Principles of development:
Gespeichert in:
Format: | Buch |
---|---|
Sprache: | English |
Veröffentlicht: |
Oxford [u.a.]
Oxford Univ. Press
2007
|
Ausgabe: | 3. ed. |
Schlagworte: | |
Online-Zugang: | http://www.oxfordtextbooks.co.uk/orc/wolpert3e/ Inhaltsverzeichnis |
Beschreibung: | XXIII, 551 S. zahlr. Ill., graph. Darst. |
ISBN: | 0199275378 9780199275373 019927536X 9780199275366 |
Internformat
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245 | 1 | 0 | |a Principles of development |c Lewis Wolpert ... |
250 | |a 3. ed. | ||
264 | 1 | |a Oxford [u.a.] |b Oxford Univ. Press |c 2007 | |
300 | |a XXIII, 551 S. |b zahlr. Ill., graph. Darst. | ||
336 | |b txt |2 rdacontent | ||
337 | |b n |2 rdamedia | ||
338 | |b nc |2 rdacarrier | ||
650 | 4 | |a Biologie du développement | |
650 | 4 | |a Developmental Biology | |
650 | 4 | |a Developmental biology | |
650 | 0 | 7 | |a Entwicklungsbiologie |0 (DE-588)4152440-8 |2 gnd |9 rswk-swf |
655 | 7 | |0 (DE-588)4123623-3 |a Lehrbuch |2 gnd-content | |
689 | 0 | 0 | |a Entwicklungsbiologie |0 (DE-588)4152440-8 |D s |
689 | 0 | |C b |5 DE-604 | |
700 | 1 | |a Wolpert, Lewis |d 1929-2021 |e Sonstige |0 (DE-588)134101936 |4 oth | |
856 | 4 | |u http://www.oxfordtextbooks.co.uk/orc/wolpert3e/ | |
856 | 4 | 2 | |m Digitalisierung UB Regensburg |q application/pdf |u http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=014832580&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |3 Inhaltsverzeichnis |
999 | |a oai:aleph.bib-bvb.de:BVB01-014832580 |
Datensatz im Suchindex
_version_ | 1804135407135227904 |
---|---|
adam_text | Contents
History and basic concepts
The origins of developmental biology
1.1
and preformation
■ BoxiA
1.2
development and heredity
1.3
1.4
of cells could determine the development of neighboring cells
і
the coming together of genetics and development
1.6
of model organisms
1.7
spontaneous mutations
A conceptual tool kit
1.8
of pattern, change in form, cell differentiation, and growth
■ Box IB Germ layers
1.9
action and developmental processes
їло
proteins are made
і
the control of complex control regions
і
becomes determined at different times
1.13
from each other
1.14
the state of the cell
1.15
of positional information
1.16
1.17
asymmetric celt division can make cells different
from each other
1.18
a descriptive program
1.19
by a variety of means
1.20
is due to the complexity of cells themselves
Development of
the Drosophila body plan
Drosophila life cycle and overall development
2.1
syncytium
2.2
segmentation, <md the formation of the larv.il nervous
system
2.3
through several larval stages, pupates, and then undergoes
morphogenesis to become an adult
2.4
identified in Drosophi/o through induced mutation
and large-scale genetic screening
■ Box2A Mutagenesis and genetic screening strategy
for identifying developmental mutants in Drowphila
Setting up the body axes
2.5
embryo is still
2.6
the early stage of Omsophila development
2.7
the antero-posterior axis
2.8
gradient of morphogen
2.9
of
2.10
the embryo are specified by cell-surface receptor
activation
2.11
specified by localization of maternal proteins in
the egg
2.12
axis is provided by the Dorsal protein
■ Box2B The Toll signaling pathway: a multifunctional
pathway
Localization of maternal determinants during
oogénesis
2.13
is specified by signals from the preceding egg chamber
and by interactions of the oocyte with follicle cells
2.14
movement of the oocyte nucleus followed by signaling
between oocyte and follicle cells
CONTENTS
Patterning the early embryo
2.15
the
2.16
to pattern the dorsal region
2.17
regions by gap-gene expression
2.18
the anterior expression of hunchback
2.19
and represses other gap genes
■ Box2C P-element-mediated transformation
Activation of the pair-rule genes and
the establishment of parasegments
2.20
pair-rule genes in a periodic pattern
2.21
gene expression
Segmentation genes and compartments
2.22
a cell-lineage boundary and defines a compartment
■ Box2D Genetic mosaics and mitotic recombination
2.23
boundaries and set up a focus of signaling at
the boundary that patterns the segment
2.24
in an
■
2.25
patterning the body plan
Specification of segment identity
