Pharmacogenomics in drug discovery and development:
Gespeichert in:
| 1. Verfasser: | |
|---|---|
| Format: | Buch |
| Sprache: | English |
| Veröffentlicht: |
Totowa, NJ [u.a.]
Humana Press
2008
|
| Schriftenreihe: | Methods in molecular biology
448 |
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | XIII, 487 S. Ill., graph. Darst. |
| ISBN: | 1588298876 9781588298874 9781597452052 |
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| 300 | |a XIII, 487 S. |b Ill., graph. Darst. | ||
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| 650 | 7 | |a Pharmacodynamie |2 ram | |
| 650 | 7 | |a Pharmacogénétique |2 ram | |
| 650 | 4 | |a Biotransformation |x genetics | |
| 650 | 4 | |a Drug Design | |
| 650 | 4 | |a Drug development | |
| 650 | 4 | |a Drugs |x Effectiveness | |
| 650 | 4 | |a Pharmacogenetics |x methods | |
| 650 | 4 | |a Pharmacogenomics | |
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| 650 | 4 | |a Pharmacokinetics | |
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Datensatz im Suchindex
| _version_ | 1804137554819153920 |
|---|---|
| adam_text | Contents
Chapter 1 The Integration of Personalized and Systems Medicine:
Bioinformatics Support for Pharmacogenomics
and Drug Discovery 1
Qing Yan
Chapter 2 Applications of Microarrays and Biochips
in Pharmacogenomics 21
Gary Hardiman
Chapter 3 Confounding in Genetic Association Studies
and Its Solutions 31
Donglei Hu and Elad Ziv
Chapter 4 Pharmacogenetics of Membrane Transporters: A Review
of Current Approaches 41
Tristan M. Sissung, Erin R. Gardner, Rui Gao,
and William D. Figg
Chapter 5 Pharmacogenomics of Drug-Metabolizing
Enzymes and Drug Transporters in Chemotherapy 63
Tessa M. Bosch
Chapter 6 Pharmacogenomics of G Protein-Coupled Receptor
Signaling: Insights from Health and Disease 77
Miles D. Thompson, David E. C. Cole, and Pedro A. Jose
Chapter 7 G Protein-Coupled Receptors Disrupted in Human
Genetic Disease 109
Miles D. Thompson, Maire E. Percy, W. Mclntyre Burnham,
and David E. C. Cole
ix
x Contents
Chapter 8 G Protein-Coupled Receptor Pharmacogenetics 139
Miles D. Thompson, Katherine A. Siminoivitch,
and David E. C. Cole
Chapter 9 Epigenetic Alterations of the Dopaminergic System
in Major Psychiatric Disorders 187
Hamid Mostafavi Abdolmaleky, Cassandra L. Smith,
Jin-Rong Zhou, and Sam Thiagalingam
Chapter 10 Pharmacogenomics in Alzheimer s Disease 213
Ramon Cacabelos
Chapter 11 Pharmacogenetics of Asthma 359
Gregory A. Hawkins and Stephen P. Peters
Chapter 12 From SNPs to Functional Studies in Cardiovascular
Pharmacogenomics 379
Sharon Cresci
Chapter 13 Pharmacogenomics in Gastrointestinal Disorders 395
Michael Camilleri and Yuri A. Saito
Chapter 14 Pharmacogenomics in Rheumatoid Arthritis 413
Prabha Ranganathan
Chapter 15 Cancer Pharmacogenetics 437
Sharon Marsh
Chapter 16 Pharmacogenomics in the Preclinical Development
of Vaccines: Evaluation of Efficacy and Systemic
Toxicity in the Mouse Using Array Technology 447
Karin J. Regnstrom
Chapter 17 Pharmacogenomics in the Evaluation of Efficacy
and Adverse Events During Clinical Development
of Vaccines 469
Lennart J. Nilsson and Karin J. Regnstrom
Index 481
|
| adam_txt |
Contents
Chapter 1 The Integration of Personalized and Systems Medicine:
Bioinformatics Support for Pharmacogenomics
and Drug Discovery 1
Qing Yan
Chapter 2 Applications of Microarrays and Biochips
in Pharmacogenomics 21
Gary Hardiman
Chapter 3 Confounding in Genetic Association Studies
and Its Solutions 31
Donglei Hu and Elad Ziv
Chapter 4 Pharmacogenetics of Membrane Transporters: A Review
of Current Approaches 41
Tristan M. Sissung, Erin R. Gardner, Rui Gao,
and William D. Figg
Chapter 5 Pharmacogenomics of Drug-Metabolizing
Enzymes and Drug Transporters in Chemotherapy 63
Tessa M. Bosch
Chapter 6 Pharmacogenomics of G Protein-Coupled Receptor
Signaling: Insights from Health and Disease 77
Miles D. Thompson, David E. C. Cole, and Pedro A. Jose
Chapter 7 G Protein-Coupled Receptors Disrupted in Human
Genetic Disease 109
Miles D. Thompson, Maire E. Percy, W. Mclntyre Burnham,
and David E. C. Cole
ix
x Contents
Chapter 8 G Protein-Coupled Receptor Pharmacogenetics 139
Miles D. Thompson, Katherine A. Siminoivitch,
and David E. C. Cole
Chapter 9 Epigenetic Alterations of the Dopaminergic System
in Major Psychiatric Disorders 187
