Organic synthetic methods:
Gespeichert in:
| 1. Verfasser: | |
|---|---|
| Format: | Buch |
| Sprache: | English |
| Veröffentlicht: |
Cambridge, UK
Royal Soc. of Chemistry
2002
|
| Schriftenreihe: | Tutorial chemistry texts
12 |
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | VII, 175 S. Ill. |
| ISBN: | 0854046828 |
Internformat
MARC
| LEADER | 00000nam a2200000 cb4500 | ||
|---|---|---|---|
| 001 | BV021692181 | ||
| 003 | DE-604 | ||
| 005 | 00000000000000.0 | ||
| 007 | t | ||
| 008 | 060810s2002 a||| |||| 00||| eng d | ||
| 020 | |a 0854046828 |9 0-85404-682-8 | ||
| 035 | |a (OCoLC)248805036 | ||
| 035 | |a (DE-599)BVBBV021692181 | ||
| 040 | |a DE-604 |b ger |e rakwb | ||
| 041 | 0 | |a eng | |
| 049 | |a DE-19 |a DE-634 | ||
| 050 | 0 | |a QD262 | |
| 082 | 0 | |a 547.2 | |
| 084 | |a VK 5501 |0 (DE-625)147401:254 |2 rvk | ||
| 100 | 1 | |a Hanson, James R. |e Verfasser |4 aut | |
| 245 | 1 | 0 | |a Organic synthetic methods |c James R. Hanson |
| 264 | 1 | |a Cambridge, UK |b Royal Soc. of Chemistry |c 2002 | |
| 300 | |a VII, 175 S. |b Ill. | ||
| 336 | |b txt |2 rdacontent | ||
| 337 | |b n |2 rdamedia | ||
| 338 | |b nc |2 rdacarrier | ||
| 490 | 1 | |a Tutorial chemistry texts |v 12 | |
| 650 | 4 | |a Organic compounds |x Synthesis | |
| 650 | 4 | |a Organic compounds |x Synthesis |v Problems, exercises, etc | |
| 650 | 0 | 7 | |a Organische Synthese |0 (DE-588)4075695-6 |2 gnd |9 rswk-swf |
| 655 | 7 | |0 (DE-588)4123623-3 |a Lehrbuch |2 gnd-content | |
| 689 | 0 | 0 | |a Organische Synthese |0 (DE-588)4075695-6 |D s |
| 689 | 0 | |5 DE-604 | |
| 830 | 0 | |a Tutorial chemistry texts |v 12 |w (DE-604)BV035419963 |9 12 | |
| 856 | 4 | 2 | |m HBZ Datenaustausch |q application/pdf |u http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=014906236&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |3 Inhaltsverzeichnis |
| 999 | |a oai:aleph.bib-bvb.de:BVB01-014906236 | ||
Datensatz im Suchindex
| _version_ | 1804135518974246912 |
|---|---|
| adam_text | Contents
1 Introduction 1
1.1 Synthetic Strategies 1
1.2 Steric Factors 3
1.3 Criteria for Evaluating Synthetic Routes 3
1.4 Some Synthetic Terms 6
1.5 Learning to Apply Synthetic Methods 6
2 Organometallic and Ylide Methods of 9
Carbon-Carbon Bond Formation
2.1 Introduction 9
2.2 Reactions of Organometallic Compounds 11
2.3 Acetylides and Nitriles 20
2.4 Ylide Reactions 22
2.5 Silicon and Boron in C-C Bond Formation 26
3 Carbonyl Activation and Enolate Chemistry 32
in Carbon-Carbon Bond Formation
3.1 Introduction 32
3.2 Alkylation Reactions 36
3.3 Enolate Anions in Carbonyl Addition Reactions 39
3.4 The Stereochemistry of Condensation Reactions 48
4 Carbocations in Synthesis 54
4.1 Introduction 54
4.2 Alkyl Carbocations: the Friedel-Crafts Alkylation 55
4.3 Carbocations Derived from Aldehydes and Ketones 56
4.4 Acylium Carbocations: the Friedel-Crafts Acylation 57
4.5 Acid-catalysed Rearrangement Reactions 58
5 Free Radical and Pericyclic Reactions in the 64
Formation of Carbon-Carbon Bonds
5.1 Carbon Radical Reactions 64
5.2 Radical Addition Reactions 68
5.3 Carbenes 69
5.4 Alkene Metathesis 70
•5.5 The Diels-Alder Reaction 71
5.6 The Ene Reaction 73
5.7 The Cope and Claisen Rearrangements 73
6 Methods of Making Carbon-Nitrogen Bonds 78
6.1 Introduction 78
6.2 Electrophilic Methods of Making C-N Bonds 79
6.3 Nucleophilic Methods of Making C-N Bonds 80
6.4 Rearrangement Methods 84
6.5 The Synthesis of Amino Acids 85
6.6 The Synthesis of Heterocyclic Compounds 87
7 Functional Group Transformations 96
7.1 Oxidation 96
7.2 Reduction 103
7.3 Halogenation 111
8 Protecting Groups 126
8.1 Protection of Functional Groups 126
8.2 Peptide Synthesis 133
8.3 Combinatorial Synthesis 136
9 Some Examples of Total Syntheses 142
9.1 Introduction 142
9.2 p-Eudesmol 143
9.3 Griseofulvin 144
9.4 Thiamine (Vitamin Bj) 147
9.5 Prostaglandins 150
Further Reading 153
Answers to Problems 157
Subject Index 173
|
| adam_txt |
Contents
1 Introduction 1
1.1 Synthetic Strategies 1
1.2 Steric Factors 3
1.3 Criteria for Evaluating Synthetic Routes 3
1.4 Some Synthetic Terms 6
1.5 Learning to Apply Synthetic Methods 6
2 Organometallic and Ylide Methods of 9
Carbon-Carbon Bond Formation
2.1 Introduction 9
2.2 Reactions of Organometallic Compounds 11
