Cellular and molecular mechanisms of drugs of abuse and neurotoxicity: Cocaine, GHB, and substituted amphetamines
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New York, NY
New York Acad. of Sciences
2006
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Schriftenreihe: | Annals of the New York Academy of Sciences
1074 |
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Online-Zugang: | Inhaltsverzeichnis |
Beschreibung: | XVI, 676 S. Ill., graph. Darst. |
ISBN: | 1573316296 9781573316293 |
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490 | 1 | |a Annals of the New York Academy of Sciences |v 1074 | |
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650 | 4 | |a Cocaïne | |
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650 | 4 | |a Hydroxybutyrate de sodium | |
650 | 7 | |a Moleculaire biologie |2 gtt | |
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650 | 4 | |a Amphetamines |v Congresses | |
650 | 4 | |a Amphetamines |x adverse effects | |
650 | 4 | |a Amphetamines |x metabolism | |
650 | 4 | |a Cocaine |v Congresses | |
650 | 4 | |a Cocaine |x adverse effects | |
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650 | 4 | |a Gamma-hydroxybutyrate |v Congresses | |
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adam_text | ANNALS OF THE NEW YORK ACADEMY OF SCIENCES
Volume 1074
August 2006
CELLULAR AND MOLECULAR MECHANISMS OF
DRUGS OF ABUSE AND NEUROTOXICITY
Cocaine, GHB, and Substituted Amphetamines
Editors
Syed F. Ali and Francesco Fornai
This volume is the result of a meeting entitled Cellular and Molecular Mechanisms of
Drugs of Abuse and Neurotoxicity: Cocaine, GHB and Substituted Amphetamines,
and held on August 16 19, 2005 on Isola di San Servolo, Venice, Italy.
CONTENTS
Preface. By Syed F. Ali xv
Part I. Genes and Drugs of Abuse
Opposite Regulation of Cocaine Induced Intracellular Signaling and Gene
Expression by Dopamine Dl and D3 Receptors. By Jianhua Zhang and
Ming Xu 1
Serial Analysis of Gene Expression in the Rat Striatum Following
Methamphetamine Administration. By Ning Sheng Cai, Michael
T. McCoy, Bruce Ladenheim, Johnalyn Lyles, Syed F. Ali, and
Jean Lud Cadet 13
Dopamine Quinones Activate Microglia and Induce a Neurotoxic Gene
Expression Profile: Relationship to Methamphetamine Induced Nerve
Ending Damage. By Donald M. Kuhn, Dina M. Francescutti Verbeem,
and David M. Thomas 31
Gene Expression in the Brain from Fluoxetine Injected Mouse Using DNA
Microarray. By Yasuo Takahashi, Kazuo Washiyama, Toru Kobayashi,
and Shigenobu Hayashi 42
Short Term Effects of Adolescent Methylphenidate Exposure on Brain Striatal
Gene Expression and Sexual/Endocrine Parameters in Male Rats. By
Walter Adriani, Damiana Leo, Maria Guarino, Alessia Natoli,
Emma Di Consiglio, Giovanna De Angelis, Elsa Traina, Emanuela
Testai, Carla Perrone Capano, and Giovanni Laviola 52
Effects of L Carnitine Pretreatment in Methamphetamine and 3 Nitropropionic
Acid Induced Neurotoxicity. By Zbigniew K. Binienda, Beata D.
Przybyla, Bonnie L. Robinson, Nadia Salem, Ashraf Virmani,
Antonino Amato, and Syed F. Ali 74
Convergent Roles of a Synuclein, DA Metabolism, and the Ubiquitin
Proteasome System in Nigrostriatal Toxicity. By Francesco Fornai,
Gloria Lazzeri, Adolfo Bandettini Di Poggio, Paola Soldani,
Antonio De Blasi, Ferdinando Nicoletti, Stefano Ruggieri, and
Antonio Paparelli 84
Association Study of the Dihydropyrimidinase Related Protein 2 Gene and
Methamphetamine Psychosis. By H. Ujike, A. Sakai, K. Nakata,
Y. Tanaka, T. Kodaka, Y. Okahisa, M. Harano, T. Inada, M. Yamada,
T. Komiyama, T. Hori, Y. Sekine, N. Iwata, I. Sora, M. Iyo, N. Ozaki,
AND S. KURODA 90
Repeated Methamphetamine Administration Alters Expression of the NMDA
Receptor Channel e2 Subunit and Kinesins in the Mouse Brain. By Hideko
Yamamoto, Kazuhide Imai, Etsuko Kamegaya, Yukio Takamatsu,
Masashi Irago, Yoko Hagino, Sinya Kasai, Kiyo Shimada, Toshifumi
Yamamoto, Ichiro Sora, Hisashi Koga, and Kazutaka Ikeda 97
Genes and Gene Expression in the Brains of Human Alcoholics. By Peter R.
