Behavioral genetics:
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
New York
Worth
2008
|
| Ausgabe: | 5. ed. |
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | XVIII, 532 S. Ill., graph. Darst. |
| ISBN: | 9781429205771 1429205776 |
Internformat
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Datensatz im Suchindex
| _version_ | 1804137544219099136 |
|---|---|
| adam_text | Titel: Behavioral genetics
Autor: Plomin, Robert
Jahr: 2008
CONTENTS
About the Authors xv
Preface xvii
Overview
chapter
Mendel s Laws of Heredity 5
Mendel s First Law of Heredity 6
Huntington Disease 7
Box 2.1 Gregor Mendel s Luck 8
Phenylketonuria 10
Box 2.2 How Do We Know That 1 in 50 People Are
Carriers for PKU? 12
Mendel s Second Law of Heredity 13
Summary 17
CHAPTER
Beyond Mendel s Laws 19
Genes on the X Chromosome 20
Other Exceptions to Mendel s Laws 22
New Mutations 22
Changes in Chromosomes 22
Expanded Triplet Repeats 24
Genomic Imprinting 26
Complex Traits 27
Schizophrenia 27
General Cognitive Ability 29
Pea Size 30
vi CONTENTS
Multiple-Gene Inheritance 32
Quantitative Genetics 34
Box 3.1 Liability-Threshold Model of Disorders 36
Summary 38
chapter!
DNA: The Basis of Heredity 40
DNA 40
Box 4.1 The Central Dogma of Molecular Genetics 44
Gene Expression 47
Mutations 49
Detecting Polymorphisms 51
Box 4.2 DNA Markers 52
Chromosomes 54
Summary 58
CHAPTER
Nature, Nurture, and Behavior 59
Genetic Experiments to Investigate Animal Behavior 60
Selection Studies 63
Inbred Strain Studies 66
Investigating the Genetics of Human Behavior 70
Adoption Designs 70
Close-Up Lindon Eaves 71
Box 5.1 The First Adoption Study of Schizophrenia 74
Twin Design 75
Box 5.2 Issues in Adoption Studies 76
Box 5.3 The Twin Method 78
Combination 80
Close-Up Nancy Pedersen 81
Heritability 82
Interpreting Heritability 85
Contents vii
Close-Up Nick Martin 89
Beyond Heritability 89
Equality 91
Summary 91
CHAPTER
Identifying Genes 92
Animal Behavior 93
Creating Mutations 94
Quantitative Trait Loci 99
Close-Up Jonathan Flint 102
Synteny Homology 105
Human Behavior 105
Linkage: Single-Gene Disorders 107
Linkage: Complex Disorders 108
Association: Candidate Genes 108
Box 6.1 Affected Sib-Paii Linkage Design 109
Association: Genomewide 111
Box 6.2 SNP Micioairays 112
Box 6.3 Genetic Counseling 114
Ethics and the Future 115
Box 6.4 GATTACA? 116
Summary 117
CHAPTERÝ
Cognitive Disabilities 119
General Cognitive Disability: Quantitative Genetics 120
General Cognitive Disability: Single-Gene Disorders 122
Phenylketonuria 122
Fragile X Syndrome 123
Rett Syndrome 125
Duchenne Muscular Dystrophy 126
viii CONTENTS
Lesch-Nyhan Syndrome 126
Neurofibromatosis Type 1 127
General Cognitive Disability: Chromosomal
Abnormalities 129
Down Syndrome 130
Sex Chromosome Abnormalities 132
Learning Disorders 133
Reading Disability 134
Close-Up Stephen A. Petrill 135
Box 7.1 DF Extremes Analysis 136
Close-Up Shelley Smith 140
Communication Disorders 141
Mathematics Disability 142
Comorbidity between Learning Disabilities 142
Dementia 142
Summary 145
CHAPTER 1
General Cognitive Ability 147
Historical Highlights 149
Animal Research 149
Box 8.1 Francis Galton 150
Human Research 155
Overview of Genetic Research 156
Genetic Influence 156
Close-Up Thomas J. Bouchard, Jr. 158
Environmental Influence 159
Assortative Mating 160
Nonadditive Genetic Variance 161
Developmental Research 163
Does Heritability Change During Development? 163
Do Genetic Factors Contribute to Developmental Change? 168
Contents ix
Identifying Genes 169
Summary 172
chapter!
