Reading the story in DNA: a beginner's guide to molecular evolution
Gespeichert in:
| Späterer Titel: | Bromham, Lindell An introduction to molecular evolution and phylogenetics |
|---|---|
| 1. Verfasser: | |
| Format: | Buch |
| Sprache: | English |
| Veröffentlicht: |
Oxford [u.a.]
Oxford Univ. Press
2008
|
| Ausgabe: | 1. publ. |
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis Klappentext |
| Beschreibung: | XIII, 368 S. zahlr. Ill., graph. Darst. |
| ISBN: | 9780199290918 0199290911 |
Internformat
MARC
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| 100 | 1 | |a Bromham, Lindell |e Verfasser |0 (DE-588)1186181311 |4 aut | |
| 245 | 1 | 0 | |a Reading the story in DNA |b a beginner's guide to molecular evolution |c Lindell Bromham |
| 250 | |a 1. publ. | ||
| 264 | 1 | |a Oxford [u.a.] |b Oxford Univ. Press |c 2008 | |
| 300 | |a XIII, 368 S. |b zahlr. Ill., graph. Darst. | ||
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| 650 | 4 | |a DNA | |
| 650 | 4 | |a Evolution, Molecular | |
| 650 | 4 | |a Evolutionary genetics | |
| 650 | 4 | |a Molecular evolution | |
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| 785 | 0 | 0 | |i Fortgesetzt durch |a Bromham, Lindell |t An introduction to molecular evolution and phylogenetics |d Oxford : Oxford University Press, [2016] |z 978-0-19-873636-3 |w (DE-604)BV043259414 |
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Datensatz im Suchindex
| _version_ | 1804137570214346752 |
|---|---|
| adam_text | Contents
The
story in
DNA
Or:
what kind of information
can I get from
DNA ?
pagel
The
«оту ¿Ь
__
ВЩйВ
^Ч
The mystery of the Chilean blob
2
TB1.1 GenBank
3
CS1.1 Solving the mystery of the Chilean blob
5
Individuals, families, and populations
8
TB1.2
DNA
sequencing
10
Uncovering the evolutionary past
14
CS1.2
DNA
surveillance
15
Evolution of animal body plans
21
About this book
23
φ
Conclusions
29
О
Further information
29
The immortal germline
Or: how do
Iget DNA
samples?
page
30
Unity of life
31
Principles of heredity
33
Discovery of the gene
36
Structure of
DNA 38
TB2.1 Hershey-Chase blender experiment
39
TB2.2
DNA
structure
41
TB2.3 Genetic code
47
Ubiquity of
DNA 50
TB2.4
DNA
extraction
51
CS2.1 On the origin of faeces
53
CS2.2 More
moa
56
φ
Conclusions
О
Further information
59
61
We are all mutants
Or: how do I identify individuals?
page
62
Mutants
CS3.1 Viruses within
TB3.1
Genenames
Repeat sequences
TB3.2
Biobanking
CS3.2 A modem Icelandic saga
Point mutations
TB3.3 SNPs
TB3.4 BLAST
Mutation rate
φ
Conclusions
О
Further information
Endless copies
Or: how do I amplify
DNA ?
page
101
Blame your father
Template reproduction
TB4.1
DNA
replication
TB4.2
DNA
amplification
Polymerase chain reaction (PCR)
TB4.3 Primer design
CS4.1 Glorious mud
63
69
73
75
80
83
86
90
93
95
99
100
102
104
107
111
113
115
117
XU
Contents
Faithful but not perfect
History in the genome
TB4.4 Copy errors reveal history
CS4.2 Peopling the Pacific
φ
Conclusions
О
Further information
121
124
126
127
135
136
Descent with modification
Or: how do I detect natural selection?
page
137
Variation
Substitution
The power of selection
CS5.1 Sweet and sour
TB5.1 Fitness
Genetic drift
TB5.2 Neutral theory
TB5.3 Population size
Patterns of substitution
TB5.4 Detecting selection
CS5.2 Time flies
Are humans still evolving?
φ
Conclusions
О
Further information
Origin of species
Or: how do I align
DNA
sequences?
page
185
Naming names
TB6.1 Taxonomy
Genetic divergence
CS6.1 Barcoding nematodes
TB6.2 What is a species?
