Verfügbarkeit: Pediatric critical care medicine

Pediatric critical care medicine: basic science and clinical evidence

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Format:	Buch
Sprache:	English
Veröffentlicht:	London Springer 2007
Schlagworte:	Child Critical Care Critical Illness > therapy Infant Pediatric emergencies Pediatric intensive care Pediatrics Kind Intensivmedizin
Online-Zugang:	Inhaltstext Inhaltsverzeichnis
Beschreibung:	XXXVIII, 1805 S. zahlr. Ill. und graph. Darst.
ISBN:	9781846284632

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245	1	0	\|a Pediatric critical care medicine \|b basic science and clinical evidence \|c Derek S. Wheeler ... (ed.)
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Datensatz im Suchindex

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adam_text	Contents Foreword by Thomas P. Green and George Lister ................................... v Preface: Promises to Keep .................................................... vii Acknowledgments ............................................................. ix Contributors ................................................................... xix A Tribute to Peter J. Safar, MD by John J. Dowries .................................. xxxvii Section I The Practice of Pediatrie Critical Care Medicine 1 Development of Pediatrie Critical Care Medicine — How Did We Get Here and Why? ........................................................... 3 John J. Dowries 2 Epidemiology of Critical Illness ............................................ 31 R. Scott Watson and Mary E. Hartman 3 Ethics in the Pediatrie Intensive Care Unit .................................. 36 K. Sarah Hoehn and Robert M. Nelson 4 The Patient s Family in the Pediatrie Intensive Care Unit ..................... 43 SolJ. Goldstein and I. David Todres 5 Scoring Systems in Critical Care ........................................... 51 Thomas J. Cholis, III and Murray M. Pollack 6 Outcomes and Quality: Definitions, Assessment, and Analysis ................ 55 Susan L. Bratton and James P. Marcin 7 Pediatrie Intensive Care Unit Administration ............................... 63 Lorry R. Frankéi 8 Nursing Care in the Pediatrie Intensive Care Unit ............................ 68 Franco A. Carnevale 9 The Physician-Scientist in the Pediatrie Intensive Care Unit .................. 72 Thomas P. Shanley 10 Resident and Nurse Education in the Pediatrie Intensive Care Unit ............ 77 Girish G. Deshpande, Gwen Lombard, and Adalberto Torres, Jr. 11 Evidence-Based Medicine in the Pediatrie Intensive Care Unit ................. 82 Adrienne G. Randolph 12 Patient Safety in the Pediatrie Intensive Care Unit ........................... 88 David C. Stockwell and Anthony D. Slonim 13 Pediatrie Critical Care in Developing Countries ............................. 94 Gregory L. Stidham and William M. Novick 14 The Pediatrie Intensive Care Unit of the Future: Technological Advances in Pediatrie Critical Care Medicine ........................................... 102 Kenneth Tegtmeyer XI Contents Section II The Science of Pediatrie Critical Care Medicine 15 Molecular Biology in the Pediatrie Intensive Care Unit ....................... Ш Lesley A. Doughty 16 Genetic Polymorphisms in Critical Care and Illness .......................... 134 Mary K. Dahmer and Michael W. Quasney 17 Signal Transduction Pathways in Critical Illness and Injury ................... 150 Timothy T. Cornell and Thomas P. Shanley 18 Proinflammatory and Antiinflammatory Mediators in Critical Illness .......... 159 Daniel G. Remick 19 Endogenous Cytoprotective Mechanisms .................................... 166 Hector R. Wong 20 Ischemia-Reperfusion Injury .............................................. 175 Basilia Zingarelli Section III Resuscitation and Stabilization of the Critically 111 Child 21 Emergency Medical Services for Children ................................... 189 Derek S. Wheeler and Tom LeMaster 22 Pediatrie Cardiopulmonary Resuscitation ................................... 202 Vinay M. Nadkarni and Robert A. Berg 23 Supplemental Oxygen and Bag-Valve-Mask Ventilation ....................... 217 Patricia Abboud, Jennifer Raake, and Derek S. Wheeler 24 Assessment and Management of the Pediatrie Airway ........................ 223 Derek S. Wheeler, James P. Spaeth, Renuka Mehta, Suriyanarayana P. Hariprakash, and Peter N. Cox 25 Vascular Access .......................................................... 253 Jennifer Kaplan and Richard J. Brilli 26 Shock: An Overview ...................................................... 