Immunology of diabetes IV: progress in our understanding
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| Sprache: | English |
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Boston, Mass.
Blackwell
2006
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| Schriftenreihe: | Annals of the New York Academy of Sciences
1079 |
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| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | XV, 401 S. |
| ISBN: | 1573316415 |
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| adam_text | ANNALS OF THE NEW YORK ACADEMY OF SCIENCES
Volume 1079
October 2006
IMMUNOLOGY OF DIABETES IV
Progress in Our Understanding
Editors
Carani B. Sanjef.vi and Toshiaki Hanafusa
This volume is the result of a meeting entitled The 8th Meeting of the Immunology of
Diabetes Society, held on October 6 9, 2005 on Awaji Island, Japan.
CONTENTS
Overview. By C.B. Sanjeevi and T. Hanafusa xv
Part I. Special Papers
The Type 1 Diabetes Genetics Consortium. By Stephen S. Rich,
Patrick Concannon, Henry Erlich, Cecile Julier, Grant Morahan,
Jorn Nerup, Flemming Pociot, and John A. Todd 1
A Mini Meta Analysis of Studies on CD4+CD25+ T cells in Human Type 1
Diabetes: Report of the Immunology of Diabetes Society T Cell
Workshop. By Timothy I.M. Tree, Bart O. Roep,
and Mark Peakman 9
HLA Class I Epitope Discovery in Type 1 Diabetes: Independent
and Reproducible Identification of Proinsulin Epitopes of CD8
T Cells—Report of the IDS T Cell Workshop Committee. By
Gabrielle G.M. Pinkse, Christian Boitard, Timothy I.M. Tree,
Mark Peakman, and Bart O. Roep 19
Part II. Diabetes in Asia
Genetics of Fulminant Type 1 Diabetes. By Em Kawasaki and Katslmi
Eguchi 24
Why Is Type 1 Diabetes Uncommon in Asia? By Yongsoo Park 31
Association of SUMO4, as a Candidate Gene for IDDM5, with Susceptibility
to Type 1 Diabetes in Asian Populations. By Shinsuke Noso,
Hiroshi Ikegami, Tomomi Fujisawa, Yumiko Kawabata,
Katsuaki Asano, Yoshihisa Hiromine, Shigetaka Sugihara,
Inkyu Lee, Eui Kawasaki, Takuya Awata, and Toshio Ogihara 41
The Gene for Human IL 21 and Genetic Susceptibility to Type 1 Diabetes in the
Japanese. By Katsuaki Asano, Hiroshi Ikegami, Tomomi Fujisawa,
Yumiko Kawabata, Shinsuke Noso, Yoshihisa Hiromine,
and Toshio Ogihara 47
Genetics of Type 1 Diabetes: Similarities and Differences between Asian and
Caucasian Populations. By Hiroshi Ikegami, Tomomi Fujisawa,
Yumiko Kawabata, Shinsuke Noso, and Toshio Ogiharaa 51
Part III. Latent Autoimmune Diabetes in Adults
Immunopathological and Genetic Features in Slowly Progressive
Insulin Dependent Diabetes Mellitus and Latent Autoimmune Diabetes in
Adults. By Tetsuro Kobayashi, Shoichiro Tanaka, Norikazu Harii,
Kaoru Aida, Hiroki Shimura, Masayuki Ohmori, Masahiro Kanesige,
Akira Shimada, and Taro Maruyama 60
Genes Influencing Innate and Acquired Immunity in Type 1 Diabetes
and Latent Autoimmune Diabetes in Adults. By Carani B. Sanjeevi .... 67
Progression of Autoimmune Diabetes: Slowly Progressive Insulin Dependent
Diabetes Mellitus or Latent Autoimmune Diabetes of Adult. By
Huriya Beyan, Thomas Ola, R. David, and G. Leslie 81
Immunomodulation for the Prevention of SPIDDM and LADA. By P. Pozzilli
AND C. GUGLIELMI 90
Part IV. Animal Models
Heightened Interferon a/(3 Response Causes Myeloid Cell Dysfunction
and Promotes T1D Pathogenesis in NOD Mice. By Ruihua Peng,
Edward Paek, Chanqing Q. Xia, Nathan Tennyson,
and Michael J. Clare Salzler
Immunolocalization of Monocyte Chemoattractant Protein 1 in Islets of NOD
Mice during Cyclophosphamide Administration. By Shiva Reddy,
Yan Bai, Elizabeth Robinson, and Jacqueline Ross 103
Young NOD Mice Show Increased Diabetes Sensitivity to Low Doses of
Streptozotocin. By Shiva Reddy, Mike Chang,
and Elizabeth Robinson 109
Contribution of Class III MHC to Susceptibility to Type 1 Diabetes in the
