Drug transporters: molecular characterization and role in drug disposition
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
Hoboken, NJ
Wiley-Interscience
2007
|
| Schriftenreihe: | Wiley series in drug discovery and development
|
| Schlagworte: | |
| Online-Zugang: | Contributor biographical information Publisher description lizenzfrei Inhaltsverzeichnis |
| Beschreibung: | Literaturangaben |
| Beschreibung: | XVI, 889 S. Ill., graph. Darst. 25 cm |
| ISBN: | 0471784915 9780471784913 |
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Datensatz im Suchindex
| _version_ | 1804137242885619712 |
|---|---|
| adam_text | CONTENTS
Contributors ix
Preface xv
1 Overview of Drug Transporter Families 1
Guofeng You and Marilyn E. Morris
2 Organic Cation Transporters 11
Thomas J. Urban and Kathleen M. Giacomini
3 Organic Cation/Carnitine Transporters 35
Ijaz A. Qureshi, Ihsan Elimrani, Ernest Seidman, and Grant Mitchell
4 Organic Anion Transporters 51
Megha Nagle, David M. Truong, Vibha Bhatnagar, Gregory Kaler,
Kevin T. Bush, Wei Wu, Satish A. Eraly, and Sanjay K. Nigam
5 Organic Anion Transporting Polypeptides 75
Rommel G. Tirona and Richard B. Kim
6 Mammalian Oligopeptide Transporters 105
Stephen M. Carl, Dea Herrera Ruiz, Rajinder K. Bhardwaj,
Olafur Gudmundsson, and Gregory T. Knipp
7 Monocarboxylate Transporters 147
Justin A. Spanier and Lester R. Drewes
8 Nucleoside Transporters: CNTs and ENTs 171
Li Xia, Mingyan Zhou, and Joanne Wang
v
vi CONTENTS
9 Bile Acid Transporters 201
Jyrki J. Eloranta and Gerd A. Kullak Ublick
10 Multidrug Resistance Protein: P Glycoprotein 223
Frances J. Shawm
11 Multidrug Resistance Proteins of the ABCC Subfamily 263
Anne T. Nies, Maria Rius, and Dietrich Keppler
12 Breast Cancer Resistance Protein 319
Robert W. Robey, Orsolya Polgar, John Deeken, Kenneth K. W. To,
and Susan E. Bates
13 Drug Transport in the Liver 359
Pieter Annaert, Brandon Swift, Jin Kyung Lee, and Kim L R. Brouwer
14 Drug Transport in the Brain 411
Patrick T. Ronaldson, Karlo Babakhanian, and Reina Bendayan
15 Drug Transport in the Kidney 463
Naohiko Anzai and Hitoshi Endou
16 Drug Transporters in the Intestine 495
Yarning Su and Patrick J. Sinko
17 Regulation of Drug Transporter Activity 517
Mei Hong and Guofeng You
18 Experimental Approaches to the Study of Drug
Transporters 533
Yoshiyuki Kubo, Yukio Kato, and Akira Tsuji
19 In Vitro In Vivo Scale up of Drug Transport Activities 557
Kazuya Maeda and Yuichi Sugiyama
20 Age and Gender Related Differences in Xenobiotic
Transporter Expression 589
Curtis D. Klaassen and Xingguo Cheng
21 Polymorphisms of Drug Transporters and Clinical
Relevance 619
Leslie W. Chinn, Jason M. Gow, and Deanna L. Kroetz
22 Diet/Nutrient Interactions with Drug Transporters 665
Xiaodong Wang and Marilyn E. Morris
23 Interplay of Drug Transporters and Enzymes on Hepatic
Drug Processing 709
K. Sandy Pang, Huadong Sun, and Shanjun Liu
CONTENTS vii
24 Clinical Relevance: Drug Drug Interactions,
Pharmacokinetics, Pharmacodynamics, and Toxicity 747
Serena Marchetti, Roberto Mazzanti, Jos H. Beijnen, and
Jan H. M. Schellens
Index 881
|
| adam_txt |
CONTENTS
Contributors ix
Preface xv
1 Overview of Drug Transporter Families 1
Guofeng You and Marilyn E. Morris
2 Organic Cation Transporters 11
Thomas J. Urban and Kathleen M. Giacomini
3 Organic Cation/Carnitine Transporters 35
Ijaz A. Qureshi, Ihsan Elimrani, Ernest Seidman, and Grant Mitchell
4 Organic Anion Transporters 51
Megha Nagle, David M. Truong, Vibha Bhatnagar, Gregory Kaler,
Kevin T. Bush, Wei Wu, Satish A. Eraly, and Sanjay K. Nigam
5 Organic Anion Transporting Polypeptides 75
Rommel G. Tirona and Richard B. Kim
6 Mammalian Oligopeptide Transporters 105
Stephen M. Carl, Dea Herrera Ruiz, Rajinder K. Bhardwaj,
Olafur Gudmundsson, and Gregory T. Knipp
7 Monocarboxylate Transporters 147
Justin A. Spanier and Lester R. Drewes
8 Nucleoside Transporters: CNTs and ENTs 171
Li Xia, Mingyan Zhou, and Joanne Wang
v
vi CONTENTS
9 Bile Acid Transporters 201
Jyrki J. Eloranta and Gerd A. Kullak Ublick
10 Multidrug Resistance Protein: P Glycoprotein 223
Frances J. Shawm
11 Multidrug Resistance Proteins of the ABCC Subfamily 263
Anne T. Nies, Maria Rius, and Dietrich Keppler
12 Breast Cancer Resistance Protein 319
Robert W. Robey, Orsolya Polgar, John Deeken, Kenneth K. W. To,
and Susan E. Bates