Hamid Mostafavi Abdolmaleky, Cassandra L. Smith,
Jin-Rong Zhou, and Sam Thiagalingam
Chapter 10 Pharmacogenomics in Alzheimer's Disease 213
Ramon Cacabelos
Chapter 11 Pharmacogenetics of Asthma 359
Gregory A. Hawkins and Stephen P. Peters
Chapter 12 From SNPs to Functional Studies in Cardiovascular
Pharmacogenomics 379
Sharon Cresci
Chapter 13 Pharmacogenomics in Gastrointestinal Disorders 395
Michael Camilleri and Yuri A. Saito
Chapter 14 Pharmacogenomics in Rheumatoid Arthritis 413
Prabha Ranganathan
Chapter 15 Cancer Pharmacogenetics 437
Sharon Marsh
Chapter 16 Pharmacogenomics in the Preclinical Development
of Vaccines: Evaluation of Efficacy and Systemic
Toxicity in the Mouse Using Array Technology 447
Karin J. Regnstrom
Chapter 17 Pharmacogenomics in the Evaluation of Efficacy
and Adverse Events During Clinical Development
of Vaccines 469
Lennart J. Nilsson and Karin J. Regnstrom
Index 481 |
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| dewey-ones | 615 - Pharmacology and therapeutics |
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| discipline | Chemie / Pharmazie Medizin |
| discipline_str_mv | Chemie / Pharmazie Medizin |
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| index_date | 2024-07-02T20:28:15Z |
| indexdate | 2024-07-09T21:14:09Z |
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| isbn | 1588298876 9781588298874 9781597452052 |
| language | English |
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| spelling | Yan, Qing Verfasser aut Pharmacogenomics in drug discovery and development ed. by Qing Yan Totowa, NJ [u.a.] Humana Press 2008 XIII, 487 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Methods in molecular biology 448 Conception de médicaments Médicaments - Efficacité ram Pharmacodynamie ram Pharmacogénétique ram Biotransformation genetics Drug Design Drug development Drugs Effectiveness Pharmacogenetics methods Pharmacogenomics Pharmacogenomics Laboratory manuals Pharmacokinetics Arzneimittelentwicklung (DE-588)4143176-5 gnd rswk-swf Pharmakogenetik (DE-588)4271255-5 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Arzneimittelentwicklung (DE-588)4143176-5 s Pharmakogenetik (DE-588)4271255-5 s b DE-604 Methods in molecular biology 448 (DE-604)BV035362695 448 HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=016436918&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Yan, Qing Pharmacogenomics in drug discovery and development Methods in molecular biology Conception de médicaments Médicaments - Efficacité ram Pharmacodynamie ram Pharmacogénétique ram Biotransformation genetics Drug Design Drug development Drugs Effectiveness Pharmacogenetics methods Pharmacogenomics Pharmacogenomics Laboratory manuals Pharmacokinetics Arzneimittelentwicklung (DE-588)4143176-5 gnd Pharmakogenetik (DE-588)4271255-5 gnd |
| subject_GND | (DE-588)4143176-5 (DE-588)4271255-5 (DE-588)4143413-4 |
| title | Pharmacogenomics in drug discovery and development |
| title_auth | Pharmacogenomics in drug discovery and development |
| title_exact_search | Pharmacogenomics in drug discovery and development |
| title_exact_search_txtP | Pharmacogenomics in drug discovery and development |
| title_full | Pharmacogenomics in drug discovery and development ed. by Qing Yan |
| title_fullStr | Pharmacogenomics in drug discovery and development ed. by Qing Yan |
| title_full_unstemmed | Pharmacogenomics in drug discovery and development ed. by Qing Yan |
| title_short | Pharmacogenomics in drug discovery and development |
| title_sort | pharmacogenomics in drug discovery and development |
| topic | Conception de médicaments Médicaments - Efficacité ram Pharmacodynamie ram Pharmacogénétique ram Biotransformation genetics Drug Design Drug development Drugs Effectiveness Pharmacogenetics methods Pharmacogenomics Pharmacogenomics Laboratory manuals Pharmacokinetics Arzneimittelentwicklung (DE-588)4143176-5 gnd Pharmakogenetik (DE-588)4271255-5 gnd |
| topic_facet | Conception de médicaments Médicaments - Efficacité Pharmacodynamie Pharmacogénétique Biotransformation genetics Drug Design Drug development Drugs Effectiveness Pharmacogenetics methods Pharmacogenomics Pharmacogenomics Laboratory manuals Pharmacokinetics Arzneimittelentwicklung Pharmakogenetik Aufsatzsammlung |
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