Systems biology:
Gespeichert in:
Format: | Buch |
---|---|
Sprache: | English |
Veröffentlicht: |
Dordrecht
Springer
2007
|
Ausgabe: | 1. ed. |
Schriftenreihe: | Cell Engineering
5 |
Schlagworte: | |
Online-Zugang: | Inhaltsverzeichnis |
ISBN: | 1402052510 |
Internformat
MARC
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Datensatz im Suchindex
_version_ | 1804135628071239680 |
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adam_text | Systems Biology
Philosophical Foundations
Edited by
Fred C Boogerd
and
Frank J Bruggeman
Department of Molecular Cell Physiology
Faculty of Earth and Life Sciences
Vrije Universiteit, Amsterdam, The Netherlands
Jan-Hendrik S Hofmeyr
Department of Biochemistry, Faculty of Science
University of Stellenbosch, Stellenbosch, South Africa
Hans V Westerhoff
Department of Molecular Cell Physiology
Faculty of Earth and Life Sciences
Vrije Universiteit, Amsterdam, The Netherlands
and
Manchester Centre for Integrative Systems Biology
The University of Manchester, Manchester, United Kingdom
ELSEVIER
Amsterdam • Boston • Heidelberg • London • New York • Oxford
Paris • San Diego • San Francisco • Singapore • Sydney • Tokyo
Contents
List of Contributors vii
Contributor Biographies ix
Preface xvii
Section I Introduction ~ 1
1 Towards philosophical foundations of Systems Biology: introduction 3
F C Boogerd, F J Bruggeman, J -H S Hofmeyr and H V Westerhoff
Section II Research programs of Systems Biology 21
2 The methodologies of systems biology 23
H V Westerhoff and D B Kell
3 Methodology is Philosophy 71
R G Shulinan
4 How can we understand metabolism? 87
DA Fell
5 On building reliable pictures with unreliable data: An evolutionary
and developmental coda for the new systems biology? 103
W C Wiinsatt
Section III Theory and models 121
6 Mechanism and mechanical explanation in systems biology 123
R C Richardson and A Stephan
7 Theories, models, and equations in systems biology 145
K F Schaffner
8 All models are wrong some more than others 163
O Wolkenhauer and M Ullah
9 Data without models merging with models without data 181
U Krohs and W Callebaut
vi Contents
Section IV Organization in biological systems 215
10 The biochemical factory that autonomously fabricates itself:
A systems biological view of the living cell 217
J -H S Hofmeyr
11 A systemic approach to the origin of biological organization 243
A Moreno
12 Biological mechanisms: organized to maintain autonomy 269
W Bechtel
13 The disappearance of function from self-organizing systems 303
E F Keller
Section V Conclusion 319
14 Afterthoughts as foundations for systems biology 321
F C Boogerd, F J Bruggeman, J -H S Hofmeyr
and H V Westerhoff
Subject Index 337
|
adam_txt |
Systems Biology
Philosophical Foundations
Edited by
Fred C Boogerd
and
Frank J Bruggeman
Department of Molecular Cell Physiology
Faculty of Earth and Life Sciences
Vrije Universiteit, Amsterdam, The Netherlands
Jan-Hendrik S Hofmeyr
Department of Biochemistry, Faculty of Science
University of Stellenbosch, Stellenbosch, South Africa
Hans V Westerhoff
Department of Molecular Cell Physiology
Faculty of Earth and Life Sciences
Vrije Universiteit, Amsterdam, The Netherlands
and
Manchester Centre for Integrative Systems Biology
The University of Manchester, Manchester, United Kingdom
ELSEVIER
Amsterdam • Boston • Heidelberg • London • New York • Oxford
Paris • San Diego • San Francisco • Singapore • Sydney • Tokyo
Contents
List of Contributors vii
Contributor Biographies ix
Preface xvii
Section I Introduction ~ 1
1 Towards philosophical foundations of Systems Biology: introduction 3
F C Boogerd, F J Bruggeman, J -H S Hofmeyr and H V Westerhoff
Section II Research programs of Systems Biology 21
2 The methodologies of systems biology 23
H V Westerhoff and D B Kell
