Growth hormone therapy in pediatrics: 20 years of KIGS ; 133 tables
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
Basel [u.a.]
Karger
2007
|
| Schlagworte: | |
| Online-Zugang: | Klappentext Inhaltsverzeichnis |
| Beschreibung: | VI, 519 S. Ill., graph. Darst. |
| ISBN: | 9783805582568 3805582560 |
Internformat
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| 245 | 1 | 0 | |a Growth hormone therapy in pediatrics |b 20 years of KIGS ; 133 tables |c ed.: Michael B. Ranke ... |
| 264 | 1 | |a Basel [u.a.] |b Karger |c 2007 | |
| 300 | |a VI, 519 S. |b Ill., graph. Darst. | ||
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Contents
Contributors
Preface
1
Patrick Wilton
2
Gary E. Butler
3
Kenji Fujieda, Toshiaki Tanaka
4
Anders
5
Michael
6
Growth Hormone Measurements
Susan R. Rose
6
Marthe
7
Angel
Agustín Romo
7
KIGS Data
Michael
8
Deficiency
Anders Juul
8
Database
Michael
9 Review Neuroimaging in
Mohamad Maghnie,
Paolo Tortori-Donati, Renata Lorini
10
the Start of Growth Hormone Therapy and the Response to Growth
Hormone
Herwig Frisch. 108
10
Michael
11
Edward
11
Hormone Deficiency: The KIGS Experience
Wayne S. Cutfield, Georgios Karagiannis, Edward O.
12
Growth Hormone Deficiency
Helena Gleeson, Peter E. Clayton
12
Serum Lipids and Quality of Life in Young Adults with Reconfirmed
Severe Growth Hormone Deficiency: The Combined KIGS and
KIMS Experiences
Mitchell E. Geffner, Peter
Charlotte
13
Michael
14
Primus E.
14
(Code No.
Michael
15
Craniopharyngioma: The KIGS Experience
David A. Price
16
Feyza Darendeliler
1?
Andreas Jostel, Stephen M. Shalet
17
(Code No.
Michael
f
and Lymphoma:The KIGS Experience
David A. Price,
VI
19 Review
Michel
19
Central Nervous System Tumours and Pituitary
Cell Histiocytosis within KIGS
Michael
20
Arthritis
Paul Czernichow
20
Juvenile Rheumatoid Arthritis
Edward
21
Dirk Schnabel. 296
21
Fibrosis
Edward
22
Response to Treatment
Jan M. Wit
22
Short Stature: KIGS Analysis of Factors Predicting Growth
Michael
Kerstin
23
Ron G.
23
Grown to Near Adult Height
Michael
24
Christopher J.H. Kelnar
24
Treatment in KIGS
Barto J. Otten,
25
Experience
Thomas
26
Ann
26
Prader-Willi Syndrome: The KIGS Experience
Marthe
VII
27 Review
for Gestational Age and with Silver-Russell Syndrome
Wayne S. Cutfield, Edward
27
David B.
28
Kidney Disease
Otto Mehls,
Burkhard Tönshoff,
29
The KIGS Approach
Michael
30
Patrick Wilton
31
Growth Delay
Brian Stabler, Louis E. Underwood
32
Fred
33
Jonathan C.K. Wells
34
Ulla Feldt-Rasmussen . 477
35
Ola Nilsson
36
Linda B. Johnston, Adrian J.L. Clark
Author Index
Subject Index
VIII
For
ing the use, efficacy and safety of growth hormone (GH) treatment in children with short stature
of varying origin.
This volume offers a comprehensive update of the continuing experiences in KIGS and is based on data
from more than
the basic auxological characteristics of patients and their response to GH treatment for a broad
spectrum of growth disorders. These include idiopathic GH deficiency, organic GH deficiency due
to a variety of causes such as congenital malformations and syndromes, genetic disorders or treat¬
ment for leukaemia or central nervous system tumours and short stature in children born small for
gestational age, specific syndromes and systemic disorders. Each growth disorder is also covered
by a review of relevant published data by international experts.