274 Joseph A. Cardilo, Derek S. Wheeler, Neil W. Kooy, and Thomas P. Shanley 27 Acute Respiratory Failure ................................................. 299 Jennifer L. Turi and Ira M. Cheifetz 28 Pediatrie Transport Medicine .............................................. 308 Derek S. Wheeler and W. Bradley Poss 29 Withdrawal of Life Support ................................................ 320 Kathleen L. Meert and Ashok P. Sarnaik 30 Brain Death .............................................................. 324 Sam D. Shemie 31 The Pathophysiology of Brain Death and Care of the Potential Organ Donor ___ 333 Sam D. Shemie Section IV The Respiratory Tract in Critical Illness and Injury 32 Respiratory Physiology .................................................... 349 Howard E. Jeffries ana Lynn D. Martin 33 Disorders of the Pediatrie Chest ............................................ 361 Margaret A. Chase and Derek S. Wheeler 34 Respiratory Monitoring ................................................... 376 John Marcum and Christopher J.L. Newth 35 Bronchoscopy in the Pediatrie Intensive Care Unit ........................... 390 Robert E. Wood 36 Acute Lung Injury and Acute Respiratory Distress Syndrome ................. 395 Michael Vish and Thomas P. Shanley Contents xiii 37 Mechanical Ventilation ................................................... 412 Alik Kornecki and Brian P. Kavanagh 38 Ventilator-Induced Lung Injury ............................................ 426 Shinya Tsuchida and Brian P. Kavanagh 39 Prone Positioning ........................................................ 432 Nilesh M. Mehta and Martha A.Q. Curley 40 High-Frequency Oscillatory Ventilation ..................................... 442 Kathleen M. Ventre and John H. Arnold 41 Pulmonary Surfactant: Biology and Therapy ................................ 453 Douglas F. Willson, Patricia R. Chess, Zhengdong Wang, and Robert H. Nötter 42 Nitric Oxide ............................................................. 467 Emily L. Dobyns and Eva N. Grayck 43 Extracorporeal Life Support for Children With Acute Respiratory Failure ...... 473 Heidi J. Dalton and Angela T. Wratney 44 Diseases of the Upper Respiratory Tract .................................... 485 Renuka Mehta, Suriyanarayana P. Hariprakash, Peter N. Cox, and Derek S. Wheeler 45 Congenital Airway and Respiratory Tract Anomalies ......................... 506 Michael J. Rutter 46 Status Asthmaticus ....................................................... 512 Derek S. Wheeler, Kristen Page, and Thomas P. Shanley 47 Bronchiolitis ............................................................. 537 Ann Marie LeVine 48 Pneumonia and Empyema ................................................. 544 Imad Y. Haddad and David N. Cornfield 49 Pediatric Lung Transplantation ............................................ 554 David N. Cornfield and Imad Y. Haddad 50 Neuromuscular Respiratory Failure ........................................ 560 Margaret F. Guill and Thomas P. Shanley 51 Diseases of the Pulmonary Vascular System ................................. 570 Peter Oishi and Jeffrey R. Fineman Section V The Cardiovascular System in Critical Illness and Injury 52 Developmental Cardiac Physiology ......................................... 591 Keith С Kocis, Ana Lia Gradano, and Jon N. Mellones 53 Hemodynamic Monitoring ................................................ 602 Shane M. Tibby 54 Cardiopulmonary Interactions ............................................. 622 Desmond J. Bohn 55 Echocardiography in the Pediatrie Critical Care Setting ...................... 644 William L. Border, Erik С Michelfelder, Kan Hor, and Dianna S. Meredith 56 Cardiac Catheterization in the Pediatric Critical Care Setting ................. 651 Russell Hirsch and Robert H. Beekman, III 57 Introduction to Congenital Heart Disease: Nomenclature and Classification ........................................................ 665 James D. St. Louis 58 Palliative Procedures ..................................................... 668 Mark A. Scheurer and Andrew M. Atz 59 Congenital Heart Disease: Left-to-Right Shunt Lesions ....................... 672 Derek S. Wheeler, James D. St. Louis, and Catherine L. Dent x¡v Contents 60 Congenital Heart Disease: Cyanotic Lesions with Decreased Pulmonary Blood Flow ............................................................... 679 John M. Costello and Peter С Laussen 61 Congenital Heart Disease: Left Ventricular Outflow Tract Obstruction ......... 692 John R. Charpie, Dennis С Crowley, and Joseph N. Graziano 62 Congenital Heart Disease: Cyanotic Lesions with Increased Pulmonary Blood Flow ............................................................... 