Dodd, S. Tracey Buckley, Allison L. Eckert, Philomena F. Foley,
and David J. Innes 104
Association Study of the Tumor Necrosis Factor a Gene and Its 1A Receptor
Gene with Methamphetamine Dependence. By A. Nomura, H. Ujike,
Y. Tanaka, M. Kishimoto, K. Otani, Y. Morita, A. Morio, M. Harano,
T. Inada, M. Yamada, T. Komiyama, T. Hori, Y. Sekine, N. Iwata,
I. Sora, M. Iyo, N. Ozaki, and S. Kuroda 116
Part II. Methamphetamine Neurotoxicity
Longitudinal Clinical Course Following Pharmacological Treatment of
Methamphetamine Psychosis Which Persists after Long Term
Abstinence. By Kazufumi Akiyama 125
Distinct Mechanisms Mediating Methamphetamine Induced Neuronal
Apoptosis and Dopamine Terminal Damage Share the Neuropeptide
Substance P in the Striatum of Mice. By Judy P.Q. Zhu, Wenjing Xu,
and Jesus A. Angulo 135
Effects of Methamphetamine on the Cerebellar Cortex: A Preliminary
Study. By Michela Ferrucci, Carla L. Busceti, Alessandra Falleni,
Filippo S. Giorgi, Stefano Ruggieri, and Francesco Fornai 149
Age Dependent Effects of Methamphetamine on VMAT 2. By Kristi S. Rau,
Jannine G. Truong, Diana G. Wilkins, Annette E. Fleckenstein,
and Glen R. Hanson 154
Methamphetamine, Morphine, and Their Combination: Acute Changes in
Striatal Dopaminergic Transmission Evaluated by Microdialysis in
Awake Rats. By Frederico C. Pereira, Elita Lourenco, Nuno Milhazes,
Teresa Morgadinho, Carlos F. Ribeiro, Syed F. Ali, and Tice R.
Macedo 160
In PC 12 Cells Neurotoxicity Induced by Methamphetamine Is Related to
Proteasome Inhibition. By Gloria Lazzeri, Paola Lenzi, Marco Gesi,
Michela Ferrucci, Federica Fulceri, Stefano Ruggieri,
Valeria Bruno, and Francesco Fornai 174
Human Immunodeficiency Virus 1 Protein Tat and Methamphetamine
Interactions. By Shaji Theodore, Stephanie Stolberg, Wayne A. Cass,
and William F. Maragos 178
Overexpression of a Synuclein following Methamphetamine: Is It Good or
Bad? By Giuseppe Mauceli, Carla 1. Busceti, Antonio Pellegrini,
Paola Soldani, Paola Lenzi, Antonio Paparelli, and Francesco
Fornai 191
Alterations in Blood Brain Barrier Function by Morphine and
Methamphetamine. By Hari Shanker Sharma and Syed F. Ali 198
Methamphetamine lnduced Selective Dopaminergic Neurotoxicity Is
Accompanied by an Increase in Striatal Nitrate in the Mouse. By Karen
L. Anderson and Yossef Itzhak . 225
Methamphetamine Induces Autophagy and Apoptosis in a Mesencephalic
Dopaminergic Neuronal Culture Model: Role of Cathepsin D in
Methamphetamine lnduced Apoptotic Cell Death. By Arthi
Kanthasamy, V Anantharam, Syed F. Ali, and A.G. Kanthasamy ... 234
Balance between Dopamine and Serotonin Release Modulates Behavioral
Effects of Amphetamine Type Drugs. By Richard B. Rothman
and Michael H. Baumann 245
Part III. METH: Oxidative Stress, Neurodegeneration, and Neuroprotection
Calcitriol Protects against the Dopamine and Serotonin Depleting Effects of
Neurotoxic Doses of Methamphetamine. By Wayne A. Cass, Michael P.
Smith, and Laura E. Peters 261
Protection by GDNF and Other Trophic Factors against the Dopamine
Depleting Effects of Neurotoxic Doses of Methamphetamine. By Wayne
A. Cass, Laura E. Peters, Michael E. Harned, and Kim B.
Seroogy 272
Estrogen, Testosterone, and Methamphetamine Toxicity. Bv Dean E. Dluzen
and Janet L. McDermott 282
Fluoxetine as a Potential Pharmacotherapy for Methamphetamine
Dependence: Studies in Mice. By Yukio Takamatsu, Hideko
Yamamoto, Yasukazu Ogai, Yoko Hagino, Athina Markou,
and Kazutaka Ikeda 295
Links between Nutrition, Drug Abuse, and the Metabolic Syndrome. By
ashraf vlrmani, zbigniew blnienda, syed ali, and franco
Gaetani 303
Part IV. METH and MPTP: Similarities and Differences
Inclusion Dynamics in PC 12 Is Comparable between Amphetamines and
MPTP. By Marco Gesi, Gloria Lazzeri, Michela Ferrucci,
Antonio Pellegrini, Paola Lenzi, Francesco Fornai, and Antonio
Paparelli 315
On the Effects of Psychostimulants, Antidepressants, and the
Antiparkinsonian Drug Levodopa on Dopamine Neurons. By Raffaella
Geracitano, Mauro Federici, Giorgio Bernardi, and Nicola B.
Mercuri 320
Effect of Oxidative Stress Induced by L Dopa on Endogenous Antioxidants
in PC 12 Cells. By Govind T. Vatassery, W. Ed Smith, and Hung T.