2.3 Acetylides and Nitriles 20
2.4 Ylide Reactions 22
2.5 Silicon and Boron in C-C Bond Formation 26
3 Carbonyl Activation and Enolate Chemistry 32
in Carbon-Carbon Bond Formation
3.1 Introduction 32
3.2 Alkylation Reactions 36
3.3 Enolate Anions in Carbonyl Addition Reactions 39
3.4 The Stereochemistry of Condensation Reactions 48
4 Carbocations in Synthesis 54
4.1 Introduction 54
4.2 Alkyl Carbocations: the Friedel-Crafts Alkylation 55
4.3 Carbocations Derived from Aldehydes and Ketones 56
4.4 Acylium Carbocations: the Friedel-Crafts Acylation 57
4.5 Acid-catalysed Rearrangement Reactions 58
5 Free Radical and Pericyclic Reactions in the 64
Formation of Carbon-Carbon Bonds
5.1 Carbon Radical Reactions 64
5.2 Radical Addition Reactions 68
5.3 Carbenes 69
5.4 Alkene Metathesis 70
•5.5 The Diels-Alder Reaction 71
5.6 The Ene Reaction 73
5.7 The Cope and Claisen Rearrangements 73
6 Methods of Making Carbon-Nitrogen Bonds 78
6.1 Introduction 78
6.2 Electrophilic Methods of Making C-N Bonds 79
6.3 Nucleophilic Methods of Making C-N Bonds 80
6.4 Rearrangement Methods 84
6.5 The Synthesis of Amino Acids 85
6.6 The Synthesis of Heterocyclic Compounds 87
7 Functional Group Transformations 96
7.1 Oxidation 96
7.2 Reduction 103
7.3 Halogenation 111
8 Protecting Groups 126
8.1 Protection of Functional Groups 126
8.2 Peptide Synthesis 133
8.3 Combinatorial Synthesis 136
9 Some Examples of Total Syntheses 142
9.1 Introduction 142
9.2 p-Eudesmol 143
9.3 Griseofulvin 144
9.4 Thiamine (Vitamin Bj) 147
9.5 Prostaglandins 150
Further Reading 153
Answers to Problems 157
Subject Index 173 |
| any_adam_object | 1 |
| any_adam_object_boolean | 1 |
| author | Hanson, James R. |
| author_facet | Hanson, James R. |
| author_role | aut |
| author_sort | Hanson, James R. |
| author_variant | j r h jr jrh |
| building | Verbundindex |
| bvnumber | BV021692181 |
| callnumber-first | Q - Science |
| callnumber-label | QD262 |
| callnumber-raw | QD262 |
| callnumber-search | QD262 |
| callnumber-sort | QD 3262 |
| callnumber-subject | QD - Chemistry |
| classification_rvk | VK 5501 |
| ctrlnum | (OCoLC)248805036 (DE-599)BVBBV021692181 |
| dewey-full | 547.2 |
| dewey-hundreds | 500 - Natural sciences and mathematics |
| dewey-ones | 547 - Organic chemistry |
| dewey-raw | 547.2 |
| dewey-search | 547.2 |
| dewey-sort | 3547.2 |
| dewey-tens | 540 - Chemistry and allied sciences |
| discipline | Chemie / Pharmazie |
| discipline_str_mv | Chemie / Pharmazie |
| format | Book |
| fullrecord | <?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01488nam a2200397 cb4500</leader><controlfield tag="001">BV021692181</controlfield><controlfield tag="003">DE-604</controlfield><controlfield tag="005">00000000000000.0</controlfield><controlfield tag="007">t</controlfield><controlfield tag="008">060810s2002 a||| |||| 00||| eng d</controlfield><datafield tag="020" ind1=" " ind2=" "><subfield code="a">0854046828</subfield><subfield code="9">0-85404-682-8</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(OCoLC)248805036</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-599)BVBBV021692181</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-604</subfield><subfield code="b">ger</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1="0" ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="049" ind1=" " ind2=" "><subfield code="a">DE-19</subfield><subfield code="a">DE-634</subfield></datafield><datafield tag="050" ind1=" " ind2="0"><subfield code="a">QD262</subfield></datafield><datafield tag="082" ind1="0" ind2=" "><subfield code="a">547.2</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">VK 5501</subfield><subfield code="0">(DE-625)147401:254</subfield><subfield code="2">rvk</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Hanson, James R.</subfield><subfield code="e">Verfasser</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Organic synthetic methods</subfield><subfield code="c">James R. Hanson</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="a">Cambridge, UK</subfield><subfield code="b">Royal Soc. of Chemistry</subfield><subfield code="c">2002</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">VII, 175 S.</subfield><subfield code="b">Ill.