NOD Mouse. Bv Kaori Yamaji, Hiroshi Ikegami, Tomomi Fujisawa,
Shinsuke Noso, Koji Nojima, Naru Babaya, Michiko Itoi Babaya,
Misato Kobayashi, Yoshihisa Hiromine, Susumu Makino,
and Toshio Ogiharaa 114
MHC Linked Susceptibility to Type 1 Diabetes in the NOD Mouse: Further
Localization of Iddl6 by Subcongenic Analysis. By Tomomi Fujisawa,
Hiroshi Ikegami, Shinsuke Noso, Kaori Yamaji, Koji Nojima,
Naru Babaya, Michiko Itoi Babaya, Yoshihisa Hiromine,
Misato Kobayashi, Susumu Makino, and Toshio Ogiharaa 118
Long Term Prevention of Diabetes and Marked Suppression of Insulin
Autoantibodies and Insulitis in Mice Lacking Native Insulin B9 23
Sequence. By M. Nakayama, N. Babaya, D. Miao, R. Gianani, E. Liu,
J.F. Elliott, and G.S. Eisenbarth 122
Eicosanoid Imbalance in the NOD Mouse Is Related to a Dysregulation in
Soluble Epoxide Hydrolase and 15 PGDH Expression. By
Michelle Rodriguez and Michael Clare Salzler 130
Pancreatic Autoimmunity Induction with Insulin B:9 23 Peptide and Viral
Mimics in the NZB Mouse. By Devasenan Devendra, Dongmei Miao,
Maki Nakayama, George S. Eisenbarth, and Edwin Liu 135
Viruses Cause Type 1 Diabetes in Animals. By Ji Won Yoon
and Hee Sook. Jun 138
Characterization of PAF AH Ibl in NOD Mice: PAF AH May Not Be a
Candidate Gene of the Diabetes Susceptibility Idd4.1 Locus. By
Qing Sheng Mi, Li Zhou, Marsha Grattan, Zai Zhao Wang,
m. slvilotti, jlng xlang she, and terry l. delov1tch 147
Peptide Pulsed Immature Dendritic Cells Reduce Response to (3 Cell Target
Antigens and Protect NOD Recipients from Type I Diabetes. By
Jeannette Lo, Rui Hua Peng, Tolga Barker, Chang Qing Xia,
and Michael J. Clare Salzler 153
New Members of the Interleukin 12 Family of Cytokines: IL 23 and IL 27
Modulate Autoimmune Diabetes. By E.P.K. Mensah Brown, A. Shahin,
M. Al Shamsi, and M.L. Lukic .. 157
Part V. T Cells
Glutamic Acid Decarboxylase Specific CD4+ Regulatory T Cells. By
Chih Pin Liu 161
Metabolism Genes Are among the Differentially Expressed Ones Observed in
Lymphomononuclear Cells of Recently Diagnosed Type 1 Diabetes
Mellitus Patients. By Diane M. Rassi, Cristina M. Junta,
Ana Lucia Fachin, Paula Sandrin Garcia, Stefano Mello,
Marcia M.C. Marques, Ana Paula M. Fernandes, Maria Cristina
Foss Freitas, Milton C. Foss, Elza T. Sakamoto Hojo,
Geraldo A.S. Passos, and Eduardo A. Donadi 171
In Vitro TNF a and IL 6 Production by Adherent Peripheral Blood
Mononuclear Cells Obtained from Type 1 and Type 2 Diabetic Patients
Evaluated according to the Metabolic Control. By Maria Cristina
Foss Freitas, Norma Tiraboschi Foss, Eduardo Antonio Donadi,
and Milton Cesar Foss 177
T Cell Immunity to Glutamic Acid Decarboxylase in Fulminant Type 1
Diabetes without Significant Elevation of Serum Amylase. Bv
Kanemi Aoki, Matsuo Taniyama, Chieko Nagayama, Yoichi Oikawa,
and akira shimada 181
Expression Levels of CXC Chemokine Receptors 3 Are Associated with
Clinical Phenotype of Type 1 Diabetes. By Satoru Yamada,
Yoichi Oikawa, Gen Sakai, Yoshihito Atsumi, Taro Maruyama,
and Akira Shimada 186
HLA Class I Epitope Discovery in Type 1 Diabetes. By Peter Van Endert,
Yousra Hassainya, Vivian Lindo, Jean Marie Bach, Philippe Blancou,
Francois Lemonnier, and Roberto Mallone 190
Upregulation of Foxp3 Expression in Mouse and Human Treg Is IL 2 / STAT5
Dependent: Implications for the NOD STAT5B Mutation in Diabetes
Pathogenesis. By Matthew R. Murawski, Sally A. Litherland,
Michael J. Clare Salzler, and Abdoreza Davoodi Semiromi 198
Normal T Cell Development in the Absence of Thymic Insulin Expression. By
Maria Carlsen and Corrado M. Cilio 205
Part VI. Autoantibodies
Antigenic Determinants to GAD Autoantibodies in Patients with Type 1
Diabetes with and without Autoimmune Thyroid Disease. By
Hyewon Park, Liping Yu, Taewha Kim, Boyoun Cho, Jungoo Kang,
and yongsoo park 213