13 Drug Transport in the Liver 359
Pieter Annaert, Brandon Swift, Jin Kyung Lee, and Kim L R. Brouwer
14 Drug Transport in the Brain 411
Patrick T. Ronaldson, Karlo Babakhanian, and Reina Bendayan
15 Drug Transport in the Kidney 463
Naohiko Anzai and Hitoshi Endou
16 Drug Transporters in the Intestine 495
Yarning Su and Patrick J. Sinko
17 Regulation of Drug Transporter Activity 517
Mei Hong and Guofeng You
18 Experimental Approaches to the Study of Drug
Transporters 533
Yoshiyuki Kubo, Yukio Kato, and Akira Tsuji
19 In Vitro In Vivo Scale up of Drug Transport Activities 557
Kazuya Maeda and Yuichi Sugiyama
20 Age and Gender Related Differences in Xenobiotic
Transporter Expression 589
Curtis D. Klaassen and Xingguo Cheng
21 Polymorphisms of Drug Transporters and Clinical
Relevance 619
Leslie W. Chinn, Jason M. Gow, and Deanna L. Kroetz
22 Diet/Nutrient Interactions with Drug Transporters 665
Xiaodong Wang and Marilyn E. Morris
23 Interplay of Drug Transporters and Enzymes on Hepatic
Drug Processing 709
K. Sandy Pang, Huadong Sun, and Shanjun Liu
CONTENTS vii
24 Clinical Relevance: Drug Drug Interactions,
Pharmacokinetics, Pharmacodynamics, and Toxicity 747
Serena Marchetti, Roberto Mazzanti, Jos H. Beijnen, and
Jan H. M. Schellens
Index 881 |
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| spelling | Drug transporters molecular characterization and role in drug disposition ed. by Guofeng You ... Hoboken, NJ Wiley-Interscience 2007 XVI, 889 S. Ill., graph. Darst. 25 cm txt rdacontent n rdamedia nc rdacarrier Wiley series in drug discovery and development Literaturangaben Carrier proteins Drug carriers (Pharmacy) Biological Transport physiology Membrane Transport Proteins physiology Pharmacokinetics Membrantransport (DE-588)4038575-9 gnd rswk-swf Arzneimittel (DE-588)4003115-9 gnd rswk-swf Carrier-Proteine (DE-588)4213127-3 gnd rswk-swf (DE-588)4173536-5 Patentschrift gnd-content Carrier-Proteine (DE-588)4213127-3 s Arzneimittel (DE-588)4003115-9 s Membrantransport (DE-588)4038575-9 s 1\p DE-604 You, Guofeng Sonstige oth http://www.loc.gov/catdir/enhancements/fy0739/2006038880-b.html Contributor biographical information lizenzfrei http://www.loc.gov/catdir/enhancements/fy0739/2006038880-d.html Publisher description lizenzfrei http://www.loc.gov/catdir/toc/ecip075/2006038880.html lizenzfrei Inhaltsverzeichnis HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=016226451&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
| spellingShingle | Drug transporters molecular characterization and role in drug disposition Carrier proteins Drug carriers (Pharmacy) Biological Transport physiology Membrane Transport Proteins physiology Pharmacokinetics Membrantransport (DE-588)4038575-9 gnd Arzneimittel (DE-588)4003115-9 gnd Carrier-Proteine (DE-588)4213127-3 gnd |
| subject_GND | (DE-588)4038575-9 (DE-588)4003115-9 (DE-588)4213127-3 (DE-588)4173536-5 |
| title | Drug transporters molecular characterization and role in drug disposition |
| title_auth | Drug transporters molecular characterization and role in drug disposition |
| title_exact_search | Drug transporters molecular characterization and role in drug disposition |
| title_exact_search_txtP | Drug transporters molecular characterization and role in drug disposition |
| title_full | Drug transporters molecular characterization and role in drug disposition ed. by Guofeng You ... |
| title_fullStr | Drug transporters molecular characterization and role in drug disposition ed. by Guofeng You ... |
| title_full_unstemmed | Drug transporters molecular characterization and role in drug disposition ed. by Guofeng You ... |
| title_short | Drug transporters |
| title_sort | drug transporters molecular characterization and role in drug disposition |
| title_sub | molecular characterization and role in drug disposition |
| topic | Carrier proteins Drug carriers (Pharmacy) Biological Transport physiology Membrane Transport Proteins physiology Pharmacokinetics Membrantransport (DE-588)4038575-9 gnd Arzneimittel (DE-588)4003115-9 gnd Carrier-Proteine (DE-588)4213127-3 gnd |
| topic_facet | Carrier proteins Drug carriers (Pharmacy) Biological Transport physiology Membrane Transport Proteins physiology Pharmacokinetics Membrantransport Arzneimittel Carrier-Proteine Patentschrift |
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