Quach 330
Dopamine Stimulation via Infusion in the Lateral Ventricle. By Francesca
Biagioni, Carla L. Busceti, Gemma Molinaro, Giuseppe Battaglia,
Filippo S. Giorgi, Stefano Ruggieri, and Francesco Fornai 337
Nigrostriatal Damage with 6 OHDA: Validation of Routinely Applied
Procedures. By Federica Fulceri, Francesca Biagioni, Paola Lenzi,
Alessandra Falleni, Marco Gesi, Stefano Ruggieri, and Francesco
Fornai 344
Calpain Activation in Apoptosis of Motoneurons in Cell Culture Models of
Experimental Parkinsonism. By Supriti Samantaray, Swapan K. Ray,
Syed F. Ali, and Naren L. Banik 349
Part V. MDMA and Other Substituted Amphetamines
MDMA and Seizures: A Dangerous Liaison? By Filippo S. Giorgi,
Gloria Lazzeri, Gianfranco Natale, Alfonso Iudice, Stefano
Ruggieri, Antonio Paparelli, Luigi Murri, and Francesco Fornai ... 357
Neural Effects of MDMA as Determined by Functional Magnetic Resonance
Imaging and Magnetic Resonance Spectroscopy in Awake Marmoset
Monkeys. By Jerrold S. Meyer, Matthew E. Brevard, Brian J. Piper,
Syed F. Ali, and Craig F. Ferris 365
MDMA Induces Caspase 3 Activation in the Limbic System but not in
Striatum. By Ilaria Tamburini, Fabio Blandini, Marco Gesi, Giada
Frenzilli, Marco Nigro, Mario Giusiani, Antonio Paparelli, and
Francesco Fornai 377
Part VI. Cocaine
Induction by Cocaine of the Serotonergic 5 HT3 Receptor in Rat
Cerebellum. By Marie Pierre Arpin Bott, Jean Bernard Dietrich,
Sylvie Dirrig Grosch, Dominique Aunis, and Jean Zwiller 382
Alpha Noradrenergic Receptors Modulate the Development and Expression of
Cocaine Sensitization. By Carlos A. Jimenez Rivera,
Monica Feliu Mojer, and Rafael Vazquez Torres 390
AMPA and NMDA Receptors in P2 Fractions of Cocaine and
Cocaine Prazosin Treated Rats. By J.G. Ortiz, S. Gonzalez Cabrera,
M. Rubio Davila, A. Tirado Costacamps, R. Vazquez Torres, N.
BERRioS CARTAGENA, W.I. SlLVA, AND C.A. JlMENEZ RlVERA 403
No Association between CART (Cocaine and Amphetamine Regulated
Transcript) Gene and Methamphetamine Dependence. By A. Morio,
H. Ujike, A. Nomura, Y. Tanaka, Y. Morita, K. Otani, M. Kjshimoto,
M. Harano, T. Inada, T. Komiyama, M. Yamada, Y. Sekjne, N. Iwata,
M. lYO, I. SORA, N. OZAKI, AND S. KURODA 411
Differential Effects of Donepezil on Methamphetamine and Cocaine
Dependencies. By Yukio Takamatsu, Yoshiharu Yamanishi,
Yoko Hagino, Hideko Yamamoto, and Kazutaka Ikeda 418
Hippocampal Synaptic Plasticity and Water Maze Learning in Cocaine
Self Administered Rats. By N. Del Olmo, A. Higuera Matas,
M. Miguens, C. Garci a Lecumberri, E. Borcel, J.M. Soli s,
and E. Ambrosio 427
Part VII. Heroine, Morphine, and Opiates
Comparison between Heroin and Heroin Cocaine Polyabusers: A
Psychopathological Study. By Adolfo Bandettini Di Poggio,
Francesco Fornai, Antonio Paparelli, Matteo Pacini,
Giulio Perugi, and Icro Maremmani 438
Persistent and Reversible Morphine Withdrawal Induced Morphological
Changes in the Nucleus Accumbens. By Marco Diana, Saturnino
Spiga, and Elio Acquas 446
Expression of NR1/NR2B jV Methyl D Aspartate Receptors Enhances Heroin
Toxicity in HEK293 Cells. By Antonio Domingues, Teresa Cunha
Oliveira, Mario L. N. Laco, Tice R.A. Macedo, Catarina R. Oliveira,
and A. Cristina Rego 458
Brain Blood Flow SPET Imaging in Heroin Abusers. By Maria Filomena
Botelho, Joao S. Relvas, Margarida Abrantes, Maria Joao Cunha,
Tiago R. Marques, Eugenia Rovira, Carlos A. Fontes Ribeiro, and
Tice Macedo 466
The Comet Assay as a Method of Assessment of Neurotoxicity: Usefulness
for Drugs of Abuse. By Giada Frenzilli, Vittoria Scarcelli,
Francesco Fornai, Antonio Paparelli, and Marco Nigro 478
A Potent Serotonin Modulating Compound AP 267 Attenuates Morphine
Withdrawal Induced Blood Brain Barrier Dysfunction in Rats. By Hari
S. Sharma, Torbjorn Lundstedt, Arne Boman, Per Lek,
Elisabeth Seifert, Lars Wiklund, and Syed F. Ali 482
Peri Response Pharmacokinetics of Remifentanil during a Self Administration
Session Indicates That Neither Blood nor Brain Levels Are Titrated. By
Jose A. Crespo, Leigh V Panlilio, Charles W. Schindler,
Katja Sturm, Alois Saria, and Gerald Zernig 497
Part VIII. Nicotine and Marijuana
Nicotine Alters Nicotinic Receptor Subunit Levels Differently in Developing
Mammalian Sympathetic Neurons. By Malathi Srivatsan,
Jonathan Treece, and Ezekiel E. Shotts 505
Discovery of the Presence and Functional Expression of Cannabinoid CB2
Receptors in Brain. By Emmanuel S. Onaivi, Hiroki Ishiguro, Jian Ping
