Histone deacetylases: transcriptional regulation and other cellular functions
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
Totowa, NJ
Humana Press
2006
|
| Schriftenreihe: | Cancer drug discovery and development
|
| Schlagworte: | |
| Online-Zugang: | Table of contents only Inhaltsverzeichnis |
| Beschreibung: | XI, 340 S. Ill., graph. Darst. |
| ISBN: | 1588294994 9781588294999 |
Internformat
MARC
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| 020 | |a 1588294994 |c alk. paper |9 1-58829-499-4 | ||
| 020 | |a 9781588294999 |9 978-1-58829-499-9 | ||
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| 245 | 1 | 0 | |a Histone deacetylases |b transcriptional regulation and other cellular functions |c ed. by Eric Verdin |
| 264 | 1 | |a Totowa, NJ |b Humana Press |c 2006 | |
| 300 | |a XI, 340 S. |b Ill., graph. Darst. | ||
| 336 | |b txt |2 rdacontent | ||
| 337 | |b n |2 rdamedia | ||
| 338 | |b nc |2 rdacarrier | ||
| 490 | 0 | |a Cancer drug discovery and development | |
| 650 | 7 | |a Antineoplásicos |2 larpcal | |
| 650 | 7 | |a Biologia celular |2 larpcal | |
| 650 | 7 | |a Enzimas |2 larpcal | |
| 650 | 7 | |a Neoplasias (pesquisa) |2 larpcal | |
| 650 | 4 | |a Histone deacetylase | |
| 650 | 4 | |a Cell cycle | |
| 650 | 4 | |a Enzymes | |
| 650 | 4 | |a Cancer |x Chemotherapy | |
| 650 | 4 | |a Histone Deacetylases |x physiology | |
| 650 | 4 | |a Cell Cycle |x drug effects | |
| 650 | 4 | |a Enzyme Repression |x physiology | |
| 650 | 4 | |a Histone Deacetylases |x antagonists & inhibitors | |
| 650 | 4 | |a Neoplasms |x drug therapy | |
| 650 | 4 | |a Sirtuins |x physiology | |
| 650 | 0 | 7 | |a Histon-Deacetylase |0 (DE-588)7564795-3 |2 gnd |9 rswk-swf |
| 689 | 0 | 0 | |a Histon-Deacetylase |0 (DE-588)7564795-3 |D s |
| 689 | 0 | |5 DE-604 | |
| 700 | 1 | |a Verdin, Eric |e Sonstige |4 oth | |
| 856 | 4 | |u http://www.loc.gov/catdir/toc/ecip063/2005031537.html |3 Table of contents only | |
| 856 | 4 | 2 | |m HBZ Datenaustausch |q application/pdf |u http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=015677503&sequence=000010&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |3 Inhaltsverzeichnis |
| 999 | |a oai:aleph.bib-bvb.de:BVB01-015677503 | ||
Datensatz im Suchindex
| _version_ | 1804136556845334528 |
|---|---|
| adam_text | Contents
Preface v
Contributors ix
Color Plates xi
I. Class I Histone Deacetylases
1 Histone Deacetylase 1
Dominique Meunier and Christian Seiser 3
2 Biochemistry of Multiprotein HDAC Complexes
Alejandro Vaquero, Michael Scher, and Danny Reinberg 23
3 The Biology of HDAC3
Edward Seto 61
4 The Biology of HDAC8, a Unique Class I Histone Deacetylase
David Waltregny and Vincent Castronovo 87
II. Class II Histone Deacetylases
5 Regulation of Muscle Gene Expression by Histone Deacetylases
Timothy A. McKinsey and Eric N. Olson 107
6 The Class Ha Histone Deacetylases: Functions and Regulation
Herbert G.Kasler and Eric Verdin 729
7 Histone Deacetylases in the Response to Misfolded Proteins
J. Andrew McKee and Tso Pang Yao 165
III. Class III Histone Deacetylases
8 Evolution of Sirtuins From Archaea to Vertebrates
Roy A. Frye 183
9 Structure of the Sir2 Family of NAD+ Dependent Histone/Protein
Deacetylases
Kehao Zhao and Ronen Marmorstein 203
10 The Enzymology of SIR2 Proteins
Margie T. Borra and John M. Denu 279
11 The Class III Protein Deacetylases: Homologs of Yeast Sir2p
Bjoern Schwer, Brian J. North, Nidhi Ahuja, Brett Marshall,
and Eric Verdin 237
vii
viii Contents
IV. Histone Deacetylase Inhibitors
12 HDAC Inhibitors: Discovery, Development, and Clinical Impacts
Akihiro Ito, Norikazu Nishino, andMinoru Yoshida 271
13 Cell Cycle Targets of Histone Deacetylase Inhibitors
Brian Gabrielli 299
14 HDAC Inhibitors: An Emerging Anticancer Therapeutic Strategy
PaulKwon, Meier Hsu, Dalia Cohen, and Peter Atadja 315
Index 333
|
| adam_txt |
Contents
Preface v
Contributors ix
Color Plates xi
I. Class I Histone Deacetylases
1 Histone Deacetylase 1
Dominique Meunier and Christian Seiser 3
2 Biochemistry of Multiprotein HDAC Complexes
Alejandro Vaquero, Michael Scher, and Danny Reinberg 23
3 The Biology of HDAC3
Edward Seto 61
4 The Biology of HDAC8, a Unique Class I Histone Deacetylase
David Waltregny and Vincent Castronovo 87
II. Class II Histone Deacetylases
5 Regulation of Muscle Gene Expression by Histone Deacetylases
Timothy A. McKinsey and Eric N. Olson 107
6 The Class Ha Histone Deacetylases: Functions and Regulation
Herbert G.Kasler and Eric Verdin 729
7 Histone Deacetylases in the Response to Misfolded Proteins
J. Andrew McKee and Tso Pang Yao 165
III. Class III Histone Deacetylases
8 Evolution of Sirtuins From Archaea to Vertebrates
