Scale-up of liposome manufacturing: combining high pressure liposome extrusion with drying technologies
Gespeichert in:
| 1. Verfasser: | |
|---|---|
| Format: | Abschlussarbeit Buch |
| Sprache: | English |
| Veröffentlicht: |
Göttingen
Cuvillier
2008
|
| Ausgabe: | 1. Aufl. |
| Schlagworte: | |
| Online-Zugang: | Volltext https://nbn-resolving.org/urn:nbn:de:bvb:19-84870 Inhaltsverzeichnis |
| Beschreibung: | 220 S. graph. Darst. |
| ISBN: | 9783867275439 3867275432 |
Internformat
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| 245 | 1 | 0 | |a Scale-up of liposome manufacturing |b combining high pressure liposome extrusion with drying technologies |c Michael Wiggenhorn |
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Datensatz im Suchindex
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|---|---|
| adam_text | * * * * BIBLIOGRAFISCHE INFORMATIONEN HTTP://D-NB.INFO/987988190
DIGITALISIERT DURCH 5. REFERENCES 68 CHAPTER 3 SPRAY FREEZE-DRYING OF
LIPOSOME PACLITAXEL FORMU/ATIONS 1. INTRODUCTION 44 2. MATERIAL AND
METHODS 45 2.1 UPOSOME PREPARATION 45 2.2 SPRAY-FREEZING METHODS 45 2.3
FREEZE-DRYING METHOD 46 2.4 FREEZE-DRYING VELOCITY 47 2.5 ANALYSIS OF
PELLET MORPHOLOGY 47 3. RESULTS AND DISCUSSION 48 3.1 PARTICLE FORMATION
PROCESSES 48 3.2 DRYING VELOCITY 49 3.3 PARTICLE YIELD AND RESIDUAL
SOLVENT CONTENT 49 3.4 PARTIDE SIZE DISTRIBUTION 50 3.5 RESIDUAL
MOISTURE 51 3.6 PARTIDE MORPHOLOGY 52 3.7 UPOSOME CHARACTERIZATION 53
3.8 UPID AND PADITAXEL RECOVERY 54 4. CONCLUSIONS 55 5. REFERENCES 56
CHAPTER 4 DEVELOPMENT OF A PERCOLATIVE VACUUM-DRYING PROCESS 1.
