Antisense therapeutics:
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
Totowa, NJ
Humana Press
2005
|
| Ausgabe: | 2. ed. |
| Schriftenreihe: | Methods in molecular medicine
106 |
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis Klappentext |
| Beschreibung: | XII, 327 S. Ill., graph. Darst. |
| ISBN: | 1588292053 9781588292056 |
Internformat
MARC
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| 300 | |a XII, 327 S. |b Ill., graph. Darst. | ||
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Datensatz im Suchindex
| _version_ | 1804136634731462656 |
|---|---|
| adam_text | Contents
Foreword
Preface
Contributors
Part I. Introduction
1
M. Ian Phillips
2
Y. Clare Zhang, Meghan M. Taylor, Willis K. Samson,
and M. Ian Phillips
Part II. Cardiovascular
3
Patrick L.
and Martin B. Leon
4
Targeting the Renin-Angiotensin System
M. Ian Phillips and
5
Sian E. Harding,
Part III. Cancer
6
Rosanne M.
7
Preclinical and Clinical Experiences
Ingo
8
of Pancreatic Cancer
Eric Wickstrom,
Atis Chakrabarti, Mohan R. Aruva, Ponugoti S. Rao,
Wenyi Qin, Weizhu Zhu, Edward
and Mathew L. Thakur..
ix
x
9
by Antisense
Kazunori Aoki, Shumpel Ohnami, and Teruhiko Yoshida
10
by Antisense Strategies
Manuel
11
Oligonucleotides in Reversing Drug Resistance
Tadao Funato
Part IV. Blood-Brain Barrier
12
Laura B. Jaeger and William A. Banks
Part V. Dermal
13 Transdermal
Rhonda M. Brand and Patrick L. Iversen
Part VI. Drugs
14
Using Paclitaxel as a Model
Vikram Arora
Part
15
of Inflammatory Bowel Diseases
Bruce R. Yacyshyn
Part
16
of Morpholino Antisense Oligonucleotides Directed Against the
Hepatitis
Ronald Jubin
Index
From Reviews of the First Edition...
...strongly recommended both to scientists already engaged in antisense research and to
newcomers alike. . —Trends in Biotcchnolocy
...
uniquely selective therapeutic agents via precisely designed inhibitors of the expression of disease
associated genes. —Journal of Medicinal Chemistry
Announcement of the complete sequencing of the human genome in April
presence of thousands of targets for antisense oligonucleotides and opened the way to hundreds
of predinical animal studies and some
Therapeutics, a team of leading researchers and clinical scientists demonstrate the new reality of
antisense and
oligonucleotides are being designed and studied in relation to hypertension, various cancers,
inflammatory bowel disease, brain disorders, the blood-brain barrier, and drug delivery. Highlights
include RNA-based therapies for many diseases, up-to-date methods and applications, and insight
into the enormous potential to provide a new generation of drugs.
Highly practical and disease oriented, Antisense Therapeutics, Second Edition offers not only a
primer for a new generation of drug discovery researchers, but also an illuminating exploration of
the potential in exploiting
Features
Accessible introduction to a new
generation of drug discovery
and therapeutics oligonucleotides can be designed and
Up-to-date practical methods and studied to treat disease
applications
|
| adam_txt |
Contents
Foreword
Preface
Contributors
Part I. Introduction
1
M. Ian Phillips
2
Y. Clare Zhang, Meghan M. Taylor, Willis K. Samson,
and M. Ian Phillips
Part II. Cardiovascular
3
Patrick L.
and Martin B. Leon
4
Targeting the Renin-Angiotensin System
M. Ian Phillips and
5
Sian E. Harding,
Part III. Cancer
6
Rosanne M.
7
Preclinical and Clinical Experiences
Ingo
8
of Pancreatic Cancer
Eric Wickstrom,
Atis Chakrabarti, Mohan R. Aruva, Ponugoti S. Rao,
Wenyi Qin, Weizhu Zhu, Edward
and Mathew L. Thakur.
ix
x
9
by Antisense
Kazunori Aoki, Shumpel Ohnami, and Teruhiko Yoshida
10
by Antisense Strategies
Manuel
11
Oligonucleotides in Reversing Drug Resistance
Tadao Funato
Part IV. Blood-Brain Barrier
12
Laura B. Jaeger and William A. Banks
Part V. Dermal
13 Transdermal
Rhonda M. Brand and Patrick L. Iversen
Part VI. Drugs
14
Using Paclitaxel as a Model
Vikram Arora
Part
15
of Inflammatory Bowel Diseases
Bruce R. Yacyshyn
Part
16
of Morpholino Antisense Oligonucleotides Directed Against the
Hepatitis
Ronald Jubin
Index
From Reviews of the First Edition.
