Management of the oncologic patient:
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
Philadelphia [u.a.]
Saunders
2008
|
| Schriftenreihe: | The dental clinics of North America
52,1 |
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | XIV, 258 S. Ill. |
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| 650 | 4 | |a Cancer |x Complications | |
| 650 | 4 | |a Cancer |x Treatment | |
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| 650 | 4 | |a Head |x Cancer | |
| 650 | 4 | |a Mouth Neoplasms | |
| 650 | 4 | |a Mouth |x Cancer | |
| 650 | 4 | |a Neck |x Cancer | |
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| adam_text | CONTENTS
Preface xiii
Sook-Bin Woo and Nathaniel S. Treister
Multidisciplinary Approach to Cancer Treatment:
Focus on Head and Neck Cancer 1
Robert Haddad, Donald Annino, and Roy B. Tishler
This article focuses on squamous cell carcinoma of the head and neck
(SCCHN), the most common malignancy of the head and neck area.
Early detection limits morbidity of treatment and increases the
chances of a cure. The treatment of SCCHN is often multidisciplinary
in nature and provides a model for how multimodality therapy may
be applied for optimal patient management. The role of surgery in
SCCHN is continually undergoing evolution, and the surgeon s role
in the multidisciplinary treatment of head and neck cancers has
changed as more cancers are being treated by chemoradiotherapy.
Salvage surgery has become more common, and with it the increased
challenges in managing metastatic disease to neck nodes as well as
managing failure of organ preservation treatments. Surgeons
continue to develop and refine reconstruction techniques to optimize
cosmetic and functional outcomes.
Dental Treatment Planning and Management in the Patient
Who Has Cancer 19
Michael T. Brennan, Sook-Bin Woo, and Peter B. Lockhart
The oral cavity has the potential to be a major source of short-term
and long-term complications from cancer therapy. Appropriate
evaluation and elimination of potential sources of oral infection
before cancer therapy is vital because oral bacteria are a known
source of bacteremia and septicemia during cancer therapy. Cancer
diagnosis with previous and planned treatment, past medical
history, past dental history, current medications, drug allergies,
social history, family history, laboratory values, extraoral findings,
intraoral findings, and radiographic findings must all be evaluated
in planning dental treatment for these complex cases.
VOLUME 52 • NUMBER 1 • JANUARY 2008 vii
Managament of Patients Who Have Undergone Head
and Neck Cancer Therapy 39
Dena J. Fischer and Joel B. Epstein
Patients who undergo treatment for head and neck cancers often
suffer from acute or late reactions to therapy. Severity of these oral
complications may be based on the location and extent of tumor, as
well as the type and extent of treatment. Some complications are
transient, whereas others require a lifetime of management
secondary to damage that results in permanent dysfunction.
Patients who have a history of head and neck cancers are also at
an increased risk for recurrences or second malignancies, and
therefore require close follow-up. Dental professionals should
provide preventive and supportive care, including education and
symptom management, for patients experiencing oral complica¬
tions related to cancer therapy, and should closely monitor
patients level of distress, ability to cope, and treatment response.
Management of Oral Mucositis in Patients Who Have Cancer 61
Rajesh V. Lalla, Stephen T. Sonis, and Douglas E. Peterson
Oral mucositis is a clinically important and sometimes dose-
limiting complication of cancer therapy. Mucositis lesions can be
painful, affect nutrition and quality of life, and have a significant
economic impact. The pathogenesis of oral mucositis is multi-
factorial and complex. This review discusses the morbidity,
economic impact, pathogenesis and clinical course of mucositis.
Current clinical management of oral mucositis is largely focused on
palliative measures such as pain management, nutritional support
and maintenance of good oral hygiene. However, several promis¬
ing therapeutic agents are in various stages of clinical development
for the management of oral mucositis. These agents are discussed
in the context of recently updated evidence-based clinical manage¬
ment guidelines.
Oral Graft-Versus-Host Disease 79
Mark M. Schubert and Maria Elvira Pizzigatti Correa
Hematopoietic cell transplantation is used to treat malignancies,
hematologic and immune deficiency states, marrow failure
syndromes, and autoimmune diseases. Graft-versus-host disease
(GVHD) is a clinical syndrome seen following allogeneic trans¬
plantation where donorderived immunocompetent T cells and
inflammatory responses attack host tissues. GVHD can cause
significant morbidity and even result in mortality. The oral cavity is
a frequently involved site with clinical changes resembling auto¬
immune collagen vascular diseases. Recognition, diagnosis, and
monitoring of oral GVHD can help with diagnosis and grading of
GVHD and judging responses to therapy. Topical and local
management of symptomatic oral GVHD can reduce oral
symptoms that can interfere with oral function and quality of
viii CONTENTS
life, and can reduce the need for more intensive immunosuppres-
sive systemic therapies.
