Replantation and transplantation:
Gespeichert in:
Format: | Buch |
---|---|
Sprache: | English |
Veröffentlicht: |
Philadelphia [u.a.]
Elsevier Saunders
2007
|
Schriftenreihe: | Clinics in plastic surgery
34,2 |
Schlagworte: | |
Online-Zugang: | Inhaltsverzeichnis |
Beschreibung: | XIV S., S. 167 - 330 zahlr. Ill. |
ISBN: | 9781416042945 1416042946 |
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245 | 1 | 0 | |a Replantation and transplantation |c guest ed. Ramazi O. Datiashvili |
264 | 1 | |a Philadelphia [u.a.] |b Elsevier Saunders |c 2007 | |
300 | |a XIV S., S. 167 - 330 |b zahlr. Ill. | ||
336 | |b txt |2 rdacontent | ||
337 | |b n |2 rdamedia | ||
338 | |b nc |2 rdacarrier | ||
490 | 1 | |a Clinics in plastic surgery |v 34,2 | |
650 | 4 | |a Reimplantation (Surgery) | |
650 | 4 | |a Surgery, Plastic | |
650 | 4 | |a Transplantation of organs, tissues, etc | |
700 | 1 | |a Datiashvili, Ramazi O. |e Sonstige |4 oth | |
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adam_text | REPLANTATION AND TRANSPLANTATION
Contents
2«U^fflKÍÍnmgiÍI!@g^ i* aWPtíít^ ** ktrf (. .*»»»%»», Allí
Ramazi O. Datiashvili
PARTI: REPLANTATION
Sol utiojistQ.Ch.difinfliaa CJ^lteLReBJantatiQns.^ _,._.,„„„„,„,.. 167
Ramazi O. Datiashvili, Kevin R. Knox, and Gordon M. Kaplan
Replantation of amputated digits remains one of the most challenging areas in plastic
and reconstructive surgery. Complicated cases of digital amputation, such as fingertip
amputations, multidigital amputations, and so forth, pose an even greater challenge,
requiring extraordinary solutions for successful replantation. The authors present their
experience with complicated digital replantations at the University of Medicine and
Dentistry of New Jersey New Jersey Medical School. Cases presented include fingertip
replantation, replantation of a finger with impairment of arterial inflow, and two cases
of multidigital amputations. In one case of multidigital amputation, heterodigital
replantation was performed, and in the other case, a minute skin neurovascular free flap
from a nonreplantable finger was used for the reconstruction of another injured finger.
Presented cases demonstrate various tools that can be successfully used in the
performance of challenging digital replantations.
Bradley D. Medling, Reuben A. Bueno, Jr. Robert C. Russell, and Michael W. Neumeister
Replantation aims to restore the amputated part to its anatomical site, preserving
function and appearance. Outcome depends on factors intrinsic to the patient and to the
nature of the injury. Young patients who have distal, cleanly amputated extremities have
the best return of function; multiple levels of injury, crush, or avulsing injuries have less.
Patients must be fully informed about the commitment to rehabilitation and the
possibility of multiple surgeries needed for best results. Similarly, patient and surgeon
expectations should be evaluated and addressed before replantation. Meticulous
microsurgical technique, comprehensive occupational therapy, and perseverance are
needed for success. Addressing these issues promotes a team rehabilitation to restore
function while getting the amputation patient back to productive position in society.
Darrell Brooks, Rudolf F. Buntic, Gabe M. Kind, Karin Schott, Gregory M. Buncke,
and Harry J. Buncke
Ring avulsion injury is classically believed to be one of the most challenging for the
reconstructive surgeon. Injury patterns include a spectrum from laceration to complete
amputation, with differential magnitude of injury to soft tissue, tendon, joint complex,
and bone. Although ring avulsion injury can result in devastating functional and
aesthetic loss to the hand, fear of even greater functional loss has made replantation
a relative contraindication for this complex injury. This article hopes to clarify the
pathomechanics and anatomy of ring avulsion, such that the elements of injury, which
lead to poor survival and poor function, can be adequately addressed in the surgical
plan.