TSH Receptor Antibodies in Subjects with Type 1 Diabetes Mellitus. By
Ambika G. Unnikrishnan, Velayutham Kumaravel, Vasantha Nair,
Ananth Rao, Rohini V Jayakumar, Harish Kumar,
and Carani B. Sanjeevi 220
Time Resolved Fluorescence Imaging of Islet Cell Autoantibodies. By
Pauli Vuorinen, Maris Rulli, Ari Kuusisto, Satu Simell,
Tuula Simell Tero Vahlberg, Jorma Ilonen, Heikki Hyoty,
Mikael Knip, and Olli Simell 226
MHC Class I Chain Related Gene A Is Associated with IA2 and IAA but Not
GAD in Swedish Type 1 Diabetes Mellitus. By Manu Gupta,
Jinko Graham, Brian McNeeny, Marian Zarghami,
Mona Landin Olsson, William A. Hagopian, Jerry Palmer,
Ake Lernmark, and Carani B. Sanjeevi 229
Part VII. Genetics
Predominance of the Group A Killer Ig Like Receptor Haplotypes in Korean
Patients with T1D. By Yongsoo Park, Heejin Choi, Hyewon Park,
Sukyung Park, Eun Kyung Yoo, Dukhee Kim,
and Carani B. Sanjeevi 240
Frequency of CTLA 4 Gene CT60 Polymorphism May Not Be Affected by
Vitamin D Receptor Gene Bsm I Polymorphism or HLA DR9 in
Autoimmune Related Type 1 Diabetes in the Japanese. By
Yasuhiko Kanazawa, Yoshiko Motohashi, Satoru Yamada,
yoichi olkawa, toshikatsu shigihara, yoshiaki okubo,
Taro Maruyama, and Akira Shimada 251
Genetic and Functional Evidence Supporting SUMO4 as a Type 1 Diabetes
Susceptibility Gene. By Cong Yi Wang, Robert Podolsky,
and Jin Xiong She 257
No Association of TLR2 and TLR4 Polymorphisms with Type I Diabetes
Mellitus in the Basque Population. By Izortze Santin, Jose Ramon Bilbao,
Guiomar Perez De Nanclares, Begona Calvo, and Luis Castano ... 268
Association of SUMO4 M55V Polymorphism with Autoimmune Diabetes
in Latvian Patients. By Saikiran K. Sedimbi, Arun Shastry,
Yongsoo Park, Ingrida Rumba, and Carani B. Sanjeevi 273
A Second Component of HLA Linked Susceptibility to Type 1 Diabetes
Maps to Class I Region. By Yumiko Kawabata, Hiroshi Ikegami,
Tomomi Fujisawa, Shinsuke Noso, Katsuaki Asano,
yoshih1sa hlromine, and tosh1o ogihara 278
Molecular Scanning of the Gene for Programmed Cell Death 1 (PDCD 1) as a
Candidate for Type 1 Diabetes Susceptibility. By Yoshihisa Hiromine,
Hiroshi Ikegami, Tomomi Fujisawa, Yumiko Kawabata, Shinsuke Noso,
Kaori Yamaji, Katsuaki Asano, and Toshio Ogiharaa 285
Genetic Determinants of Type 1 Diabetes across Populations. By
Mohamed M. Jahromi and George S. Eisenbarth 289
TNFa e Microsatellite, HLA DRB1 and DQB1 Alleles and Haplotypes in
Brazilian Patients Presenting Recently Diagnosed Type 1 Diabetes
Mellitus. By Diane M. Rassi, Isabela J. Wastowski, Renata T. Simoes,
Sandra Rodrigues, Neife N.H.S. Deghaide, Celso T. Mendes Junior,
Aguinaldo L. Simoes, C.P. Soares, Geraldo A.S. Passos,
and Eduardo A. Donadi 300
Is HLA Class II Profile Relevant for the Study of Large Scale Differentially
Expressed Genes in Type 1 Diabetes Mellitus Patients? By
Diane M. Rassi, Cristina M. Junta, Ana L. Fachin,
Paula Sandrin Garcia, Stephano S. Mello, Ana P.M. Fernandes,
Neife N.H.S. Deghaide, Maria C. Foss Freitas, Milton C. Foss,
Elza T. Sakamoto Hojo, Geraldo A.S. Passos,
and Eduardo A. Donadi 305
Part VIII. Prediction and Prevention
Feasibility of a Type 1 Diabetes Primary Prevention Trial Using 2000 IU
Vitamin D3 in Infants from the General Population with Increased
HLA Associated Risk. By Brandy A. Wicklow
and Shayne P. Taback 310
Interleukin 10 Plasmid Construction and Delivery for the Prevention of Type 1
Diabetes. By Minhyung Lee, Hyewon Park, Jeehee Yoln, Eun Taex Oh,
KYUNGSOO KO, SUNGWAN KlM, AND YONGSOO PARK 313
TEDDY The Environmental Determinants of Diabetes in the Young. By
William A. Hagopian, Ake Lernmark, Marian J. Rewers,
Olli G. Simell, Jin Xiong She, Anettf G. Ziegler, Jeffrey P. Krisc her,
and Beena Akolkar 320
Protection from Type 1 Diabetes by Vitamin D Receptor Haplotypes. Si
Elizabeth Ramos Lopez, Thomas Jansen, Vytautas Ivaskeyktus.
