The handbook of metabonomics and metabolomics:
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
Amsterdam [u.a.]
Elsevier
2007
|
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | Includes index |
| Beschreibung: | x , 561 S. Ill., graph. Darst. |
| ISBN: | 0444528415 9780444528414 |
Internformat
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Datensatz im Suchindex
| _version_ | 1804137551344173056 |
|---|---|
| adam_text | Contents
Foreword vii
Sir Richard B. Sykes FRS
Preface ix
John C. Lindon, Jeremy K. Nicholson and Elaine Holmes
1 Metabonomics and Metabolomics Techniques and Their Applications
in Mammalian Systems 1
Jeremy K. Nicholson, Elaine Holmes and John C. Lindon
2 Cellular Metabolomics: The Quest for Pathway Structure 35
Oliver Fiehn
3 NMR Spectroscopy Techniques for Application to Metabonomics 55
Hans Senn and Goetz Schlotterbeck
4 High-Resolution Magic Angle Spinning NMR Spectroscopy 113
Jin-Hong Chen anct Samuel Singer
5 Chromatographi c and Electrophoretic Separations Combined with
Mass Spectrometry for Metabonomics 149
Ian D. Wilson
6 Chembmetrics Techniques for Metabonomics 171
Johan Trygg and Torbjorn Lundstedt
1 Non-linear Methods for the Analysis of Metabolic Profiles 201
Timothy M.D. Ebbels
8 Databases and Standardisation of Reporting Methods for Metabolic
Studies 227
Susanna A. Sansone, Michael D. Waters and Mark R. Viant
V
vi Contents
9 Metabonomics in Preclinical Pharmaceutical Discovery and
Development 241
Donald G. Robertson, Michael D. Reily and Glenn H. Cantor
10 Applications of Metabonomics in Clinical Pharmaceutical R D 279
Jeremy R. Everett
11 Exploiting the Potential of Metabonomics in Large Population
Studies: Three Venues 289
Burton H. Singer, Jiirg Utzinger, Carol D. Ryjf,
Yulan Wang and Elaine Holmes
12 Metabolite Profiling and Cardiovascular Disease 327
David J. Grainger
13 The Role of NMR-based Metabolomics in Cancer 345
Eeo L. Cheng and Ute Pohl
14 NMR Spectroscopy of Body Fluids as a Metabolomics Approach to
Inborn Errors of Metabolism 375
Udo F. H. Engelke, Marlies Oostendorp and Ron A. Wevers
15 A Survey of Metabonomics Approaches for
Disease Characterisation 413
John C. Lindon and Elaine Holmes
16 Metabolic Profiling: Applications in Plant Science 443
Richard N. Trethewey and Arno J. Krotzky
17 In vivo NMR Applications of Metabonomics 489
Dieter Leibfritz, Wolfgang Dreher and Wieland Willker
18 Applications of Metabonomics Within Environmental Toxicology 517
Julian L. Griffin and Richard F. Shore
19 Global Systems Biology Through Integration of Omics Results 533
John C. Lindon, Elaine Holmes and Jeremy K. Nicholson
Index 557
|
| adam_txt |
Contents
Foreword vii
Sir Richard B. Sykes FRS
Preface ix
John C. Lindon, Jeremy K. Nicholson and Elaine Holmes
1 Metabonomics and Metabolomics Techniques and Their Applications
in Mammalian Systems 1
Jeremy K. Nicholson, Elaine Holmes and John C. Lindon
2 Cellular Metabolomics: The Quest for Pathway Structure 35
Oliver Fiehn
3 NMR Spectroscopy Techniques for Application to Metabonomics 55
Hans Senn and Goetz Schlotterbeck
4 High-Resolution Magic Angle Spinning NMR Spectroscopy 113
Jin-Hong Chen anct'Samuel Singer
5 Chromatographi'c and Electrophoretic Separations Combined with
Mass Spectrometry for Metabonomics 149
Ian D. Wilson'
6 Chembmetrics Techniques for Metabonomics 171
Johan Trygg and Torbjorn Lundstedt
1 Non-linear Methods for the Analysis of Metabolic Profiles 201
Timothy M.D. Ebbels
8 Databases and Standardisation of Reporting Methods for Metabolic
Studies 227
Susanna A. Sansone, Michael D. Waters and Mark R. Viant
V
vi Contents