700 Peter B. Manning and James D. St. Louis 63 Single-Ventricle Lesions ................................................... 706 Steven M. Schwartz, David P. Nelson, Catherine L. Dent, Ndidi L. Musa, and Derek S. Wheeler 64 Vascular Rings and Associated Malformations .............................. 716 Carl L. Backer, Constantine Mavroudis, and Lauren D. Holinger 65 Cardiopulmonary Bypass ................................................. 727 Kelly M. McLean, John P. Lombardi, and Jeffrey M. Pearl 66 Pediatric Myocardial Protection ........................................... 742 Jeffrey M. Pearl, Jodie Y. Duffy, and Kelly M. McLean 67 Postoperative Care of the Pediatric Cardiac Surgical Patient .................. 752 Catherine L. Dent and Steven M. Schwartz 68 Mechanical Support of the Cardiovascular System: Extracorporeal Life Support/Extracorporeal Membrane Oxygénation and Ventricular Assist Devices ............................................................ 765 Heidi J. Dalton and Brian W. Duncan 69 Mechanical Support of the Cardiovascular System: Intraaortic Balloon Pumping in Children ..................................................... 777 L. LuAnn Minich and John A. Hawkins 70 Arrhythmias ............................................................. 785 Timothy K. Knilans 71 Inflammatory Diseases of the Heart and Pericardium: Infective Endocarditis and Kawasaki Disease ........................................ 798 Michael H. Gewitz and Gary M. Satou 72 Inflammatory Diseases of the Heart and Pericardium: Dilated Cardiomyopathy and Myocarditis .......................................... 808 Henry B. Wiles, Neil W. Kooy, and Derek S. Wheeler 73 Diseases of the Pericardium ............................................... 821 Michael H. Gewitz, Gary M. Satou, and Derek S. Wheeler 74 Management of Hypertension in the Pediatrie Intensive Care Unit ............. 828 Marianne N. Majdalani and Neil W. Kooy 75 Heart Transplantation .................................................... 841 Shamel Abd-Allah and Paul A. Checchia Section VI The Central Nervous System in Critical Illness and Injury 76 Central Nervous System Monitoring ........................................ 865 Michael J. Bell and Taeun Chang 77 Molecular Biology of Brain Injury .......................................... 872 Michael J. Whalen, Phoebe Yager, EngH. Lo, Josephine Lok, and Natan Noviski 78 Pediatrie Intensive Care Unit Management of Neurosurgical Diseases .......... 884 Darlene A. Lobel, Mark R. Lee, and Ann-Christine Duhaime 79 Tumors of the Central Nervous System ..................................... 894 Robert Tamburro, Raymond С Barfield, and Amar Gajjar Contents xv 80 Intracranial Hypertension................................................. 902 Steven G. Kérnie and Samuel M. Lehman 81 Nonaccidental Trauma and Shaken Baby Syndrome .......................... 916 Robert С Tasker 82 Evaluation of Coma ....................................................... 924 David J. Michelson and Stephen Ashwal 83 Hypoxie Ischemic Encephalopathy After Cardiorespiratory Arrest ............. 935 Dermot R. Doherty and fames S. Hutchison 84 Toxic and Metabolic Encephalopathies ..................................... 947 Ashok P. Sarnaik and Kathleen L. Meert 85 Infections of the Central Nervous System ................................... 956 Simon Nadel 86 Status Epilepticus ........................................................ 977 Richard P.M. Chin and Rod С Scott 87 Diseases of the Peripheral Nervous System .................................. 990 Cecil D. Hahn and Brenda L. Banwell Section VII The Gastrointestinal Tract in Critical Illness and Injury 88 Gastrointestinal Bleeding ................................................. 1013 Renuka Mehta and Thomas P. Shanley 89 Acute Pancreatitis ........................................................ 1022 Raffaele Pezzali, Paola Tomassetti, Rosa Ceciliato, and Roberto Corinaldesi 90 Liver Failure in Infants and Children ....................................... 1027 Ann Б. Thompson 91 Pediatrie Liver Transplantation ............................................ 1040 Gregory M. Tiao and Frederick C. Ryckman 92 Perioperative Management of the Pediatrie Surgical Patient ................... 1054 David E. Carney, Frederick J. Rescorla, and Jay L. Grosfeld 93 Abdominal Compartment Syndrome in Children ............................ 1073 Gad Bar-Joseph and Raphael Beck 94 Nutritional Support of the Critically 111 Child ............................... 1079 Michael S.D. Agus and Tom Jaksic 95 Nutritional Assessment of the Critically 111 Child ............................ 