Heinrr h Kahles, Christian Klepzig, Johannes Oldenburg,
and Klaus Badf.nhoop 327
Living Donor Islet Transplantation, the Alternative Approach to Overcome the
Obstacles Limiting Transplant. By Yasuhiro Iwanaga,
Shinichi Matslmoto, Teru Okitsu. Hiroflmi Noguchi. Hideo Nagata.
YUKIHIDE YONEKAWA, YUKHIRO YAMADA, KaZUHITO FUKUDA.
Katsushi Tsukiyama, and Koichi Tanaka 335
DiaPep277 Preserves Endogenous Insulin Production by Immunomodulation
in Type 1 Diabetes. By Dana Elias, Ann Avron, Merana Tamir,
AND ITAMAR RAZ 340
Cord Blood Islet Autoantibodies Are Related to Stress in the Mother during
Pregnancy. By Barbro Lernmark, Kristian Lynch, Ake Lernmark,
and The DiPiS Study Group 345
Is It Dietary Insulin? By Outi Vaarala 350
Probiotics for the Prevention of Beta Cell Autoimmunity in Children at
Genetic Risk of Type 1 Diabetes—the PRODIA Study. By
Martin Ljungberg, Riita Korpela, Jorma Ilonen,
Johnny Ludvigsson, and Outi Vaarala 360
Thiazolidinediones May Not Reduce Diabetes Incidence in Type 1 Diabetes. By
Toshikatsu Shigihara, Yoshiaki Okubo, Yasuhiko Kanazawa,
Yoichi Oikawa, and Akira Shimada 365
Mechanisms Mediating Anti CD3 Antibody Efficacy: Insights from
a Mathematical Model of Type 1 Diabetes. By Daniel L. Young,
Saroja Ramanujan, Huub T.C. Kreuwel, Chan Chung Whiting,
Kapil G. Gadkar, and Lisl K.M. Shoda 369
Why Diabetes Incidence Increases—A Unifying Theory. By Johnny
Ludvigsson 374
Overcoming the Challenges Now Limiting Islet Transplantation: A Sequential,
Integrated Approach. By Antonello Pileggi, Lorenzo Cobianchi,
Luca Inverardi, and Camillo Ricordi 383
Index of Contributors 399
|
| adam_txt |
ANNALS OF THE NEW YORK ACADEMY OF SCIENCES
Volume 1079
October 2006
IMMUNOLOGY OF DIABETES IV
Progress in Our Understanding
Editors
Carani B. Sanjef.vi and Toshiaki Hanafusa
This volume is the result of a meeting entitled The 8th Meeting of the Immunology of
Diabetes Society, held on October 6 9, 2005 on Awaji Island, Japan.