Biophosphonate-Related Osteonecrosis of the Jaws 111
Salvatore L. Ruggiero and Sook-Bin Woo
In 2003 and 2004, the first reports of patients who developed
necrosis of the jawbones while taking biophosphonates appeared in
literature; most patients were on this drug for treatment of cancer
and some osteoporosis. Since then, more than 500 cases have been
identified and the number of these cases continues to grow. This
article reviews the action of bisphosphonates, the condition called
bisphosphonate-associated osteonecrosis of the jaws, strategies to
minimize occurrence, and treatment of this condition.
Management of Oral Infections in Cancer Patients 129
Mark A. Lerman, Joel Laudenbach, Francisco M. Marty,
Lindsey R. Baden, and Nathaniel S. Treister
The myelosuppressive and mucosal-damaging consequences of
cancer and cancer therapies place patients at high risk for
developing infectious complications. Bacterial, fungal, and viral
infections are all commonly encountered in the oral cavity,
contributing to both morbidity and mortality in this patient
population. Prevention, early and definitive diagnosis, and
appropriate management are critical to ensure optimal treatment
outcomes. With the majority of cancer patients treated as out¬
patients in the community setting, oral health care professionals
play an important role in managing such infectious complications
of cancer therapy.
Considerations in the Pediatric Population with Cancer 155
Catherine H. Hong and Marcio daFonseca
This article is divided into three time periods according to the
different phases of cancer treatment: pre, inter, and postcancer
therapy. The purpose of dental protocols prior to cancer therapy
and the incidence and management of acute and long term oral
complications from cancer therapy in the pediatric population are
discussed.
Orofacial Pain and Neurosurgery Disorders and Dysfunction
in Cancer Patients 183
Glenn T. Clark and Saravanan Ram
Orofacial pain and altered nerve sensation may be the initial sign of
oropharyngeal or nasopharyngeal cancer. This article focuses on
the most common orofacial pain conditions and neurosensory
alterations that affect cancer patients, such as neuropathic pain,
muscle spasm or contractures, mucositis, and increased or
CONTENTS ix
decreased sensory discrimination in the affected area. The various
pharmacotherapeutic modalities for cancer pain management
ranging from non steroidal anti-inflammatory drugs (NSAIDs)
for mild pain to opioids for severe pain are discussed in detail.
Oral Manifestations of Internal Malignancy
and Paraneoplastic Syndromes 203
Victoria L. Woo and Rafik Abdelsayed
Malignant rumors of visceral organs are a fundamental feature of
familial cancer and paraneoplastic syndromes. In many instances,
the presence of an internal and often occult malignancy may be
forewarned by various external manifestations. Several of these
findings are preferentially localized to the head and neck region,
including the oral cavity proper. This places the dental practitioner
in a unique position to detect these markers of occult neoplastic
involvement. Because these markers may present before an
established syndrome or cancer diagnosis, even representing the
first expression of disease in some cases, early recognition by a
dentist may lead to timely diagnosis and management of these
cancer-associated syndromes.
Psychosocial and Economic Impact of Cancer 231
Linda S. Elting, Elenir B.C. Avritscher, Catherine D. Cooksley,
Marylou Cardenas-Turanzas, Adam S. Garden,
and Mark S. Chambers
This article explores the psychosocial and economic implications of
cancer and their relevance to the clinician. After a general overview
of the topic, the authors focus on aspects of particular importance
to the dental professional, including the psychosocial and
economic implications of the oral complications of cancer and its
therapy, head and neck cancers, and special issues among children
with cancer and cancer survivors.
Index 253
x CONTENTS
|
| adam_txt |
CONTENTS
Preface xiii
Sook-Bin Woo and Nathaniel S. Treister
Multidisciplinary Approach to Cancer Treatment:
Focus on Head and Neck Cancer 1
Robert Haddad, Donald Annino, and Roy B. Tishler
This article focuses on squamous cell carcinoma of the head and neck
(SCCHN), the most common malignancy of the head and neck area.
Early detection limits morbidity of treatment and increases the
chances of a cure. The treatment of SCCHN is often multidisciplinary
in nature and provides a model for how multimodality therapy may
be applied for optimal patient management. The role of surgery in
SCCHN is continually undergoing evolution, and the surgeon's role
in the multidisciplinary treatment of head and neck cancers has
changed as more cancers are being treated by chemoradiotherapy.
Salvage surgery has become more common, and with it the increased
challenges in managing metastatic disease to neck nodes as well as
managing failure of organ preservation treatments. Surgeons
continue to develop and refine reconstruction techniques to optimize
cosmetic and functional outcomes.