".strongly recommended both to scientists already engaged in antisense research and to
newcomers alike.". —Trends in Biotcchnolocy
".
uniquely selective therapeutic agents via precisely designed inhibitors of the expression of disease
associated genes." —Journal of Medicinal Chemistry
Announcement of the complete sequencing of the human genome in April
presence of thousands of targets for antisense oligonucleotides and opened the way to hundreds
of predinical animal studies and some
Therapeutics, a team of leading researchers and clinical scientists demonstrate the new reality of
antisense and
oligonucleotides are being designed and studied in relation to hypertension, various cancers,
inflammatory bowel disease, brain disorders, the blood-brain barrier, and drug delivery. Highlights
include RNA-based therapies for many diseases, up-to-date methods and applications, and insight
into the enormous potential to provide a new generation of drugs.
Highly practical and disease oriented, Antisense Therapeutics, Second Edition offers not only a
primer for a new generation of drug discovery researchers, but also an illuminating exploration of
the potential in exploiting
Features
Accessible introduction to a new
generation of drug discovery
and therapeutics oligonucleotides can be designed and
Up-to-date practical methods and studied to treat disease
applications |
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| illustrated | Illustrated |
| index_date | 2024-07-02T18:05:06Z |
| indexdate | 2024-07-09T20:59:31Z |
| institution | BVB |
| isbn | 1588292053 9781588292056 |
| language | English |
| lccn | 2004006680 |
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| physical | XII, 327 S. Ill., graph. Darst. |
| publishDate | 2005 |
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| publisher | Humana Press |
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| series | Methods in molecular medicine |
| series2 | Methods in molecular medicine |
| spelling | Antisense therapeutics ed. by M. Ian Phillips ... 2. ed. Totowa, NJ Humana Press 2005 XII, 327 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Methods in molecular medicine 106 Acides nucléiques antisens - Emploi en thérapeutique aAntisense nucleic acids xTherapeutic use aOligonucleotides, Antisense xtherapeutic use aOligonucleotides, Antisense xpharmacology Antisense-Nucleinsäuren (DE-588)4282992-6 gnd rswk-swf Molekulare Medizin (DE-588)4543844-4 gnd rswk-swf Antisense-Nucleinsäuren (DE-588)4282992-6 s Molekulare Medizin (DE-588)4543844-4 s b DE-604 Phillips, M. Ian Sonstige oth Methods in molecular medicine 106 (DE-604)BV011334960 106 Digitalisierung UB Regensburg application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=015733312&sequence=000003&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis Digitalisierung UB Regensburg application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=015733312&sequence=000004&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA Klappentext |
| spellingShingle | Antisense therapeutics Methods in molecular medicine Acides nucléiques antisens - Emploi en thérapeutique aAntisense nucleic acids xTherapeutic use aOligonucleotides, Antisense xtherapeutic use aOligonucleotides, Antisense xpharmacology Antisense-Nucleinsäuren (DE-588)4282992-6 gnd Molekulare Medizin (DE-588)4543844-4 gnd |
| subject_GND | (DE-588)4282992-6 (DE-588)4543844-4 |
| title | Antisense therapeutics |
| title_auth | Antisense therapeutics |
| title_exact_search | Antisense therapeutics |
| title_exact_search_txtP | Antisense therapeutics |
| title_full | Antisense therapeutics ed. by M. Ian Phillips ... |
| title_fullStr | Antisense therapeutics ed. by M. Ian Phillips ... |
| title_full_unstemmed | Antisense therapeutics ed. by M. Ian Phillips ... |
| title_short | Antisense therapeutics |
| title_sort | antisense therapeutics |
| topic | Acides nucléiques antisens - Emploi en thérapeutique aAntisense nucleic acids xTherapeutic use aOligonucleotides, Antisense xtherapeutic use aOligonucleotides, Antisense xpharmacology Antisense-Nucleinsäuren (DE-588)4282992-6 gnd Molekulare Medizin (DE-588)4543844-4 gnd |
| topic_facet | Acides nucléiques antisens - Emploi en thérapeutique aAntisense nucleic acids xTherapeutic use aOligonucleotides, Antisense xtherapeutic use aOligonucleotides, Antisense xpharmacology Antisense-Nucleinsäuren Molekulare Medizin |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=015733312&sequence=000003&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=015733312&sequence=000004&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA |
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