CONTENTS
Overview. By C.B. Sanjeevi and T. Hanafusa xv
Part I. Special Papers
The Type 1 Diabetes Genetics Consortium. By Stephen S. Rich,
Patrick Concannon, Henry Erlich, Cecile Julier, Grant Morahan,
Jorn Nerup, Flemming Pociot, and John A. Todd 1
A Mini Meta Analysis of Studies on CD4+CD25+ T cells in Human Type 1
Diabetes: Report of the Immunology of Diabetes Society T Cell
Workshop. By Timothy I.M. Tree, Bart O. Roep,
and Mark Peakman 9
HLA Class I Epitope Discovery in Type 1 Diabetes: Independent
and Reproducible Identification of Proinsulin Epitopes of CD8
T Cells—Report of the IDS T Cell Workshop Committee. By
Gabrielle G.M. Pinkse, Christian Boitard, Timothy I.M. Tree,
Mark Peakman, and Bart O. Roep 19
Part II. Diabetes in Asia
Genetics of Fulminant Type 1 Diabetes. By Em Kawasaki and Katslmi
Eguchi 24
Why Is Type 1 Diabetes Uncommon in Asia? By Yongsoo Park 31
Association of SUMO4, as a Candidate Gene for IDDM5, with Susceptibility
to Type 1 Diabetes in Asian Populations. By Shinsuke Noso,
Hiroshi Ikegami, Tomomi Fujisawa, Yumiko Kawabata,
Katsuaki Asano, Yoshihisa Hiromine, Shigetaka Sugihara,
Inkyu Lee, Eui Kawasaki, Takuya Awata, and Toshio Ogihara 41
The Gene for Human IL 21 and Genetic Susceptibility to Type 1 Diabetes in the
Japanese. By Katsuaki Asano, Hiroshi Ikegami, Tomomi Fujisawa,
Yumiko Kawabata, Shinsuke Noso, Yoshihisa Hiromine,
and Toshio Ogihara 47
Genetics of Type 1 Diabetes: Similarities and Differences between Asian and
Caucasian Populations. By Hiroshi Ikegami, Tomomi Fujisawa,
Yumiko Kawabata, Shinsuke Noso, and Toshio Ogiharaa 51
Part III. Latent Autoimmune Diabetes in Adults
Immunopathological and Genetic Features in Slowly Progressive
Insulin Dependent Diabetes Mellitus and Latent Autoimmune Diabetes in
Adults. By Tetsuro Kobayashi, Shoichiro Tanaka, Norikazu Harii,
Kaoru Aida, Hiroki Shimura, Masayuki Ohmori, Masahiro Kanesige,
Akira Shimada, and Taro Maruyama 60
Genes Influencing Innate and Acquired Immunity in Type 1 Diabetes
and Latent Autoimmune Diabetes in Adults. By Carani B. Sanjeevi . 67
Progression of Autoimmune Diabetes: Slowly Progressive Insulin Dependent
Diabetes Mellitus or Latent Autoimmune Diabetes of Adult. By
Huriya Beyan, Thomas Ola, R. David, and G. Leslie 81
Immunomodulation for the Prevention of SPIDDM and LADA. By P. Pozzilli
AND C. GUGLIELMI 90
Part IV. Animal Models
Heightened Interferon a/(3 Response Causes Myeloid Cell Dysfunction
and Promotes T1D Pathogenesis in NOD Mice. By Ruihua Peng,
Edward Paek, Chanqing Q. Xia, Nathan Tennyson,
and Michael J. Clare Salzler "
Immunolocalization of Monocyte Chemoattractant Protein 1 in Islets of NOD
Mice during Cyclophosphamide Administration. By Shiva Reddy,
Yan Bai, Elizabeth Robinson, and Jacqueline Ross 103
Young NOD Mice Show Increased Diabetes Sensitivity to Low Doses of
Streptozotocin. By Shiva Reddy, Mike Chang,
and Elizabeth Robinson 109
Contribution of Class III MHC to Susceptibility to Type 1 Diabetes in the
NOD Mouse. Bv Kaori Yamaji, Hiroshi Ikegami, Tomomi Fujisawa,
Shinsuke Noso, Koji Nojima, Naru Babaya, Michiko Itoi Babaya,
Misato Kobayashi, Yoshihisa Hiromine, Susumu Makino,
and Toshio Ogiharaa 114
MHC Linked Susceptibility to Type 1 Diabetes in the NOD Mouse: Further
Localization of Iddl6 by Subcongenic Analysis. By Tomomi Fujisawa,
Hiroshi Ikegami, Shinsuke Noso, Kaori Yamaji, Koji Nojima,
Naru Babaya, Michiko Itoi Babaya, Yoshihisa Hiromine,
Misato Kobayashi, Susumu Makino, and Toshio Ogiharaa 118
Long Term Prevention of Diabetes and Marked Suppression of Insulin
Autoantibodies and Insulitis in Mice Lacking Native Insulin B9 23
Sequence. By M. Nakayama, N. Babaya, D. Miao, R. Gianani, E. Liu,