Dental Treatment Planning and Management in the Patient
Who Has Cancer 19
Michael T. Brennan, Sook-Bin Woo, and Peter B. Lockhart
The oral cavity has the potential to be a major source of short-term
and long-term complications from cancer therapy. Appropriate
evaluation and elimination of potential sources of oral infection
before cancer therapy is vital because oral bacteria are a known
source of bacteremia and septicemia during cancer therapy. Cancer
diagnosis with previous and planned treatment, past medical
history, past dental history, current medications, drug allergies,
social history, family history, laboratory values, extraoral findings,
intraoral findings, and radiographic findings must all be evaluated
in planning dental treatment for these complex cases.
VOLUME 52 • NUMBER 1 • JANUARY 2008 vii
Managament of Patients Who Have Undergone Head
and Neck Cancer Therapy 39
Dena J. Fischer and Joel B. Epstein
Patients who undergo treatment for head and neck cancers often
suffer from acute or late reactions to therapy. Severity of these oral
complications may be based on the location and extent of tumor, as
well as the type and extent of treatment. Some complications are
transient, whereas others require a lifetime of management
secondary to damage that results in permanent dysfunction.
Patients who have a history of head and neck cancers are also at
an increased risk for recurrences or second malignancies, and
therefore require close follow-up. Dental professionals should
provide preventive and supportive care, including education and
symptom management, for patients experiencing oral complica¬
tions related to cancer therapy, and should closely monitor
patients' level of distress, ability to cope, and treatment response.
Management of Oral Mucositis in Patients Who Have Cancer 61
Rajesh V. Lalla, Stephen T. Sonis, and Douglas E. Peterson
Oral mucositis is a clinically important and sometimes dose-
limiting complication of cancer therapy. Mucositis lesions can be
painful, affect nutrition and quality of life, and have a significant
economic impact. The pathogenesis of oral mucositis is multi-
factorial and complex. This review discusses the morbidity,
economic impact, pathogenesis and clinical course of mucositis.
Current clinical management of oral mucositis is largely focused on
palliative measures such as pain management, nutritional support
and maintenance of good oral hygiene. However, several promis¬
ing therapeutic agents are in various stages of clinical development
for the management of oral mucositis. These agents are discussed
in the context of recently updated evidence-based clinical manage¬
ment guidelines.
Oral Graft-Versus-Host Disease 79
Mark M. Schubert and Maria Elvira Pizzigatti Correa
Hematopoietic cell transplantation is used to treat malignancies,
hematologic and immune deficiency states, marrow failure
syndromes, and autoimmune diseases. Graft-versus-host disease
(GVHD) is a clinical syndrome seen following allogeneic trans¬
plantation where donorderived immunocompetent T cells and
inflammatory responses attack host tissues. GVHD can cause
significant morbidity and even result in mortality. The oral cavity is
a frequently involved site with clinical changes resembling auto¬
immune collagen vascular diseases. Recognition, diagnosis, and
monitoring of oral GVHD can help with diagnosis and grading of
GVHD and judging responses to therapy. Topical and local
management of symptomatic oral GVHD can reduce oral
symptoms that can interfere with oral function and quality of
viii CONTENTS
life, and can reduce the need for more intensive immunosuppres-
sive systemic therapies.
Biophosphonate-Related Osteonecrosis of the Jaws 111
Salvatore L. Ruggiero and Sook-Bin Woo
In 2003 and 2004, the first reports of patients who developed
necrosis of the jawbones while taking biophosphonates appeared in
literature; most patients were on this drug for treatment of cancer
and some osteoporosis. Since then, more than 500 cases have been
identified and the number of these cases continues to grow. This
article reviews the action of bisphosphonates, the condition called
bisphosphonate-associated osteonecrosis of the jaws, strategies to
minimize occurrence, and treatment of this condition.
Management of Oral Infections in Cancer Patients 129
Mark A. Lerman, Joel Laudenbach, Francisco M. Marty,
Lindsey R. Baden, and Nathaniel S. Treister
The myelosuppressive and mucosal-damaging consequences of
cancer and cancer therapies place patients at high risk for
developing infectious complications. Bacterial, fungal, and viral
infections are all commonly encountered in the oral cavity,
contributing to both morbidity and mortality in this patient
population. Prevention, early and definitive diagnosis, and
appropriate management are critical to ensure optimal treatment
outcomes. With the majority of cancer patients treated as out¬
patients in the community setting, oral health care professionals
play an important role in managing such infectious complications
of cancer therapy.
Considerations in the Pediatric Population with Cancer 155
Catherine H. Hong and Marcio daFonseca
This article is divided into three time periods according to the
different phases of cancer treatment: pre, inter, and postcancer
therapy. The purpose of dental protocols prior to cancer therapy
and the incidence and management of acute and long term oral
complications from cancer therapy in the pediatric population are
discussed.
