Handbook of assay development in drug discovery:
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
Boca Raton
CRC/Taylor & Francis
2006
|
| Schriftenreihe: | Drug discovery series
5 |
| Schlagworte: | |
| Online-Zugang: | Publisher description Inhaltsverzeichnis |
| Beschreibung: | Includes bibliographical references and index |
| Beschreibung: | 464 S. Ill., graph. Darst. 27 cm |
| ISBN: | 1574444719 9781574444711 |
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| 490 | 1 | |a Drug discovery series |v 5 | |
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| 650 | 4 | |a Médicaments - Conception - Guides, manuels, etc | |
| 650 | 4 | |a Médicaments - Développement - Guides, manuels, etc | |
| 650 | 4 | |a Médicaments - Recherche - Guides, manuels, etc | |
| 650 | 4 | |a Drug development |v Handbooks, manuals, etc | |
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| 650 | 4 | |a Drugs |x Design |v Handbooks, manuals, etc | |
| 650 | 4 | |a Drug Delivery Systems |x methods |v Laboratory Manuals | |
| 650 | 4 | |a Pharmaceutical Preparations |x analysis |v Laboratory Manuals | |
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| adam_text | U DRUG DISCOVERY SERIES/5 HANDBOOK OF ASSAY DEVELOPMENT IN DRUG
DISCOVERY EDITED BY LISA K. MINOR TAYLOR & FRANCIS TAYLOR & FRANCIS
GROUP BOCA RATON LONDON NEW YORK A CRC TITLE, PART OF THE TAYLOR &
FRANCIS IMPRINT, A MEMBER OF THE TAYLOR & FRANCIS CROUP, THE ACADEMIC
DIVISION OF TSCF INFORMA PIC. TABLE OF CONTENTS CHAPTER 1 PROTEIN
KINASES IN DRUG DISCOVERY: RATIONALE, SUCCESS, AND CHALLENGE 1 DANA L.
JOHNSON AND JAN L. SECHLER CHAPTER 2 AN INTRODUCTION TO THE PROTEIN
TYROSINE PHOSPHATASE GENE FAMILY AND SCREENING ASSAY DEVELOPMENT 7
DOMINIQUE PERRIN AND ROB HOOFT VAN HUIJSDUIJNEN CHAPTER 3 TIME-RESOLVED
FLUORESCENCE BASED ASSAYS FOR KINASES 25 ZHUYIN LI AND TINA GARYANTES
CHAPTER 4 DEVELOPMENT OF HIGH-THROUGHPUT SCREENING ASSAYS IN
SCINTILLATING MICROPLATES (FLASHPLATES) TO IDENTIFY INHIBITORS OF KINASE
ACTIVITY 39 STUART EMANUEL CHAPTER 5 DEVELOPMENT OF HIGH-THROUGHPUT
SCREENING ASSAYS FOR KINASE DRUG TARGETS USING ALPHASCREEN* TECHNOLOGY
53 DEAN WENHAM, CHANTAL ILLY, JACQUES ANDRE ST. PIERRE, AND NATHALIE
BOUCHARD CHAPTER 6 HOMOGENEOUS HIGH-THROUGHPUT SCREENING (HTS) ASSAYS
FOR SERINE/THREONINE KINASES USING P-GALACTOSIDASE ENZYME FRAGMENT
COMPLEMENTATION 71 INNA VAINSHTEIN, TABASSUM NAQVI, ANICE HIM, RIAZ
ROUHANI, LINDY KAUFFMAN, RAJENDRA SINGH, AND RICHARD M. EGLEN CHAPTER 7
IMAP ASSAYS FOR PROTEIN KINASES 85 RICHARD SPORTSMAN CHAPTER 8 A