2.26
genes of the Antennapedia and bithorax complexes
2.27
are responsible for diversification of the posterior
segments
2.28
of anterior regions
2.29
the order of genes along the chromosome
2.30
other than the Hox genes
■ Box2F Targeted gene expression and misexpression
screening
Patterning the vertebrate
body plan I: axes
Vertebrate life cycles and outlines of development
3.1
for developmental studies
■ Box
3.2
undivided yolk
3.3
of cells overlying a massive yolk
■ ВохЗВ
3.4
the allocation of cells to form the placenta and
extra-embryonic membranes
Setting up the body axes
3.5
determined in Xenopus and zebrafish
3.6
regulator
and the location of the main embryonic organizer
in Xenopus and zebrafish
■ ВохЗС
■
3.7
of Xenopus and zebrafish
3.8
of the chick blastoderm are related to the primitive streak
3.9
early in development
3.10
to produce left-right asymmetry of internal organs
The origin and specification of the germ layers
злі
constructed by following the fate of labeled cells
3.12
ona
3.13
have their fates determined and regulation is possible
■
3.14
specified by maternal factors, but the mesoderm is
induced from ectoderm by signals from the vegetal region
3.15
period in the
3.16
the mid-blastula transition
3.17
produced by the vegetal region, the organizer,
and the ventral mesoderm
3.18
as mesoderm inducers
3.19
involves the antagonistic actions of dorsalizing and
ventralizing factors
3.20
and mouse occurs during primitive-streak formation
3.21
responses could pattern the mesoderm
CONTENTS
xiii
Patterning the vertebrate
body plan II: the somites and early
nervous system
Somite formation and antero-posterior patterning
4.1
the antero-posterior axis
4.2
is specified by Hox gene expression
■
■
and gene knock-out
4.3
changes in axial patterning
4.4
mechanism
4.5
from the adjacent tissues
The role of the organizer and neural induction
4.6
during gastrulation
4.7
4.8
from the mesoderm
4.9
boundary
4.10
by boundaries of cell-lineage restriction
4.11
of the neural plate
4.12
in the developing hindbrain
4.13
into organ-forming regions that can still regulate
Development of nematodes,
sea urchins, ascidians, and slime molds
Nematodes
■
5.1
determined by asymmetric cell division
5.2
determined by cell-cell interactions
5.3
specify cell fate in the early nematode embryo
5.4
along the antero-posterior axis
5.5
is under genetic control that involves microRNAs
■ Box5B Gene silencing by microRNAs
5.6
of a small number of cells by short-range signals
from a single inducing cell
Echinoderms
5.7
a free-swimming larva
5.8
the animal-vegetal axis
5.9
to the plane of the first cleavage
5.10
yet considerable regulation is possible
5.11
acts as an organizer
5.12
by nuclear accumulation of
5.13
specification is known in considerable detail
Ascidians
5.14
cytoplasmic factors
5.15
ascidians require signals from the endoderm
Cellular slime molds
5.16
sorting and positional signaling
5.17
in the slime mold
Plant development
6.1
life cycle and a small diploid genome
Embryonic development
6.2
distinct stages
■ ВохбА
6.3
the embryonic apical-basal axis
6.4
and seedlings
■
Meristems 234
6.5
of self-renewing stem cells
6.6
constant by a feedback loop to the organizing center
6.7
can be changed by changing their position
6.8
can be deduced using
XIV
CONTENTS
6.9 Meristem
from other parts of the plant
ело
adaxial-abaxial axes of leaves developing from the
shoot meristem
6.11
and trichomes on leaves is generated by competition
and lateral inhibition
6.12
root apical meristems by a highly stereotyped pattern
of cell divisions
Flower development and control of flowering
6.13
in the flower
■
the Arabidopsis flower
6.14
as well as radially
6.15
meristem patterning
6.16
meristem is under environmental and genetic control
Morphogenesis: change
in form in the early embryo
Cell adhesion
■
7.1
differences in cell adhesiveness in different tissues
7.2
Cleavage and formation of the
7.3
the plane of cleavage at cell division
7.4
sea urchin
7.5 Ion transport is involved in fluid accumulation
in the frog blastocoel
7.6
Castrulation movements
7.7
migration and
■
7.8
changes in cell shape that are controlled by genes
that pattern the
7.9