Nonextremity Replantation: The Management of Amputations of the Facial Parts
Roberto L Flores, Alexes Hazen, Robert D. Galiano, Andrew M. Klapper,
and Jamie P. Levine
Successful nonextremity replantations, particularly of the facial anatomy and testicles,
are rare procedures, and only a handful of cases have been reported. This article reviews
the current literature in nonextremity replantations and representative cases performed
at the authors institution. Certain underlying themes and problems are consistently
encountered in the surgical management of these cases. These are identified and
reviewed. Although the replantation of these body parts remains technically
challenging, all efforts should be made, when indicated, to repair these injuries
microsurgically, because it currently offers the best reconstructive solution for these
patients.
Extremity Reconstruction Usjmiit||QnjB«Jajnta^
Robert C. Russell, Michael W. Neumeister, Srdjan Andrei Ostric, and Nitin J. Engineer
After a severe digital or extremity injury, the replantation surgeon should always seek to
make the best use out of what tissue is available for reconstruction. Exercising sound
surgical judgment and being creative allow the surgeon to restore function to critical
areas of the hand or extremity by the judicious use of available tissues that would
otherwise be discarded. The use of spare parts should, therefore, always be considered
to facilitate digital or extremity reconstruction when routine replantation is not possible
or is likely to produce a poor functional result. The surgeon should always try to use
available nonreplantable tissue to preserve length, obtain soft tissue coverage, or most
importantly improve the function of remaining less injured digits. This article presents
several case studies that illustrate the principals of spare parts reconstruction performed
at the time of the initial debridement using nonreplantable tissue to provide coverage or
improve function.
^^ 223l.
Charles K. Lee and Gregory M. Buncke
Great toe to thumb transplantation offers the ideal reconstruction because it replaces the
absent thumb with nearly identical anatomy. Functional donor site morbidity is
minimal as compared with the aesthetic one; however, in comparison to the hand, the
functional and aesthetic gain is tremendous. Anatomic and operative details are
discussed along with preoperative and postoperative management. Postoperative
functional evaluation of the thumb and donor site is assessed. Forty years of experience
with this composite tissue transplantation has proven its status as the gold standard for
thumb reconstruction.
PART II: TRANSPLANTATION
Research and Events Leading to Facial Transplantation 233
John H. Barker, Niki Stamos, Allen Furr, Sean McGuire, Michael Cunningham,
Osborne Wiggins, Charles S. Brown, Brian Gander, Claudio Maldonado,
and Joseph C. Banis, Jr
Facial transplantation has long captured the interest and imagination of scientists, the
media, and the lay public. Facial transplantation could provide an excellent alternative
to current treatments for facial disfigurement caused by burns, trauma, cancer
extirpation, or congenital birth defects. This article discusses the major technical,
immunologie, psychosocial and ethical hurdles that have been overcome to bring facial
transplantation from an idea to a clinical reality by providing the reader with
a chronologic overview of the research and events that have led this exciting new
treatment into the clinical arena.
Maria Siemionow and Galip Agaoglu
The functional and aesthetic outcome following application of conventional
reconstructive procedures or prosthetic materials is not satisfactory, especially in
patients who have severe deformities and disabilities. Since the first successful hand
transplantation in France in 1998, composite tissue allograft transplantation has gained
a great deal of interest in the field of plastic surgery. It is obvious that composite tissue
allograft transplantation will improve patients life quality, but this might be at the
expense of decreasing life expectancy. Currently, the main obstacle for composite tissue
allograft transplantation is the use of life long ¡mmunosuppression therapy because of
their well known side effects. In addition, the ethical, social, and psychologic issues are
raised when discussing face transplantation. The long term results of the recently
performed partial face transplantations will be critical to judge the future applications of
partial or total face transplantation.
Transplantation of the Hand, Face, and Composite Structures: Evolution and Current
Gordon R. Tobin, Warren C. Breidenbach, III, Diane J. Pidwell, Suzanne T. lldstad,
and Kadiyala V. Ravindra
This article reviews the world experience in the newly emerging field of composite tissue
allotransplantation. These allografts contain multiple tissues that are usually muscu
loskeletal structures with a skin or epithelial surface, such as hand, facial structures,
larynx, tongue, ear, knee/femur, abdominal wall, and penis. They represent a new
transplantation field, with only a 10 year experience and just over 50 clinical cases. This
review of the 10 year world experience found uniform technical success, immunologie
biology, and immunosuppression regimens very similar to solid organ transplants, and
success strongly correlated with adherence to guidelines for psychiatric screening,
thorough preparation of patient and families, intense postoperative monitoring, and
assurance of medication access. All failures reported have been caused by lapses in these
parameters. This early experience shows a great potential for application of these new
procedures to the most challenging reconstructive needs.
