.;
Giannoukakis,
Ν.;
Trucco,
M.
(Pittsburgh, Pa.)
13
Nonviral Gene Delivery
Akita, H.; Harashima, H. (Sapporo/Saitama)
30
Retrovirus
Vectors
Lech, P.; Somia, N.V. (Minneapolis, Minn.)
47
Adenovirus Vectors for Renal-Targeted Gene Delivery
Appiedorn,
D.M.;
Seregin, S.;
Amalfitano,
A. (East Lansing, Mich.)
63
Adeno-Associated Virus Vectors: Versatile Tools for in vfwo Gene
Transfer
Zentilin, L.;
Giacca,
M.
(Trieste)
78
RNA
Interference in Research and Therapy of Renal Diseases
Rácz,
Z.;
Hamar,
P. (Budapest)
96
Gene Therapy for Acute Renal Failure
Torras,
J.;
Cruzado, J.M.; Herrero-Fresneda, I.; Grinyo,
J.M.
(Barcelona)
109
Chronic Deteriorating Renal Function and Renal Fibrosis
¡saka. Y.;
Такаћага,
S.;
Imai,
E. (Suita)
122
Ailograft Rejection: Acute and Chronic Studies
Tomasoni, S.; Remuzzi, G.;
Benigni,
A. (Bergamo)
135
Gene Therapy for Renal Cancer
Haviv, Y.S. (Jerusalem);
Curiei, D.T.
(Birmingham, Ala.)
151
HIV-Associated Nephropathy
Wyatt,
СМ.;
Rosenstiel, P.E.;
Klotman,
P.E. (New York, N.Y.)
162
Author
Index
163
Subject
Index
Contents
VI
159
Gene Therapy for Renal Diseases and Transplantation
Editors:
A. Benigni,
G. Remuzzi,
Bergamo
VIII + 168
p.,
15
fig.,
4
in color,
б
tab., hard cover,
2008.
ISBN
978-3-8055-8505-7
Initially conceived as a strategy to remedy inherited genetic disorders, gene therapy has been
successfully applied in the last decade to ameliorate the renal function compromised by pro¬
gressive renal diseases and to prevent kidney ailograft rejection in experimental animals.
In the present book, world-renowned experts are presenting new insights into viral and non-
viral systems used to effect gene delivery, one chapter being dedicated to the new field of
RNA
interference (RNAi). This latter method may be successfully used in renal ischemia-reper-
fusion injury, trauma and transplantation, in the near future, gene therapy might also prove
to be a new strategy to target molecules involved in tissue damage and inflammation pro¬
cesses that underlie ARF. So far, gene transfer has been successfully applied in experimental
glomerulonephritis and interstitial fibrosis, and studies in larger animals are keenly awaited.
Also covered are issues related to transplantation, which is the therapy of choice in many end-
stage organ failures. Transfer of genes whose protein products have immunomodulatory
properties have proven beneficial in treating acute and chronic graft rejection, one of the
problems not satisfactorily solved by current anti-rejection drugs. Gene therapy thus may be¬
come a reality in clinical transplantation once its efficacy in larger animals has been demon¬
strated. Last but not least, a possible benefit of targeted gene therapy in renal cancer or HIV-
associated nephropathy is explored.
Covering a wide spectrum of topics, this publication provides a valuable overview of current
developments and issues.
Caver.
ШШгаветк
te tos», ÇhJnw«
artronsmers
regbtered
the appearance in the sky of a new
stať
which
reraâinèd
vfcíbfe
fear
21
nňftnUis
and then disappeared. The recent
identifleatìon
of the Crab NefouJs
m
the
Taurus
Const&DattQñ
sheds
sorine
light on tbe smgwaHc dlsappsannee
ef
the
supernova,
Experiments
¡în
gene
therapy dete
ßack
aver six
Acedes
to
Oswald
Aver/s pioneering studies with
prreuraacoćcał
transfbrmatfen
sbevstínjl·
that
sóm»
bacteria can
tato
aę naloęd
DNA, Nöw
it is
pírhjçs
Йвш
to see the impact of correcting
genetic
abBârrnalJôes
fcy means
sfa
géne
as treatment for many
dt$abiín¡p
or devastating diseases.
f!te!SAł*de
creaţi
^
|
| adam_txt |
Contents
Vii
Preface
Benigni,
Α.;
Remuzzi, G. (Bergamo)
1
Renal Diseases as Targets of Gene Therapy
Phillips,
В.;
Giannoukakis,
Ν.;
Trucco,
M.
(Pittsburgh, Pa.)
13
Nonviral Gene Delivery
Akita, H.; Harashima, H. (Sapporo/Saitama)
30
Retrovirus
Vectors
Lech, P.; Somia, N.V. (Minneapolis, Minn.)