KIGS has also established itself as a primary source of information about adverse events during long-term
GH treatment in children. The recent analysis of KIGS data has revealed no new adverse drug reac¬
tions since the 10-year follow-up. Therefore, treatment with GH seems a low-risk intervention in
children and adolescents with various growth disorders.
The process of developing disease-specific growth response prediction models has been ongoing in KIGS
for many years. The available models are accurate, precise and have a relatively high degree of
predictive power, although further predictors of the growth response remain to be identified. The
KIGS prediction models can be applied prospectively to new patients, enabling their GH therapy
to be better tailored and monitored to achieve optimal growth, safety and cost outcomes.
The future of KIGS within the era of evidence-based medicine will continue to depend upon the quality
of the data reported. Therefore, the commitment of participating physicians will continue to be
a decisive element. The ongoing recognition of the importance of valid safety and efficacy infor¬
mation in the practice of paediatric endocrinology is exemplified by this valuable international
collaboration of clinicians and the pharmaceutical community. |
| adam_txt |
Contents
Contributors
Preface
1
Patrick Wilton
2
Gary E. Butler
3
Kenji Fujieda, Toshiaki Tanaka
4
Anders
5
Michael
6
Growth Hormone Measurements
Susan R. Rose
6
Marthe
7
Angel
Agustín Romo
7
KIGS Data
Michael
8
Deficiency
Anders Juul
8
Database
Michael
9 Review Neuroimaging in
Mohamad Maghnie,
Paolo Tortori-Donati, Renata Lorini
10
the Start of Growth Hormone Therapy and the Response to Growth
Hormone
Herwig Frisch. 108
10
Michael
11
Edward
11
Hormone Deficiency: The KIGS Experience
Wayne S. Cutfield, Georgios Karagiannis, Edward O.
12
Growth Hormone Deficiency
Helena Gleeson, Peter E. Clayton
12
Serum Lipids and Quality of Life in Young Adults with Reconfirmed
Severe Growth Hormone Deficiency: The Combined KIGS and
KIMS Experiences
Mitchell E. Geffner, Peter
Charlotte
13
Michael
14
Primus E.
14
(Code No.
Michael
15
Craniopharyngioma: The KIGS Experience
David A. Price
16
Feyza Darendeliler
1?
Andreas Jostel, Stephen M. Shalet
17
(Code No.
Michael
f
and Lymphoma:The KIGS Experience
David A. Price,
VI
19 Review
Michel
19
Central Nervous System Tumours and Pituitary
Cell Histiocytosis within KIGS
Michael
20
Arthritis
Paul Czernichow
20
Juvenile Rheumatoid Arthritis
Edward
21
Dirk Schnabel. 296
21
Fibrosis
Edward
22
Response to Treatment
Jan M. Wit
22
Short Stature: KIGS Analysis of Factors Predicting Growth
Michael
Kerstin
23
Ron G.
23
Grown to Near Adult Height
Michael
24
Christopher J.H. Kelnar
24
Treatment in KIGS
Barto J. Otten,
25
Experience
Thomas
26
Ann
26
Prader-Willi Syndrome: The KIGS Experience
Marthe
VII
27 Review
for Gestational Age and with Silver-Russell Syndrome
Wayne S. Cutfield, Edward
27
David B.
28
Kidney Disease
Otto Mehls,
Burkhard Tönshoff,
29
The KIGS Approach
Michael
30
Patrick Wilton
31
Growth Delay
Brian Stabler, Louis E. Underwood
32
Fred
33
Jonathan C.K. Wells
34
Ulla Feldt-Rasmussen . 477
35
Ola Nilsson
36
Linda B. Johnston, Adrian J.L. Clark
Author Index
Subject Index
VIII
For
ing the use, efficacy and safety of growth hormone (GH) treatment in children with short stature
of varying origin.
This volume offers a comprehensive update of the continuing experiences in KIGS and is based on data
from more than
the basic auxological characteristics of patients and their response to GH treatment for a broad
spectrum of growth disorders. These include idiopathic GH deficiency, organic GH deficiency due
to a variety of causes such as congenital malformations and syndromes, genetic disorders or treat¬
ment for leukaemia or central nervous system tumours and short stature in children born small for
gestational age, specific syndromes and systemic disorders. Each growth disorder is also covered
by a review of relevant published data by international experts.