Specific Cognitive Abilities 173
Broad Factors of Specific Cognitive Abilities 173
Information-Processing Measures 181
Multivariate Genetic Analysis: Levels of Processing 183
Close-Up JukoAndo 186
School Achievement 187
Identifying Genes 192
Summary 193
chapter!
Schizophrenia 194
Family Studies 195
Box 10.1 The Beginnings of Psychiatric Genetics:
Bethlem Royal and Maudsley Hospitals 196
Twin Studies 198
Close-Up Irving Gottesman 199
Adoption Studies 201
Schizophrenia or Schizophrenias? 203
Close-Up Kenneth Kendlei 204
Identifying Genes 205
Summary 207
chapter!
Other Adult Psychopathology 208
Mood Disorders 208
Family Studies 209
Twin Studies 210
Close-Up Dorret Boomsma 211
x CONTENTS
Adoption Studies 213
Identifying Genes 213
Anxiety Disorders 215
Close-Up SooHyunBhee 216
Other Disorders 218
Co-Occurrence of Disorders 220
Identifying Genes 223
Summary 223
chapter!
Developmental Psychopathology 225
Autism 226
Family and Twin Studies 226
Identifying Genes 228
Attention-Deficit and Disruptive Behavior Disorders 229
Close-Up Anita Thapai 229
Twin Studies 230
Identifying Genes 232
Anxiety Disorders 233
Other Disorders 234
Summary 236
CHAPTER ¦¦=IIM«aa*l
Personality and Personality Disorders 238
Self-Report Questionnaires 239
Other Measures of Personality 242
Other Findings 245
Situations 245
Development 246
Nature-Nurture Interplay 246
Close-Up Hill Goldsmith 247
Contents xi
Personality and Social Psychology 248
Relationships 248
Self-Esteem 250
Attitudes and Interests 250
Close-Up MattMcGue 252
Personality Disorders 253
Schizotypal and Obsessive-Compulsive
Personality Disorders 254
Antisocial Personality Disorder and Criminal Behavior 255
Identifying Genes 259
Summary 262
CHAPTER
Health Psychology and Aging 264
Health Psychology 264
Close-Up John K. Hewitt 265
Body Weight and Obesity 265
Addictions 270
Close-Up John Crabbe 277
Psychology and Aging 280
Summary 283
CHAPTERiaiaaaaM
Pathways between Genes and Behavior 285
Box 15.1 Levels of Analysis 286
The Transcriptome: Gene Expression throughout
the Genome 287
Gene Expression Profiles: RNA Microarrays 288
Close-Up Seth Giant 289
Genetical Genomics 290
Gene Expression as a Biological Basis
for Environmental Influence 290
xii CONTENTS
The Proteome: Proteins Coded throughout
the Transcriptome 292
The Brain 294
Circadian Rhythms 295
Box 15.2 Endophenotypes 296
Learning and Memory 299
Emotion 302
Close-Up Ahmad Haiti 303
Summary 304
CHAPTERÝ
The Interplay between Genes and Environment 305
Nonshared Environment 307
Estimating Nonshared Environment 308
Identifying Specific Nonshared Environment 309
Identifying Specific Nonshared Environment That
Predicts Behavioral Outcomes 311
Implications 314
Genotype-Environment Correlation 315
The Nature of Nurture 315
Three Types of Genotype-Environment Correlation 318
Three Methods to Detect Genotype-Environment
Correlation 320
Implications 324
Genotype-Environment Interaction 325
Animal Models 326
Adoption Studies 327
Twin Studies 328
Close-Up Terrie E. Moffitt and Avshalom Caspi 329
DNA 329
Summary 332
CHAPTE
rl SEVENTEEN
Evolution and Behavior 334
Charles Darwin 334
Contents xiii
Inclusive Fitness 338
Sociobiology 338
Population Genetics 340
Evolutionary Psychology 342
Close-Up David M. Buss 343
Instincts 344
Empirical Evidence 345