Homology: shared by descent
Sequence alignment
Changing, adding, and taking away
138
140
143
146
155
157
162
168
171
175
177
180
183
184
,
186
187
191
193
196
205
207
209
TB6.3 Sequence alignment
The fate of the thylacine
CS6.2 Keeping the pieces
TB6.4 Cloning and conservation
φ
Conclusions
О
Further information
211
215
217
220
222
223
Tree of life
Or: how do I construct a phytogeny?
page
224
Phylogeny reflects history
225
Life as a tree
227
CS7.1 Up the river
233
CS7.2 Non-tree-like flower
236
Substitutions reveal relationships
239
Trees that reflect similarities
249
TB7.1 Distance methods
253
Trees as evolutionary paths
257
TB7.2 Maximum likelihood
260
Statistical inference of phylogeny
264
TB7.3 Bayesian phylogenetics
265
How good is my tree?
270
TB7.4 Bootstrapping
272
Which phylogenetic method should
1
choose?
276
φ
Conclusions
277
О
Further information
278
Tempo and mode
Or: how do I estimate molecular dates?
page
279
An odd fish
TB8.1 Estimating branch lengths
CS8.1 Same but different
Pace of evolutionary change
Molecular dating
TB8.2 Calibration
Contents
Kill
Accuracy and precision
310
Variation in the rate of molecular evolution
315
TB8.3 Detecting rate variation
317
CS8.2 Molecular detective
321
TB8.4 Molecular dating
327
φ
Conclusions
330
О
Further information
330
You are a scientist
Or: what do I do now?
page
331
Appendix I The genetic code
Appendix
Π
Sequences used in this book
Appendix III The geological timescale
Glossary
Bibliography
Index
334
335
337
338
356
360
•
The first text to make the use of molecular data in
whole organism biology truly accessible to students.
•
Engaging yet highly informative writing style
captures the author s genuine and infectious passion
for the subject.
•
Blends clear, straightforward explanations with
cutting-edge case studies: there is no sacrifice of
content for the sake of accessibility.
•
Unique combination of text, technical information,
and case studies enables flexible use. to meet the
particular needs of each reader.
The world is full of
DNA.
The salad in your sandwich, the
pollen in the air, even the dirt on your shoes contains
DNA
from which a vast amount of information can be
gained, including the identification of individuals and
species, the structure and distribution of populations,
the origins of lineages and the pace and mechanisms of
evolutionary change.
Reading the story in
DNA
is a beginner s guide to
molecular evolution, and is the perfect starting point on
the journey to an understanding of the way molecular
data is used in modern biology.
The use of bioinformatic analyses has revolutionized
biology, and there are now few areas of evolution and
ecology that remain untouched by molecular data.
Today s biology students and researchers need to be
familiar with the application of molecular data to
answer evolutionary questions. But the most pressing
question is usually: Where do
!
start?! This book is
the answer.
|
| adam_txt |
Contents
The
story in
DNA
Or:
what kind of information
can I get from
DNA ?
pagel
The
«оту ¿Ь
_
ВЩйВ
^Ч
The mystery of the Chilean blob
2
TB1.1 GenBank
3
CS1.1 Solving the mystery of the Chilean blob
5
Individuals, families, and populations
8
TB1.2
DNA
sequencing
10
Uncovering the evolutionary past
14
CS1.2
DNA
surveillance
15
Evolution of animal body plans
21
About this book
23
φ
Conclusions
29
О
Further information
29
The immortal germline
Or: how do
Iget DNA
samples?
page
30
Unity of life
31
Principles of heredity
33
Discovery of the gene
36
Structure of
DNA 38
TB2.1 Hershey-Chase blender experiment
39
TB2.2
DNA
structure
41
TB2.3 Genetic code
47
Ubiquity of
DNA 50
TB2.4
DNA
extraction
51
CS2.1 On the origin of faeces
53
CS2.2 More
moa
56
φ
Conclusions
О
Further information
59
61
We are all mutants
Or: how do I identify individuals?
page
62
Mutants
CS3.1 Viruses within
TB3.1
Genenames
Repeat sequences
TB3.2
Biobanking
CS3.2 A modem Icelandic saga
Point mutations
TB3.3 SNPs
TB3.4 BLAST
Mutation rate
φ
Conclusions
О
Further information
Endless copies
Or: how do I amplify
DNA ?
