Application of stem cell markers in search for neoplastic germ cells in dysgenetic gonads, extragonadal tumours, and in semen of infertile men:
Gespeichert in:
| 1. Verfasser: | |
|---|---|
| Format: | Buch |
| Sprache: | English |
| Veröffentlicht: |
Copenhagen
Univ. of Copenhagen, Faculty of Health Sciences
2008
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| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | Zugl.: København, Univ., Diss., 2007 |
| Beschreibung: | getr. Zählung |
| ISBN: | 9788799237500 |
Internformat
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| 100 | 1 | |a Engel Høi-Hansen, Christina |e Verfasser |4 aut | |
| 245 | 1 | 0 | |a Application of stem cell markers in search for neoplastic germ cells in dysgenetic gonads, extragonadal tumours, and in semen of infertile men |c Christina Engel Høi-Hansen |
| 264 | 1 | |a Copenhagen |b Univ. of Copenhagen, Faculty of Health Sciences |c 2008 | |
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Datensatz im Suchindex
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| adam_text | INDEX
Acknowledgments 4
Summary 5
Introduction 6
Classification and historical background 6
Histological diagnosis of testicular carcinoma in situ 7
Dysgenetic features in testicular tissue harbouring carcinoma in situ 8
Recent knowledge on the carcinoma in situ gene-expression profile 10
Carcinoma in situ markers: immunohistochemistry and mutation analysis 12
Non-invasive detection methods for carcinoma in situ 15
Imaging techniques including ultrasound 16
Use of markers in semen of infertile males and testicular germ cell tumour patients 16
Molecular serum markers of testicular germ cell tumours 19
Germ cell tumours express similar markers irrespective of localisation 21
Summary and perspectives 24
References 26
Dansk resume 40
Included publications:
Paper 1 41
Hoei-Hansen CE. Holm M, Rajpert-De Meyts E, Skakkebaek NE. (2003) Histological evidence of testicular
dysgenesis in contralateral biopsies from 218 patients with testicular germ cell cancer. J Pathol, 200, 370-4
Paper 2 47
Holm M, Hoei-Hansen CE. Rajpert-De Meyts E, Skakkebask NE. (2003) Increased risk of carcinoma in situ
in testicular germ cell cancer patients with ultrasonic microlithiasis in the contralateral testicle. J Urol, 170, 1163-7
Paper 3 53
Hoei-Hansen CE. Nielsen JE, Almstrup K, Hansen MA, Skakkebaek NE, Rajpert-De Meyts E, Letters H. (2004)
Identification of genes differentially expressed in testes containing carcinoma in situ. Mol Hum Reprod, 10, 423-31
Paper 4 63
Almstrup K, Hoei-Hansen CE. Wirkner U, Blake J, Schwager C, Ansorge W, Nielsen JE, Skakkebaek NE,
Rajpert-De Meyts E, Letters H. (2004) Embryonic stem cell-like features of testicular carcinoma in situ revealed
by genome-wide gene expression profiling. Cancer Res, 64, 4736-43
Paper 5 73
Hoei-Hansen CE. Nielsen JE, Almstrup K, Brask Sonne S, Graem N, Skakkebaek NE, Leffers H, Rajpert-De
Meyts E. (2004) Transcription factor AP-2y is a developmentally regulated marker of testicular carcinoma in
situ and germ cell tumors. Clin Cancer Res, 10, 8521-30
Paper 6 85
Hoei-Hansen CE. Rajpert-De Meyts E, Carlsen E, Almstrup K, Leffers H, Skakkebaek NE. (2005) A subfertile
patient diagnosed with testicular carcinoma in situ by immunocytological staining for AP-2y in semen samples.