Box 17.1 Mate Preference and the Major
Histocompatibility Complex 346
Box 17.2 Selection for Beauty 348
Close-Up Margo Wilson and Martin Daly 350
Summary 351
CHAPTER
The Future of Behavioral Genetics 352
Quantitative Genetics 352
Molecular Genetics 355
Nature and Nurture 356
APPENDIX_____________________________________
Statistical Methods in Behavioral Genetics 359
1 Introduction 359
BoxA.1 Behavioral Genetic Interactive Modules 360
Close-Up Shaun Purcell 361
1.1 Variation and covariation: statistical descriptions
of individual differences 361
2 Quantitative Genetics 374
2.1 The biométrie model 374
2.2 Estimating variance components 379
Close-Up Michael C. Neale 384
3 Molecular Genetics 402
3.1 Linkage analysis 402
3.2 Association analysis 405
xiv CONTENTS
Glossary 411
References 423
Web Sites 503
Name Index 507
Subject Index 527
|
| adam_txt |
Titel: Behavioral genetics
Autor: Plomin, Robert
Jahr: 2008
CONTENTS
About the Authors xv
Preface xvii
Overview
chapter
Mendel's Laws of Heredity 5
Mendel's First Law of Heredity 6
Huntington Disease 7
Box 2.1 Gregor Mendel's Luck 8
Phenylketonuria 10
Box 2.2 How Do We Know That 1 in 50 People Are
Carriers for PKU? 12
Mendel's Second Law of Heredity 13
Summary 17
CHAPTER
Beyond Mendel's Laws 19
Genes on the X Chromosome 20
Other Exceptions to Mendel's Laws 22
New Mutations 22
Changes in Chromosomes 22
Expanded Triplet Repeats 24
Genomic Imprinting 26
Complex Traits 27
Schizophrenia 27
General Cognitive Ability 29
Pea Size 30
vi CONTENTS
Multiple-Gene Inheritance 32
Quantitative Genetics 34
Box 3.1 Liability-Threshold Model of Disorders 36
Summary 38
chapter!
DNA: The Basis of Heredity 40
DNA 40
Box 4.1 The "Central Dogma " of Molecular Genetics 44
Gene Expression 47
Mutations 49
Detecting Polymorphisms 51
Box 4.2 DNA Markers 52
Chromosomes 54
Summary 58
CHAPTER
Nature, Nurture, and Behavior 59
Genetic Experiments to Investigate Animal Behavior 60
Selection Studies 63
Inbred Strain Studies 66
Investigating the Genetics of Human Behavior 70
Adoption Designs 70
Close-Up Lindon Eaves 71
Box 5.1 The First Adoption Study of Schizophrenia 74
Twin Design 75
Box 5.2 Issues in Adoption Studies 76
Box 5.3 The Twin Method 78
Combination 80
Close-Up Nancy Pedersen 81
Heritability 82
Interpreting Heritability 85
Contents vii
Close-Up Nick Martin 89
Beyond Heritability 89
Equality 91
Summary 91
CHAPTER
Identifying Genes 92
Animal Behavior 93
Creating Mutations 94
Quantitative Trait Loci 99
Close-Up Jonathan Flint 102
Synteny Homology 105
Human Behavior 105
Linkage: Single-Gene Disorders 107
Linkage: Complex Disorders 108
Association: Candidate Genes 108
Box 6.1 Affected Sib-Paii Linkage Design 109
Association: Genomewide 111
Box 6.2 SNP Micioairays 112
Box 6.3 Genetic Counseling 114
Ethics and the Future 115
Box 6.4 GATTACA? 116
Summary 117
CHAPTERÝ
Cognitive Disabilities 119
General Cognitive Disability: Quantitative Genetics 120
General Cognitive Disability: Single-Gene Disorders 122
Phenylketonuria 122
Fragile X Syndrome 123
Rett Syndrome 125
Duchenne Muscular Dystrophy 126
viii CONTENTS
Lesch-Nyhan Syndrome 126
Neurofibromatosis Type 1 127
General Cognitive Disability: Chromosomal
Abnormalities 129
Down Syndrome 130
Sex Chromosome Abnormalities 132
