Non-viral gene therapy: gene design and delivery
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
Tokyo [u.a.]
Springer
2005
|
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis Klappentext |
| Beschreibung: | Literaturangaben |
| Beschreibung: | XII, 487 S. Ill., graph. Darst. |
| ISBN: | 4431251227 |
Internformat
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| 245 | 1 | 0 | |a Non-viral gene therapy |b gene design and delivery |c K. Taira ... (eds.) |
| 264 | 1 | |a Tokyo [u.a.] |b Springer |c 2005 | |
| 300 | |a XII, 487 S. |b Ill., graph. Darst. | ||
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| 650 | 4 | |a Drug Delivery Systems |x methods | |
| 650 | 4 | |a Drugs |x Dosage forms | |
| 650 | 4 | |a Gene Therapy |x methods | |
| 650 | 4 | |a Gene Transfer Techniques | |
| 650 | 4 | |a Gene therapy |x Methodology | |
| 650 | 4 | |a Genetic Vectors |x therapeutic use | |
| 650 | 4 | |a Genetic vectors |x Therapeutic use | |
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Datensatz im Suchindex
| _version_ | 1804135343199354880 |
|---|---|
| adam_text | Contents
Foreword
Preface
1.
Recent Progress in Non-viral Gene Delivery
C.C. Conwell and L. Huang
Physical Chemistry of DNA-Carrier Complexes
K. Yoshikawa and Y. Yoshikawa
Liposomes
K. Maruyama
Polymeric Gene Carriers
T. Hashimoto and T. Yamaoka
Development of a Supramolecular Nanocarrier for Gene Delivery
Based on Cationic Block Copolymers
Y. Yamasaki, W.-D. Jang, N. Nishiyama, N. Kanayama, and K. Kataoka
Chitosan
M. Hashimoto, Z. Yang.Y. Koya, and T. Sato
Dendrimers as
H.
Use of Synthetic Peptides for Non-viral Gene Delivery
T. Niidome and Y. Katayama
An Oligonucleotide Carrier Based on
K. Sakurai and S. Shinkai
Biological and Chemical Hybrid Vectors
M. Nakanishi
Contents
2.
Pharmacokinetics
H. Akita,
Active DNA Release
T.
Controlled
M. Yokoyama
Active Transport
T.
Controlled Intracellular Localization of Oligonucleotides by
Chemical Conjugation
T. Kubo, R. Bakalova, Z. Zhelev, H. Ohba, and M. Fujii
Functional Nucleotide Sequences Capable of Promoting Non-viral
Genetic Transfer
O. Mazda and T. Kishida
Shielding of Cationic Charge of the
Interactions for In Vivo Gene Delivery
Y. Koyama
In Vivo Gene Transfer by Ligand-Modified Gene Carriers
S. Kawakami and M. Hashida
Optimizing Polyplexes into Synthetic Viruses for Tumor-Targeted
Gene Therapy
E. Wagner, J. Kloeckner, and M. Ogris
Gene Transfer and Target Diseases
M. Harada-Shiba
Clinical Trials Using Non-viral Gene Delivery Systems
H.Yanagie
3.
Evaluation of Size and
Y. Hattori and M. Hashida
Observation of DNA/Carrier Complexes Under Fluorescence Microscopy
T. Ito,Y. Koyama, and K. Yoshikawa
Synthesis of Chemically Modified Chitosan and a Study of Its Gene
Transfection Efficiency
T. Satoh
Newly Designed
H. Kamiya, H. Tsuchiya, and H. Harashima
XII
Evaluation
Administration
T. Okuda, S. Kawakami, and M. Hashida............................ 323
Evaluation
Gene Carrier to Organs
T. Kawano and T. Niidome
Evaluation of the Immune Response After Administration of Plasmid
DNA-Non-viral Vector Complexes
F. Sakurai, Y. Takakura, and M. Hashida
Gateway RNAi
K.R. Madden,
4.
Design of Intracellularly Active Ribozymes and siRNAs
M. Miyagishi and K.
RNAi-Based Inhibition Specific for Mutant
Diseases: Sequence-Dependent and -Independent Discrimination of Mutant
and Wild-Type
T. Yokota
In Vivo RNA Interference: Another Tool in the Box?