3 Methodology is Philosophy 71
R G Shulinan
4 How can we understand metabolism? 87
DA Fell
5 On building reliable pictures with unreliable data: An evolutionary
and developmental coda for the new systems biology? 103
W C Wiinsatt
Section III Theory and models 121
6 Mechanism and mechanical explanation in systems biology 123
R C Richardson and A Stephan
7 Theories, models, and equations in systems biology 145
K F Schaffner
8 All models are wrong some more than others 163
O Wolkenhauer and M Ullah
9 Data without models merging with models without data 181
U Krohs and W Callebaut
vi Contents
Section IV Organization in biological systems 215
10 The biochemical factory that autonomously fabricates itself:
A systems biological view of the living cell 217
J -H S Hofmeyr
11 A systemic approach to the origin of biological organization 243
A Moreno
12 Biological mechanisms: organized to maintain autonomy 269
W Bechtel
13 The disappearance of function from'self-organizing systems' 303
E F Keller
Section V Conclusion 319
14 Afterthoughts as foundations for systems biology 321
F C Boogerd, F J Bruggeman, J -H S Hofmeyr
and H V Westerhoff
Subject Index 337 |
any_adam_object | 1 |
any_adam_object_boolean | 1 |
building | Verbundindex |
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ctrlnum | (OCoLC)77482079 (DE-599)BVBBV021764138 |
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dewey-hundreds | 500 - Natural sciences and mathematics |
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dewey-search | 571.6 |
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discipline | Biologie |
discipline_str_mv | Biologie |
edition | 1. ed. |
format | Book |
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isbn | 1402052510 |
language | English |
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publishDate | 2007 |
publishDateSearch | 2007 |
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publisher | Springer |
record_format | marc |
series | Cell Engineering |
series2 | Cell Engineering |
spelling | Systems biology Hrsg. Mohamed Al- Rubeai ... 1. ed. Dordrecht Springer 2007 txt rdacontent n rdamedia nc rdacarrier Cell Engineering 5 Biological systems Cell physiology Systems biology Biochemie (DE-588)4006777-4 gnd rswk-swf Systembiologie (DE-588)4809615-5 gnd rswk-swf 1\p (DE-588)4143413-4 Aufsatzsammlung gnd-content Biochemie (DE-588)4006777-4 s Systembiologie (DE-588)4809615-5 s 2\p DE-604 Al-Rubeai, Mohamed Sonstige oth Cell Engineering 5 (DE-604)BV013305149 5 HEBIS Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=014977164&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk 2\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
spellingShingle | Systems biology Cell Engineering Biological systems Cell physiology Systems biology Biochemie (DE-588)4006777-4 gnd Systembiologie (DE-588)4809615-5 gnd |
subject_GND | (DE-588)4006777-4 (DE-588)4809615-5 (DE-588)4143413-4 |
title | Systems biology |
title_auth | Systems biology |
title_exact_search | Systems biology |
title_exact_search_txtP | Systems biology |
title_full | Systems biology Hrsg. Mohamed Al- Rubeai ... |
title_fullStr | Systems biology Hrsg. Mohamed Al- Rubeai ... |
title_full_unstemmed | Systems biology Hrsg. Mohamed Al- Rubeai ... |
title_short | Systems biology |
title_sort | systems biology |
topic | Biological systems Cell physiology Systems biology Biochemie (DE-588)4006777-4 gnd Systembiologie (DE-588)4809615-5 gnd |
topic_facet | Biological systems Cell physiology Systems biology Biochemie Systembiologie Aufsatzsammlung |
url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=014977164&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
volume_link | (DE-604)BV013305149 |
work_keys_str_mv | AT alrubeaimohamed systemsbiology |