1090 George Briassoulis Section VIII The Endocrine System in Critical Illness and Injury 96 Inborn Errors of Metabolism .............................................. 1103 Nancy Doan Leslie 97 Endocrine Emergencies ................................................... 1111 Michael Bigham, Jennifer Kaplan, Neil W. Kooy, and Derek S. Wheeler 98 Endocrine Disorders in the Pediatrie Intensive Care Unit ..................... 1125 Ruth Armano and Greet Van den Berghe Section IX Fluids and Electrolytes in Critical Illness and Injury 99 Renal Physiology ......................................................... 1143 Russell W. Chesney and Noel M. de los Santos 100 Electrolyte Disorders in the Pediatrie Intensive Care Unit ..................... 1156 Gabriel J. Hauser and Aaron F. Kulick Contents 101 Acid-Base Disorders in the Pediatrie Intensive Care Unit ..................... 1176 James D. Fortenberry, Kiran Hebbar, and Derek S. Wheeler 102 Renal Diseases in the Pediatrie Intensive Care Unit: Thrombotic Microangiopathy, Hemolytic Uremie Syndrome, and Thrombotic Thrombocytopenic Purpura ............................................... 1189 François Proulx and Vernon L. Tesh 103 Renal Disorders in the Pediatrie Intensive Care Unit: Glomerulonephritis and Nephrotic Syndrome ...................................................... 1204 Jen-Jar Lin and William E. Smoyer 104 Acute Renal Failure ....................................................... 1221 Mai T. Nguyen and John J. Bissler 105 Continuous Renal Replacement Therapy .................................... 1228 Kevin D. McBryde and Timothy E. Bunchman 106 Alternative Indications for Hemofiltration .................................. 1243 Joseph V. DiCarlo and Steven R. Alexander 107 Renal Transplantation .................................................... 1250 Coral D. Hanevold, James J. Wynn, and Luis A. Ortiz Section X Hematologic/Oncologic Problems in Critical Illness and Injury 108 Transfusion Medicine ..................................................... 1263 Jacques Lacroix, Marisa Tucci, France Gauvin, Baruch Toledano, and Heather Hume 109 Disorders of Blood Elements ............................................... 1281 Niranjan Kissoon 110 Coagulation, Anticoagulation, and Hemorrhage in the Intensive Care Setting ... 1296 Geoffrey M. Fleming, Monika Gupta, and Gail M. Annich 111 Catheter-Related Occlusion and Thrombosis ................................ 1313 Rânjit S. Chima and Brian R. Jacobs 111 Venous Tnromboembolic Disease and Pulmonary Embolism in Children ....... 1322 N. William Partila and Brian R. Jacobs 113 Care of the Oncology Patient in the Pediatrie Intensive Care Unit .............. 1332 Robert Tamburro, Raymond C. Barfield, Monika L. Metzger, Terrence L. Geiger, Sandy Call, and Kenneth W. Gow 114 Complications Requiring Critical Care Following Hematopoietic Stem Cell Transplantation ...................................................... 1355 Kenneth R. Cooke, Paul Richardson, and Gregory A. Yanik Section XI The Immune System in Critical Illness and Injury 115 Pharmacology of Imrmmosuppression ...................................... 1379 John F. Sommerauer 116 Primary and Secondary Immunodeficiencies ................................ 1405 Rajesh Aneja and Alexandre T. Rotta 117 Sepsis ................................................................... 1421 Jan A. Hazelzet, Gertjan J.A. Driessen, Patricia Abboud, Derek S. Wheeler, Thomas P. Shanley, and Hector R. Wong 118 Multiple Organ Dysfunction Syndrome ..................................... 1445 Katri Typpo and Michele Mariscalco 119 The Patient with the Human Immunodeficiency Virus in the Pediatrie Intensive Care Unit ....................................................... I457 Amisha Malhotra, Steven Choi, and Daniel A. Notterman Contents xvii 120 Nosocomial Infections in the Pediatrie Intensive Care Unit ................... 1472 Mark E. Rowin, Amit Vohra, and John С. Chrisłenson 121 Anaphylaxis ............................................................. 1486 Todd A. Levin, Cristina M. Mazzoni, and Dennis R. Ownby 122 Rheumatologic Disorders in the Pediatrie Intensive Care Unit ................. 1492 Steven W. Martin and Michael R. Anderson 123 Infectious Disease-Associated Syndromes ................................... 1511 Isaac Lazar and Clifford W. Bogue Section XII Trauma 124 Trauma Systems and Regionalization of Trauma Care ........................ 1523 Dennis R. Durbin and Michael L. Nance 125 Head and Neck Trauma ................................................... 1527 Lisa Grimaldi, Charles L. Schleien, Derek A. Bruce, Amanda Yaun, and Derek S. Wheeler 126 Dental Trauma ........................................................... 