HOMOGENEOUS, LUMINESCENT, HIGH-THROUGHPUT, VERSATILE ASSAY FOR A WIDE
RANGE OF KINASES 97 SAID A. GOUELI, KEVIN HSIAO, AND BOB BULLEIT CHAPTER
9 PROTEASES AS DRUG TARGETS 113 ROBIN L. THURMOND AND JAMES P. EDWARDS
CHAPTER 10 A COMPARISON OF HOMOGENEOUS BIOLUMINESCENT AND FLUORESCENT
METHODS FOR PROTEASE ASSAYS 25 MARTHA A. O BRIEN CHAPTER 11
SCINTILLATION PROXIMITY ASSAY (SPA) RECEPTOR BINDING ASSAYS 141 JEFFREY
R. COOK, ROBERT GRAVES, MOLLY J. PRICE-JONES, JENNY A. BERRY, AND KELVIN
T. HUGHES CHAPTER 12 RADIOLIGAND BINDING FILTRATION ASSAY: FULL
AUTOMATION 159 STEPHEN K.-F. WONG CHAPTER 13 NUCLEAR RECEPTORS AS DRUG
TARGETS 173 PATRICIA D. PELTON CHAPTER 14 NUCLEAR RECEPTOR SCINTILLATION
PROXIMITY ASSAYS 183 DAVID POWELL AND MOLLY J. PRICE-JONES CHAPTER 15
HOMOGENEOUS ASSAY DEVELOPMENT FOR NUCLEAR RECEPTOR USING ALPHASCREEN*
TECHNOLOGY 193 NATHALIE ROULEAU AND ROGER BOSSE CHAPTER 16 DEVELOPMENT
OF NUCLEAR RECEPTOR HOMOGENEOUS ASSAY USING THE LANCE* TECHNOLOGY 209
NATHALIE ROULEAU, PERTTI HURSKAINEN, ROGER BOSSE, AND LLKKA HEMMILD
CHAPTER 17 THE EMERGING ROLE OF CELL-BASED ASSAYS IN DRUG DISCOVERY 221
RALPH J. GARIPPA CHAPTER 18 THE PREPARATION OF CELLS FOR HIGH-CONTENT
SCREENING 227 ANN F. HOFFMAN CHAPTER 19 THE EVOLUTION OF CAMP ASSAYS 243
PATRICIA KASILA AND HARRY HARNEY CHAPTER 20 A HOMOGENEOUS, FLUORESCENT
POLARIZATION ASSAY FOR INOSITOL 1,4,5-TRISPHOSPHATE (INS P 3 ) 269 PETER
FUNG, RAJENDRA SINGH, LINDY KAUFFMAN, RICHARD M. EGLEN, AND TABASSUM
NAQVI CHAPTER 21 SCINTILLATION PROXIMITY ASSAY OF INOSITOL PHOSPHATES
285 WEI ZHENG AND PHILIP E. BRANDISH CHAPTER 22 MEASURING CALCIUM
MOBILIZATION WITH GQ-COUPLED GPCRS USING THE FLUOROMETRIC IMAGING PLATE
READER (FLIPR) 293 JOHN DUNLOP, YINGXIN ZHANG, ROBERT RING, AND DIANNE
KOWAL CHAPTER 23 DEVELOPMENT OF FLIPR-BASED HTS ASSAY FOR G R COUPLED
GPCRS 305 CAILIN CHEN, CHARLES SMITH, LISA MINOR, AND BRUCE DAMIANO
CHAPTER 24 AURORA ASSAYS 319 PRIYA KUNAPULI CHAPTER 25 MEMBRANE
POTENTIAL BASED ASSAYS FOR ION CHANNELS AND ELECTROGENIC TRANSPORTERS
343 QIANG LII, STEPHEN LIN, AND JOHN DUNLOP CHAPTER 26 REPORTER GENE
ASSAYS FOR DRUG DISCOVERY 357 KEITH A. HOUCK, WAYNE P. BOCCHINFUSO,
MICHELE S. DOWLESS, AND KRISTEN M. BORCHERT CHAPTER 27 MRNA DETECTION
FROM CELLS USING QUANTIGENE BRANCHED DNA TECHNOLOGY 371 LISA MINOR
CHAPTER 28 HOMOGENEOUS MULTIWELL ASSAYS FOR MEASURING CELL VIABILITY,
CYTOTOXICITY, AND APOPTOSIS 385 TERRY L. RISS, RICHARD A. MORAVEC,
MARTHA A. O BRIEN, ERIKA M. HAWKINS, AND ANDREW NILES CHAPTER 29
DEVELOPMENT OF IMAGE-BASED ASSAYS FOR DRUG DISCOVERY 407 SUSAN M.