page
101
Blame your father
Template reproduction
TB4.1
DNA
replication
TB4.2
DNA
amplification
Polymerase chain reaction (PCR)
TB4.3 Primer design
CS4.1 Glorious mud
63
69
73
75
80
83
86
90
93
95
99
100
102
104
107
111
113
115
117
XU
Contents
Faithful but not perfect
History in the genome
TB4.4 Copy errors reveal history
CS4.2 Peopling the Pacific
φ
Conclusions
О
Further information
121
124
126
127
135
136
Descent with modification
Or: how do I detect natural selection?
page
137
Variation
Substitution
The power of selection
CS5.1 Sweet and sour
TB5.1 Fitness
Genetic drift
TB5.2 Neutral theory
TB5.3 Population size
Patterns of substitution
TB5.4 Detecting selection
CS5.2 Time flies
Are humans still evolving?
φ
Conclusions
О
Further information
Origin of species
Or: how do I align
DNA
sequences?
page
185
Naming names
TB6.1 Taxonomy
Genetic divergence
CS6.1 Barcoding nematodes
TB6.2 What is a species?
Homology: shared by descent
Sequence alignment
Changing, adding, and taking away
138
140
143
146
155
157
162
168
171
175
177
180
183
184
,
186
187
191
193
196
205
207
209
TB6.3 Sequence alignment
The fate of the thylacine
CS6.2 Keeping the pieces
TB6.4 Cloning and conservation
φ
Conclusions
О
Further information
211
215
217
220
222
223
Tree of life
Or: how do I construct a phytogeny?
page
224
Phylogeny reflects history
225
Life as a tree
227
CS7.1 Up the river
233
CS7.2 Non-tree-like flower
236
Substitutions reveal relationships
239
Trees that reflect similarities
249
TB7.1 Distance methods
253
Trees as evolutionary paths
257
TB7.2 Maximum likelihood
260
Statistical inference of phylogeny
264
TB7.3 Bayesian phylogenetics
265
How good is my tree?
270
TB7.4 Bootstrapping
272
Which phylogenetic method should
1
choose?
276
φ
Conclusions
277
О
Further information
278
Tempo and mode
Or: how do I estimate molecular dates?
page
279
An odd fish
TB8.1 Estimating branch lengths
CS8.1 Same but different
Pace of evolutionary change
Molecular dating
TB8.2 Calibration
Contents
Kill
Accuracy and precision
310
Variation in the rate of molecular evolution
315
TB8.3 Detecting rate variation
317
CS8.2 Molecular detective
321
TB8.4 Molecular dating
327
φ
Conclusions
330
О
Further information
330
You are a scientist
Or: what do I do now?
page
331
Appendix I The genetic code
Appendix
Π
Sequences used in this book
Appendix III The geological timescale
Glossary
Bibliography
Index
334
335
337
338
356
360
•
The first text to make the use of molecular data in
whole organism biology truly accessible to students.
•
Engaging yet highly informative writing style
captures the author's genuine and infectious passion
for the subject.
•
Blends clear, straightforward explanations with
cutting-edge case studies: there is no sacrifice of
content for the sake of accessibility.
•
Unique combination of text, technical information,
and case studies enables flexible use. to meet the
particular needs of each reader.
The world is full of
DNA.
The salad in your sandwich, the
pollen in the air, even the dirt on your shoes contains
DNA
from which a vast amount of information can be
gained, including the identification of individuals and
species, the structure and distribution of populations,
the origins of lineages and the pace and mechanisms of
evolutionary change.
Reading the story in
DNA
is a beginner's guide to
molecular evolution, and is the perfect starting point on
the journey to an understanding of the way molecular
data is used in modern biology.
The use of 'bioinformatic' analyses has revolutionized
biology, and there are now few areas of evolution and
ecology that remain untouched by molecular data.
Today's biology students and researchers need to be
familiar with the application of molecular data to
answer evolutionary questions. But the most pressing
question is usually:"Where do
!