INTRODUCTION 59 2. MATERIAL AND METHODS 60 2.1 UPOSOME PREPARATION 60
2.2 FLUORESCENCE SPECTROSCOPY 60 2.3 PERCOLAUEVE-DRYING METHOD ..61 3.
RESULTS AND DISCUSSION 62 3.1 THE PERCOLAOEVE DRYING CONCEPT 62 3.2
RESIDUAL MOISTURE 64 3.3 PARTIDE MORPHOLOGY 65 3.4 UPOSOME PROPERTIES
AND DRUG LOADING 6S 3.5 UPID RECOVERY 66 4. CONCLUSIONS 67 5. REFERENCES
90 CHAPTER 5 EVALUATION OF SPRAY-DRYING AS A STABILIZING TECHNIQUE FOR
LIPOSOMES 1. INTRODUCTION 70 2. MATERIAL AND METHODS 71 2.1 UPOSOME
FORMATION 71 2.2 SPRAY-DRYING METHOD WITH BUECHI MINI SPRAY-DRYER 71 2.3
SPRAY-DRYING METHOD WITH A NIRO SD-MICRO 72 2.4 VACUUM-DRYING 73 2.5
ANALYSIS OF PARTIDE MORPHOLOGY 73 2.6 VISCOSITY MEASUREMENTS 74 2.7 UGHT
OBSCURATION 74 2.8 ZETA-POTENTIAL 74 3. RESULTS AND DISCUSSION 75 3.1
FEASIBILITY STUDY OF UPOSOME SPRAY-DRYING 75 3.1.1 PARTIDE MORPHOLOGY 75
3.1.2 PRODUCT TEMPERATURE DURING THE PROCESS 75 3.1.3 PARTICLE SIZE
DISTRIBUTION 77 3.1.4 RESIDUAL MOISTURE CONTENT 78 3.1.5 PARTIDE YIELD
79 3.1.6 UPOSOME RECOVERY 80 3.1.6.1 UPOSOME SIZE AND POLYDISPERSITY 80
3.1.6.2 UPOSOME ZETA-POTENTIAL 83 3.1.7 PHYSICO-CHEMICAL
CHARACTERIZATION 83 3.1.8 UPID RECOVERY 85 3.2 SPRAY-DRYING OF PADITAXEL
FORMULATIONS 85 3.2.1 PARTIDE PROPERTIES 86 3.2.2 UPOSOME RECOVERY 87
3.2.3 PADITAXEL RECOVERY 87 3.2.4 PARTIDE CONTAMINATION 88 4.
CONCLUSIONS 89 * * * * * * * *
|
| adam_txt |
* * * * BIBLIOGRAFISCHE INFORMATIONEN HTTP://D-NB.INFO/987988190
DIGITALISIERT DURCH 5. REFERENCES 68 CHAPTER 3 SPRAY FREEZE-DRYING OF
LIPOSOME PACLITAXEL FORMU/ATIONS 1. INTRODUCTION 44 2. MATERIAL AND
METHODS 45 2.1 UPOSOME PREPARATION 45 2.2 SPRAY-FREEZING METHODS 45 2.3
FREEZE-DRYING METHOD 46 2.4 FREEZE-DRYING VELOCITY 47 2.5 ANALYSIS OF
PELLET MORPHOLOGY 47 3. RESULTS AND DISCUSSION 48 3.1 PARTICLE FORMATION
PROCESSES 48 3.2 DRYING VELOCITY 49 3.3 PARTICLE YIELD AND RESIDUAL
SOLVENT CONTENT 49 3.4 PARTIDE SIZE DISTRIBUTION 50 3.5 RESIDUAL
MOISTURE 51 3.6 PARTIDE MORPHOLOGY 52 3.7 UPOSOME CHARACTERIZATION 53
3.8 UPID AND PADITAXEL RECOVERY 54 4. CONCLUSIONS 55 5. REFERENCES 56
CHAPTER 4 DEVELOPMENT OF A PERCOLATIVE VACUUM-DRYING PROCESS 1.