Roy A. Frye 183
9 Structure of the Sir2 Family of NAD+ Dependent Histone/Protein
Deacetylases
Kehao Zhao and Ronen Marmorstein 203
10 The Enzymology of SIR2 Proteins
Margie T. Borra and John M. Denu 279
11 The Class III Protein Deacetylases: Homologs of Yeast Sir2p
Bjoern Schwer, Brian J. North, Nidhi Ahuja, Brett Marshall,
and Eric Verdin 237
vii
viii Contents
IV. Histone Deacetylase Inhibitors
12 HDAC Inhibitors: Discovery, Development, and Clinical Impacts
Akihiro Ito, Norikazu Nishino, andMinoru Yoshida 271
13 Cell Cycle Targets of Histone Deacetylase Inhibitors
Brian Gabrielli 299
14 HDAC Inhibitors: An Emerging Anticancer Therapeutic Strategy
PaulKwon, Meier Hsu, Dalia Cohen, and Peter Atadja 315
Index 333 |
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| illustrated | Illustrated |
| index_date | 2024-07-02T17:44:12Z |
| indexdate | 2024-07-09T20:58:17Z |
| institution | BVB |
| isbn | 1588294994 9781588294999 |
| language | English |
| lccn | 2005031537 |
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| physical | XI, 340 S. Ill., graph. Darst. |
| publishDate | 2006 |
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| publisher | Humana Press |
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| series2 | Cancer drug discovery and development |
| spelling | Histone deacetylases transcriptional regulation and other cellular functions ed. by Eric Verdin Totowa, NJ Humana Press 2006 XI, 340 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Cancer drug discovery and development Antineoplásicos larpcal Biologia celular larpcal Enzimas larpcal Neoplasias (pesquisa) larpcal Histone deacetylase Cell cycle Enzymes Cancer Chemotherapy Histone Deacetylases physiology Cell Cycle drug effects Enzyme Repression physiology Histone Deacetylases antagonists & inhibitors Neoplasms drug therapy Sirtuins physiology Histon-Deacetylase (DE-588)7564795-3 gnd rswk-swf Histon-Deacetylase (DE-588)7564795-3 s DE-604 Verdin, Eric Sonstige oth http://www.loc.gov/catdir/toc/ecip063/2005031537.html Table of contents only HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=015677503&sequence=000010&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Histone deacetylases transcriptional regulation and other cellular functions Antineoplásicos larpcal Biologia celular larpcal Enzimas larpcal Neoplasias (pesquisa) larpcal Histone deacetylase Cell cycle Enzymes Cancer Chemotherapy Histone Deacetylases physiology Cell Cycle drug effects Enzyme Repression physiology Histone Deacetylases antagonists & inhibitors Neoplasms drug therapy Sirtuins physiology Histon-Deacetylase (DE-588)7564795-3 gnd |
| subject_GND | (DE-588)7564795-3 |
| title | Histone deacetylases transcriptional regulation and other cellular functions |
| title_auth | Histone deacetylases transcriptional regulation and other cellular functions |
| title_exact_search | Histone deacetylases transcriptional regulation and other cellular functions |
| title_exact_search_txtP | Histone deacetylases transcriptional regulation and other cellular functions |
| title_full | Histone deacetylases transcriptional regulation and other cellular functions ed. by Eric Verdin |
| title_fullStr | Histone deacetylases transcriptional regulation and other cellular functions ed. by Eric Verdin |
| title_full_unstemmed | Histone deacetylases transcriptional regulation and other cellular functions ed. by Eric Verdin |
| title_short | Histone deacetylases |
| title_sort | histone deacetylases transcriptional regulation and other cellular functions |
| title_sub | transcriptional regulation and other cellular functions |
| topic | Antineoplásicos larpcal Biologia celular larpcal Enzimas larpcal Neoplasias (pesquisa) larpcal Histone deacetylase Cell cycle Enzymes Cancer Chemotherapy Histone Deacetylases physiology Cell Cycle drug effects Enzyme Repression physiology Histone Deacetylases antagonists & inhibitors Neoplasms drug therapy Sirtuins physiology Histon-Deacetylase (DE-588)7564795-3 gnd |
| topic_facet | Antineoplásicos Biologia celular Enzimas Neoplasias (pesquisa) Histone deacetylase Cell cycle Enzymes Cancer Chemotherapy Histone Deacetylases physiology Cell Cycle drug effects Enzyme Repression physiology Histone Deacetylases antagonists & inhibitors Neoplasms drug therapy Sirtuins physiology Histon-Deacetylase |
| url | http://www.loc.gov/catdir/toc/ecip063/2005031537.html http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=015677503&sequence=000010&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| work_keys_str_mv | AT verdineric histonedeacetylasestranscriptionalregulationandothercellularfunctions |