1545 William A. Greenhill and Murray Dock 127 Maxillofacial Trauma ..................................................... 1551 Likith V. Ready and Haithem Elhadi 128 Eye Trauma and Emergencies .............................................. 1558 Stephanie L . Goei, Heojeng Ooi, and Julian J. Nussbaum 129 Thoracic Trauma......................................................... 1565 Mindy В. Statter and Donald C. Liu 130 Abdominal Trauma....................................................... 1572 Rebeccah L. Brown 131 Genitourinary Trauma .................................................... 1579 jR. Guy Hudson and George W. Kaplan 132 Orthopedic Trauma....................................................... 1589 Charles T. Mehlman and Alvin ff. Crawford 133 Pediatrie Burns ........................................................... 1597 Grace Z. Mak, Steven R. Allen, and Richard J. Kagan Section XIII Pharmacology and Toxicology in the Pediatrie Intensive Care Unit 134 Introduction to Pharmacology ............................................. 1609 James A. Besunder and John Pope 135 Toxic Exposures: Diagnosis and Management ............................... 1621 Karen S. Powers, Jill M. Cholette, and Patricia Abboud 136 Sedation and Analgesia ................................................... 1642 Joseph D. Tobias 137 Procedural Sedation and Anesthesia ........................................ 1668 Stephen D. Playfor and Neil S. Morton 138 Neuromuscular Blockade .................................................. 1674 Nicholas B. Slamon, Mary С Theroux, and Andrew T. Cestarino, Jr. Section XIV Environmental Emergencies 139 Envenomations ........................................................... 1687 James Tibballs, Christopher P. Holstege, and Derek S. Wheeler 140 Drowning and Near-Drowning ............................................. 1706 Laura M. Ibsen xviii Contents 141 Heat Illness and Hypothermia ............................................. 1714 Lynne W. Coule and William Wiers 142 Malignant Hyperthermia .................................................. 1725 Richard E. Berlin and Paul]. Samuels 143 Principles of Mass Casualty and Disaster Medicine ........................... 1730 David Markenson, Gad Bar-Joseph, Michael Halberthal, and Derek S. Wheeler 144 An Overview of Chemical and Biologic Agents of Terrorism ................... 1743 Richard B. Schwartz, Phillip L. Coule, and David Markenson Index ......................................................................... 1765
adam_txt	Contents Foreword by Thomas P. Green and George Lister . v Preface: "Promises to Keep" . vii Acknowledgments . ix Contributors . xix A Tribute to Peter J. Safar, MD by John J. Dowries . xxxvii Section I The Practice of Pediatrie Critical Care Medicine 1 Development of Pediatrie Critical Care Medicine — How Did We Get Here and Why? . 3 John J. Dowries 2 Epidemiology of Critical Illness . 31 R. Scott Watson and Mary E. Hartman 3 Ethics in the Pediatrie Intensive Care Unit . 36 K. Sarah Hoehn and Robert M. Nelson 4 The Patient's Family in the Pediatrie Intensive Care Unit . 43 SolJ. Goldstein and I. David Todres 5 Scoring Systems in Critical Care . 51 Thomas J. Cholis, III and Murray M. Pollack 6 Outcomes and Quality: Definitions, Assessment, and Analysis . 55 Susan L. Bratton and James P. Marcin 7 Pediatrie Intensive Care Unit Administration . 63 Lorry R. Frankéi 8 Nursing Care in the Pediatrie Intensive Care Unit . 68 Franco A. Carnevale 9 The Physician-Scientist in the Pediatrie Intensive Care Unit . 72 Thomas P. Shanley 10 Resident and Nurse Education in the Pediatrie Intensive Care Unit . 77 Girish G. Deshpande, Gwen Lombard, and Adalberto Torres, Jr. 11 Evidence-Based Medicine in the Pediatrie Intensive Care Unit . 82 Adrienne G. Randolph 12 Patient Safety in the Pediatrie Intensive Care Unit . 88 David C. Stockwell and Anthony D. Slonim 13 Pediatrie Critical Care in Developing Countries . 94 Gregory L. Stidham and William M. Novick 14 The Pediatrie Intensive Care Unit of the Future: Technological Advances in Pediatrie Critical Care Medicine . 102 Kenneth Tegtmeyer XI Contents Section II The Science of Pediatrie Critical Care Medicine 15 Molecular Biology in the Pediatrie Intensive Care Unit . Ш Lesley A. Doughty 16 Genetic Polymorphisms in Critical Care and Illness . 134 Mary K. Dahmer and Michael W. Quasney 17 Signal Transduction Pathways in Critical Illness and Injury . 150 Timothy T. Cornell and Thomas P. Shanley 18 Proinflammatory and Antiinflammatory Mediators in Critical Illness . 159 Daniel G. Remick 19 Endogenous Cytoprotective Mechanisms . 166 Hector R. Wong 20 Ischemia-Reperfusion Injury . 