start?!"This book is
the answer. |
| any_adam_object | 1 |
| any_adam_object_boolean | 1 |
| author | Bromham, Lindell |
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| dewey-full | 572.838 572.8/6 |
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| dewey-ones | 572 - Biochemistry |
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| discipline | Biologie |
| discipline_str_mv | Biologie |
| edition | 1. publ. |
| format | Book |
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| genre | (DE-588)4123623-3 Lehrbuch gnd-content |
| genre_facet | Lehrbuch |
| id | DE-604.BV023261363 |
| illustrated | Illustrated |
| index_date | 2024-07-02T20:32:12Z |
| indexdate | 2024-07-09T21:14:23Z |
| institution | BVB |
| isbn | 9780199290918 0199290911 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-016446562 |
| oclc_num | 183146744 |
| open_access_boolean | |
| owner | DE-M49 DE-BY-TUM DE-19 DE-BY-UBM DE-29 DE-11 DE-355 DE-BY-UBR DE-188 |
| owner_facet | DE-M49 DE-BY-TUM DE-19 DE-BY-UBM DE-29 DE-11 DE-355 DE-BY-UBR DE-188 |
| physical | XIII, 368 S. zahlr. Ill., graph. Darst. |
| publishDate | 2008 |
| publishDateSearch | 2008 |
| publishDateSort | 2008 |
| publisher | Oxford Univ. Press |
| record_format | marc |
| spelling | Bromham, Lindell Verfasser (DE-588)1186181311 aut Reading the story in DNA a beginner's guide to molecular evolution Lindell Bromham 1. publ. Oxford [u.a.] Oxford Univ. Press 2008 XIII, 368 S. zahlr. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier DNA Evolution, Molecular Evolutionary genetics Molecular evolution Evolutionsbiologie (DE-588)4153283-1 gnd rswk-swf Molekulargenetik (DE-588)4039987-4 gnd rswk-swf Molekulare Evolution (DE-588)4812902-1 gnd rswk-swf Evolution (DE-588)4071050-6 gnd rswk-swf Molekularbiologie (DE-588)4039983-7 gnd rswk-swf (DE-588)4123623-3 Lehrbuch gnd-content Molekularbiologie (DE-588)4039983-7 s Evolutionsbiologie (DE-588)4153283-1 s DE-604 Molekulare Evolution (DE-588)4812902-1 s Molekulargenetik (DE-588)4039987-4 s Evolution (DE-588)4071050-6 s DE-188 Fortgesetzt durch Bromham, Lindell An introduction to molecular evolution and phylogenetics Oxford : Oxford University Press, [2016] 978-0-19-873636-3 (DE-604)BV043259414 Digitalisierung UB Regensburg application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=016446562&sequence=000003&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis Digitalisierung UB Regensburg application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=016446562&sequence=000004&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA Klappentext |
| spellingShingle | Bromham, Lindell Reading the story in DNA a beginner's guide to molecular evolution DNA Evolution, Molecular Evolutionary genetics Molecular evolution Evolutionsbiologie (DE-588)4153283-1 gnd Molekulargenetik (DE-588)4039987-4 gnd Molekulare Evolution (DE-588)4812902-1 gnd Evolution (DE-588)4071050-6 gnd Molekularbiologie (DE-588)4039983-7 gnd |
| subject_GND | (DE-588)4153283-1 (DE-588)4039987-4 (DE-588)4812902-1 (DE-588)4071050-6 (DE-588)4039983-7 (DE-588)4123623-3 |
| title | Reading the story in DNA a beginner's guide to molecular evolution |
| title_auth | Reading the story in DNA a beginner's guide to molecular evolution |
| title_exact_search | Reading the story in DNA a beginner's guide to molecular evolution |
| title_exact_search_txtP | Reading the story in DNA a beginner's guide to molecular evolution |
| title_full | Reading the story in DNA a beginner's guide to molecular evolution Lindell Bromham |
| title_fullStr | Reading the story in DNA a beginner's guide to molecular evolution Lindell Bromham |
| title_full_unstemmed | Reading the story in DNA a beginner's guide to molecular evolution Lindell Bromham |
| title_new | Bromham, Lindell An introduction to molecular evolution and phylogenetics |
| title_short | Reading the story in DNA |
| title_sort | reading the story in dna a beginner s guide to molecular evolution |
| title_sub | a beginner's guide to molecular evolution |
| topic | DNA Evolution, Molecular Evolutionary genetics Molecular evolution Evolutionsbiologie (DE-588)4153283-1 gnd Molekulargenetik (DE-588)4039987-4 gnd Molekulare Evolution (DE-588)4812902-1 gnd Evolution (DE-588)4071050-6 gnd Molekularbiologie (DE-588)4039983-7 gnd |
| topic_facet | DNA Evolution, Molecular Evolutionary genetics Molecular evolution Evolutionsbiologie Molekulargenetik Molekulare Evolution Evolution Molekularbiologie Lehrbuch |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=016446562&sequence=000003&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=016446562&sequence=000004&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA |
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