myosin-dependent intercalation
7.10
in
filopodia
240
240
242
7.11
types of tissue movement
7.12
due to different types of cell intercalation
Neural-tube formation
7.13
in cell shape and cell migration
Cell migration
286
7.14
286
environmental cues and adhesive differences
246
7.15
288
246
and signal propagation
249
Directed dilation
290
7.16
290
250
occurs by directed dilation
7.17
291
251
elongates the nematode embryo
7.18
292
251
the form of a plant leaf
Cell differentiation
and stem cells
■
299
258
The control of gene expression
301
259
8.1
301
260
and tissue-specific transcriptional regulators
8.2
303
261
8.3
305
262
activity may depend on chemical and structural
modifications to chromatin as well as on regulatory
263
proteins
264
Models of cell differentiation
309
8.4
310
266
stem cells
8.5
312
267
control differentiation of the hematopoietic lineages
8.6
314
269
is controlled by regulatory sequences far distant from
269
the coding regions
8.7
316
270
irreversible
273
8.8
318
are continually replaced by derivatives of stem cells
8.9
319
275
transcription
8.10
320
276
withdrawal from the cell cycle, but is reversible
8.11
from stem cells in adults
321
CONTENTS
•
8.12
322
9.16
363
a great variety of different cell types
cell polarity
8.13
324
9.17
363
to the wing disc, except for the proximo-distal axis
The plasticity of gene expression
327
9.18
364
8.14
327
additional positional fields
development
9.19
366
8.15
329
determined by the homeotic selector genes
can be changed by cell fusion
9.20
367
8.16
330
cell-cell interactions
transdifferentiation
9.21
369
8.17
332
eye development
differentiate into many cell types in culture
8.18
medicine
332
Internal organs: blood vessels, lungs, kidneys,
heart, and teeth
371
Organogénesis
The vertebrate limb
9.1
9.2
9.3
are involved in specifying the position and type
of limb
9.4
outgrowth
9.5
the limb s antero-posterior axis
■
gradients
9.6
specified by a timing mechanism
9.7
9.8
signals give different limbs
9.9
for limb patterning
9.10
the development of the limb bud
9.11
tissue
■
9.12
and tendons is autonomous
9.13
and mechanical stimuli
9.14
of programmed cell death
Insect wings, legs, and eyes
9.ts Positional signals from the antero-posterior
and
the wing
340
340
341
341
343
345
347
349
350
351
351
353
354
355
356
357
357
358
359
9.22
followed by angiogenesis
9.23
vertebrates branch using similar mechanisms
9.24
reciprocal induction by the ureteric bud and surrounding
mesenchyme
9.25
involves specification of a mesodermal tube that is
patterned along its long axis
9.26
Development of
the nervous system
Specification of cell identity in the nervous system
10.1
10.2
in gene expression are involved in the development
of the Drosophila nervous system
10.3
Drosophila are already specified in the
10.4
the neural plate
10.5
involves lateral inhibition
10.6
of the neural tube and migrate outwards
10.7
the
on ventral and dorsal signals
Neuronal
10.8
by the growing axon
10.9
muscle-specific connections
10.10
attracted and repelled
xvi
CONTENTS
10.11
connections on the tectum to form a retino-tectal map
Synapse formation and refinement
10.12
interactions
10.13
10.14 Neuronal
intrinsic and extrinsic factors
10.15
activity
406
409
411
412
413
414
Growth and post-embryonic
development
and sex
Germ cells, fertilization,
The development of germ cells
11.1
germplasm in the egg
11.2
end of the Drosophila egg
11.3
to the
11.4
in chromosome number
11.5
amplification and contributions from other cells
11.6
growth are imprinted
Fertilization
11.7
between egg and sperm
11.8
block polyspermy
и
in egg activation
Determination of the sexual phenotype
ilio
is on the
11.11 Mammalian sexual phenotype is regulated
by gonadal hormones
11.12
is the number of X chromosomes, and is cell autonomous
11.13
is determined by the number of X chromosomes
11.14
but some produce unisexual flowers
11.15
on cell signals and genetic constitution
11.16
compensation of X-linked genes
Growth
12.1
cell enlargement, or accretion
12.2
an intrinsic program
12.3
signals and intrinsic growth programs
12.4
dimension rather than cell number
12.5
12.6
plates
451
452
452
454
455
457
458
422
422
12.7
on tension
460
425
12.8