Orofacial Pain and Neurosurgery Disorders and Dysfunction
in Cancer Patients 183
Glenn T. Clark and Saravanan Ram
Orofacial pain and altered nerve sensation may be the initial sign of
oropharyngeal or nasopharyngeal cancer. This article focuses on
the most common orofacial pain conditions and neurosensory
alterations that affect cancer patients, such as neuropathic pain,
muscle spasm or contractures, mucositis, and increased or
CONTENTS ix
decreased sensory discrimination in the affected area. The various
pharmacotherapeutic modalities for cancer pain management
ranging from non steroidal anti-inflammatory drugs (NSAIDs)
for mild pain to opioids for severe pain are discussed in detail.
Oral Manifestations of Internal Malignancy
and Paraneoplastic Syndromes 203
Victoria L. Woo and Rafik Abdelsayed
Malignant rumors of visceral organs are a fundamental feature of
familial cancer and paraneoplastic syndromes. In many instances,
the presence of an internal and often occult malignancy may be
forewarned by various external manifestations. Several of these
findings are preferentially localized to the head and neck region,
including the oral cavity proper. This places the dental practitioner
in a unique position to detect these "markers" of occult neoplastic
involvement. Because these markers may present before an
established syndrome or cancer diagnosis, even representing the
first expression of disease in some cases, early recognition by a
dentist may lead to timely diagnosis and management of these
cancer-associated syndromes.
Psychosocial and Economic Impact of Cancer 231
Linda S. Elting, Elenir B.C. Avritscher, Catherine D. Cooksley,
Marylou Cardenas-Turanzas, Adam S. Garden,
and Mark S. Chambers
This article explores the psychosocial and economic implications of
cancer and their relevance to the clinician. After a general overview
of the topic, the authors focus on aspects of particular importance
to the dental professional, including the psychosocial and
economic implications of the oral complications of cancer and its
therapy, head and neck cancers, and special issues among children
with cancer and cancer survivors.
Index 253
x CONTENTS |
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| series | The dental clinics of North America |
| series2 | The dental clinics of North America |
| spelling | Management of the oncologic patient guest eds. Sook-Bin Woo ... Philadelphia [u.a.] Saunders 2008 XIV, 258 S. Ill. txt rdacontent n rdamedia nc rdacarrier The dental clinics of North America 52,1 Cancer Complications Cancer Treatment Dentistry Head and Neck Neoplasms Head Cancer Mouth Neoplasms Mouth Cancer Neck Cancer Neoplasms complications Neoplasms therapy Krebskranker (DE-588)4032913-6 gnd rswk-swf Zahnärztliche Behandlung (DE-588)4190487-4 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Krebskranker (DE-588)4032913-6 s Zahnärztliche Behandlung (DE-588)4190487-4 s DE-604 Woo, Sook-Bin Sonstige oth The dental clinics of North America 52,1 (DE-604)BV000003657 52,1 HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=016395858&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Management of the oncologic patient The dental clinics of North America Cancer Complications Cancer Treatment Dentistry Head and Neck Neoplasms Head Cancer Mouth Neoplasms Mouth Cancer Neck Cancer Neoplasms complications Neoplasms therapy Krebskranker (DE-588)4032913-6 gnd Zahnärztliche Behandlung (DE-588)4190487-4 gnd |
| subject_GND | (DE-588)4032913-6 (DE-588)4190487-4 (DE-588)4143413-4 |
| title | Management of the oncologic patient |
| title_auth | Management of the oncologic patient |
| title_exact_search | Management of the oncologic patient |
| title_exact_search_txtP | Management of the oncologic patient |
| title_full | Management of the oncologic patient guest eds. Sook-Bin Woo ... |
| title_fullStr | Management of the oncologic patient guest eds. Sook-Bin Woo ... |
| title_full_unstemmed | Management of the oncologic patient guest eds. Sook-Bin Woo ... |
| title_short | Management of the oncologic patient |
| title_sort | management of the oncologic patient |
| topic | Cancer Complications Cancer Treatment Dentistry Head and Neck Neoplasms Head Cancer Mouth Neoplasms Mouth Cancer Neck Cancer Neoplasms complications Neoplasms therapy Krebskranker (DE-588)4032913-6 gnd Zahnärztliche Behandlung (DE-588)4190487-4 gnd |
| topic_facet | Cancer Complications Cancer Treatment Dentistry Head and Neck Neoplasms Head Cancer Mouth Neoplasms Mouth Cancer Neck Cancer Neoplasms complications Neoplasms therapy Krebskranker Zahnärztliche Behandlung Aufsatzsammlung |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=016395858&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| volume_link | (DE-604)BV000003657 |
| work_keys_str_mv | AT woosookbin managementoftheoncologicpatient |