CtBP family proteins:
Gespeichert in:
Format: | Buch |
---|---|
Sprache: | English |
Veröffentlicht: |
New York, NY
Springer Science + Business Media
2007
Georgetown, Tex. Landes Bioscience / Eurekah.com |
Schriftenreihe: | Molecular biology intelligence unit
|
Schlagworte: | |
Online-Zugang: | Inhaltstext Inhaltsverzeichnis |
Beschreibung: | 121 S. Ill., graph. Darst. |
ISBN: | 9780387399713 0387399712 |
Internformat
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264 | 1 | |a Georgetown, Tex. |b Landes Bioscience / Eurekah.com | |
300 | |a 121 S. |b Ill., graph. Darst. | ||
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490 | 0 | |a Molecular biology intelligence unit | |
650 | 4 | |a DNA-Binding Proteins | |
650 | 4 | |a DNA-binding proteins | |
650 | 4 | |a Phosphoproteins | |
650 | 4 | |a Transcription factors | |
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Datensatz im Suchindex
_version_ | 1805088631995498496 |
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adam_text |
CONTENTS
Preface ii
1. CtBP Family Proteins: Unique Transcriptionai Regulators
in the Nucleus with Diverse Cytosolic Functions 1
G. Chinnadurai
CtBP Family Proteins 2
Nuclear Functions 4
Cytosolic Functions of CtBP 7
CtBPs in Central Nervous System Synapses 8
Control of Plant Microtubule Cytoskeleton 9
Role of CtBPs in Developmental Processes 9
Role in Oncogenesis and Apoptosis 10
2. Transcriptionai Repression by the CtBP Corepressor in Drosophila 18
Hitoshi Aihara, Lorena Perrone and Yutaka Nibu
Structure of the dCtBP Gene and Its Proteins 18
Factors Interacting with dCtBP 20
Short Range Transcriptionai Repression and dCtBP
in the Early Embryo 20
Histone Modifying Enzymes and dCtBP 23
dCtBP Interference with Hairy Bound Groucho 23
Multiple Repression Domains 24
Role of dCtBP in Signaling Pathways 24
Polycomb Group Proteins and dCtBP 24
3. CtBP and Hematopoietic Transcriptionai Regulators 28
Alexis Verger, Jose Perdomo and Merlin Crossley
CtBP Proteins during Development 28
CtBP Partnership with Hematopoietic Factors 31
CtBPs in Leukemogenesis 34
4. CtBP: A Link between Apoptosis and the Epithelial
Mesenchymal Transition 39
Steven M. Frisch
Discovery of CtBP's Phenotypic Properties in Human Tumor
Cells Using Ela as a Probe 39
5. The Significance of the CtBP AdElA Interaction during Viral
Infection and Transformation 44
Roger J.A. Grand, Claire Baker, Paola M. Barral, Rachel K. Bruton,
Julian Parkhill, Tadge Szestak and Philip H. Gallimore
The Phenorype of an Adenovirus 12 E1A CtBP Binding
Site Mutant 46
Infection of Human Cells with Adi2/6f Virus 51
Characterization of Rat Cells Transformed with Adl26fEl A 52
The Effect of siRNA Knock Down of CtBP Expression
on Adenovirus Infection 53
6. CtBP Proteins in Vertebrate Development 61
Jeffrey D. Hildebrand
CtBP Expression in Vertebrate Development 61
Redundant and Nonredundant Roles of CtBP 1 and QBP2
in Development 63
Developmental Genetics of CtBP 65
7. CtBP as a Redox Sensor in Transcriptional Repression 68
Qinghong Zhang, Clark C. Fjeld, Amanda C. Nottke
and Richard H. Goodman
Differential Binding of CtBP to NAD+ and NADH 68
NADH as Redox Indicator 71
NADH Dependent CtBP Binding to Repressors
in Transcription Repression 72