that control cell multiplication and differentiation
461
425
12.9
463
Molting and metamorphosis
465
426
12.10
465
427
12.11
and hormonal control
466
427
Aging and senescence
469
12.12
470
432
432
12.13
senescence
471
434
Regeneration
435
Limb and organ regeneration
476
13.1
dedifferentiation and growth
477
437
437
13.2
positional values distal to the site of amputation
480
438
13.3
positional values in regenerating limbs
482
439
13.4
by both proximo-distal and circumferential growth
483
441
13.5
involve dedifferentiation
486
442
13.6
can regenerate
486
443
Regeneration in Hydra
488
444
13.7
does not require growth
488
13.8
organizing region and as an inhibitor of inappropriate
head formation
489
CONTENTS
XVII
13.9
for in terms of two gradients
13.10
similar to those expressed in animal embryos
490
492
Evolution and development
14.1
for development
The evolutionary modification of embryonic
development
14.2
during evolution
14.3
14.4
evolutionarily conserved developmental mechanisms
14.5
duplication
14.6
elaboration of vertebrate and arthropod body plans
14.7
insects is dependent on Hox gene expression
14.8
is similar, but the
14.9
a few genes
Changes in the timing of developmental processes
14.10
of organisms
14.11
changed during evolution
The evolution of development
14.12
single-celled ancestors is still highly speculative
|
adam_txt |
Contents
History and basic concepts
The origins of developmental biology
1.1
and preformation
■ BoxiA
1.2
development and heredity
1.3
1.4
of cells could determine the development of neighboring cells
і
the coming together of genetics and development
1.6
of model organisms
1.7
spontaneous mutations
A conceptual tool kit
1.8
of pattern, change in form, cell differentiation, and growth
■ Box IB Germ layers
1.9
action and developmental processes
їло
proteins are made
і
the control of complex control regions
і
becomes determined at different times
1.13
from each other
1.14
the state of the cell
1.15
of positional information
1.16
1.17
asymmetric celt division can make cells different
from each other
1.18
a descriptive program
1.19
by a variety of means
1.20
is due to the complexity of cells themselves
Development of
the Drosophila body plan
Drosophila life cycle and overall development
2.1
syncytium
2.2
segmentation, <md the formation of the larv.il nervous
system
2.3
through several larval stages, pupates, and then undergoes
morphogenesis to become an adult
2.4
identified in Drosophi/o through induced mutation
and large-scale genetic screening
■ Box2A Mutagenesis and genetic screening strategy
for identifying developmental mutants in Drowphila
Setting up the body axes
2.5
embryo is still
2.6
the early stage of Omsophila development
2.7
the antero-posterior axis
2.8
gradient of morphogen
2.9
of
2.10
the embryo are specified by cell-surface receptor
activation
2.11
specified by localization of maternal proteins in
the egg
2.12
axis is provided by the Dorsal protein
■ Box2B The Toll signaling pathway: a multifunctional
pathway
Localization of maternal determinants during
oogénesis
2.13
is specified by signals from the preceding egg chamber
and by interactions of the oocyte with follicle cells
2.14
movement of the oocyte nucleus followed by signaling
between oocyte and follicle cells
CONTENTS
Patterning the early embryo
2.15
the
2.16
to pattern the dorsal region
2.17
regions by gap-gene expression
2.18
the anterior expression of hunchback
2.19
and represses other gap genes
■ Box2C P-element-mediated transformation
Activation of the pair-rule genes and
the establishment of parasegments
2.20
pair-rule genes in a periodic pattern
2.21
gene expression
Segmentation genes and compartments
2.22
a cell-lineage boundary and defines a compartment
■ Box2D Genetic mosaics and mitotic recombination
2.23
boundaries and set up a focus of signaling at
the boundary that patterns the segment
2.24
in an
■
2.25
patterning the body plan
Specification of segment identity
2.26
genes of the Antennapedia and bithorax complexes
2.27
are responsible for diversification of the posterior
segments
2.28
of anterior regions
2.29
the order of genes along the chromosome
2.30
other than the Hox genes