Bardia Amirlak, Ruben Gonzalez, Vijay Gorantla, Warren C. Breidenbach, III,
and Gordon R. Tobin
Successful hand transplantation depends upon an extensive, well coordinated system
with resources and experience in both upper extremity and transplant surgery. This
description of such a system is drawn from the experience of the Louisville, Kentucky,
Hand Transplant Program, which achieved the world s first successful hand transplant in
January 1999, and which is the only United States program to date. The personnel and
components of this system are outlined, with a detailed description of the roles,
responsibilities, and interaction between components. This system ensures optimal
management throughout recipient selection, psychiatric screening, education and
preparation, donor limb retrieval, transplant surgery, immunosuppression administra¬
tion and monitoring, and post transplant rehabilitation therapy. The lessons learned
from the experience of the Louisville team, and the experiences of the other teams
world wide, are presented to guide organization of future teams participating in this
pioneering endeavor.
Cellular Theraoies for Prolongation of CoiiiDOSite Tissue .Allograft Tfansplantation 291
Justin M. Sacks, Elaine K. Horibe, and W.P. Andrew Lee
Complex musculoskeletal defects resulting from cancer, congenital absence, and trauma
represent a unique reconstructive challenge. Autologous tissue is often unavailable to
reconstruct these deformities. Composite tissue allograft transplantation represents
a unique solution for these clinical problems. Face, hand, or limb transplants can be
performed in a single procedure. However, the use of chronic nonspecific systemic
immunosuppression can lead to side effects such as drug toxicity, opportunistic
infections, and malignancies. This article explores various cell based therapies that
represent promising modalities to reduce chronic immunosuppression and alter the
risk/benefit ratios for the prospect of composite tissue allograft transplantation.
The Immunology of C^njRojjjtjp TMMftJaOiiliOtation 303
Diane J. Pidwell and Carolyn Burns
Composite tissue allotransplantation holds great potential for reconstructive surgery.
That these procedures can be successful has been clearly demonstrated by the success of
hand, face, and larynx transplants around the world. Although the immunology of
composite tissue allotransplantation mirrors that of any allogeneic organ transplant,
there are several unique aspects to these grafts. This article reviews the immunology of
transplantation, histocompatibility testing for composite tissue allotransplantation,
graft rejection, immunosuppression, and specific immunologie considerations of
composite tissue allotransplantation.
Tissue Engineering: Bridging the Gap Between Replantation and Composite Tissue
MlSSBSEL, ¦mrnnr ir T .m.nr r.nr „r „ rnirn n,,.» TTTn.,,,,...»»»«..,, mmM mmmUJMmmumujuí mKj*MmmMm^*jML*m«aí3l
David M. Megee, Nada Berry, Robert C. Russell, and Michael W. Neumeister
This article explores issues related to tissue engineering and composite tissue allografts
that employ physiologic and anatomic autogenous replicates to restore tissue loss.
Composite tissue allotransplantation has become a controversial option for re¬
construction, most prominently for reconstruction involving the hand and, recently,
the face. While the side effect profile of systemic immunosuppression continues to
improve, the long term risks of immunosuppression leaves composite tissue allotrans¬
plantation a domain for cautious exploration. Meanwhile, tissue engineering could,
conceivably, be the gap between replantation and composite tissue allografts. Whereas
the perils of immunosuppression may limit the routine use of allografts, employing
constructions made of the patient s own cells negates the need for any antirejection
therapy.