Biological Events Associated with NADH Level Fluctuation 74
Redox Sensitive Nuclear Transcription Regulators 74
8. CtBP Corepressor Complex—A Multi Enzyme Machinery
that Coordinates Chromatin Modifications 77
Yu Jiang Shi and Yang Shi
Six Enzymes/Potential Enzymes in the CtBP Super Complex 77
Other Components and Target Genes of the CtBP Super Complex . 79
Summary and Perspectives 80
9. Structural Determinants of CtBP Function 83
James R. Lundblad
CtBP: General Structural Considerations 84
Dinudeotide Binding by CtBP 86
Interaction of CtBP with Binding Partners 88
Summary and Unresolved Questions 90
10. CtBP3/BARS and Membrane Fission 93
Stefania Spanb, Cristina Hidalgo Carcedo andDaniela Corda
CtBP3/BARS as a Substrate of BFA Dependent ADP Ribosylation . 93
The CtBP3/BARS Fissioning Activity 95
CtBP3/BARS in Mitotic Fragmentation of the Golgi Complex 97
QBP3/BARS as a Dual Function Protein: The Molecular Switch 100
11. CtBPs as Synaptic Proteins 105
Susanne torn Dieck, Frank Schmitz andjohann Helmut Brandsta'tter
Chemical Synapses and Synaptic Transmission 105
Ribbon Synapses 105
The Novel CtBP Protein RIBEYE Is a Component
of Synaptic Ribbons 106
CtBPl Is Present at Both Ribbon and Conventional
Chemical Synapses 107
Diversity of CtBP Genes 107
Functional Considerations 107
12. A New Member of the CtBP/BARS Family from Plants:
Angustifolia 112
Hirokazu Tsukaya
Angustifolia—A Polarity Dependent Regulator of Leaf
Cell Expansion 112
Is AN a CtBP Like Corepressor? 114
Does AN Act as a Molecular Bridge as CtBPs? 114
IsANaHomologofBARS? 116
Conserved Function in Plants 116
Perspective 117
Index 119 |
adam_txt |
CONTENTS
Preface ii
1. CtBP Family Proteins: Unique Transcriptionai Regulators
in the Nucleus with Diverse Cytosolic Functions 1
G. Chinnadurai
CtBP Family Proteins 2
Nuclear Functions 4
Cytosolic Functions of CtBP 7
CtBPs in Central Nervous System Synapses 8
Control of Plant Microtubule Cytoskeleton 9
Role of CtBPs in Developmental Processes 9
Role in Oncogenesis and Apoptosis 10
2. Transcriptionai Repression by the CtBP Corepressor in Drosophila 18
Hitoshi Aihara, Lorena Perrone and Yutaka Nibu
Structure of the dCtBP Gene and Its Proteins 18
Factors Interacting with dCtBP 20
Short Range Transcriptionai Repression and dCtBP
in the Early Embryo 20
Histone Modifying Enzymes and dCtBP 23
dCtBP Interference with Hairy Bound Groucho 23
Multiple Repression Domains 24
Role of dCtBP in Signaling Pathways 24
Polycomb Group Proteins and dCtBP 24
3. CtBP and Hematopoietic Transcriptionai Regulators 28
Alexis Verger, Jose Perdomo and Merlin Crossley
CtBP Proteins during Development 28
CtBP Partnership with Hematopoietic Factors 31
CtBPs in Leukemogenesis 34
4. CtBP: A Link between Apoptosis and the Epithelial
Mesenchymal Transition 39
Steven M. Frisch
Discovery of CtBP's Phenotypic Properties in Human Tumor
Cells Using Ela as a Probe 39
5. The Significance of the CtBP AdElA Interaction during Viral
Infection and Transformation 44
Roger J.A. Grand, Claire Baker, Paola M. Barral, Rachel K. Bruton,
Julian Parkhill, Tadge Szestak and Philip H. Gallimore
The Phenorype of an Adenovirus 12 E1A CtBP Binding
Site Mutant 46
Infection of Human Cells with Adi2/6f Virus 51
Characterization of Rat Cells Transformed with Adl26fEl A 52