S. Petit, E. Valentin, and K. Thiam
Suppression of Gene Expression via Chromatin Remodeling and
the siRNA-Induced Silencing of Transcription
H. Kawasaki, Y. Fukuda, K.
Intracellular Delivery of Nucleic Acids: Differences Between Transfection
and siFection Reflect Differences Between
Oligodeoxynucleotides and Oligonucleotides
M. Keller and
In
J. Yano, G.E. Smyth, K. Hirabayashi, and T. Ohgi
Enhancing RNAi with Synthetic RNA Duplexes
D.-H. Kim, M.A. Behlke,
Subject Index
Non-viral Gene
Gene Design and Delivery
The development of gene medicine based on the
concept of molecular therapy has opened new
medical horizons. Among the many techniques in
gene medicine, gene design and delivery are
especially significant in clinical applications. This
book presents state-of-the-art information on
non-viral gene-delivery techniques, covering a
broad spectrum of disciplines that include
chemistry, molecular biology, cell biology, and
pharmacokinetics. Major sections introduce
molecules for gene delivery and their properties;
technologies of controlled gene delivery in vitro
and in vivo; therapeutic genes and the status of
clinical applications; and the design of genes
based on current RNA technology, with
revolutionary developments in the world of RNAi
shown to be key factors in gene medicine. This
groundbreaking work is an invaluable resource
for researchers and engineers in genetic
engineering, molecular medicine,, biochemical
engineering, and biotechnology.
|
| adam_txt |
Contents
Foreword
Preface
1.
Recent Progress in Non-viral Gene Delivery
C.C. Conwell and L. Huang
Physical Chemistry of DNA-Carrier Complexes
K. Yoshikawa and Y. Yoshikawa
Liposomes
K. Maruyama
Polymeric Gene Carriers
T. Hashimoto and T. Yamaoka
Development of a Supramolecular Nanocarrier for Gene Delivery
Based on Cationic Block Copolymers
Y. Yamasaki, W.-D. Jang, N. Nishiyama, N. Kanayama, and K. Kataoka
Chitosan
M. Hashimoto, Z. Yang.Y. Koya, and T. Sato
Dendrimers as
H.
Use of Synthetic Peptides for Non-viral Gene Delivery
T. Niidome and Y. Katayama
An Oligonucleotide Carrier Based on
K. Sakurai and S. Shinkai
Biological and Chemical Hybrid Vectors
M. Nakanishi
Contents
2.
Pharmacokinetics
H. Akita,
Active DNA Release
T.
Controlled
M. Yokoyama
Active Transport
T.
Controlled Intracellular Localization of Oligonucleotides by
Chemical Conjugation
T. Kubo, R. Bakalova, Z. Zhelev, H. Ohba, and M. Fujii
Functional Nucleotide Sequences Capable of Promoting Non-viral
Genetic Transfer
O. Mazda and T. Kishida
Shielding of Cationic Charge of the
Interactions for In Vivo Gene Delivery
Y. Koyama
In Vivo Gene Transfer by Ligand-Modified Gene Carriers
S. Kawakami and M. Hashida
Optimizing Polyplexes into Synthetic Viruses for Tumor-Targeted
Gene Therapy
E. Wagner, J. Kloeckner, and M. Ogris
Gene Transfer and Target Diseases
M. Harada-Shiba
Clinical Trials Using Non-viral Gene Delivery Systems
H.Yanagie
3.
Evaluation of Size and
Y. Hattori and M. Hashida
Observation of DNA/Carrier Complexes Under Fluorescence Microscopy
T. Ito,Y. Koyama, and K. Yoshikawa
Synthesis of Chemically Modified Chitosan and a Study of Its Gene
Transfection Efficiency
T. Satoh
Newly Designed
H. Kamiya, H. Tsuchiya, and H. Harashima
XII
Evaluation
Administration
T. Okuda, S. Kawakami, and M. Hashida. 323
Evaluation
Gene Carrier to Organs
T. Kawano and T. Niidome
Evaluation of the Immune Response After Administration of Plasmid
DNA-Non-viral Vector Complexes
F. Sakurai, Y. Takakura, and M. Hashida
Gateway RNAi
K.R. Madden,
4.