Gong, Sejal Patel, Alex Perchuk, Paul A. Meozzi, Lester Myers,
Zoila Mora, Patricia Tagliaferro, Eileen Gardner, Alicia Brusco,
Babatunde E. Akinshola, Qing Rong Liu, Bruce Hope,
Shinya Iwasakj, Tadao Arinami, Lindsey Teasenfitz, and
George R. Uhl 514
Part IX. GHB
7 Hydroxybutyrate (GHB), 7 Butyrolactone (GBL), and 1,4 Butanediol
(1,4 BD) Reduce the Volume of Cerebral Infarction in Rodent Transient
Middle Cerebral Artery Occlusion. By Shankar Sadasivan,
Timothy J. Maher, and Lawrence S. Quang 537
Evaluation for the Withdrawal Syndrome from 7 Hydroxybutyric Acid (GHB),
7 Butyrolactone (GBL), and 1,4 Butanediol (1,4 BD) in Different
Rat Lines. By Lawrence S. Quang, Giancarlo Colombo,
Carla Lobina, Paola Maccioni, Alessandro Orru , Gian Luigi Gessa,
Timothy J. Maher, and Mauro A.M. Carai 545
7 Hydroxybutyrate (GHB) in Humans: Pharmacodynamics and
Pharmacokinetics. By Sergio Abanades, Magi Farre, Mireia Segura,
Simona Pichini, Diego Barral, Roberta Pacifici, Manuela Pellegrini,
Francina Fonseca, Klaus Langohr, and Rafael de la Torre 559
Part X. Perinatal Exposure and Postnatal Outcome:
Cocaine and Substituted Amphetamines
CNS Aspects of Prenatal Drug Exposure: Drugs of Abuse, Toxins, and
Corticosteroids. By Libor Veli sek 577
Effects of Prenatal Exposure to Methamphetamine on the Development of the
Rat Retina. By Pedro Melo, Lorena G. Rodrigues, M. Carolina Silva,
and Maria Amelia Tavares 590
Effects of Postnatal Exposure to Methamphetamine on the Development of
the Rat Retina. By Lorena G. Rodrigues, Pedro Melo, M. Carolina
Silva, and Maria Amelia Tavares 604
Prenatal Exposure to Cocaine and Enriched Environment: Effects on Social
Interactions. By Ana Magalhaes, Teresa Summavielle, Pedro Melo,
Rui Rosa, Maria Amelia Tavares, and Liliana de Sousa 620
Nitric Oxide and Oxidative Stress in the Brain of Rats Exposed In Utero to
Cocaine. By Valentina Bashkatova, Johann Meunier,
Anatoly Vanin, and Tangui Maurice 632
MDMA in Adolescent Male Rats: Decreased Serotonin in the Amygdala and
Behavioral Effects in the Elevated Plus Maze Test. By Raquel Faria,
Ana Magalhaes, Pedro R.R. Monteiro, Joana Gomes Da Silva,
Maria Amelia Tavares, and Teresa Summavielle 643
Morphological Evidence that Xenon Neuroprotects against AMvlethyl DL
Aspartic Acid Induced Damage in the Rat Arcuate Nucleus: A Time
Dependent Study. By Gianfranco Natale, Davide Cattano,
Antonio Abramo, Francesco Forfori, Federica Fulceri,
Francesco Fornai, Antonio Paparelli, and Francesco Giunta 650
Mechanism Based Approaches for the Reversal of Drug Neurobehavioral
Teratogenicity. By Joseph Yanai, Tamar L. Ben Shaanan,
Hana Haimovitch, Sophia Katz, and Meital Kazma 659
Index of Contributors 673
|
adam_txt |
ANNALS OF THE NEW YORK ACADEMY OF SCIENCES
Volume 1074
August 2006
CELLULAR AND MOLECULAR MECHANISMS OF
DRUGS OF ABUSE AND NEUROTOXICITY
Cocaine, GHB, and Substituted Amphetamines
Editors
Syed F. Ali and Francesco Fornai
This volume is the result of a meeting entitled Cellular and Molecular Mechanisms of
Drugs of Abuse and Neurotoxicity: Cocaine, GHB and Substituted Amphetamines,
and held on August 16 19, 2005 on Isola di San Servolo, Venice, Italy.
CONTENTS
Preface. By Syed F. Ali xv
Part I. Genes and Drugs of Abuse
Opposite Regulation of Cocaine Induced Intracellular Signaling and Gene
Expression by Dopamine Dl and D3 Receptors. By Jianhua Zhang and
Ming Xu 1
Serial Analysis of Gene Expression in the Rat Striatum Following
Methamphetamine Administration. By Ning Sheng Cai, Michael
T. McCoy, Bruce Ladenheim, Johnalyn Lyles, Syed F. Ali, and
Jean Lud Cadet 13
Dopamine Quinones Activate Microglia and Induce a Neurotoxic Gene
Expression Profile: Relationship to Methamphetamine Induced Nerve
Ending Damage. By Donald M. Kuhn, Dina M. Francescutti Verbeem,
and David M. Thomas 31
Gene Expression in the Brain from Fluoxetine Injected Mouse Using DNA
Microarray. By Yasuo Takahashi, Kazuo Washiyama, Toru Kobayashi,
and Shigenobu Hayashi 42
Short Term Effects of Adolescent Methylphenidate Exposure on Brain Striatal
Gene Expression and Sexual/Endocrine Parameters in Male Rats. By
Walter Adriani, Damiana Leo, Maria Guarino, Alessia Natoli,
Emma Di Consiglio, Giovanna De Angelis, Elsa Traina, Emanuela
Testai, Carla Perrone Capano, and Giovanni Laviola 52
Effects of L Carnitine Pretreatment in Methamphetamine and 3 Nitropropionic
Acid Induced Neurotoxicity. By Zbigniew K. Binienda, Beata D.