KIGS has also established itself as a primary source of information about adverse events during long-term
GH treatment in children. The recent analysis of KIGS data has revealed no new adverse drug reac¬
tions since the 10-year follow-up. Therefore, treatment with GH seems a low-risk intervention in
children and adolescents with various growth disorders.
The process of developing disease-specific growth response prediction models has been ongoing in KIGS
for many years. The available models are accurate, precise and have a relatively high degree of
predictive power, although further predictors of the growth response remain to be identified. The
KIGS prediction models can be applied prospectively to new patients, enabling their GH therapy
to be better tailored and monitored to achieve optimal growth, safety and cost outcomes.
The future of KIGS within the era of evidence-based medicine will continue to depend upon the quality
of the data reported. Therefore, the commitment of participating physicians will continue to be
a decisive element. The ongoing recognition of the importance of valid safety and efficacy infor¬
mation in the practice of paediatric endocrinology is exemplified by this valuable international
collaboration of clinicians and the pharmaceutical community. |
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| illustrated | Illustrated |
| index_date | 2024-07-02T17:33:48Z |
| indexdate | 2024-08-14T00:51:57Z |
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| isbn | 9783805582568 3805582560 |
| language | English |
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| spelling | Growth hormone therapy in pediatrics 20 years of KIGS ; 133 tables ed.: Michael B. Ranke ... Basel [u.a.] Karger 2007 VI, 519 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Minderwuchs (DE-588)4170007-7 gnd rswk-swf Kind (DE-588)4030550-8 gnd rswk-swf Krankheit (DE-588)4032844-2 gnd rswk-swf Somatotropin (DE-588)4137446-0 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Kind (DE-588)4030550-8 s Krankheit (DE-588)4032844-2 s Somatotropin (DE-588)4137446-0 s DE-604 Minderwuchs (DE-588)4170007-7 s Ranke, Michael B. Sonstige (DE-588)118080806 oth Digitalisierung UB Regensburg application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=015652189&sequence=000003&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Klappentext Digitalisierung UB Regensburg application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=015652189&sequence=000004&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Growth hormone therapy in pediatrics 20 years of KIGS ; 133 tables Minderwuchs (DE-588)4170007-7 gnd Kind (DE-588)4030550-8 gnd Krankheit (DE-588)4032844-2 gnd Somatotropin (DE-588)4137446-0 gnd |
| subject_GND | (DE-588)4170007-7 (DE-588)4030550-8 (DE-588)4032844-2 (DE-588)4137446-0 (DE-588)4143413-4 |
| title | Growth hormone therapy in pediatrics 20 years of KIGS ; 133 tables |
| title_auth | Growth hormone therapy in pediatrics 20 years of KIGS ; 133 tables |
| title_exact_search | Growth hormone therapy in pediatrics 20 years of KIGS ; 133 tables |
| title_exact_search_txtP | Growth hormone therapy in pediatrics 20 years of KIGS ; 133 tables |
| title_full | Growth hormone therapy in pediatrics 20 years of KIGS ; 133 tables ed.: Michael B. Ranke ... |
| title_fullStr | Growth hormone therapy in pediatrics 20 years of KIGS ; 133 tables ed.: Michael B. Ranke ... |
| title_full_unstemmed | Growth hormone therapy in pediatrics 20 years of KIGS ; 133 tables ed.: Michael B. Ranke ... |
| title_short | Growth hormone therapy in pediatrics |
| title_sort | growth hormone therapy in pediatrics 20 years of kigs 133 tables |
| title_sub | 20 years of KIGS ; 133 tables |
| topic | Minderwuchs (DE-588)4170007-7 gnd Kind (DE-588)4030550-8 gnd Krankheit (DE-588)4032844-2 gnd Somatotropin (DE-588)4137446-0 gnd |
| topic_facet | Minderwuchs Kind Krankheit Somatotropin Aufsatzsammlung |
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| work_keys_str_mv | AT rankemichaelb growthhormonetherapyinpediatrics20yearsofkigs133tables |