|
adam_txt |
REPLANTATION AND TRANSPLANTATION
Contents
2«U^fflKÍÍnmgiÍI!@g^ i* aWPtíít^ ** ktrf (. .*»»»%»», Allí
Ramazi O. Datiashvili
PARTI: REPLANTATION
Sol utiojistQ.Ch.difinfliaa CJ^lteLReBJantatiQns.^ _,._.,„„„„,„,. 167
Ramazi O. Datiashvili, Kevin R. Knox, and Gordon M. Kaplan
Replantation of amputated digits remains one of the most challenging areas in plastic
and reconstructive surgery. Complicated cases of digital amputation, such as fingertip
amputations, multidigital amputations, and so forth, pose an even greater challenge,
requiring extraordinary solutions for successful replantation. The authors present their
experience with complicated digital replantations at the University of Medicine and
Dentistry of New Jersey New Jersey Medical School. Cases presented include fingertip
replantation, replantation of a finger with impairment of arterial inflow, and two cases
of multidigital amputations. In one case of multidigital amputation, heterodigital
replantation was performed, and in the other case, a minute skin neurovascular free flap
from a nonreplantable finger was used for the reconstruction of another injured finger.
Presented cases demonstrate various tools that can be successfully used in the
performance of challenging digital replantations.
Bradley D. Medling, Reuben A. Bueno, Jr. Robert C. Russell, and Michael W. Neumeister
Replantation aims to restore the amputated part to its anatomical site, preserving
function and appearance. Outcome depends on factors intrinsic to the patient and to the
nature of the injury. Young patients who have distal, cleanly amputated extremities have
the best return of function; multiple levels of injury, crush, or avulsing injuries have less.
Patients must be fully informed about the commitment to rehabilitation and the
possibility of multiple surgeries needed for best results. Similarly, patient and surgeon
expectations should be evaluated and addressed before replantation. Meticulous
microsurgical technique, comprehensive occupational therapy, and perseverance are
needed for success. Addressing these issues promotes a team rehabilitation to restore
function while getting the amputation patient back to productive position in society.
Darrell Brooks, Rudolf F. Buntic, Gabe M. Kind, Karin Schott, Gregory M. Buncke,
and Harry J. Buncke
Ring avulsion injury is classically believed to be one of the most challenging for the
reconstructive surgeon. Injury patterns include a spectrum from laceration to complete
amputation, with differential magnitude of injury to soft tissue, tendon, joint complex,
and bone. Although ring avulsion injury can result in devastating functional and
aesthetic loss to the hand, fear of even greater functional loss has made replantation
a relative contraindication for this complex injury. This article hopes to clarify the
pathomechanics and anatomy of ring avulsion, such that the elements of injury, which
lead to poor survival and poor function, can be adequately addressed in the surgical
plan.
Nonextremity Replantation: The Management of Amputations of the Facial Parts
Roberto L Flores, Alexes Hazen, Robert D. Galiano, Andrew M. Klapper,
and Jamie P. Levine
Successful nonextremity replantations, particularly of the facial anatomy and testicles,
are rare procedures, and only a handful of cases have been reported. This article reviews
the current literature in nonextremity replantations and representative cases performed
at the authors' institution. Certain underlying themes and problems are consistently
encountered in the surgical management of these cases. These are identified and
reviewed. Although the replantation of these body parts remains technically
challenging, all efforts should be made, when indicated, to repair these injuries
microsurgically, because it currently offers the best reconstructive solution for these
patients.
Extremity Reconstruction Usjmiit||QnjB«Jajnta^
Robert C. Russell, Michael W. Neumeister, Srdjan Andrei Ostric, and Nitin J. Engineer
After a severe digital or extremity injury, the replantation surgeon should always seek to
make the best use out of what tissue is available for reconstruction. Exercising sound
surgical judgment and being creative allow the surgeon to restore function to critical
areas of the hand or extremity by the judicious use of available tissues that would
otherwise be discarded. The use of "spare parts" should, therefore, always be considered
to facilitate digital or extremity reconstruction when routine replantation is not possible
or is likely to produce a poor functional result. The surgeon should always try to use
available nonreplantable tissue to preserve length, obtain soft tissue coverage, or most
importantly improve the function of remaining less injured digits. This article presents
several case studies that illustrate the principals of spare parts reconstruction performed
at the time of the initial debridement using nonreplantable tissue to provide coverage or
improve function.
^^ 223l.
Charles K. Lee and Gregory M. Buncke
Great toe to thumb transplantation offers the ideal reconstruction because it replaces the
absent thumb with nearly identical anatomy. Functional donor site morbidity is
minimal as compared with the aesthetic one; however, in comparison to the hand, the
functional and aesthetic gain is tremendous. Anatomic and operative details are
discussed along with preoperative and postoperative management. Postoperative
functional evaluation of the thumb and donor site is assessed. Forty years of experience
with this composite tissue transplantation has proven its status as the gold standard for
thumb reconstruction.