9 Metabonomics in Preclinical Pharmaceutical Discovery and
Development 241
Donald G. Robertson, Michael D. Reily and Glenn H. Cantor
10 Applications of Metabonomics in Clinical Pharmaceutical R D 279
Jeremy R. Everett
11 Exploiting the Potential of Metabonomics in Large Population
Studies: Three Venues 289
Burton H. Singer, Jiirg Utzinger, Carol D. Ryjf,
Yulan Wang and Elaine Holmes
12 Metabolite Profiling and Cardiovascular Disease 327
David J. Grainger
13 The Role of NMR-based Metabolomics in Cancer 345
Eeo L. Cheng and Ute Pohl
14 NMR Spectroscopy of Body Fluids as a Metabolomics Approach to
Inborn Errors of Metabolism 375
Udo F. H. Engelke, Marlies Oostendorp and Ron A. Wevers
15 A Survey of Metabonomics Approaches for
Disease Characterisation 413
John C. Lindon and Elaine Holmes
16 Metabolic Profiling: Applications in Plant Science 443
Richard N. Trethewey and Arno J. Krotzky
17 In vivo NMR Applications of Metabonomics 489
Dieter Leibfritz, Wolfgang Dreher and Wieland Willker
18 Applications of Metabonomics Within Environmental Toxicology 517
Julian L. Griffin and Richard F. Shore
19 Global Systems Biology Through Integration of "Omics" Results 533
John C. Lindon, Elaine Holmes and Jeremy K. Nicholson
Index 557 |
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| language | English |
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| spelling | The handbook of metabonomics and metabolomics ed. by John C. Lindon ... Amsterdam [u.a.] Elsevier 2007 x , 561 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Includes index Metabolism Molecular genetics Biomolecules Metabolit (DE-588)4138579-2 gnd rswk-swf Nachweis (DE-588)4115334-0 gnd rswk-swf Chemische Analyse (DE-588)4009840-0 gnd rswk-swf Metabolom (DE-588)4807318-0 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Metabolom (DE-588)4807318-0 s Chemische Analyse (DE-588)4009840-0 s DE-604 Metabolit (DE-588)4138579-2 s Nachweis (DE-588)4115334-0 s Lindon, John C. Sonstige oth HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=016434582&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | The handbook of metabonomics and metabolomics Metabolism Molecular genetics Biomolecules Metabolit (DE-588)4138579-2 gnd Nachweis (DE-588)4115334-0 gnd Chemische Analyse (DE-588)4009840-0 gnd Metabolom (DE-588)4807318-0 gnd |
| subject_GND | (DE-588)4138579-2 (DE-588)4115334-0 (DE-588)4009840-0 (DE-588)4807318-0 (DE-588)4143413-4 |
| title | The handbook of metabonomics and metabolomics |
| title_auth | The handbook of metabonomics and metabolomics |
| title_exact_search | The handbook of metabonomics and metabolomics |
| title_exact_search_txtP | The handbook of metabonomics and metabolomics |
| title_full | The handbook of metabonomics and metabolomics ed. by John C. Lindon ... |
| title_fullStr | The handbook of metabonomics and metabolomics ed. by John C. Lindon ... |
| title_full_unstemmed | The handbook of metabonomics and metabolomics ed. by John C. Lindon ... |
| title_short | The handbook of metabonomics and metabolomics |
| title_sort | the handbook of metabonomics and metabolomics |
| topic | Metabolism Molecular genetics Biomolecules Metabolit (DE-588)4138579-2 gnd Nachweis (DE-588)4115334-0 gnd Chemische Analyse (DE-588)4009840-0 gnd Metabolom (DE-588)4807318-0 gnd |
| topic_facet | Metabolism Molecular genetics Biomolecules Metabolit Nachweis Chemische Analyse Metabolom Aufsatzsammlung |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=016434582&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
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