The Effect of siRNA Knock Down of CtBP Expression
on Adenovirus Infection 53
6. CtBP Proteins in Vertebrate Development 61
Jeffrey D. Hildebrand
CtBP Expression in Vertebrate Development 61
Redundant and Nonredundant Roles of CtBP 1 and QBP2
in Development 63
Developmental Genetics of CtBP 65
7. CtBP as a Redox Sensor in Transcriptional Repression 68
Qinghong Zhang, Clark C. Fjeld, Amanda C. Nottke
and Richard H. Goodman
Differential Binding of CtBP to NAD+ and NADH 68
NADH as Redox Indicator 71
NADH Dependent CtBP Binding to Repressors
in Transcription Repression 72
Biological Events Associated with NADH Level Fluctuation 74
Redox Sensitive Nuclear Transcription Regulators 74
8. CtBP Corepressor Complex—A Multi Enzyme Machinery
that Coordinates Chromatin Modifications 77
Yu Jiang Shi and Yang Shi
Six Enzymes/Potential Enzymes in the CtBP Super Complex 77
Other Components and Target Genes of the CtBP Super Complex . 79
Summary and Perspectives 80
9. Structural Determinants of CtBP Function 83
James R. Lundblad
CtBP: General Structural Considerations 84
Dinudeotide Binding by CtBP 86
Interaction of CtBP with Binding Partners 88
Summary and Unresolved Questions 90
10. CtBP3/BARS and Membrane Fission 93
Stefania Spanb, Cristina Hidalgo Carcedo andDaniela Corda
CtBP3/BARS as a Substrate of BFA Dependent ADP Ribosylation . 93
The CtBP3/BARS Fissioning Activity 95
CtBP3/BARS in Mitotic Fragmentation of the Golgi Complex 97
QBP3/BARS as a Dual Function Protein: The Molecular Switch 100
11. CtBPs as Synaptic Proteins 105
Susanne torn Dieck, Frank Schmitz andjohann Helmut Brandsta'tter
Chemical Synapses and Synaptic Transmission 105
Ribbon Synapses 105
The Novel CtBP Protein RIBEYE Is a Component
of Synaptic Ribbons 106
CtBPl Is Present at Both Ribbon and Conventional
Chemical Synapses 107
Diversity of CtBP Genes 107
Functional Considerations 107
12. A New Member of the CtBP/BARS Family from Plants:
Angustifolia 112
Hirokazu Tsukaya
Angustifolia—A Polarity Dependent Regulator of Leaf
Cell Expansion 112
Is AN a CtBP Like Corepressor? 114
Does AN Act as a Molecular Bridge as CtBPs? 114
IsANaHomologofBARS? 116
Conserved Function in Plants 116
Perspective 117
Index 119 |
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spellingShingle | CtBP family proteins DNA-Binding Proteins DNA-binding proteins Phosphoproteins Transcription factors Transcription, Genetic DNS-Bindungsproteine (DE-588)4150338-7 gnd |
subject_GND | (DE-588)4150338-7 |
title | CtBP family proteins |
title_auth | CtBP family proteins |
title_exact_search | CtBP family proteins |
title_exact_search_txtP | CtBP family proteins |
title_full | CtBP family proteins G. Chinnadurai |
title_fullStr | CtBP family proteins G. Chinnadurai |
title_full_unstemmed | CtBP family proteins G. Chinnadurai |
title_short | CtBP family proteins |
title_sort | ctbp family proteins |
topic | DNA-Binding Proteins DNA-binding proteins Phosphoproteins Transcription factors Transcription, Genetic DNS-Bindungsproteine (DE-588)4150338-7 gnd |
topic_facet | DNA-Binding Proteins DNA-binding proteins Phosphoproteins Transcription factors Transcription, Genetic DNS-Bindungsproteine |
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