47
Adenovirus Vectors for Renal-Targeted Gene Delivery
Appiedorn,
D.M.;
Seregin, S.;
Amalfitano,
A. (East Lansing, Mich.)
63
Adeno-Associated Virus Vectors: Versatile Tools for in vfwo Gene
Transfer
Zentilin, L.;
Giacca,
M.
(Trieste)
78
RNA
Interference in Research and Therapy of Renal Diseases
Rácz,
Z.;
Hamar,
P. (Budapest)
96
Gene Therapy for Acute Renal Failure
Torras,
J.;
Cruzado, J.M.; Herrero-Fresneda, I.; Grinyo,
J.M.
(Barcelona)
109
Chronic Deteriorating Renal Function and Renal Fibrosis
¡saka. Y.;
Такаћага,
S.;
Imai,
E. (Suita)
122
Ailograft Rejection: Acute and Chronic Studies
Tomasoni, S.; Remuzzi, G.;
Benigni,
A. (Bergamo)
135
Gene Therapy for Renal Cancer
Haviv, Y.S. (Jerusalem);
Curiei, D.T.
(Birmingham, Ala.)
151
HIV-Associated Nephropathy
Wyatt,
СМ.;
Rosenstiel, P.E.;
Klotman,
P.E. (New York, N.Y.)
162
Author
Index
163
Subject
Index
Contents
VI
159
Gene Therapy for Renal Diseases and Transplantation
Editors:
A. Benigni,
G. Remuzzi,
Bergamo
VIII + 168
p.,
15
fig.,
4
in color,
б
tab., hard cover,
2008.
ISBN
978-3-8055-8505-7
Initially conceived as a strategy to remedy inherited genetic disorders, gene therapy has been
successfully applied in the last decade to ameliorate the renal function compromised by pro¬
gressive renal diseases and to prevent kidney ailograft rejection in experimental animals.
In the present book, world-renowned experts are presenting new insights into viral and non-
viral systems used to effect gene delivery, one chapter being dedicated to the new field of
RNA
interference (RNAi). This latter method may be successfully used in renal ischemia-reper-
fusion injury, trauma and transplantation, in the near future, gene therapy might also prove
to be a new strategy to target molecules involved in tissue damage and inflammation pro¬
cesses that underlie ARF. So far, gene transfer has been successfully applied in experimental
glomerulonephritis and interstitial fibrosis, and studies in larger animals are keenly awaited.
Also covered are issues related to transplantation, which is the therapy of choice in many end-
stage organ failures. Transfer of genes whose protein products have immunomodulatory
properties have proven beneficial in treating acute and chronic graft rejection, one of the
problems not satisfactorily solved by current anti-rejection drugs. Gene therapy thus may be¬
come a reality in clinical transplantation once its efficacy in larger animals has been demon¬
strated. Last but not least, a possible benefit of targeted gene therapy in renal cancer or HIV-
associated nephropathy is explored.
Covering a wide spectrum of topics, this publication provides a valuable overview of current
developments and issues.
Caver.
ШШгаветк
te tos», ÇhJnw«
artronsmers
regbtered
the appearance in the sky of a 'new
stať
which
reraâinèd
vfcíbfe
fear
21
nňftnUis
and then disappeared. The recent
identifleatìon
of the Crab NefouJs
m
the
Taurus
Const&DattQñ
sheds
sorine
light on tbe smgwaHc dlsappsannee
ef
the
supernova,
Experiments
¡în
gene
therapy dete
ßack
aver six
Acedes
to
Oswald
Aver/s pioneering studies with
prreuraacoćcał
transfbrmatfen
sbevstínjl·
that
sóm»
bacteria can
tato
aę naloęd
DNA, Nöw
it is
pírhjçs
Йвш
to see the impact of correcting
genetic
abBârrnalJôes
fcy means
sfa
géne
as treatment for many
dt$abiín¡p
or devastating diseases.