Hum Reprod. 20, 579-82
Paper 7 91
Hoei-Hansen CE. Almstrup K, Nielsen JE, Brask Sonne S, Graem N, Skakkebaek NE, Leffers H, Rajpert-De
Meyts. (2005) Stem cell pluripotency factor NANOG is expressed in human fetal gonocytes, testicular carcinoma
in situ and germ cell tumours. Histopathology, 47, 48-56
Paper 8 101
Hoei-Hansen CE, Sehested A, Juhler M, Lau Y-F C, Skakkebaek NE, Laursen H, Rajpert-De Meyts (2006)
New evidence for origin of intracranial germ cell tumours from primordial germ cells: Expression of pluripotency
and cell differentiation markers. J Pathol, 209, 25-33
Paper9 Ill
Brask Sonne S*, Hoei-Hansen CE*. Nielsen JE, Herlihy A, Andersson A-M, Almstrup K, Daugaard G, Skakkebaek
NE, Leffers H, Rajperts-De Meyts. (2006) Differential expression of CDH1 (E-cadherin) mRNA and protein in
testicular carcinoma in situ, and assessment of serum CDH1 in overt germ cell tumours APMIS, 114, 549-58
Paper 10 123
Hoei-Hansen CE. Carlsen E, Jorgensen N, Leffers H, Skakkebaek NE, Rajpert-De Meyts E. (2007) Towards a
non-invasive method for early detection of testicular neoplasia in semen samples by identification of foetal germ
cell-specific markers Hum Reprod, 22, 167-73
Paper 11 131
Hoei-Hansen CE . Kraggerud SM*, Abeler V, Kaem J, Rajpert-De Meyts E, Lothe RA. (2007) Ovarian dysgerminomas
are characterized by frequent KIT mutations and abundant expression of pluripotency markers Mol Cancer, 6, 12
These authors contributed equally.
|
| adam_txt |
INDEX
Acknowledgments 4
Summary 5
Introduction 6
Classification and historical background 6
Histological diagnosis of testicular carcinoma in situ 7
Dysgenetic features in testicular tissue harbouring carcinoma in situ 8
Recent knowledge on the carcinoma in situ gene-expression profile 10
Carcinoma in situ markers: immunohistochemistry and mutation analysis 12
Non-invasive detection methods for carcinoma in situ 15
Imaging techniques including ultrasound 16
Use of markers in semen of infertile males and testicular germ cell tumour patients 16
Molecular serum markers of testicular germ cell tumours 19
Germ cell tumours express similar markers irrespective of localisation 21
Summary and perspectives 24
References 26
Dansk resume 40
Included publications:
Paper 1 41
Hoei-Hansen CE. Holm M, Rajpert-De Meyts E, Skakkebaek NE. (2003) Histological evidence of testicular
dysgenesis in contralateral biopsies from 218 patients with testicular germ cell cancer. J Pathol, 200, 370-4
Paper 2 47
Holm M, Hoei-Hansen CE. Rajpert-De Meyts E, Skakkebask NE. (2003) Increased risk of carcinoma in situ
in testicular germ cell cancer patients with ultrasonic microlithiasis in the contralateral testicle. J Urol, 170, 1163-7
Paper 3 53
Hoei-Hansen CE. Nielsen JE, Almstrup K, Hansen MA, Skakkebaek NE, Rajpert-De Meyts E, Letters H. (2004)
Identification of genes differentially expressed in testes containing carcinoma in situ. Mol Hum Reprod, 10, 423-31
Paper 4 63
Almstrup K, Hoei-Hansen CE. Wirkner U, Blake J, Schwager C, Ansorge W, Nielsen JE, Skakkebaek NE,
Rajpert-De Meyts E, Letters H. (2004) Embryonic stem cell-like features of testicular carcinoma in situ revealed
by genome-wide gene expression profiling. Cancer Res, 64, 4736-43
Paper 5 73
Hoei-Hansen CE. Nielsen JE, Almstrup K, Brask Sonne S, Graem N, Skakkebaek NE, Leffers H, Rajpert-De
Meyts E. (2004) Transcription factor AP-2y is a developmentally regulated marker of testicular carcinoma in
situ and germ cell tumors. Clin Cancer Res, 10, 8521-30
Paper 6 85
Hoei-Hansen CE. Rajpert-De Meyts E, Carlsen E, Almstrup K, Leffers H, Skakkebaek NE. (2005) A subfertile
patient diagnosed with testicular carcinoma in situ by immunocytological staining for AP-2y in semen samples.