■ Box2F Targeted gene expression and misexpression
screening
Patterning the vertebrate
body plan I: axes
Vertebrate life cycles and outlines of development
3.1
for developmental studies
■ Box
3.2
undivided yolk
3.3
of cells overlying a massive yolk
■ ВохЗВ
3.4
the allocation of cells to form the placenta and
extra-embryonic membranes
Setting up the body axes
3.5
determined in Xenopus and zebrafish
3.6
regulator
and the location of the main embryonic organizer
in Xenopus and zebrafish
■ ВохЗС
■
3.7
of Xenopus and zebrafish
3.8
of the chick blastoderm are related to the primitive streak
3.9
early in development
3.10
to produce left-right asymmetry of internal organs
The origin and specification of the germ layers
злі
constructed by following the fate of labeled cells
3.12
ona
3.13
have their fates determined and regulation is possible
■
3.14
specified by maternal factors, but the mesoderm is
induced from ectoderm by signals from the vegetal region
3.15
period in the
3.16
the mid-blastula transition
3.17
produced by the vegetal region, the organizer,
and the ventral mesoderm
3.18
as mesoderm inducers
3.19
involves the antagonistic actions of dorsalizing and
ventralizing factors
3.20
and mouse occurs during primitive-streak formation
3.21
responses could pattern the mesoderm
CONTENTS
xiii
Patterning the vertebrate
body plan II: the somites and early
nervous system
Somite formation and antero-posterior patterning
4.1
the antero-posterior axis
4.2
is specified by Hox gene expression
■
■
and gene knock-out
4.3
changes in axial patterning
4.4
mechanism
4.5
from the adjacent tissues
The role of the organizer and neural induction
4.6
during gastrulation
4.7
4.8
from the mesoderm
4.9
boundary
4.10
by boundaries of cell-lineage restriction
4.11
of the neural plate
4.12
in the developing hindbrain
4.13
into organ-forming regions that can still regulate
Development of nematodes,
sea urchins, ascidians, and slime molds
Nematodes
■
5.1
determined by asymmetric cell division
5.2
determined by cell-cell interactions
5.3
specify cell fate in the early nematode embryo
5.4
along the antero-posterior axis
5.5
is under genetic control that involves microRNAs
■ Box5B Gene silencing by microRNAs
5.6
of a small number of cells by short-range signals
from a single inducing cell
Echinoderms
5.7
a free-swimming larva
5.8
the animal-vegetal axis
5.9
to the plane of the first cleavage
5.10
yet considerable regulation is possible
5.11
acts as an organizer
5.12
by nuclear accumulation of
5.13
specification is known in considerable detail
Ascidians
5.14
cytoplasmic factors
5.15
ascidians require signals from the endoderm
Cellular slime molds
5.16
sorting and positional signaling
5.17
in the slime mold
Plant development
6.1
life cycle and a small diploid genome
Embryonic development
6.2
distinct stages
■ ВохбА
6.3
the embryonic apical-basal axis
6.4
and seedlings
■
Meristems 234
6.5
of self-renewing stem cells
6.6
constant by a feedback loop to the organizing center
6.7
can be changed by changing their position
6.8
can be deduced using
XIV
CONTENTS
6.9 Meristem
from other parts of the plant
ело
adaxial-abaxial axes of leaves developing from the
shoot meristem
6.11
and trichomes on leaves is generated by competition
and lateral inhibition
6.12
root apical meristems by a highly stereotyped pattern
of cell divisions
Flower development and control of flowering
6.13
in the flower
■
the Arabidopsis flower
6.14
as well as radially
6.15
meristem patterning
6.16
meristem is under environmental and genetic control
Morphogenesis: change
in form in the early embryo
Cell adhesion
■
7.1
differences in cell adhesiveness in different tissues
7.2
Cleavage and formation of the
7.3
the plane of cleavage at cell division
7.4
sea urchin
7.5 Ion transport is involved in fluid accumulation
in the frog blastocoel
7.6
Castrulation movements
7.7
migration and
■
7.8
changes in cell shape that are controlled by genes
that pattern the
7.9
myosin-dependent intercalation
7.10
in
filopodia
240
240
242
7.11
types of tissue movement
7.12
due to different types of cell intercalation
Neural-tube formation
7.13
in cell shape and cell migration
Cell migration
286
7.14
286
environmental cues and adhesive differences