CATALANO CHAPTER 30 GPCR INTERNALIZATION MEASURED BY IMAGE ANALYSIS 419
ROBERT GRAVES, MICHAEL J. FRANCIS, LYNNE SMITH, JEFFREY R. COOK, AND
ELAINE J. ADIE CHAPTER 31 TRANSFLUOR PROVIDES A UNIVERSAL CELL-BASED
ASSAY FOR SCREENING G PROTEIN-COUPLED RECEPTORS 431 ROBERT H. OAKLEY,
CONRAD L. COWAN, CHRISTINE C. HUDSON, AND CARSON R. LOOMIS INDEX 455
|
| adam_txt |
U DRUG DISCOVERY SERIES/5 HANDBOOK OF ASSAY DEVELOPMENT IN DRUG
DISCOVERY EDITED BY LISA K. MINOR TAYLOR & FRANCIS TAYLOR & FRANCIS
GROUP BOCA RATON LONDON NEW YORK A CRC TITLE, PART OF THE TAYLOR &
FRANCIS IMPRINT, A MEMBER OF THE TAYLOR & FRANCIS CROUP, THE ACADEMIC
DIVISION OF TSCF INFORMA PIC. TABLE OF CONTENTS CHAPTER 1 PROTEIN
KINASES IN DRUG DISCOVERY: RATIONALE, SUCCESS, AND CHALLENGE 1 DANA L.
JOHNSON AND JAN L. SECHLER CHAPTER 2 AN INTRODUCTION TO THE PROTEIN
TYROSINE PHOSPHATASE GENE FAMILY AND SCREENING ASSAY DEVELOPMENT 7
DOMINIQUE PERRIN AND ROB HOOFT VAN HUIJSDUIJNEN CHAPTER 3 TIME-RESOLVED
FLUORESCENCE BASED ASSAYS FOR KINASES 25 ZHUYIN LI AND TINA GARYANTES
CHAPTER 4 DEVELOPMENT OF HIGH-THROUGHPUT SCREENING ASSAYS IN
SCINTILLATING MICROPLATES (FLASHPLATES) TO IDENTIFY INHIBITORS OF KINASE
ACTIVITY 39 STUART EMANUEL CHAPTER 5 DEVELOPMENT OF HIGH-THROUGHPUT
SCREENING ASSAYS FOR KINASE DRUG TARGETS USING ALPHASCREEN* TECHNOLOGY
53 DEAN WENHAM, CHANTAL ILLY, JACQUES ANDRE ST. PIERRE, AND NATHALIE
BOUCHARD CHAPTER 6 HOMOGENEOUS HIGH-THROUGHPUT SCREENING (HTS) ASSAYS
FOR SERINE/THREONINE KINASES USING P-GALACTOSIDASE ENZYME FRAGMENT
COMPLEMENTATION 71 INNA VAINSHTEIN, TABASSUM NAQVI, ANICE HIM, RIAZ
ROUHANI, LINDY KAUFFMAN, RAJENDRA SINGH, AND RICHARD M. EGLEN CHAPTER 7
IMAP ASSAYS FOR PROTEIN KINASES 85 RICHARD SPORTSMAN CHAPTER 8 A
HOMOGENEOUS, LUMINESCENT, HIGH-THROUGHPUT, VERSATILE ASSAY FOR A WIDE
RANGE OF KINASES 97 SAID A. GOUELI, KEVIN HSIAO, AND BOB BULLEIT CHAPTER
9 PROTEASES AS DRUG TARGETS 113 ROBIN L. THURMOND AND JAMES P. EDWARDS
CHAPTER 10 A COMPARISON OF HOMOGENEOUS BIOLUMINESCENT AND FLUORESCENT
METHODS FOR PROTEASE ASSAYS '25 MARTHA A. O'BRIEN CHAPTER 11
SCINTILLATION PROXIMITY ASSAY (SPA) RECEPTOR BINDING ASSAYS 141 JEFFREY