J.F. Elliott, and G.S. Eisenbarth 122
Eicosanoid Imbalance in the NOD Mouse Is Related to a Dysregulation in
Soluble Epoxide Hydrolase and 15 PGDH Expression. By
Michelle Rodriguez and Michael Clare Salzler 130
Pancreatic Autoimmunity Induction with Insulin B:9 23 Peptide and Viral
Mimics in the NZB Mouse. By Devasenan Devendra, Dongmei Miao,
Maki Nakayama, George S. Eisenbarth, and Edwin Liu 135
Viruses Cause Type 1 Diabetes in Animals. By Ji Won Yoon
and Hee Sook. Jun 138
Characterization of PAF AH Ibl in NOD Mice: PAF AH May Not Be a
Candidate Gene of the Diabetes Susceptibility Idd4.1 Locus. By
Qing Sheng Mi, Li Zhou, Marsha Grattan, Zai Zhao Wang,
m. slvilotti, jlng xlang she, and terry l. delov1tch 147
Peptide Pulsed Immature Dendritic Cells Reduce Response to (3 Cell Target
Antigens and Protect NOD Recipients from Type I Diabetes. By
Jeannette Lo, Rui Hua Peng, Tolga Barker, Chang Qing Xia,
and Michael J. Clare Salzler 153
New Members of the Interleukin 12 Family of Cytokines: IL 23 and IL 27
Modulate Autoimmune Diabetes. By E.P.K. Mensah Brown, A. Shahin,
M. Al Shamsi, and M.L. Lukic .' 157
Part V. T Cells
Glutamic Acid Decarboxylase Specific CD4+ Regulatory T Cells. By
Chih Pin Liu 161
Metabolism Genes Are among the Differentially Expressed Ones Observed in
Lymphomononuclear Cells of Recently Diagnosed Type 1 Diabetes
Mellitus Patients. By Diane M. Rassi, Cristina M. Junta,
Ana Lucia Fachin, Paula Sandrin Garcia, Stefano Mello,
Marcia M.C. Marques, Ana Paula M. Fernandes, Maria Cristina
Foss Freitas, Milton C. Foss, Elza T. Sakamoto Hojo,
Geraldo A.S. Passos, and Eduardo A. Donadi 171
In Vitro TNF a and IL 6 Production by Adherent Peripheral Blood
Mononuclear Cells Obtained from Type 1 and Type 2 Diabetic Patients
Evaluated according to the Metabolic Control. By Maria Cristina
Foss Freitas, Norma Tiraboschi Foss, Eduardo Antonio Donadi,
and Milton Cesar Foss 177
T Cell Immunity to Glutamic Acid Decarboxylase in Fulminant Type 1
Diabetes without Significant Elevation of Serum Amylase. Bv
Kanemi Aoki, Matsuo Taniyama, Chieko Nagayama, Yoichi Oikawa,
and akira shimada 181
Expression Levels of CXC Chemokine Receptors 3 Are Associated with
Clinical Phenotype of Type 1 Diabetes. By Satoru Yamada,
Yoichi Oikawa, Gen Sakai, Yoshihito Atsumi, Taro Maruyama,
and Akira Shimada 186
HLA Class I Epitope Discovery in Type 1 Diabetes. By Peter Van Endert,
Yousra Hassainya, Vivian Lindo, Jean Marie Bach, Philippe Blancou,
Francois Lemonnier, and Roberto Mallone 190
Upregulation of Foxp3 Expression in Mouse and Human Treg Is IL 2 / STAT5
Dependent: Implications for the NOD STAT5B Mutation in Diabetes
Pathogenesis. By Matthew R. Murawski, Sally A. Litherland,
Michael J. Clare Salzler, and Abdoreza Davoodi Semiromi 198
Normal T Cell Development in the Absence of Thymic Insulin Expression. By
Maria Carlsen and Corrado M. Cilio 205
Part VI. Autoantibodies
Antigenic Determinants to GAD Autoantibodies in Patients with Type 1
Diabetes with and without Autoimmune Thyroid Disease. By
Hyewon Park, Liping Yu, Taewha Kim, Boyoun Cho, Jungoo Kang,
and yongsoo park 213
TSH Receptor Antibodies in Subjects with Type 1 Diabetes Mellitus. By
Ambika G. Unnikrishnan, Velayutham Kumaravel, Vasantha Nair,
Ananth Rao, Rohini V Jayakumar, Harish Kumar,
and Carani B. Sanjeevi 220
Time Resolved Fluorescence Imaging of Islet Cell Autoantibodies. By
Pauli Vuorinen, Maris Rulli, Ari Kuusisto, Satu Simell,
Tuula Simell Tero Vahlberg, Jorma Ilonen, Heikki Hyoty,
Mikael Knip, and Olli Simell 226
MHC Class I Chain Related Gene A Is Associated with IA2 and IAA but Not
GAD in Swedish Type 1 Diabetes Mellitus. By Manu Gupta,