Design of Intracellularly Active Ribozymes and siRNAs
M. Miyagishi and K.
RNAi-Based Inhibition Specific for Mutant
Diseases: Sequence-Dependent and -Independent Discrimination of Mutant
and Wild-Type
T. Yokota
In Vivo RNA Interference: Another Tool in the Box?
S. Petit, E. Valentin, and K. Thiam
Suppression of Gene Expression via Chromatin Remodeling and
the siRNA-Induced Silencing of Transcription
H. Kawasaki, Y. Fukuda, K.
Intracellular Delivery of Nucleic Acids: Differences Between Transfection
and siFection Reflect Differences Between
Oligodeoxynucleotides and Oligonucleotides
M. Keller and
In
J. Yano, G.E. Smyth, K. Hirabayashi, and T. Ohgi
Enhancing RNAi with Synthetic RNA Duplexes
D.-H. Kim, M.A. Behlke,
Subject Index
Non-viral Gene
Gene Design and Delivery
The development of gene medicine based on the
concept of molecular therapy has opened new
medical horizons. Among the many techniques in
gene medicine, gene design and delivery are
especially significant in clinical applications. This
book presents state-of-the-art information on
non-viral gene-delivery techniques, covering a
broad spectrum of disciplines that include
chemistry, molecular biology, cell biology, and
pharmacokinetics. Major sections introduce
molecules for gene delivery and their properties;
technologies of controlled gene delivery in vitro
and in vivo; therapeutic genes and the status of
clinical applications; and the design of genes
based on current RNA technology, with
revolutionary developments in the world of RNAi
shown to be key factors in gene medicine. This
groundbreaking work is an invaluable resource
for researchers and engineers in genetic
engineering, molecular medicine,, biochemical
engineering, and biotechnology. |
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| spelling | Non-viral gene therapy gene design and delivery K. Taira ... (eds.) Tokyo [u.a.] Springer 2005 XII, 487 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Literaturangaben Drug Delivery Systems methods Drugs Dosage forms Gene Therapy methods Gene Transfer Techniques Gene therapy Methodology Genetic Vectors therapeutic use Genetic vectors Therapeutic use Gentherapie (DE-588)4296957-8 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Gentherapie (DE-588)4296957-8 s DE-604 Taira, Kazunari Sonstige oth Digitalisierung UBRegensburg application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=014790582&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis Digitalisierung UB Regensburg application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=014790582&sequence=000002&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA Klappentext |
| spellingShingle | Non-viral gene therapy gene design and delivery Drug Delivery Systems methods Drugs Dosage forms Gene Therapy methods Gene Transfer Techniques Gene therapy Methodology Genetic Vectors therapeutic use Genetic vectors Therapeutic use Gentherapie (DE-588)4296957-8 gnd |
| subject_GND | (DE-588)4296957-8 (DE-588)4143413-4 |
| title | Non-viral gene therapy gene design and delivery |
| title_auth | Non-viral gene therapy gene design and delivery |
| title_exact_search | Non-viral gene therapy gene design and delivery |
| title_exact_search_txtP | Non-viral gene therapy gene design and delivery |
| title_full | Non-viral gene therapy gene design and delivery K. Taira ... (eds.) |
| title_fullStr | Non-viral gene therapy gene design and delivery K. Taira ... (eds.) |
| title_full_unstemmed | Non-viral gene therapy gene design and delivery K. Taira ... (eds.) |
| title_short | Non-viral gene therapy |
| title_sort | non viral gene therapy gene design and delivery |
| title_sub | gene design and delivery |
| topic | Drug Delivery Systems methods Drugs Dosage forms Gene Therapy methods Gene Transfer Techniques Gene therapy Methodology Genetic Vectors therapeutic use Genetic vectors Therapeutic use Gentherapie (DE-588)4296957-8 gnd |
| topic_facet | Drug Delivery Systems methods Drugs Dosage forms Gene Therapy methods Gene Transfer Techniques Gene therapy Methodology Genetic Vectors therapeutic use Genetic vectors Therapeutic use Gentherapie Aufsatzsammlung |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=014790582&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=014790582&sequence=000002&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA |
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