R. COOK, ROBERT GRAVES, MOLLY J. PRICE-JONES, JENNY A. BERRY, AND KELVIN
T. HUGHES CHAPTER 12 RADIOLIGAND BINDING FILTRATION ASSAY: FULL
AUTOMATION 159 STEPHEN K.-F. WONG CHAPTER 13 NUCLEAR RECEPTORS AS DRUG
TARGETS 173 PATRICIA D. PELTON CHAPTER 14 NUCLEAR RECEPTOR SCINTILLATION
PROXIMITY ASSAYS 183 DAVID POWELL AND MOLLY J. PRICE-JONES CHAPTER 15
HOMOGENEOUS ASSAY DEVELOPMENT FOR NUCLEAR RECEPTOR USING ALPHASCREEN*
TECHNOLOGY 193 NATHALIE ROULEAU AND ROGER BOSSE CHAPTER 16 DEVELOPMENT
OF NUCLEAR RECEPTOR HOMOGENEOUS ASSAY USING THE LANCE* TECHNOLOGY 209
NATHALIE ROULEAU, PERTTI HURSKAINEN, ROGER BOSSE, AND LLKKA HEMMILD
CHAPTER 17 THE EMERGING ROLE OF CELL-BASED ASSAYS IN DRUG DISCOVERY 221
RALPH J. GARIPPA CHAPTER 18 THE PREPARATION OF CELLS FOR HIGH-CONTENT
SCREENING 227 ANN F. HOFFMAN CHAPTER 19 THE EVOLUTION OF CAMP ASSAYS 243
PATRICIA KASILA AND HARRY HARNEY CHAPTER 20 A HOMOGENEOUS, FLUORESCENT
POLARIZATION ASSAY FOR INOSITOL 1,4,5-TRISPHOSPHATE (INS P 3 ) 269 PETER
FUNG, RAJENDRA SINGH, LINDY KAUFFMAN, RICHARD M. EGLEN, AND TABASSUM
NAQVI CHAPTER 21 SCINTILLATION PROXIMITY ASSAY OF INOSITOL PHOSPHATES
285 WEI ZHENG AND PHILIP E. BRANDISH CHAPTER 22 MEASURING CALCIUM
MOBILIZATION WITH GQ-COUPLED GPCRS USING THE FLUOROMETRIC IMAGING PLATE
READER (FLIPR) 293 JOHN DUNLOP, YINGXIN ZHANG, ROBERT RING, AND DIANNE
KOWAL CHAPTER 23 DEVELOPMENT OF FLIPR-BASED HTS ASSAY FOR G R COUPLED
GPCRS 305 CAILIN CHEN, CHARLES SMITH, LISA MINOR, AND BRUCE DAMIANO
CHAPTER 24 AURORA ASSAYS 319 PRIYA KUNAPULI CHAPTER 25 MEMBRANE
POTENTIAL BASED ASSAYS FOR ION CHANNELS AND ELECTROGENIC TRANSPORTERS
343 QIANG LII, STEPHEN LIN, AND JOHN DUNLOP CHAPTER 26 REPORTER GENE
ASSAYS FOR DRUG DISCOVERY 357 KEITH A. HOUCK, WAYNE P. BOCCHINFUSO,
MICHELE S. DOWLESS, AND KRISTEN M. BORCHERT CHAPTER 27 MRNA DETECTION
FROM CELLS USING QUANTIGENE BRANCHED DNA TECHNOLOGY 371 LISA MINOR
CHAPTER 28 HOMOGENEOUS MULTIWELL ASSAYS FOR MEASURING CELL VIABILITY,
CYTOTOXICITY, AND APOPTOSIS 385 TERRY L. RISS, RICHARD A. MORAVEC,
MARTHA A. O'BRIEN, ERIKA M. HAWKINS, AND ANDREW NILES CHAPTER 29
DEVELOPMENT OF IMAGE-BASED ASSAYS FOR DRUG DISCOVERY 407 SUSAN M.