PART II: TRANSPLANTATION
Research and Events Leading to Facial Transplantation 233
John H. Barker, Niki Stamos, Allen Furr, Sean McGuire, Michael Cunningham,
Osborne Wiggins, Charles S. Brown, Brian Gander, Claudio Maldonado,
and Joseph C. Banis, Jr
Facial transplantation has long captured the interest and imagination of scientists, the
media, and the lay public. Facial transplantation could provide an excellent alternative
to current treatments for facial disfigurement caused by burns, trauma, cancer
extirpation, or congenital birth defects. This article discusses the major technical,
immunologie, psychosocial and ethical hurdles that have been overcome to bring facial
transplantation from an idea to a clinical reality by providing the reader with
a chronologic overview of the research and events that have led this exciting new
treatment into the clinical arena.
Maria Siemionow and Galip Agaoglu
The functional and aesthetic outcome following application of conventional
reconstructive procedures or prosthetic materials is not satisfactory, especially in
patients who have severe deformities and disabilities. Since the first successful hand
transplantation in France in 1998, composite tissue allograft transplantation has gained
a great deal of interest in the field of plastic surgery. It is obvious that composite tissue
allograft transplantation will improve patients' life quality, but this might be at the
expense of decreasing life expectancy. Currently, the main obstacle for composite tissue
allograft transplantation is the use of life long ¡mmunosuppression therapy because of
their well known side effects. In addition, the ethical, social, and psychologic issues are
raised when discussing face transplantation. The long term results of the recently
performed partial face transplantations will be critical to judge the future applications of
partial or total face transplantation.
Transplantation of the Hand, Face, and Composite Structures: Evolution and Current
Gordon R. Tobin, Warren C. Breidenbach, III, Diane J. Pidwell, Suzanne T. lldstad,
and Kadiyala V. Ravindra
This article reviews the world experience in the newly emerging field of composite tissue
allotransplantation. These allografts contain multiple tissues that are usually muscu
loskeletal structures with a skin or epithelial surface, such as hand, facial structures,
larynx, tongue, ear, knee/femur, abdominal wall, and penis. They represent a new
transplantation field, with only a 10 year experience and just over 50 clinical cases. This
review of the 10 year world experience found uniform technical success, immunologie
biology, and immunosuppression regimens very similar to solid organ transplants, and
success strongly correlated with adherence to guidelines for psychiatric screening,
thorough preparation of patient and families, intense postoperative monitoring, and
assurance of medication access. All failures reported have been caused by lapses in these
parameters. This early experience shows a great potential for application of these new
procedures to the most challenging reconstructive needs.
Bardia Amirlak, Ruben Gonzalez, Vijay Gorantla, Warren C. Breidenbach, III,
and Gordon R. Tobin
Successful hand transplantation depends upon an extensive, well coordinated system
with resources and experience in both upper extremity and transplant surgery. This
description of such a system is drawn from the experience of the Louisville, Kentucky,
Hand Transplant Program, which achieved the world's first successful hand transplant in
January 1999, and which is the only United States program to date. The personnel and
components of this system are outlined, with a detailed description of the roles,
responsibilities, and interaction between components. This system ensures optimal
management throughout recipient selection, psychiatric screening, education and
preparation, donor limb retrieval, transplant surgery, immunosuppression administra¬
tion and monitoring, and post transplant rehabilitation therapy. The lessons learned
from the experience of the Louisville team, and the experiences of the other teams
world wide, are presented to guide organization of future teams participating in this
pioneering endeavor.
Cellular Theraoies for Prolongation of CoiiiDOSite Tissue .Allograft Tfansplantation 291
Justin M. Sacks, Elaine K. Horibe, and W.P. Andrew Lee
Complex musculoskeletal defects resulting from cancer, congenital absence, and trauma
represent a unique reconstructive challenge. Autologous tissue is often unavailable to
reconstruct these deformities. Composite tissue allograft transplantation represents
a unique solution for these clinical problems. Face, hand, or limb transplants can be
performed in a single procedure. However, the use of chronic nonspecific systemic
immunosuppression can lead to side effects such as drug toxicity, opportunistic
infections, and malignancies. This article explores various cell based therapies that
represent promising modalities to reduce chronic immunosuppression and alter the
risk/benefit ratios for the prospect of composite tissue allograft transplantation.