Przybyla, Bonnie L. Robinson, Nadia Salem, Ashraf Virmani,
Antonino Amato, and Syed F. Ali 74
Convergent Roles of a Synuclein, DA Metabolism, and the Ubiquitin
Proteasome System in Nigrostriatal Toxicity. By Francesco Fornai,
Gloria Lazzeri, Adolfo Bandettini Di Poggio, Paola Soldani,
Antonio De Blasi, Ferdinando Nicoletti, Stefano Ruggieri, and
Antonio Paparelli 84
Association Study of the Dihydropyrimidinase Related Protein 2 Gene and
Methamphetamine Psychosis. By H. Ujike, A. Sakai, K. Nakata,
Y. Tanaka, T. Kodaka, Y. Okahisa, M. Harano, T. Inada, M. Yamada,
T. Komiyama, T. Hori, Y. Sekine, N. Iwata, I. Sora, M. Iyo, N. Ozaki,
AND S. KURODA 90
Repeated Methamphetamine Administration Alters Expression of the NMDA
Receptor Channel e2 Subunit and Kinesins in the Mouse Brain. By Hideko
Yamamoto, Kazuhide Imai, Etsuko Kamegaya, Yukio Takamatsu,
Masashi Irago, Yoko Hagino, Sinya Kasai, Kiyo Shimada, Toshifumi
Yamamoto, Ichiro Sora, Hisashi Koga, and Kazutaka Ikeda 97
Genes and Gene Expression in the Brains of Human Alcoholics. By Peter R.
Dodd, S. Tracey Buckley, Allison L. Eckert, Philomena F. Foley,
and David J. Innes 104
Association Study of the Tumor Necrosis Factor a Gene and Its 1A Receptor
Gene with Methamphetamine Dependence. By A. Nomura, H. Ujike,
Y. Tanaka, M. Kishimoto, K. Otani, Y. Morita, A. Morio, M. Harano,
T. Inada, M. Yamada, T. Komiyama, T. Hori, Y. Sekine, N. Iwata,
I. Sora, M. Iyo, N. Ozaki, and S. Kuroda 116
Part II. Methamphetamine Neurotoxicity
Longitudinal Clinical Course Following Pharmacological Treatment of
Methamphetamine Psychosis Which Persists after Long Term
Abstinence. By Kazufumi Akiyama 125
Distinct Mechanisms Mediating Methamphetamine Induced Neuronal
Apoptosis and Dopamine Terminal Damage Share the Neuropeptide
Substance P in the Striatum of Mice. By Judy P.Q. Zhu, Wenjing Xu,
and Jesus A. Angulo 135
Effects of Methamphetamine on the Cerebellar Cortex: A Preliminary
Study. By Michela Ferrucci, Carla L. Busceti, Alessandra Falleni,
Filippo S. Giorgi, Stefano Ruggieri, and Francesco Fornai 149
Age Dependent Effects of Methamphetamine on VMAT 2. By Kristi S. Rau,
Jannine G. Truong, Diana G. Wilkins, Annette E. Fleckenstein,
and Glen R. Hanson 154
Methamphetamine, Morphine, and Their Combination: Acute Changes in
Striatal Dopaminergic Transmission Evaluated by Microdialysis in
Awake Rats. By Frederico C. Pereira, Elita Lourenco, Nuno Milhazes,
Teresa Morgadinho, Carlos F. Ribeiro, Syed F. Ali, and Tice R.
Macedo 160
In PC 12 Cells Neurotoxicity Induced by Methamphetamine Is Related to
Proteasome Inhibition. By Gloria Lazzeri, Paola Lenzi, Marco Gesi,
Michela Ferrucci, Federica Fulceri, Stefano Ruggieri,
Valeria Bruno, and Francesco Fornai 174
Human Immunodeficiency Virus 1 Protein Tat and Methamphetamine
Interactions. By Shaji Theodore, Stephanie Stolberg, Wayne A. Cass,
and William F. Maragos 178
Overexpression of a Synuclein following Methamphetamine: Is It Good or
Bad? By Giuseppe Mauceli, Carla 1. Busceti, Antonio Pellegrini,
Paola Soldani, Paola Lenzi, Antonio Paparelli, and Francesco
Fornai 191
Alterations in Blood Brain Barrier Function by Morphine and
Methamphetamine. By Hari Shanker Sharma and Syed F. Ali 198
Methamphetamine lnduced Selective Dopaminergic Neurotoxicity Is
Accompanied by an Increase in Striatal Nitrate in the Mouse. By Karen
L. Anderson and Yossef Itzhak ". 225
Methamphetamine Induces Autophagy and Apoptosis in a Mesencephalic
Dopaminergic Neuronal Culture Model: Role of Cathepsin D in
Methamphetamine lnduced Apoptotic Cell Death. By Arthi
Kanthasamy, V Anantharam, Syed F. Ali, and A.G. Kanthasamy . 234
Balance between Dopamine and Serotonin Release Modulates Behavioral
Effects of Amphetamine Type Drugs. By Richard B. Rothman
and Michael H. Baumann 245
Part III. METH: Oxidative Stress, Neurodegeneration, and Neuroprotection
Calcitriol Protects against the Dopamine and Serotonin Depleting Effects of
Neurotoxic Doses of Methamphetamine. By Wayne A. Cass, Michael P.