Jinko Graham, Brian McNeeny, Marian Zarghami,
Mona Landin Olsson, William A. Hagopian, Jerry Palmer,
Ake Lernmark, and Carani B. Sanjeevi 229
Part VII. Genetics
Predominance of the Group A Killer Ig Like Receptor Haplotypes in Korean
Patients with T1D. By Yongsoo Park, Heejin Choi, Hyewon Park,
Sukyung Park, Eun Kyung Yoo, Dukhee Kim,
and Carani B. Sanjeevi 240
Frequency of CTLA 4 Gene CT60 Polymorphism May Not Be Affected by
Vitamin D Receptor Gene Bsm I Polymorphism or HLA DR9 in
Autoimmune Related Type 1 Diabetes in the Japanese. By
Yasuhiko Kanazawa, Yoshiko Motohashi, Satoru Yamada,
yoichi olkawa, toshikatsu shigihara, yoshiaki okubo,
Taro Maruyama, and Akira Shimada 251
Genetic and Functional Evidence Supporting SUMO4 as a Type 1 Diabetes
Susceptibility Gene. By Cong Yi Wang, Robert Podolsky,
and Jin Xiong She 257
No Association of TLR2 and TLR4 Polymorphisms with Type I Diabetes
Mellitus in the Basque Population. By Izortze Santin, Jose Ramon Bilbao,
Guiomar Perez De Nanclares, Begona Calvo, and Luis Castano . 268
Association of SUMO4 M55V Polymorphism with Autoimmune Diabetes
in Latvian Patients. By Saikiran K. Sedimbi, Arun Shastry,
Yongsoo Park, Ingrida Rumba, and Carani B. Sanjeevi 273
A Second Component of HLA Linked Susceptibility to Type 1 Diabetes
Maps to Class I Region. By Yumiko Kawabata, Hiroshi Ikegami,
Tomomi Fujisawa, Shinsuke Noso, Katsuaki Asano,
yoshih1sa hlromine, and tosh1o ogihara 278
Molecular Scanning of the Gene for Programmed Cell Death 1 (PDCD 1) as a
Candidate for Type 1 Diabetes Susceptibility. By Yoshihisa Hiromine,
Hiroshi Ikegami, Tomomi Fujisawa, Yumiko Kawabata, Shinsuke Noso,
Kaori Yamaji, Katsuaki Asano, and Toshio Ogiharaa 285
Genetic Determinants of Type 1 Diabetes across Populations. By
Mohamed M. Jahromi and George S. Eisenbarth 289
TNFa e Microsatellite, HLA DRB1 and DQB1 Alleles and Haplotypes in
Brazilian Patients Presenting Recently Diagnosed Type 1 Diabetes
Mellitus. By Diane M. Rassi, Isabela J. Wastowski, Renata T. Simoes,
Sandra Rodrigues, Neife N.H.S. Deghaide, Celso T. Mendes Junior,
Aguinaldo L. Simoes, C.P. Soares, Geraldo A.S. Passos,
and Eduardo A. Donadi 300
Is HLA Class II Profile Relevant for the Study of Large Scale Differentially
Expressed Genes in Type 1 Diabetes Mellitus Patients? By
Diane M. Rassi, Cristina M. Junta, Ana L. Fachin,
Paula Sandrin Garcia, Stephano S. Mello, Ana P.M. Fernandes,
Neife N.H.S. Deghaide, Maria C. Foss Freitas, Milton C. Foss,
Elza T. Sakamoto Hojo, Geraldo A.S. Passos,
and Eduardo A. Donadi 305
Part VIII. Prediction and Prevention
Feasibility of a Type 1 Diabetes Primary Prevention Trial Using 2000 IU
Vitamin D3 in Infants from the General Population with Increased
HLA Associated Risk. By Brandy A. Wicklow
and Shayne P. Taback 310
Interleukin 10 Plasmid Construction and Delivery for the Prevention of Type 1
Diabetes. By Minhyung Lee, Hyewon Park, Jeehee Yoln, Eun Taex Oh,
KYUNGSOO KO, SUNGWAN KlM, AND YONGSOO PARK 313
TEDDY The Environmental Determinants of Diabetes in the Young. By
William A. Hagopian, Ake Lernmark, Marian J. Rewers,
Olli G. Simell, Jin Xiong She, Anettf G. Ziegler, Jeffrey P. Krisc her,
and Beena Akolkar 320
Protection from Type 1 Diabetes by Vitamin D Receptor Haplotypes. Si
Elizabeth Ramos Lopez, Thomas Jansen, Vytautas Ivaskeyktus.
Heinrr h Kahles, Christian Klepzig, Johannes Oldenburg,
and Klaus Badf.nhoop 327
Living Donor Islet Transplantation, the Alternative Approach to Overcome the
Obstacles Limiting Transplant. By Yasuhiro Iwanaga,
Shinichi Matslmoto, Teru Okitsu. Hiroflmi Noguchi. Hideo Nagata.
YUKIHIDE YONEKAWA, YUKHIRO YAMADA, KaZUHITO FUKUDA.