The Immunology of C^njRojjjtjp TMMftJaOiiliOtation 303
Diane J. Pidwell and Carolyn Burns
Composite tissue allotransplantation holds great potential for reconstructive surgery.
That these procedures can be successful has been clearly demonstrated by the success of
hand, face, and larynx transplants around the world. Although the immunology of
composite tissue allotransplantation mirrors that of any allogeneic organ transplant,
there are several unique aspects to these grafts. This article reviews the immunology of
transplantation, histocompatibility testing for composite tissue allotransplantation,
graft rejection, immunosuppression, and specific immunologie considerations of
composite tissue allotransplantation.
Tissue Engineering: Bridging the Gap Between Replantation and Composite Tissue
MlSSBSEL, ¦mrnnr ir T .m.nr r.nr „r „ rnirn n,,.» TTTn.,,,,.»»»«.,, mmM mmmUJMmmumujuí mKj*MmmMm^*jML*m«aí3l
David M. Megee, Nada Berry, Robert C. Russell, and Michael W. Neumeister
This article explores issues related to tissue engineering and composite tissue allografts
that employ physiologic and anatomic autogenous replicates to restore tissue loss.
Composite tissue allotransplantation has become a controversial option for re¬
construction, most prominently for reconstruction involving the hand and, recently,
the face. While the side effect profile of systemic immunosuppression continues to
improve, the long term risks of immunosuppression leaves composite tissue allotrans¬
plantation a domain for cautious exploration. Meanwhile, tissue engineering could,
conceivably, be the gap between replantation and composite tissue allografts. Whereas
the perils of immunosuppression may limit the routine use of allografts, employing
constructions made of the patient's own cells negates the need for any antirejection
therapy. |
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indexdate | 2024-07-09T20:58:18Z |
institution | BVB |
isbn | 9781416042945 1416042946 |
language | English |
oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-015678483 |
oclc_num | 137217519 |
open_access_boolean | |
owner | DE-19 DE-BY-UBM |
owner_facet | DE-19 DE-BY-UBM |
physical | XIV S., S. 167 - 330 zahlr. Ill. |
publishDate | 2007 |
publishDateSearch | 2007 |
publishDateSort | 2007 |
publisher | Elsevier Saunders |
record_format | marc |
series | Clinics in plastic surgery |
series2 | Clinics in plastic surgery |
spelling | Replantation and transplantation guest ed. Ramazi O. Datiashvili Philadelphia [u.a.] Elsevier Saunders 2007 XIV S., S. 167 - 330 zahlr. Ill. txt rdacontent n rdamedia nc rdacarrier Clinics in plastic surgery 34,2 Reimplantation (Surgery) Surgery, Plastic Transplantation of organs, tissues, etc Datiashvili, Ramazi O. Sonstige oth Clinics in plastic surgery 34,2 (DE-604)BV000003656 34,2 HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=015678483&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
spellingShingle | Replantation and transplantation Clinics in plastic surgery Reimplantation (Surgery) Surgery, Plastic Transplantation of organs, tissues, etc |
title | Replantation and transplantation |
title_auth | Replantation and transplantation |
title_exact_search | Replantation and transplantation |
title_exact_search_txtP | Replantation and transplantation |
title_full | Replantation and transplantation guest ed. Ramazi O. Datiashvili |
title_fullStr | Replantation and transplantation guest ed. Ramazi O. Datiashvili |
title_full_unstemmed | Replantation and transplantation guest ed. Ramazi O. Datiashvili |
title_short | Replantation and transplantation |
title_sort | replantation and transplantation |
topic | Reimplantation (Surgery) Surgery, Plastic Transplantation of organs, tissues, etc |
topic_facet | Reimplantation (Surgery) Surgery, Plastic Transplantation of organs, tissues, etc |
url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=015678483&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
volume_link | (DE-604)BV000003656 |
work_keys_str_mv | AT datiashviliramazio replantationandtransplantation |