Smith, and Laura E. Peters 261
Protection by GDNF and Other Trophic Factors against the Dopamine
Depleting Effects of Neurotoxic Doses of Methamphetamine. By Wayne
A. Cass, Laura E. Peters, Michael E. Harned, and Kim B.
Seroogy 272
Estrogen, Testosterone, and Methamphetamine Toxicity. Bv Dean E. Dluzen
and Janet L. McDermott 282
Fluoxetine as a Potential Pharmacotherapy for Methamphetamine
Dependence: Studies in Mice. By Yukio Takamatsu, Hideko
Yamamoto, Yasukazu Ogai, Yoko Hagino, Athina Markou,
and Kazutaka Ikeda 295
Links between Nutrition, Drug Abuse, and the Metabolic Syndrome. By
ashraf vlrmani, zbigniew blnienda, syed ali, and franco
Gaetani 303
Part IV. METH and MPTP: Similarities and Differences
Inclusion Dynamics in PC 12 Is Comparable between Amphetamines and
MPTP. By Marco Gesi, Gloria Lazzeri, Michela Ferrucci,
Antonio Pellegrini, Paola Lenzi, Francesco Fornai, and Antonio
Paparelli 315
On the Effects of Psychostimulants, Antidepressants, and the
Antiparkinsonian Drug Levodopa on Dopamine Neurons. By Raffaella
Geracitano, Mauro Federici, Giorgio Bernardi, and Nicola B.
Mercuri 320
Effect of Oxidative Stress Induced by L Dopa on Endogenous Antioxidants
in PC 12 Cells. By Govind T. Vatassery, W. Ed Smith, and Hung T.
Quach 330
Dopamine Stimulation via Infusion in the Lateral Ventricle. By Francesca
Biagioni, Carla L. Busceti, Gemma Molinaro, Giuseppe Battaglia,
Filippo S. Giorgi, Stefano Ruggieri, and Francesco Fornai 337
Nigrostriatal Damage with 6 OHDA: Validation of Routinely Applied
Procedures. By Federica Fulceri, Francesca Biagioni, Paola Lenzi,
Alessandra Falleni, Marco Gesi, Stefano Ruggieri, and Francesco
Fornai 344
Calpain Activation in Apoptosis of Motoneurons in Cell Culture Models of
Experimental Parkinsonism. By Supriti Samantaray, Swapan K. Ray,
Syed F. Ali, and Naren L. Banik 349
Part V. MDMA and Other Substituted Amphetamines
MDMA and Seizures: A Dangerous Liaison? By Filippo S. Giorgi,
Gloria Lazzeri, Gianfranco Natale, Alfonso Iudice, Stefano
Ruggieri, Antonio Paparelli, Luigi Murri, and Francesco Fornai . 357
Neural Effects of MDMA as Determined by Functional Magnetic Resonance
Imaging and Magnetic Resonance Spectroscopy in Awake Marmoset
Monkeys. By Jerrold S. Meyer, Matthew E. Brevard, Brian J. Piper,
Syed F. Ali, and Craig F. Ferris 365
MDMA Induces Caspase 3 Activation in the Limbic System but not in
Striatum. By Ilaria Tamburini, Fabio Blandini, Marco Gesi, Giada
Frenzilli, Marco Nigro, Mario Giusiani, Antonio Paparelli, and
Francesco Fornai 377
Part VI. Cocaine
Induction by Cocaine of the Serotonergic 5 HT3 Receptor in Rat
Cerebellum. By Marie Pierre Arpin Bott, Jean Bernard Dietrich,
Sylvie Dirrig Grosch, Dominique Aunis, and Jean Zwiller 382
Alpha Noradrenergic Receptors Modulate the Development and Expression of
Cocaine Sensitization. By Carlos A. Jimenez Rivera,
Monica Feliu Mojer, and Rafael Vazquez Torres 390
AMPA and NMDA Receptors in P2 Fractions of Cocaine and
Cocaine Prazosin Treated Rats. By J.G. Ortiz, S. Gonzalez Cabrera,
M. Rubio Davila, A. Tirado Costacamps, R. Vazquez Torres, N.
BERRioS CARTAGENA, W.I. SlLVA, AND C.A. JlMENEZ RlVERA 403
No Association between CART (Cocaine and Amphetamine Regulated
Transcript) Gene and Methamphetamine Dependence. By A. Morio,
H. Ujike, A. Nomura, Y. Tanaka, Y. Morita, K. Otani, M. Kjshimoto,
M. Harano, T. Inada, T. Komiyama, M. Yamada, Y. Sekjne, N. Iwata,
M. lYO, I. SORA, N. OZAKI, AND S. KURODA 411
Differential Effects of Donepezil on Methamphetamine and Cocaine
Dependencies. By Yukio Takamatsu, Yoshiharu Yamanishi,
Yoko Hagino, Hideko Yamamoto, and Kazutaka Ikeda 418
Hippocampal Synaptic Plasticity and Water Maze Learning in Cocaine
Self Administered Rats. By N. Del Olmo, A. Higuera Matas,
M. Miguens, C. Garci'a Lecumberri, E. Borcel, J.M. Soli's,
and E. Ambrosio 427
Part VII. Heroine, Morphine, and Opiates
Comparison between Heroin and Heroin Cocaine Polyabusers: A
Psychopathological Study. By Adolfo Bandettini Di Poggio,
Francesco Fornai, Antonio Paparelli, Matteo Pacini,
Giulio Perugi, and Icro Maremmani 438
Persistent and Reversible Morphine Withdrawal Induced Morphological
Changes in the Nucleus Accumbens. By Marco Diana, Saturnino
Spiga, and Elio Acquas 446
Expression of NR1/NR2B jV Methyl D Aspartate Receptors Enhances Heroin
Toxicity in HEK293 Cells. By Antonio Domingues, Teresa Cunha
Oliveira, Mario L. N. Laco, Tice R.A. Macedo, Catarina R. Oliveira,
and A. Cristina Rego 458
Brain Blood Flow SPET Imaging in Heroin Abusers. By Maria Filomena
Botelho, Joao S. Relvas, Margarida Abrantes, Maria Joao Cunha,
Tiago R. Marques, Eugenia Rovira, Carlos A. Fontes Ribeiro, and