</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="b">n</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="b">nc</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="490" ind1="1" ind2=" "><subfield code="a">Tutorial chemistry texts</subfield><subfield code="v">12</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Organic compounds</subfield><subfield code="x">Synthesis</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Organic compounds</subfield><subfield code="x">Synthesis</subfield><subfield code="v">Problems, exercises, etc</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Organische Synthese</subfield><subfield code="0">(DE-588)4075695-6</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="655" ind1=" " ind2="7"><subfield code="0">(DE-588)4123623-3</subfield><subfield code="a">Lehrbuch</subfield><subfield code="2">gnd-content</subfield></datafield><datafield tag="689" ind1="0" ind2="0"><subfield code="a">Organische Synthese</subfield><subfield code="0">(DE-588)4075695-6</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="0" ind2=" "><subfield code="5">DE-604</subfield></datafield><datafield tag="830" ind1=" " ind2="0"><subfield code="a">Tutorial chemistry texts</subfield><subfield code="v">12</subfield><subfield code="w">(DE-604)BV035419963</subfield><subfield code="9">12</subfield></datafield><datafield tag="856" ind1="4" ind2="2"><subfield code="m">HBZ Datenaustausch</subfield><subfield code="q">application/pdf</subfield><subfield code="u">http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=014906236&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA</subfield><subfield code="3">Inhaltsverzeichnis</subfield></datafield><datafield tag="999" ind1=" " ind2=" "><subfield code="a">oai:aleph.bib-bvb.de:BVB01-014906236</subfield></datafield></record></collection> |
| genre | (DE-588)4123623-3 Lehrbuch gnd-content |
| genre_facet | Lehrbuch |
| id | DE-604.BV021692181 |
| illustrated | Illustrated |
| index_date | 2024-07-02T15:14:45Z |
| indexdate | 2024-07-09T20:41:47Z |
| institution | BVB |
| isbn | 0854046828 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-014906236 |
| oclc_num | 248805036 |
| open_access_boolean | |
| owner | DE-19 DE-BY-UBM DE-634 |
| owner_facet | DE-19 DE-BY-UBM DE-634 |
| physical | VII, 175 S. Ill. |
| publishDate | 2002 |
| publishDateSearch | 2002 |
| publishDateSort | 2002 |
| publisher | Royal Soc. of Chemistry |
| record_format | marc |
| series | Tutorial chemistry texts |
| series2 | Tutorial chemistry texts |
| spelling | Hanson, James R. Verfasser aut Organic synthetic methods James R. Hanson Cambridge, UK Royal Soc. of Chemistry 2002 VII, 175 S. Ill. txt rdacontent n rdamedia nc rdacarrier Tutorial chemistry texts 12 Organic compounds Synthesis Organic compounds Synthesis Problems, exercises, etc Organische Synthese (DE-588)4075695-6 gnd rswk-swf (DE-588)4123623-3 Lehrbuch gnd-content Organische Synthese (DE-588)4075695-6 s DE-604 Tutorial chemistry texts 12 (DE-604)BV035419963 12 HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=014906236&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Hanson, James R. Organic synthetic methods Tutorial chemistry texts Organic compounds Synthesis Organic compounds Synthesis Problems, exercises, etc Organische Synthese (DE-588)4075695-6 gnd |
| subject_GND | (DE-588)4075695-6 (DE-588)4123623-3 |
| title | Organic synthetic methods |
| title_auth | Organic synthetic methods |
| title_exact_search | Organic synthetic methods |
| title_exact_search_txtP | Organic synthetic methods |
| title_full | Organic synthetic methods James R. Hanson |
| title_fullStr | Organic synthetic methods James R. Hanson |
| title_full_unstemmed | Organic synthetic methods James R. Hanson |
| title_short | Organic synthetic methods |
| title_sort | organic synthetic methods |
| topic | Organic compounds Synthesis Organic compounds Synthesis Problems, exercises, etc Organische Synthese (DE-588)4075695-6 gnd |
| topic_facet | Organic compounds Synthesis Organic compounds Synthesis Problems, exercises, etc Organische Synthese Lehrbuch |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=014906236&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| volume_link | (DE-604)BV035419963 |
| work_keys_str_mv | AT hansonjamesr organicsyntheticmethods |