Targeted therapies in cancer: with 25 tables
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
Berlin [u.a.]
Springer
2007
|
| Schriftenreihe: | Recent results in cancer research
176 |
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis Klappentext |
| Beschreibung: | XIV, 262 S. Ill., graph. Darst. |
| ISBN: | 9783540460909 354046090X |
Internformat
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Datensatz im Suchindex
| _version_ | 1804136414261018624 |
|---|---|
| adam_text | Contents
Parti Prediction of
1
in Individualized Therapy as a New Challenge for Tumour Pathology
Hans H. Kreipe,
2
Reinhold Schäfer,
3
Drug Resistance and New Anti-cancer Targets
Manfred
4
in Carcinomas of the Upper Gastrointestinal Tract
Heinz
5
Balázs Györffy
6
Hermann
7
in Colorectal Cancer
Ulrike
8
in Colorectal Cancer
Jan Stoehlmacher
Vllf Contents
9
Hans
Erich Solomayer,
Part
10
Agnieszka
11 Cetuximab:
Bert Hildebrandt, Philipp
Konrad Kolbie, Hanno
12
)an
13
of Rituximab, MY-lbritumomab Tiuxetan, and Alemtuzumab
Ihomas
14
in the Treatment of Cancer
tvana Zavrski, Christian Jakob, Martin Kaiser, Claudia Fleissner,
Ulrike Heider,
15
An Outlook
loannis Anagnostopoulos
16
iver Petersen
17
Receptors in Breast Cancer
Konrad Kolbie
Contents
Part 111 Prospects for Development
18
Ulrich Keilholz
19
Peter
20
Receptor-Like Reactivity
Andreas Ziegler, Pierre G. Coulie, Barbara Uchanska-Ziegler
21
Utz
Björn Steifen, Thomas Büchner, Wolfgang F.. Berdel
From its introduction, oncological chemotherapy has been encumbered by its poor
selectivity because most antiproliferative drugs are toxic not only to tumor cells
but also to important populations of the body s non-neoplastic cells. The resultant
problems with unwanted side effects are compounded by difficulties in predicting
the desired effectivity of chemotherapy in individual patients.
This unsatisfactory situation has driven intensive research and development
towards more specific and less toxic
Several results of these efforts have reached the clinic and an even greater number
are now in preclinical testing.
Common to all these targeted therapies is their interaction with defined molecules
present on cancer cells, which adds various degrees of increased selectivity to their
toxic effects. As a consequence, detecting the target molecule on tumors before
therapy holds great diagnostic potential for predicting the efficacy of the drug and
personalizing therapy.
This book aims to present translational scientists and clinicians with an integrated
critical view on the theories, mechanisms, problems and pitfalls of the targeted
therapy approach.
|
| adam_txt |
Contents
Parti Prediction of
1
in Individualized Therapy as a New Challenge for Tumour Pathology
Hans H. Kreipe,
2
Reinhold Schäfer,
3
Drug Resistance and New Anti-cancer Targets
Manfred
4
in Carcinomas of the Upper Gastrointestinal Tract
Heinz
5
Balázs Györffy
6
Hermann
7
in Colorectal Cancer
Ulrike
8
in Colorectal Cancer
Jan Stoehlmacher
Vllf Contents
9
Hans
Erich Solomayer,
Part
10
Agnieszka
11 Cetuximab:
Bert Hildebrandt, Philipp
Konrad Kolbie, Hanno
12
)an
13
of Rituximab, MY-lbritumomab Tiuxetan, and Alemtuzumab
'Ihomas
14
in the Treatment of Cancer
tvana Zavrski, Christian Jakob, Martin Kaiser, Claudia Fleissner,
Ulrike Heider,
15
An Outlook
loannis Anagnostopoulos
16
iver Petersen
17
Receptors in Breast Cancer
Konrad Kolbie
Contents
Part 111 Prospects for Development
18
Ulrich Keilholz
19
Peter
20
Receptor-Like Reactivity
Andreas Ziegler, Pierre G. Coulie, Barbara Uchanska-Ziegler
21
Utz
Björn Steifen, Thomas Büchner, Wolfgang F. Berdel
From its introduction, oncological chemotherapy has been encumbered by its poor
selectivity because most antiproliferative drugs are toxic not only to tumor cells
but also to important populations of the body's non-neoplastic cells. The resultant
problems with unwanted side effects are compounded by difficulties in predicting
the desired effectivity of chemotherapy in individual patients.