Katsushi Tsukiyama, and Koichi Tanaka 335
DiaPep277 Preserves Endogenous Insulin Production by Immunomodulation
in Type 1 Diabetes. By Dana Elias, Ann Avron, Merana Tamir,
AND ITAMAR RAZ 340
Cord Blood Islet Autoantibodies Are Related to Stress in the Mother during
Pregnancy. By Barbro Lernmark, Kristian Lynch, Ake Lernmark,
and The DiPiS Study Group 345
Is It Dietary Insulin? By Outi Vaarala 350
Probiotics for the Prevention of Beta Cell Autoimmunity in Children at
Genetic Risk of Type 1 Diabetes—the PRODIA Study. By
Martin Ljungberg, Riita Korpela, Jorma Ilonen,
Johnny Ludvigsson, and Outi Vaarala 360
Thiazolidinediones May Not Reduce Diabetes Incidence in Type 1 Diabetes. By
Toshikatsu Shigihara, Yoshiaki Okubo, Yasuhiko Kanazawa,
Yoichi Oikawa, and Akira Shimada 365
Mechanisms Mediating Anti CD3 Antibody Efficacy: Insights from
a Mathematical Model of Type 1 Diabetes. By Daniel L. Young,
Saroja Ramanujan, Huub T.C. Kreuwel, Chan Chung Whiting,
Kapil G. Gadkar, and Lisl K.M. Shoda 369
Why Diabetes Incidence Increases—A Unifying Theory. By Johnny
Ludvigsson 374
Overcoming the Challenges Now Limiting Islet Transplantation: A Sequential,
Integrated Approach. By Antonello Pileggi, Lorenzo Cobianchi,
Luca Inverardi, and Camillo Ricordi 383
Index of Contributors 399 |
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| illustrated | Not Illustrated |
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| spelling | Immunology of diabetes IV progress in our understanding ed. by Carani B. Sanjeevi ... Boston, Mass. Blackwell 2006 XV, 401 S. txt rdacontent n rdamedia nc rdacarrier Annals of the New York Academy of Sciences 1079 Diabetes Mellitus, Type 1 genetics Congresses Diabetes Mellitus, Type 1 immunology Congresses Diabetes Mellitus, Type 1 prevention & control Congresses Diabetes Immunological aspects Congresses Immunogenetics Congresses Autoaggressionskrankheit (DE-588)4003935-3 gnd rswk-swf Diabetes mellitus Typ 1 (DE-588)1194595685 gnd rswk-swf Pathogenese (DE-588)4115512-9 gnd rswk-swf Immunologie (DE-588)4026637-0 gnd rswk-swf (DE-588)1071861417 Konferenzschrift 2005 Awaji gnd-content Diabetes mellitus Typ 1 (DE-588)1194595685 s Immunologie (DE-588)4026637-0 s DE-604 Pathogenese (DE-588)4115512-9 s Autoaggressionskrankheit (DE-588)4003935-3 s b DE-604 Sanjeevi, Carani B. Sonstige (DE-588)124024548 oth Annals of the New York Academy of Sciences 1079 (DE-604)BV002532608 1079 HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=015432578&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Immunology of diabetes IV progress in our understanding Annals of the New York Academy of Sciences Diabetes Mellitus, Type 1 genetics Congresses Diabetes Mellitus, Type 1 immunology Congresses Diabetes Mellitus, Type 1 prevention & control Congresses Diabetes Immunological aspects Congresses Immunogenetics Congresses Autoaggressionskrankheit (DE-588)4003935-3 gnd Diabetes mellitus Typ 1 (DE-588)1194595685 gnd Pathogenese (DE-588)4115512-9 gnd Immunologie (DE-588)4026637-0 gnd |
| subject_GND | (DE-588)4003935-3 (DE-588)1194595685 (DE-588)4115512-9 (DE-588)4026637-0 (DE-588)1071861417 |
| title | Immunology of diabetes IV progress in our understanding |
| title_auth | Immunology of diabetes IV progress in our understanding |
| title_exact_search | Immunology of diabetes IV progress in our understanding |
| title_exact_search_txtP | Immunology of diabetes IV progress in our understanding |
| title_full | Immunology of diabetes IV progress in our understanding ed. by Carani B. Sanjeevi ... |
| title_fullStr | Immunology of diabetes IV progress in our understanding ed. by Carani B. Sanjeevi ... |
| title_full_unstemmed | Immunology of diabetes IV progress in our understanding ed. by Carani B. Sanjeevi ... |
| title_short | Immunology of diabetes IV |
| title_sort | immunology of diabetes iv progress in our understanding |
| title_sub | progress in our understanding |
| topic | Diabetes Mellitus, Type 1 genetics Congresses Diabetes Mellitus, Type 1 immunology Congresses Diabetes Mellitus, Type 1 prevention & control Congresses Diabetes Immunological aspects Congresses Immunogenetics Congresses Autoaggressionskrankheit (DE-588)4003935-3 gnd Diabetes mellitus Typ 1 (DE-588)1194595685 gnd Pathogenese (DE-588)4115512-9 gnd Immunologie (DE-588)4026637-0 gnd |
| topic_facet | Diabetes Mellitus, Type 1 genetics Congresses Diabetes Mellitus, Type 1 immunology Congresses Diabetes Mellitus, Type 1 prevention & control Congresses Diabetes Immunological aspects Congresses Immunogenetics Congresses Autoaggressionskrankheit Diabetes mellitus Typ 1 Pathogenese Immunologie Konferenzschrift 2005 Awaji |
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| volume_link | (DE-604)BV002532608 |
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