Tice Macedo 466
The Comet Assay as a Method of Assessment of Neurotoxicity: Usefulness
for Drugs of Abuse. By Giada Frenzilli, Vittoria Scarcelli,
Francesco Fornai, Antonio Paparelli, and Marco Nigro 478
A Potent Serotonin Modulating Compound AP 267 Attenuates Morphine
Withdrawal Induced Blood Brain Barrier Dysfunction in Rats. By Hari
S. Sharma, Torbjorn Lundstedt, Arne Boman, Per Lek,
Elisabeth Seifert, Lars Wiklund, and Syed F. Ali 482
Peri Response Pharmacokinetics of Remifentanil during a Self Administration
Session Indicates That Neither Blood nor Brain Levels Are Titrated. By
Jose A. Crespo, Leigh V Panlilio, Charles W. Schindler,
Katja Sturm, Alois Saria, and Gerald Zernig 497
Part VIII. Nicotine and Marijuana
Nicotine Alters Nicotinic Receptor Subunit Levels Differently in Developing
Mammalian Sympathetic Neurons. By Malathi Srivatsan,
Jonathan Treece, and Ezekiel E. Shotts 505
Discovery of the Presence and Functional Expression of Cannabinoid CB2
Receptors in Brain. By Emmanuel S. Onaivi, Hiroki Ishiguro, Jian Ping
Gong, Sejal Patel, Alex Perchuk, Paul A. Meozzi, Lester Myers,
Zoila Mora, Patricia Tagliaferro, Eileen Gardner, Alicia Brusco,
Babatunde E. Akinshola, Qing Rong Liu, Bruce Hope,
Shinya Iwasakj, Tadao Arinami, Lindsey Teasenfitz, and
George R. Uhl 514
Part IX. GHB
7 Hydroxybutyrate (GHB), 7 Butyrolactone (GBL), and 1,4 Butanediol
(1,4 BD) Reduce the Volume of Cerebral Infarction in Rodent Transient
Middle Cerebral Artery Occlusion. By Shankar Sadasivan,
Timothy J. Maher, and Lawrence S. Quang 537
Evaluation for the Withdrawal Syndrome from 7 Hydroxybutyric Acid (GHB),
7 Butyrolactone (GBL), and 1,4 Butanediol (1,4 BD) in Different
Rat Lines. By Lawrence S. Quang, Giancarlo Colombo,
Carla Lobina, Paola Maccioni, Alessandro Orru", Gian Luigi Gessa,
Timothy J. Maher, and Mauro A.M. Carai 545
7 Hydroxybutyrate (GHB) in Humans: Pharmacodynamics and
Pharmacokinetics. By Sergio Abanades, Magi Farre, Mireia Segura,
Simona Pichini, Diego Barral, Roberta Pacifici, Manuela Pellegrini,
Francina Fonseca, Klaus Langohr, and Rafael de la Torre 559
Part X. Perinatal Exposure and Postnatal Outcome:
Cocaine and Substituted Amphetamines
CNS Aspects of Prenatal Drug Exposure: Drugs of Abuse, Toxins, and
Corticosteroids. By Libor Veli'sek 577
Effects of Prenatal Exposure to Methamphetamine on the Development of the
Rat Retina. By Pedro Melo, Lorena G. Rodrigues, M. Carolina Silva,
and Maria Amelia Tavares 590
Effects of Postnatal Exposure to Methamphetamine on the Development of
the Rat Retina. By Lorena G. Rodrigues, Pedro Melo, M. Carolina
Silva, and Maria Amelia Tavares 604
Prenatal Exposure to Cocaine and Enriched Environment: Effects on Social
Interactions. By Ana Magalhaes, Teresa Summavielle, Pedro Melo,
Rui Rosa, Maria Amelia Tavares, and Liliana de Sousa 620
Nitric Oxide and Oxidative Stress in the Brain of Rats Exposed In Utero to
Cocaine. By Valentina Bashkatova, Johann Meunier,
Anatoly Vanin, and Tangui Maurice 632
MDMA in Adolescent Male Rats: Decreased Serotonin in the Amygdala and
Behavioral Effects in the Elevated Plus Maze Test. By Raquel Faria,
Ana Magalhaes, Pedro R.R. Monteiro, Joana Gomes Da Silva,
Maria Amelia Tavares, and Teresa Summavielle 643
Morphological Evidence that Xenon Neuroprotects against AMvlethyl DL
Aspartic Acid Induced Damage in the Rat Arcuate Nucleus: A Time
Dependent Study. By Gianfranco Natale, Davide Cattano,
Antonio Abramo, Francesco Forfori, Federica Fulceri,
Francesco Fornai, Antonio Paparelli, and Francesco Giunta 650
Mechanism Based Approaches for the Reversal of Drug Neurobehavioral
Teratogenicity. By Joseph Yanai, Tamar L. Ben Shaanan,
Hana Haimovitch, Sophia Katz, and Meital Kazma 659
Index of Contributors 673 |
any_adam_object | 1 |
any_adam_object_boolean | 1 |
building | Verbundindex |
bvnumber | BV021821797 |
callnumber-first | Q - Science |
callnumber-label | Q11 |
callnumber-raw | Q11 RM316 |
callnumber-search | Q11 RM316 |
callnumber-sort | Q 211 |
callnumber-subject | Q - General Science |
ctrlnum | (OCoLC)70119697 (DE-599)BVBBV021821797 |
dewey-full | 615/.78 |
dewey-hundreds | 600 - Technology (Applied sciences) |
dewey-ones | 615 - Pharmacology and therapeutics |
dewey-raw | 615/.78 |
dewey-search | 615/.78 |
dewey-sort | 3615 278 |
dewey-tens | 610 - Medicine and health |
discipline | Medizin |
discipline_str_mv | Medizin |
format | Book |
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genre_facet | Konferenzschrift 2005 Venedig Electronic books |
id | DE-604.BV021821797 |
illustrated | Illustrated |
index_date | 2024-07-02T15:54:29Z |
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institution | BVB |