246
7.15
288
246
and signal propagation
249
Directed dilation
290
7.16
290
250
occurs by directed dilation
7.17
291
251
elongates the nematode embryo
7.18
292
251
the form of a plant leaf
Cell differentiation
and stem cells
■
299
258
The control of gene expression
301
259
8.1
301
260
and tissue-specific transcriptional regulators
8.2
303
261
8.3
305
262
activity may depend on chemical and structural
modifications to chromatin as well as on regulatory
263
proteins
264
Models of cell differentiation
309
8.4
310
266
stem cells
8.5
312
267
control differentiation of the hematopoietic lineages
8.6
314
269
is controlled by regulatory sequences far distant from
269
the coding regions
8.7
316
270
irreversible
273
8.8
318
are continually replaced by derivatives of stem cells
8.9
319
275
transcription
8.10
320
276
withdrawal from the cell cycle, but is reversible
8.11
from stem cells in adults
321
CONTENTS
•
8.12
322
9.16
363
a great variety of different cell types
cell polarity
8.13
324
9.17
363
to the wing disc, except for the proximo-distal axis
The plasticity of gene expression
327
9.18
364
8.14
327
additional positional fields
development
9.19
366
8.15
329
determined by the homeotic selector genes
can be changed by cell fusion
9.20
367
8.16
330
cell-cell interactions
transdifferentiation
9.21
369
8.17
332
eye development
differentiate into many cell types in culture
8.18
medicine
332
Internal organs: blood vessels, lungs, kidneys,
heart, and teeth
371
Organogénesis
The vertebrate limb
9.1
9.2
9.3
are involved in specifying the position and type
of limb
9.4
outgrowth
9.5
the limb's antero-posterior axis
■
gradients
9.6
specified by a timing mechanism
9.7
9.8
signals give different limbs
9.9
for limb patterning
9.10
the development of the limb bud
9.11
tissue
■
9.12
and tendons is autonomous
9.13
and mechanical stimuli
9.14
of programmed cell death
Insect wings, legs, and eyes
9.ts Positional signals from the antero-posterior
and
the wing
340
340
341
341
343
345
347
349
350
351
351
353
354
355
356
357
357
358
359
9.22
followed by angiogenesis
9.23
vertebrates branch using similar mechanisms
9.24
reciprocal induction by the ureteric bud and surrounding
mesenchyme
9.25
involves specification of a mesodermal tube that is
patterned along its long axis
9.26
Development of
the nervous system
Specification of cell identity in the nervous system
10.1
10.2
in gene expression are involved in the development
of the Drosophila nervous system
10.3
Drosophila are already specified in the
10.4
the neural plate
10.5
involves lateral inhibition
10.6
of the neural tube and migrate outwards
10.7
the
on ventral and dorsal signals
Neuronal
10.8
by the growing axon
10.9
muscle-specific connections
10.10
attracted and repelled
xvi
CONTENTS
10.11
connections on the tectum to form a retino-tectal map
Synapse formation and refinement
10.12
interactions
10.13
10.14 Neuronal
intrinsic and extrinsic factors
10.15
activity
406
409
411
412
413
414
Growth and post-embryonic
development
and sex
Germ cells, fertilization,
The development of germ cells
11.1
germplasm in the egg
11.2
end of the Drosophila egg
11.3
to the
11.4
in chromosome number
11.5
amplification and contributions from other cells
11.6
growth are imprinted
Fertilization
11.7
between egg and sperm
11.8
block polyspermy
и
in egg activation
Determination of the sexual phenotype
ilio
is on the
11.11 Mammalian sexual phenotype is regulated
by gonadal hormones
11.12
is the number of X chromosomes, and is cell autonomous
11.13
is determined by the number of X chromosomes
11.14
but some produce unisexual flowers
11.15
on cell signals and genetic constitution
11.16
compensation of X-linked genes
Growth
12.1
cell enlargement, or accretion
12.2
an intrinsic program
12.3
signals and intrinsic growth programs
12.4
dimension rather than cell number
12.5
12.6
plates
451
452
452
454
455
457
458
422
422
12.7
on tension
460
425
12.8
that control cell multiplication and differentiation
461
425
12.9
463
Molting and metamorphosis
465
426
12.10
465
427
12.11
and hormonal control
466
427
Aging and senescence
469
12.12
470
432
432
12.13
senescence
471
434
Regeneration
435
Limb and organ regeneration