Hum Reprod. 20, 579-82
Paper 7 91
Hoei-Hansen CE. Almstrup K, Nielsen JE, Brask Sonne S, Graem N, Skakkebaek NE, Leffers H, Rajpert-De
Meyts. (2005) Stem cell pluripotency factor NANOG is expressed in human fetal gonocytes, testicular carcinoma
in situ and germ cell tumours. Histopathology, 47, 48-56
Paper 8 101
Hoei-Hansen CE, Sehested A, Juhler M, Lau Y-F C, Skakkebaek NE, Laursen H, Rajpert-De Meyts (2006)
New evidence for origin of intracranial germ cell tumours from primordial germ cells: Expression of pluripotency
and cell differentiation markers. J Pathol, 209, 25-33
Paper9 Ill
Brask Sonne S*, Hoei-Hansen CE*. Nielsen JE, Herlihy A, Andersson A-M, Almstrup K, Daugaard G, Skakkebaek
NE, Leffers H, Rajperts-De Meyts. (2006) Differential expression of CDH1 (E-cadherin) mRNA and protein in
testicular carcinoma in situ, and assessment of serum CDH1 in overt germ cell tumours APMIS, 114, 549-58
Paper 10 123
Hoei-Hansen CE. Carlsen E, Jorgensen N, Leffers H, Skakkebaek NE, Rajpert-De Meyts E. (2007) Towards a
non-invasive method for early detection of testicular neoplasia in semen samples by identification of foetal germ
cell-specific markers Hum Reprod, 22, 167-73
Paper 11 131
Hoei-Hansen CE'. Kraggerud SM*, Abeler V, Kaem J, Rajpert-De Meyts E, Lothe RA. (2007) Ovarian dysgerminomas
are characterized by frequent KIT mutations and abundant expression of pluripotency markers Mol Cancer, 6, 12
These authors contributed equally. |
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| spelling | Engel Høi-Hansen, Christina Verfasser aut Application of stem cell markers in search for neoplastic germ cells in dysgenetic gonads, extragonadal tumours, and in semen of infertile men Christina Engel Høi-Hansen Copenhagen Univ. of Copenhagen, Faculty of Health Sciences 2008 getr. Zählung txt rdacontent n rdamedia nc rdacarrier Zugl.: København, Univ., Diss., 2007 Stammzelle (DE-588)4665329-6 gnd rswk-swf Marker (DE-588)4037588-2 gnd rswk-swf Keimzelltumor (DE-588)4796842-4 gnd rswk-swf (DE-588)4113937-9 Hochschulschrift gnd-content Keimzelltumor (DE-588)4796842-4 s Stammzelle (DE-588)4665329-6 s Marker (DE-588)4037588-2 s DE-604 HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=016356357&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Engel Høi-Hansen, Christina Application of stem cell markers in search for neoplastic germ cells in dysgenetic gonads, extragonadal tumours, and in semen of infertile men Stammzelle (DE-588)4665329-6 gnd Marker (DE-588)4037588-2 gnd Keimzelltumor (DE-588)4796842-4 gnd |
| subject_GND | (DE-588)4665329-6 (DE-588)4037588-2 (DE-588)4796842-4 (DE-588)4113937-9 |
| title | Application of stem cell markers in search for neoplastic germ cells in dysgenetic gonads, extragonadal tumours, and in semen of infertile men |
| title_auth | Application of stem cell markers in search for neoplastic germ cells in dysgenetic gonads, extragonadal tumours, and in semen of infertile men |
| title_exact_search | Application of stem cell markers in search for neoplastic germ cells in dysgenetic gonads, extragonadal tumours, and in semen of infertile men |
| title_exact_search_txtP | Application of stem cell markers in search for neoplastic germ cells in dysgenetic gonads, extragonadal tumours, and in semen of infertile men |
| title_full | Application of stem cell markers in search for neoplastic germ cells in dysgenetic gonads, extragonadal tumours, and in semen of infertile men Christina Engel Høi-Hansen |
| title_fullStr | Application of stem cell markers in search for neoplastic germ cells in dysgenetic gonads, extragonadal tumours, and in semen of infertile men Christina Engel Høi-Hansen |
| title_full_unstemmed | Application of stem cell markers in search for neoplastic germ cells in dysgenetic gonads, extragonadal tumours, and in semen of infertile men Christina Engel Høi-Hansen |
| title_short | Application of stem cell markers in search for neoplastic germ cells in dysgenetic gonads, extragonadal tumours, and in semen of infertile men |
| title_sort | application of stem cell markers in search for neoplastic germ cells in dysgenetic gonads extragonadal tumours and in semen of infertile men |
| topic | Stammzelle (DE-588)4665329-6 gnd Marker (DE-588)4037588-2 gnd Keimzelltumor (DE-588)4796842-4 gnd |
| topic_facet | Stammzelle Marker Keimzelltumor Hochschulschrift |
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