isbn | 1573316296 9781573316293 |
language | English |
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physical | XVI, 676 S. Ill., graph. Darst. |
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spelling | Cellular and molecular mechanisms of drugs of abuse and neurotoxicity Cocaine, GHB, and substituted amphetamines ed. by Syed F. Ali ... New York, NY New York Acad. of Sciences 2006 XVI, 676 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Annals of the New York Academy of Sciences 1074 Amphétamines Cocaïne Drogues illicites Drugs gtt Hydroxybutyrate de sodium Moleculaire biologie gtt Neurotoxicologie Verslaving gtt Amphetamines Congresses Amphetamines adverse effects Amphetamines metabolism Cocaine Congresses Cocaine adverse effects Cocaine metabolism Drugs of abuse Congresses Gamma-hydroxybutyrate Congresses Neurotoxicity Syndromes Neurotoxicology Congresses Street Drugs pharmacokinetics Neurotoxikologie (DE-588)4457830-1 gnd rswk-swf Rauschgift (DE-588)4048610-2 gnd rswk-swf (DE-588)1071861417 Konferenzschrift 2005 Venedig gnd-content Electronic books Rauschgift (DE-588)4048610-2 s Neurotoxikologie (DE-588)4457830-1 s DE-604 Ali, Syed F. Sonstige oth Annals of the New York Academy of Sciences 1074 (DE-604)BV002532608 1074 HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=015033929&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
spellingShingle | Cellular and molecular mechanisms of drugs of abuse and neurotoxicity Cocaine, GHB, and substituted amphetamines Annals of the New York Academy of Sciences Amphétamines Cocaïne Drogues illicites Drugs gtt Hydroxybutyrate de sodium Moleculaire biologie gtt Neurotoxicologie Verslaving gtt Amphetamines Congresses Amphetamines adverse effects Amphetamines metabolism Cocaine Congresses Cocaine adverse effects Cocaine metabolism Drugs of abuse Congresses Gamma-hydroxybutyrate Congresses Neurotoxicity Syndromes Neurotoxicology Congresses Street Drugs pharmacokinetics Neurotoxikologie (DE-588)4457830-1 gnd Rauschgift (DE-588)4048610-2 gnd |
subject_GND | (DE-588)4457830-1 (DE-588)4048610-2 (DE-588)1071861417 |
title | Cellular and molecular mechanisms of drugs of abuse and neurotoxicity Cocaine, GHB, and substituted amphetamines |
title_auth | Cellular and molecular mechanisms of drugs of abuse and neurotoxicity Cocaine, GHB, and substituted amphetamines |
title_exact_search | Cellular and molecular mechanisms of drugs of abuse and neurotoxicity Cocaine, GHB, and substituted amphetamines |
title_exact_search_txtP | Cellular and molecular mechanisms of drugs of abuse and neurotoxicity Cocaine, GHB, and substituted amphetamines |
title_full | Cellular and molecular mechanisms of drugs of abuse and neurotoxicity Cocaine, GHB, and substituted amphetamines ed. by Syed F. Ali ... |
title_fullStr | Cellular and molecular mechanisms of drugs of abuse and neurotoxicity Cocaine, GHB, and substituted amphetamines ed. by Syed F. Ali ... |
title_full_unstemmed | Cellular and molecular mechanisms of drugs of abuse and neurotoxicity Cocaine, GHB, and substituted amphetamines ed. by Syed F. Ali ... |
title_short | Cellular and molecular mechanisms of drugs of abuse and neurotoxicity |
title_sort | cellular and molecular mechanisms of drugs of abuse and neurotoxicity cocaine ghb and substituted amphetamines |
title_sub | Cocaine, GHB, and substituted amphetamines |
topic | Amphétamines Cocaïne Drogues illicites Drugs gtt Hydroxybutyrate de sodium Moleculaire biologie gtt Neurotoxicologie Verslaving gtt Amphetamines Congresses Amphetamines adverse effects Amphetamines metabolism Cocaine Congresses Cocaine adverse effects Cocaine metabolism Drugs of abuse Congresses Gamma-hydroxybutyrate Congresses Neurotoxicity Syndromes Neurotoxicology Congresses Street Drugs pharmacokinetics Neurotoxikologie (DE-588)4457830-1 gnd Rauschgift (DE-588)4048610-2 gnd |
topic_facet | Amphétamines Cocaïne Drogues illicites Drugs Hydroxybutyrate de sodium Moleculaire biologie Neurotoxicologie Verslaving Amphetamines Congresses Amphetamines adverse effects Amphetamines metabolism Cocaine Congresses Cocaine adverse effects Cocaine metabolism Drugs of abuse Congresses Gamma-hydroxybutyrate Congresses Neurotoxicity Syndromes Neurotoxicology Congresses Street Drugs pharmacokinetics Neurotoxikologie Rauschgift Konferenzschrift 2005 Venedig Electronic books |
url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=015033929&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
volume_link | (DE-604)BV002532608 |
work_keys_str_mv | AT alisyedf cellularandmolecularmechanismsofdrugsofabuseandneurotoxicitycocaineghbandsubstitutedamphetamines |