175 Basilia Zingarelli Section III Resuscitation and Stabilization of the Critically 111 Child 21 Emergency Medical Services for Children . 189 Derek S. Wheeler and Tom LeMaster 22 Pediatrie Cardiopulmonary Resuscitation . 202 Vinay M. Nadkarni and Robert A. Berg 23 Supplemental Oxygen and Bag-Valve-Mask Ventilation . 217 Patricia Abboud, Jennifer Raake, and Derek S. Wheeler 24 Assessment and Management of the Pediatrie Airway . 223 Derek S. Wheeler, James P. Spaeth, Renuka Mehta, Suriyanarayana P. Hariprakash, and Peter N. Cox 25 Vascular Access . 253 Jennifer Kaplan and Richard J. Brilli 26 Shock: An Overview . 274 Joseph A. Cardilo, Derek S. Wheeler, Neil W. Kooy, and Thomas P. Shanley 27 Acute Respiratory Failure . 299 Jennifer L. Turi and Ira M. Cheifetz 28 Pediatrie Transport Medicine . 308 Derek S. Wheeler and W. Bradley Poss 29 Withdrawal of Life Support . 320 Kathleen L. Meert and Ashok P. Sarnaik 30 Brain Death . 324 Sam D. Shemie 31 The Pathophysiology of Brain Death and Care of the Potential Organ Donor _ 333 Sam D. Shemie Section IV The Respiratory Tract in Critical Illness and Injury 32 Respiratory Physiology . 349 Howard E. Jeffries ana Lynn D. Martin 33 Disorders of the Pediatrie Chest . 361 Margaret A. Chase and Derek S. Wheeler 34 Respiratory Monitoring . 376 John Marcum and Christopher J.L. Newth 35 Bronchoscopy in the Pediatrie Intensive Care Unit . 390 Robert E. Wood 36 Acute Lung Injury and Acute Respiratory Distress Syndrome . 395 Michael Vish and Thomas P. Shanley Contents xiii 37 Mechanical Ventilation . 412 Alik Kornecki and Brian P. Kavanagh 38 Ventilator-Induced Lung Injury . 426 Shinya Tsuchida and Brian P. Kavanagh 39 Prone Positioning . 432 Nilesh M. Mehta and Martha A.Q. Curley 40 High-Frequency Oscillatory Ventilation . 442 Kathleen M. Ventre and John H. Arnold 41 Pulmonary Surfactant: Biology and Therapy . 453 Douglas F. Willson, Patricia R. Chess, Zhengdong Wang, and Robert H. Nötter 42 Nitric Oxide . 467 Emily L. Dobyns and Eva N. Grayck 43 Extracorporeal Life Support for Children With Acute Respiratory Failure . 473 Heidi J. Dalton and Angela T. Wratney 44 Diseases of the Upper Respiratory Tract . 485 Renuka Mehta, Suriyanarayana P. Hariprakash, Peter N. Cox, and Derek S. Wheeler 45 Congenital Airway and Respiratory Tract Anomalies . 506 Michael J. Rutter 46 Status Asthmaticus . 512 Derek S. Wheeler, Kristen Page, and Thomas P. Shanley 47 Bronchiolitis . 537 Ann Marie LeVine 48 Pneumonia and Empyema . 544 Imad Y. Haddad and David N. Cornfield 49 Pediatric Lung Transplantation . 554 David N. Cornfield and Imad Y. Haddad 50 Neuromuscular Respiratory Failure . 560 Margaret F. Guill and Thomas P. Shanley 51 Diseases of the Pulmonary Vascular System . 570 Peter Oishi and Jeffrey R. Fineman Section V The Cardiovascular System in Critical Illness and Injury 52 Developmental Cardiac Physiology . 591 Keith С Kocis, Ana Lia Gradano, and Jon N. Mellones 53 Hemodynamic Monitoring . 602 Shane M. Tibby 54 Cardiopulmonary Interactions . 622 Desmond J. Bohn 55 Echocardiography in the Pediatrie Critical Care Setting . 644 William L. Border, Erik С Michelfelder, Kan Hor, and Dianna S. Meredith 56 Cardiac Catheterization in the Pediatric Critical Care Setting . 651 Russell Hirsch and Robert H. Beekman, III 57 Introduction to Congenital Heart Disease: Nomenclature and Classification . 665 James D. St. Louis 58 Palliative Procedures . 668 Mark A. Scheurer and Andrew M. Atz 59 Congenital Heart Disease: Left-to-Right Shunt Lesions . 672 Derek S. Wheeler, James D. St. Louis, and Catherine L. Dent x¡v Contents 60 Congenital Heart Disease: Cyanotic Lesions with Decreased Pulmonary Blood Flow . 679 John M. Costello and Peter С Laussen 61 Congenital Heart Disease: Left Ventricular Outflow Tract Obstruction . 692 John R. Charpie, Dennis С Crowley, and Joseph N. Graziano 62 Congenital Heart Disease: Cyanotic Lesions with Increased Pulmonary Blood Flow . 700 Peter B. Manning and James D. St. Louis 63 Single-Ventricle Lesions . 706 Steven M. Schwartz, David P. Nelson, Catherine L. Dent, Ndidi L. Musa, and Derek S. Wheeler 64 Vascular Rings and Associated Malformations . 716 Carl L. Backer, Constantine Mavroudis, and Lauren D. Holinger 65 Cardiopulmonary Bypass . 727 Kelly M. McLean, John P. Lombardi, and Jeffrey M. Pearl 66 Pediatric Myocardial Protection . 742 Jeffrey M. Pearl, Jodie Y. Duffy, and Kelly M. McLean 67 Postoperative Care of the Pediatric Cardiac Surgical Patient . 752 Catherine L. Dent and Steven M. Schwartz 68 Mechanical Support of the Cardiovascular System: Extracorporeal Life Support/Extracorporeal Membrane Oxygénation and Ventricular Assist Devices . 