INTRODUCTION 59 2. MATERIAL AND METHODS 60 2.1 UPOSOME PREPARATION 60
2.2 FLUORESCENCE SPECTROSCOPY 60 2.3 PERCOLAUEVE-DRYING METHOD .61 3.
RESULTS AND DISCUSSION 62 3.1 THE PERCOLAOEVE DRYING CONCEPT 62 3.2
RESIDUAL MOISTURE 64 3.3 PARTIDE MORPHOLOGY 65 3.4 UPOSOME PROPERTIES
AND DRUG LOADING 6S 3.5 UPID RECOVERY 66 4. CONCLUSIONS 67 5. REFERENCES
90 CHAPTER 5 EVALUATION OF SPRAY-DRYING AS A STABILIZING TECHNIQUE FOR
LIPOSOMES 1. INTRODUCTION 70 2. MATERIAL AND METHODS 71 2.1 UPOSOME
FORMATION 71 2.2 SPRAY-DRYING METHOD WITH BUECHI MINI SPRAY-DRYER 71 2.3
SPRAY-DRYING METHOD WITH A NIRO SD-MICRO 72 2.4 VACUUM-DRYING 73 2.5
ANALYSIS OF PARTIDE MORPHOLOGY 73 2.6 VISCOSITY MEASUREMENTS 74 2.7 UGHT
OBSCURATION 74 2.8 ZETA-POTENTIAL 74 3. RESULTS AND DISCUSSION 75 3.1
FEASIBILITY STUDY OF UPOSOME SPRAY-DRYING 75 3.1.1 PARTIDE MORPHOLOGY 75
3.1.2 PRODUCT TEMPERATURE DURING THE PROCESS 75 3.1.3 PARTICLE SIZE
DISTRIBUTION 77 3.1.4 RESIDUAL MOISTURE CONTENT 78 3.1.5 PARTIDE YIELD
79 3.1.6 UPOSOME RECOVERY 80 3.1.6.1 UPOSOME SIZE AND POLYDISPERSITY 80
3.1.6.2 UPOSOME ZETA-POTENTIAL 83 3.1.7 PHYSICO-CHEMICAL
CHARACTERIZATION 83 3.1.8 UPID RECOVERY 85 3.2 SPRAY-DRYING OF PADITAXEL
FORMULATIONS 85 3.2.1 PARTIDE PROPERTIES 86 3.2.2 UPOSOME RECOVERY 87
3.2.3 PADITAXEL RECOVERY 87 3.2.4 PARTIDE CONTAMINATION 88 4.
CONCLUSIONS 89 * * * * * * * * |
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| author | Wiggenhorn, Michael 1977- |
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| dewey-full | 615.19 |
| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 615 - Pharmacology and therapeutics |
| dewey-raw | 615.19 |
| dewey-search | 615.19 |
| dewey-sort | 3615.19 |
| dewey-tens | 610 - Medicine and health |
| discipline | Medizin |
| discipline_str_mv | Medizin |
| edition | 1. Aufl. |
| format | Thesis Book |
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| spelling | Wiggenhorn, Michael 1977- Verfasser (DE-588)135591007 aut Scale-up of liposome manufacturing combining high pressure liposome extrusion with drying technologies Michael Wiggenhorn 1. Aufl. Göttingen Cuvillier 2008 220 S. graph. Darst. txt rdacontent n rdamedia nc rdacarrier Zugl.: München, Univ., Diss., 2007 Trocknung (DE-588)4124329-8 gnd rswk-swf Arzneistoffträger (DE-588)4278196-6 gnd rswk-swf Pharmazeutische Technologie (DE-588)4045699-7 gnd rswk-swf Liposom (DE-588)4122262-3 gnd rswk-swf (DE-588)4113937-9 Hochschulschrift gnd-content Liposom (DE-588)4122262-3 s Arzneistoffträger (DE-588)4278196-6 s Trocknung (DE-588)4124329-8 s Pharmazeutische Technologie (DE-588)4045699-7 s DE-604 Erscheint auch als Online-Ausgabe urn:nbn:de:bvb:19-84870 http://edoc.ub.uni-muenchen.de/8487/ Verlag kostenfrei Volltext https://nbn-resolving.org/urn:nbn:de:bvb:19-84870 Resolving-System DNB Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=016497202&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Wiggenhorn, Michael 1977- Scale-up of liposome manufacturing combining high pressure liposome extrusion with drying technologies Trocknung (DE-588)4124329-8 gnd Arzneistoffträger (DE-588)4278196-6 gnd Pharmazeutische Technologie (DE-588)4045699-7 gnd Liposom (DE-588)4122262-3 gnd |
| subject_GND | (DE-588)4124329-8 (DE-588)4278196-6 (DE-588)4045699-7 (DE-588)4122262-3 (DE-588)4113937-9 |
| title | Scale-up of liposome manufacturing combining high pressure liposome extrusion with drying technologies |
| title_auth | Scale-up of liposome manufacturing combining high pressure liposome extrusion with drying technologies |
| title_exact_search | Scale-up of liposome manufacturing combining high pressure liposome extrusion with drying technologies |
| title_exact_search_txtP | Scale-up of liposome manufacturing combining high pressure liposome extrusion with drying technologies |
| title_full | Scale-up of liposome manufacturing combining high pressure liposome extrusion with drying technologies Michael Wiggenhorn |
| title_fullStr | Scale-up of liposome manufacturing combining high pressure liposome extrusion with drying technologies Michael Wiggenhorn |
| title_full_unstemmed | Scale-up of liposome manufacturing combining high pressure liposome extrusion with drying technologies Michael Wiggenhorn |
| title_short | Scale-up of liposome manufacturing |
| title_sort | scale up of liposome manufacturing combining high pressure liposome extrusion with drying technologies |
| title_sub | combining high pressure liposome extrusion with drying technologies |
| topic | Trocknung (DE-588)4124329-8 gnd Arzneistoffträger (DE-588)4278196-6 gnd Pharmazeutische Technologie (DE-588)4045699-7 gnd Liposom (DE-588)4122262-3 gnd |
| topic_facet | Trocknung Arzneistoffträger Pharmazeutische Technologie Liposom Hochschulschrift |
| url | http://edoc.ub.uni-muenchen.de/8487/ https://nbn-resolving.org/urn:nbn:de:bvb:19-84870 http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=016497202&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
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