f!te!SAł*de
creaţi
^ |
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| genre | (DE-588)4143413-4 Aufsatzsammlung gnd-content |
| genre_facet | Aufsatzsammlung |
| id | DE-604.BV023324574 |
| illustrated | Illustrated |
| index_date | 2024-07-02T20:55:05Z |
| indexdate | 2024-07-09T21:15:54Z |
| institution | BVB |
| isbn | 9783805585057 3805585055 |
| language | English |
| lccn | 2008006529 |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-016508616 |
| oclc_num | 239369716 |
| open_access_boolean | |
| owner | DE-12 DE-355 DE-BY-UBR |
| owner_facet | DE-12 DE-355 DE-BY-UBR |
| physical | VIII, 167 S. Ill., graph. Darst. |
| publishDate | 2008 |
| publishDateSearch | 2008 |
| publishDateSort | 2008 |
| publisher | Karger |
| record_format | marc |
| series | Contributions to nephrology |
| series2 | Contributions to nephrology |
| spelling | Gene therapy for renal diseases and transplantation 6 tables vol. ed.: Ariela Benigni ... Basel [u.a.] Karger 2008 VIII, 167 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Contributions to nephrology 159 Includes bibliographical references and indexes Gene Therapy Gene therapy Graft Rejection - therapy Graft rejection - Prevention Kidney Diseases - therapy Kidney Transplantation Kidneys - Diseases - Gene therapy Kidneys - Transplantation - Genetic aspects Kidneys Diseases Gene therapy Kidneys Transplantation Genetic aspects Graft rejection Prevention Kidney Diseases therapy Graft Rejection therapy Nierentransplantation (DE-588)4042284-7 gnd rswk-swf Transplantatabstoßung (DE-588)4137807-6 gnd rswk-swf Niere (DE-588)4042270-7 gnd rswk-swf Gentherapie (DE-588)4296957-8 gnd rswk-swf Nierenkrankheit (DE-588)4075399-2 gnd rswk-swf Gentransfer (DE-588)4194102-0 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Nierenkrankheit (DE-588)4075399-2 s Gentherapie (DE-588)4296957-8 s DE-604 Niere (DE-588)4042270-7 s Gentransfer (DE-588)4194102-0 s Nierentransplantation (DE-588)4042284-7 s Transplantatabstoßung (DE-588)4137807-6 s Benigni, Ariela Sonstige oth Contributions to nephrology 159 (DE-604)BV000000413 159 Digitalisierung UB Regensburg application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=016508616&sequence=000004&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis Digitalisierung UB Regensburg application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=016508616&sequence=000005&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA Klappentext |
| spellingShingle | Gene therapy for renal diseases and transplantation 6 tables Contributions to nephrology Gene Therapy Gene therapy Graft Rejection - therapy Graft rejection - Prevention Kidney Diseases - therapy Kidney Transplantation Kidneys - Diseases - Gene therapy Kidneys - Transplantation - Genetic aspects Kidneys Diseases Gene therapy Kidneys Transplantation Genetic aspects Graft rejection Prevention Kidney Diseases therapy Graft Rejection therapy Nierentransplantation (DE-588)4042284-7 gnd Transplantatabstoßung (DE-588)4137807-6 gnd Niere (DE-588)4042270-7 gnd Gentherapie (DE-588)4296957-8 gnd Nierenkrankheit (DE-588)4075399-2 gnd Gentransfer (DE-588)4194102-0 gnd |
| subject_GND | (DE-588)4042284-7 (DE-588)4137807-6 (DE-588)4042270-7 (DE-588)4296957-8 (DE-588)4075399-2 (DE-588)4194102-0 (DE-588)4143413-4 |
| title | Gene therapy for renal diseases and transplantation 6 tables |
| title_auth | Gene therapy for renal diseases and transplantation 6 tables |
| title_exact_search | Gene therapy for renal diseases and transplantation 6 tables |
| title_exact_search_txtP | Gene therapy for renal diseases and transplantation 6 tables |
| title_full | Gene therapy for renal diseases and transplantation 6 tables vol. ed.: Ariela Benigni ... |
| title_fullStr | Gene therapy for renal diseases and transplantation 6 tables vol. ed.: Ariela Benigni ... |
| title_full_unstemmed | Gene therapy for renal diseases and transplantation 6 tables vol. ed.: Ariela Benigni ... |
| title_short | Gene therapy for renal diseases and transplantation |
| title_sort | gene therapy for renal diseases and transplantation 6 tables |
| title_sub | 6 tables |
| topic | Gene Therapy Gene therapy Graft Rejection - therapy Graft rejection - Prevention Kidney Diseases - therapy Kidney Transplantation Kidneys - Diseases - Gene therapy Kidneys - Transplantation - Genetic aspects Kidneys Diseases Gene therapy Kidneys Transplantation Genetic aspects Graft rejection Prevention Kidney Diseases therapy Graft Rejection therapy Nierentransplantation (DE-588)4042284-7 gnd Transplantatabstoßung (DE-588)4137807-6 gnd Niere (DE-588)4042270-7 gnd Gentherapie (DE-588)4296957-8 gnd Nierenkrankheit (DE-588)4075399-2 gnd Gentransfer (DE-588)4194102-0 gnd |
| topic_facet | Gene Therapy Gene therapy Graft Rejection - therapy Graft rejection - Prevention Kidney Diseases - therapy Kidney Transplantation Kidneys - Diseases - Gene therapy Kidneys - Transplantation - Genetic aspects Kidneys Diseases Gene therapy Kidneys Transplantation Genetic aspects Graft rejection Prevention Kidney Diseases therapy Graft Rejection therapy Nierentransplantation Transplantatabstoßung Niere Gentherapie Nierenkrankheit Gentransfer Aufsatzsammlung |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=016508616&sequence=000004&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=016508616&sequence=000005&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA |
| volume_link | (DE-604)BV000000413 |
| work_keys_str_mv | AT benigniariela genetherapyforrenaldiseasesandtransplantation6tables |