765 Heidi J. Dalton and Brian W. Duncan 69 Mechanical Support of the Cardiovascular System: Intraaortic Balloon Pumping in Children . 777 L. LuAnn Minich and John A. Hawkins 70 Arrhythmias . 785 Timothy K. Knilans 71 Inflammatory Diseases of the Heart and Pericardium: Infective Endocarditis and Kawasaki Disease . 798 Michael H. Gewitz and Gary M. Satou 72 Inflammatory Diseases of the Heart and Pericardium: Dilated Cardiomyopathy and Myocarditis . 808 Henry B. Wiles, Neil W. Kooy, and Derek S. Wheeler 73 Diseases of the Pericardium . 821 Michael H. Gewitz, Gary M. Satou, and Derek S. Wheeler 74 Management of Hypertension in the Pediatrie Intensive Care Unit . 828 Marianne N. Majdalani and Neil W. Kooy 75 Heart Transplantation . 841 Shamel Abd-Allah and Paul A. Checchia Section VI The Central Nervous System in Critical Illness and Injury 76 Central Nervous System Monitoring . 865 Michael J. Bell and Taeun Chang 77 Molecular Biology of Brain Injury . 872 Michael J. Whalen, Phoebe Yager, EngH. Lo, Josephine Lok, and Natan Noviski 78 Pediatrie Intensive Care Unit Management of Neurosurgical Diseases . 884 Darlene A. Lobel, Mark R. Lee, and Ann-Christine Duhaime 79 Tumors of the Central Nervous System . 894 Robert Tamburro, Raymond С Barfield, and Amar Gajjar Contents xv 80 Intracranial Hypertension. 902 Steven G. Kérnie and Samuel M. Lehman 81 Nonaccidental Trauma and Shaken Baby Syndrome . 916 Robert С Tasker 82 Evaluation of Coma . 924 David J. Michelson and Stephen Ashwal 83 Hypoxie Ischemic Encephalopathy After Cardiorespiratory Arrest . 935 Dermot R. Doherty and fames S. Hutchison 84 Toxic and Metabolic Encephalopathies . 947 Ashok P. Sarnaik and Kathleen L. Meert 85 Infections of the Central Nervous System . 956 Simon Nadel 86 Status Epilepticus . 977 Richard P.M. Chin and Rod С Scott 87 Diseases of the Peripheral Nervous System . 990 Cecil D. Hahn and Brenda L. Banwell Section VII The Gastrointestinal Tract in Critical Illness and Injury 88 Gastrointestinal Bleeding . 1013 Renuka Mehta and Thomas P. Shanley 89 Acute Pancreatitis . 1022 Raffaele Pezzali, Paola Tomassetti, Rosa Ceciliato, and Roberto Corinaldesi 90 Liver Failure in Infants and Children . 1027 Ann Б. Thompson 91 Pediatrie Liver Transplantation . 1040 Gregory M. Tiao and Frederick C. Ryckman 92 Perioperative Management of the Pediatrie Surgical Patient . 1054 David E. Carney, Frederick J. Rescorla, and Jay L. Grosfeld 93 Abdominal Compartment Syndrome in Children . 1073 Gad Bar-Joseph and Raphael Beck 94 Nutritional Support of the Critically 111 Child . 1079 Michael S.D. Agus and Tom Jaksic 95 Nutritional Assessment of the Critically 111 Child . 1090 George Briassoulis Section VIII The Endocrine System in Critical Illness and Injury 96 Inborn Errors of Metabolism . 1103 Nancy Doan Leslie 97 Endocrine Emergencies . 1111 Michael Bigham, Jennifer Kaplan, Neil W. Kooy, and Derek S. Wheeler 98 Endocrine Disorders in the Pediatrie Intensive Care Unit . 1125 Ruth Armano and Greet Van den Berghe Section IX Fluids and Electrolytes in Critical Illness and Injury 99 Renal Physiology . 1143 Russell W. Chesney and Noel M. de los Santos 100 Electrolyte Disorders in the Pediatrie Intensive Care Unit . 1156 Gabriel J. Hauser and Aaron F. Kulick Contents 101 Acid-Base Disorders in the Pediatrie Intensive Care Unit . 1176 James D. Fortenberry, Kiran Hebbar, and Derek S. Wheeler 102 Renal Diseases in the Pediatrie Intensive Care Unit: Thrombotic Microangiopathy, Hemolytic Uremie Syndrome, and Thrombotic Thrombocytopenic Purpura . 1189 François Proulx and Vernon L. Tesh 103 Renal Disorders in the Pediatrie Intensive Care Unit: Glomerulonephritis and Nephrotic Syndrome . 1204 Jen-Jar Lin and William E. Smoyer 104 Acute Renal Failure . 1221 Mai T. Nguyen and John J. Bissler 105 Continuous Renal Replacement Therapy . 1228 Kevin D. McBryde and Timothy E. Bunchman 106 Alternative Indications for Hemofiltration . 1243 Joseph V. DiCarlo and Steven R. Alexander 107 Renal Transplantation . 1250 Coral D. Hanevold, James J. Wynn, and Luis A. Ortiz Section X Hematologic/Oncologic Problems in Critical Illness and Injury 108 Transfusion Medicine . 1263 Jacques Lacroix, Marisa Tucci, France Gauvin, Baruch Toledano, and Heather Hume 109 Disorders of Blood Elements . 1281 Niranjan Kissoon 110 Coagulation, Anticoagulation, and Hemorrhage in the Intensive Care Setting . 1296 Geoffrey M. Fleming, Monika Gupta, and Gail M. Annich 111 Catheter-Related Occlusion and Thrombosis . 1313 Rânjit S. Chima and Brian R. Jacobs 111 Venous Tnromboembolic Disease and Pulmonary Embolism in Children . 1322 N. William Partila and Brian R. Jacobs 113 Care of the Oncology Patient in the Pediatrie Intensive Care Unit . 