Learning Disorders 133
Reading Disability 134
Close-Up Stephen A. Petrill 135
Box 7.1 DF Extremes Analysis 136
Close-Up Shelley Smith 140
Communication Disorders 141
Mathematics Disability 142
Comorbidity between Learning Disabilities 142
Dementia 142
Summary 145
CHAPTER 1
General Cognitive Ability 147
Historical Highlights 149
Animal Research 149
Box 8.1 Francis Galton 150
Human Research 155
Overview of Genetic Research 156
Genetic Influence 156
Close-Up Thomas J. Bouchard, Jr. 158
Environmental Influence 159
Assortative Mating 160
Nonadditive Genetic Variance 161
Developmental Research 163
Does Heritability Change During Development? 163
Do Genetic Factors Contribute to Developmental Change? 168
Contents ix
Identifying Genes 169
Summary 172
chapter!
Specific Cognitive Abilities 173
Broad Factors of Specific Cognitive Abilities 173
Information-Processing Measures 181
Multivariate Genetic Analysis: Levels of Processing 183
Close-Up JukoAndo 186
School Achievement 187
Identifying Genes 192
Summary 193
chapter!
Schizophrenia 194
Family Studies 195
Box 10.1 The Beginnings of Psychiatric Genetics:
Bethlem Royal and Maudsley Hospitals 196
Twin Studies 198
Close-Up Irving Gottesman 199
Adoption Studies 201
Schizophrenia or Schizophrenias? 203
Close-Up Kenneth Kendlei 204
Identifying Genes 205
Summary 207
chapter!
Other Adult Psychopathology 208
Mood Disorders 208
Family Studies 209
Twin Studies 210
Close-Up Dorret Boomsma 211
x CONTENTS
Adoption Studies 213
Identifying Genes 213
Anxiety Disorders 215
Close-Up SooHyunBhee 216
Other Disorders 218
Co-Occurrence of Disorders 220
Identifying Genes 223
Summary 223
chapter!
Developmental Psychopathology 225
Autism 226
Family and Twin Studies 226
Identifying Genes 228
Attention-Deficit and Disruptive Behavior Disorders 229
Close-Up Anita Thapai 229
Twin Studies 230
Identifying Genes 232
Anxiety Disorders 233
Other Disorders 234
Summary 236
CHAPTER ¦¦=IIM«aa*l
Personality and Personality Disorders 238
Self-Report Questionnaires 239
Other Measures of Personality 242
Other Findings 245
Situations 245
Development 246
Nature-Nurture Interplay 246
Close-Up Hill Goldsmith 247
Contents xi
Personality and Social Psychology 248
Relationships 248
Self-Esteem 250
Attitudes and Interests 250
Close-Up MattMcGue 252
Personality Disorders 253
Schizotypal and Obsessive-Compulsive
Personality Disorders 254
Antisocial Personality Disorder and Criminal Behavior 255
Identifying Genes 259
Summary 262
CHAPTER
Health Psychology and Aging 264
Health Psychology 264
Close-Up John K. Hewitt 265
Body Weight and Obesity 265
Addictions 270
Close-Up John Crabbe 277
Psychology and Aging 280
Summary 283
CHAPTERiaiaaaaM
Pathways between Genes and Behavior 285
Box 15.1 Levels of Analysis 286
The Transcriptome: Gene Expression throughout
the Genome 287
Gene Expression Profiles: RNA Microarrays 288
Close-Up Seth Giant 289
Genetical Genomics 290
Gene Expression as a Biological Basis
for Environmental Influence 290
xii CONTENTS
The Proteome: Proteins Coded throughout
the Transcriptome 292
The Brain 294
Circadian Rhythms 295
Box 15.2 Endophenotypes 296
Learning and Memory 299
Emotion 302
Close-Up Ahmad Haiti 303
Summary 304
CHAPTERÝ
The Interplay between Genes and Environment 305
Nonshared Environment 307