This unsatisfactory situation has driven intensive research and development
towards more specific and less toxic
Several results of these efforts have reached the clinic and an even greater number
are now in preclinical testing.
Common to all these targeted therapies is their interaction with defined molecules
present on cancer cells, which adds various degrees of increased selectivity to their
toxic effects. As a consequence, detecting the target molecule on tumors before
therapy holds great diagnostic potential for predicting the efficacy of the drug and
personalizing therapy.
This book aims to present translational scientists and clinicians with an integrated
critical view on the theories, mechanisms, problems and pitfalls of the targeted
therapy approach. |
| any_adam_object | 1 |
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| index_date | 2024-07-02T17:04:38Z |
| indexdate | 2024-07-09T20:56:01Z |
| institution | BVB |
| isbn | 9783540460909 354046090X |
| language | English |
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| series | Recent results in cancer research |
| series2 | Recent results in cancer research |
| spelling | Targeted therapies in cancer with 25 tables M. Dietel (ed.) Berlin [u.a.] Springer 2007 XIV, 262 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Recent results in cancer research 176 Krebs <Medizin> - Targeted drug delivery - Aufsatzsammlung Antineoplastic Agents Cancer Chemotherapy Drug targeting Neoplasms drug therapy Krebs Medizin (DE-588)4073781-0 gnd rswk-swf Targeted drug delivery (DE-588)4302415-4 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Krebs Medizin (DE-588)4073781-0 s Targeted drug delivery (DE-588)4302415-4 s DE-604 Dietel, Manfred 1949- Sonstige (DE-588)109410181 oth Recent results in cancer research 176 (DE-604)BV000000043 176 Digitalisierung UB Regensburg application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=015573661&sequence=000003&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis Digitalisierung UB Regensburg application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=015573661&sequence=000004&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA Klappentext |
| spellingShingle | Targeted therapies in cancer with 25 tables Recent results in cancer research Krebs <Medizin> - Targeted drug delivery - Aufsatzsammlung Antineoplastic Agents Cancer Chemotherapy Drug targeting Neoplasms drug therapy Krebs Medizin (DE-588)4073781-0 gnd Targeted drug delivery (DE-588)4302415-4 gnd |
| subject_GND | (DE-588)4073781-0 (DE-588)4302415-4 (DE-588)4143413-4 |
| title | Targeted therapies in cancer with 25 tables |
| title_auth | Targeted therapies in cancer with 25 tables |
| title_exact_search | Targeted therapies in cancer with 25 tables |
| title_exact_search_txtP | Targeted therapies in cancer with 25 tables |
| title_full | Targeted therapies in cancer with 25 tables M. Dietel (ed.) |
| title_fullStr | Targeted therapies in cancer with 25 tables M. Dietel (ed.) |
| title_full_unstemmed | Targeted therapies in cancer with 25 tables M. Dietel (ed.) |
| title_short | Targeted therapies in cancer |
| title_sort | targeted therapies in cancer with 25 tables |
| title_sub | with 25 tables |
| topic | Krebs <Medizin> - Targeted drug delivery - Aufsatzsammlung Antineoplastic Agents Cancer Chemotherapy Drug targeting Neoplasms drug therapy Krebs Medizin (DE-588)4073781-0 gnd Targeted drug delivery (DE-588)4302415-4 gnd |
| topic_facet | Krebs <Medizin> - Targeted drug delivery - Aufsatzsammlung Antineoplastic Agents Cancer Chemotherapy Drug targeting Neoplasms drug therapy Krebs Medizin Targeted drug delivery Aufsatzsammlung |
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