CATALANO CHAPTER 30 GPCR INTERNALIZATION MEASURED BY IMAGE ANALYSIS 419
ROBERT GRAVES, MICHAEL J. FRANCIS, LYNNE SMITH, JEFFREY R. COOK, AND
ELAINE J. ADIE CHAPTER 31 TRANSFLUOR PROVIDES A UNIVERSAL CELL-BASED
ASSAY FOR SCREENING G PROTEIN-COUPLED RECEPTORS 431 ROBERT H. OAKLEY,
CONRAD L. COWAN, CHRISTINE C. HUDSON, AND CARSON R. LOOMIS INDEX 455 |
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| illustrated | Illustrated |
| index_date | 2024-07-02T18:02:43Z |
| indexdate | 2024-07-09T20:59:22Z |
| institution | BVB |
| isbn | 1574444719 9781574444711 |
| language | English |
| lccn | 2005053104 |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-015726155 |
| oclc_num | 61456738 |
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| owner_facet | DE-19 DE-BY-UBM |
| physical | 464 S. Ill., graph. Darst. 27 cm |
| publishDate | 2006 |
| publishDateSearch | 2006 |
| publishDateSort | 2006 |
| publisher | CRC/Taylor & Francis |
| record_format | marc |
| series | Drug discovery series |
| series2 | Drug discovery series |
| spelling | Handbook of assay development in drug discovery edited by Lisa K. Minor Boca Raton CRC/Taylor & Francis 2006 464 S. Ill., graph. Darst. 27 cm txt rdacontent n rdamedia nc rdacarrier Drug discovery series 5 Includes bibliographical references and index Médicaments - Conception - Guides, manuels, etc Médicaments - Développement - Guides, manuels, etc Médicaments - Recherche - Guides, manuels, etc Drug development Handbooks, manuals, etc Drugs Research Handbooks, manuals, etc Drugs Design Handbooks, manuals, etc Drug Delivery Systems methods Laboratory Manuals Pharmaceutical Preparations analysis Laboratory Manuals Minor, Lisa K. Sonstige oth Drug discovery series 5 (DE-604)BV021489525 5 http://www.loc.gov/catdir/enhancements/fy0648/2005053104-d.html Publisher description GBV Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=015726155&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Handbook of assay development in drug discovery Drug discovery series Médicaments - Conception - Guides, manuels, etc Médicaments - Développement - Guides, manuels, etc Médicaments - Recherche - Guides, manuels, etc Drug development Handbooks, manuals, etc Drugs Research Handbooks, manuals, etc Drugs Design Handbooks, manuals, etc Drug Delivery Systems methods Laboratory Manuals Pharmaceutical Preparations analysis Laboratory Manuals |
| title | Handbook of assay development in drug discovery |
| title_auth | Handbook of assay development in drug discovery |
| title_exact_search | Handbook of assay development in drug discovery |
| title_exact_search_txtP | Handbook of assay development in drug discovery |
| title_full | Handbook of assay development in drug discovery edited by Lisa K. Minor |
| title_fullStr | Handbook of assay development in drug discovery edited by Lisa K. Minor |
| title_full_unstemmed | Handbook of assay development in drug discovery edited by Lisa K. Minor |
| title_short | Handbook of assay development in drug discovery |
| title_sort | handbook of assay development in drug discovery |
| topic | Médicaments - Conception - Guides, manuels, etc Médicaments - Développement - Guides, manuels, etc Médicaments - Recherche - Guides, manuels, etc Drug development Handbooks, manuals, etc Drugs Research Handbooks, manuals, etc Drugs Design Handbooks, manuals, etc Drug Delivery Systems methods Laboratory Manuals Pharmaceutical Preparations analysis Laboratory Manuals |
| topic_facet | Médicaments - Conception - Guides, manuels, etc Médicaments - Développement - Guides, manuels, etc Médicaments - Recherche - Guides, manuels, etc Drug development Handbooks, manuals, etc Drugs Research Handbooks, manuals, etc Drugs Design Handbooks, manuals, etc Drug Delivery Systems methods Laboratory Manuals Pharmaceutical Preparations analysis Laboratory Manuals |
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