Estimating Nonshared Environment 308
Identifying Specific Nonshared Environment 309
Identifying Specific Nonshared Environment That
Predicts Behavioral Outcomes 311
Implications 314
Genotype-Environment Correlation 315
The Nature of Nurture 315
Three Types of Genotype-Environment Correlation 318
Three Methods to Detect Genotype-Environment
Correlation 320
Implications 324
Genotype-Environment Interaction 325
Animal Models 326
Adoption Studies 327
Twin Studies 328
Close-Up Terrie E. Moffitt and Avshalom Caspi 329
DNA 329
Summary 332
CHAPTE
rl SEVENTEEN
Evolution and Behavior 334
Charles Darwin 334
Contents xiii
Inclusive Fitness 338
Sociobiology 338
Population Genetics 340
Evolutionary Psychology 342
Close-Up David M. Buss 343
Instincts 344
Empirical Evidence 345
Box 17.1 Mate Preference and the Major
Histocompatibility Complex 346
Box 17.2 Selection for Beauty 348
Close-Up Margo Wilson and Martin Daly 350
Summary 351
CHAPTER
The Future of Behavioral Genetics 352
Quantitative Genetics 352
Molecular Genetics 355
Nature and Nurture 356
APPENDIX_
Statistical Methods in Behavioral Genetics 359
1 Introduction 359
BoxA.1 Behavioral Genetic Interactive Modules 360
Close-Up Shaun Purcell 361
1.1 Variation and covariation: statistical descriptions
of individual differences 361
2 Quantitative Genetics 374
2.1 The biométrie model 374
2.2 Estimating variance components 379
Close-Up Michael C. Neale 384
3 Molecular Genetics 402
3.1 Linkage analysis 402
3.2 Association analysis 405
xiv CONTENTS
Glossary 411
References 423
Web Sites 503
Name Index 507
Subject Index 527 |
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| index_date | 2024-07-02T20:25:12Z |
| indexdate | 2024-07-09T21:13:59Z |
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| spelling | Behavioral genetics Robert Plomin ... 5. ed. New York Worth 2008 XVIII, 532 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Behavior genetics Verhaltensgenetik (DE-588)4187763-9 gnd rswk-swf Erbpsychologie (DE-588)4131722-1 gnd rswk-swf (DE-588)4123623-3 Lehrbuch gnd-content Verhaltensgenetik (DE-588)4187763-9 s Erbpsychologie (DE-588)4131722-1 s DE-604 Plomin, Robert 1948- Sonstige (DE-588)104831149X oth HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=016430083&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Behavioral genetics Behavior genetics Verhaltensgenetik (DE-588)4187763-9 gnd Erbpsychologie (DE-588)4131722-1 gnd |
| subject_GND | (DE-588)4187763-9 (DE-588)4131722-1 (DE-588)4123623-3 |
| title | Behavioral genetics |
| title_auth | Behavioral genetics |
| title_exact_search | Behavioral genetics |
| title_exact_search_txtP | Behavioral genetics |
| title_full | Behavioral genetics Robert Plomin ... |
| title_fullStr | Behavioral genetics Robert Plomin ... |
| title_full_unstemmed | Behavioral genetics Robert Plomin ... |
| title_short | Behavioral genetics |
| title_sort | behavioral genetics |
| topic | Behavior genetics Verhaltensgenetik (DE-588)4187763-9 gnd Erbpsychologie (DE-588)4131722-1 gnd |
| topic_facet | Behavior genetics Verhaltensgenetik Erbpsychologie Lehrbuch |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=016430083&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| work_keys_str_mv | AT plominrobert behavioralgenetics |