1332 Robert Tamburro, Raymond C. Barfield, Monika L. Metzger, Terrence L. Geiger, Sandy Call, and Kenneth W. Gow 114 Complications Requiring Critical Care Following Hematopoietic Stem Cell Transplantation . 1355 Kenneth R. Cooke, Paul Richardson, and Gregory A. Yanik Section XI The Immune System in Critical Illness and Injury 115 Pharmacology of Imrmmosuppression . 1379 John F. Sommerauer 116 Primary and Secondary Immunodeficiencies . 1405 Rajesh Aneja and Alexandre T. Rotta 117 Sepsis . 1421 Jan A. Hazelzet, Gertjan J.A. Driessen, Patricia Abboud, Derek S. Wheeler, Thomas P. Shanley, and Hector R. Wong 118 Multiple Organ Dysfunction Syndrome . 1445 Katri Typpo and Michele Mariscalco 119 The Patient with the Human Immunodeficiency Virus in the Pediatrie Intensive Care Unit . I457 Amisha Malhotra, Steven Choi, and Daniel A. Notterman Contents xvii 120 Nosocomial Infections in the Pediatrie Intensive Care Unit . 1472 Mark E. Rowin, Amit Vohra, and John С. Chrisłenson 121 Anaphylaxis . 1486 Todd A. Levin, Cristina M. Mazzoni, and Dennis R. Ownby 122 Rheumatologic Disorders in the Pediatrie Intensive Care Unit . 1492 Steven W. Martin and Michael R. Anderson 123 Infectious Disease-Associated Syndromes . 1511 Isaac Lazar and Clifford W. Bogue Section XII Trauma 124 Trauma Systems and Regionalization of Trauma Care . 1523 Dennis R. Durbin and Michael L. Nance 125 Head and Neck Trauma . 1527 Lisa Grimaldi, Charles L. Schleien, Derek A. Bruce, Amanda Yaun, and Derek S. Wheeler 126 Dental Trauma . 1545 William A. Greenhill and Murray Dock 127 Maxillofacial Trauma . 1551 Likith V. Ready and Haithem Elhadi 128 Eye Trauma and Emergencies . 1558 Stephanie L . Goei, Heojeng Ooi, and Julian J. Nussbaum 129 Thoracic Trauma. 1565 Mindy В. Statter and Donald C. Liu 130 Abdominal Trauma. 1572 Rebeccah L. Brown 131 Genitourinary Trauma . 1579 jR. Guy Hudson and George W. Kaplan 132 Orthopedic Trauma. 1589 Charles T. Mehlman and Alvin ff. Crawford 133 Pediatrie Burns . 1597 Grace Z. Mak, Steven R. Allen, and Richard J. Kagan Section XIII Pharmacology and Toxicology in the Pediatrie Intensive Care Unit 134 Introduction to Pharmacology . 1609 James A. Besunder and John Pope 135 Toxic Exposures: Diagnosis and Management . 1621 Karen S. Powers, Jill M. Cholette, and Patricia Abboud 136 Sedation and Analgesia . 1642 Joseph D. Tobias 137 Procedural Sedation and Anesthesia . 1668 Stephen D. Playfor and Neil S. Morton 138 Neuromuscular Blockade . 1674 Nicholas B. Slamon, Mary С Theroux, and Andrew T. Cestarino, Jr. Section XIV Environmental Emergencies 139 Envenomations . 1687 James Tibballs, Christopher P. Holstege, and Derek S. Wheeler 140 Drowning and Near-Drowning . 1706 Laura M. Ibsen xviii Contents 141 Heat Illness and Hypothermia . 1714 Lynne W. Coule and William Wiers 142 Malignant Hyperthermia . 1725 Richard E. Berlin and Paul]. Samuels 143 Principles of Mass Casualty and Disaster Medicine . 1730 David Markenson, Gad Bar-Joseph, Michael Halberthal, and Derek S. Wheeler 144 An Overview of Chemical and Biologic Agents of Terrorism . 1743 Richard B. Schwartz, Phillip L. Coule, and David Markenson Index . 1765
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spellingShingle	Pediatric critical care medicine basic science and clinical evidence Child Critical Care Critical Illness therapy Infant Pediatric emergencies Pediatric intensive care Pediatrics Kind (DE-588)4030550-8 gnd Intensivmedizin (DE-588)4027263-1 gnd
subject_GND	(DE-588)4030550-8 (DE-588)4027263-1
title	Pediatric critical care medicine basic science and clinical evidence
title_auth	Pediatric critical care medicine basic science and clinical evidence
title_exact_search	Pediatric critical care medicine basic science and clinical evidence
title_exact_search_txtP	Pediatric critical care medicine basic science and clinical evidence
title_full	Pediatric critical care medicine basic science and clinical evidence Derek S. Wheeler ... (ed.)
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title_full_unstemmed	Pediatric critical care medicine basic science and clinical evidence Derek S. Wheeler ... (ed.)
title_short	Pediatric critical care medicine
title_sort	pediatric critical care medicine basic science and clinical evidence
title_sub	basic science and clinical evidence
topic	Child Critical Care Critical Illness therapy Infant Pediatric emergencies Pediatric intensive care Pediatrics Kind (DE-588)4030550-8 gnd Intensivmedizin (DE-588)4027263-1 gnd
topic_facet	Child Critical Care Critical Illness therapy Infant Pediatric emergencies Pediatric intensive care Pediatrics Kind Intensivmedizin
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