476
13.1
dedifferentiation and growth
477
437
437
13.2
positional values distal to the site of amputation
480
438
13.3
positional values in regenerating limbs
482
439
13.4
by both proximo-distal and circumferential growth
483
441
13.5
involve dedifferentiation
486
442
13.6
can regenerate
486
443
Regeneration in Hydra
488
444
13.7
does not require growth
488
13.8
organizing region and as an inhibitor of inappropriate
head formation
489
CONTENTS
XVII
13.9
for in terms of two gradients
13.10
similar to those expressed in animal embryos
490
492
Evolution and development
14.1
for development
The evolutionary modification of embryonic
development
14.2
during evolution
14.3
14.4
evolutionarily conserved developmental mechanisms
14.5
duplication
14.6
elaboration of vertebrate and arthropod body plans
14.7
insects is dependent on Hox gene expression
14.8
is similar, but the
14.9
a few genes
Changes in the timing of developmental processes
14.10
of organisms
14.11
changed during evolution
The evolution of development
14.12
single-celled ancestors is still highly speculative |
any_adam_object | 1 |
any_adam_object_boolean | 1 |
author_GND | (DE-588)134101936 |
building | Verbundindex |
bvnumber | BV021617466 |
callnumber-first | Q - Science |
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classification_rvk | WX 6000 |
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ctrlnum | (OCoLC)70164441 (DE-599)BVBBV021617466 |
dewey-full | 571.8 |
dewey-hundreds | 500 - Natural sciences and mathematics |
dewey-ones | 571 - Physiology & related subjects |
dewey-raw | 571.8 |
dewey-search | 571.8 |
dewey-sort | 3571.8 |
dewey-tens | 570 - Biology |
discipline | Biologie |
discipline_str_mv | Biologie |
edition | 3. ed. |
format | Book |
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genre_facet | Lehrbuch |
id | DE-604.BV021617466 |
illustrated | Illustrated |
index_date | 2024-07-02T14:52:39Z |
indexdate | 2024-07-09T20:40:01Z |
institution | BVB |
isbn | 0199275378 9780199275373 019927536X 9780199275366 |
language | English |
oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-014832580 |
oclc_num | 70164441 |
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physical | XXIII, 551 S. zahlr. Ill., graph. Darst. |
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publisher | Oxford Univ. Press |
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spelling | Principles of development Lewis Wolpert ... 3. ed. Oxford [u.a.] Oxford Univ. Press 2007 XXIII, 551 S. zahlr. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Biologie du développement Developmental Biology Developmental biology Entwicklungsbiologie (DE-588)4152440-8 gnd rswk-swf (DE-588)4123623-3 Lehrbuch gnd-content Entwicklungsbiologie (DE-588)4152440-8 s b DE-604 Wolpert, Lewis 1929-2021 Sonstige (DE-588)134101936 oth http://www.oxfordtextbooks.co.uk/orc/wolpert3e/ Digitalisierung UB Regensburg application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=014832580&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
spellingShingle | Principles of development Biologie du développement Developmental Biology Developmental biology Entwicklungsbiologie (DE-588)4152440-8 gnd |
subject_GND | (DE-588)4152440-8 (DE-588)4123623-3 |
title | Principles of development |
title_auth | Principles of development |
title_exact_search | Principles of development |
title_exact_search_txtP | Principles of development |
title_full | Principles of development Lewis Wolpert ... |
title_fullStr | Principles of development Lewis Wolpert ... |
title_full_unstemmed | Principles of development Lewis Wolpert ... |
title_short | Principles of development |
title_sort | principles of development |
topic | Biologie du développement Developmental Biology Developmental biology Entwicklungsbiologie (DE-588)4152440-8 gnd |
topic_facet | Biologie du développement Developmental Biology Developmental biology Entwicklungsbiologie Lehrbuch |
url | http://www.oxfordtextbooks.co.uk/orc/wolpert3e/ http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=014832580&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
work_keys_str_mv | AT wolpertlewis principlesofdevelopment |