Cancer: cell structures, carcinogens and genomic instability
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
Basel [u.a.]
Birkhäuser
2006
|
| Schriftenreihe: | EXS
96 |
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis Klappentext |
| Beschreibung: | Literaturangaben |
| Beschreibung: | XI, 375 S. Ill., graph. Darst. |
| ISBN: | 9783764371562 3764371560 |
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| 245 | 1 | 0 | |a Cancer |b cell structures, carcinogens and genomic instability |c ed. by Leon P. Bignold |
| 264 | 1 | |a Basel [u.a.] |b Birkhäuser |c 2006 | |
| 300 | |a XI, 375 S. |b Ill., graph. Darst. | ||
| 336 | |b txt |2 rdacontent | ||
| 337 | |b n |2 rdamedia | ||
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| 490 | 1 | |a EXS |v 96 | |
| 500 | |a Literaturangaben | ||
| 650 | 4 | |a Cancer - Aspect génétique | |
| 650 | 4 | |a Cancer - Physiopathologie | |
| 650 | 4 | |a Cancérogenèse - Aspect moléculaire | |
| 650 | 4 | |a Cellules cancéreuses | |
| 650 | 4 | |a Cancer cells | |
| 650 | 4 | |a Cancer |x Genetic aspects | |
| 650 | 4 | |a Cancer |x Pathophysiology | |
| 650 | 4 | |a Carcinogenesis |x Molecular aspects | |
| 650 | 4 | |a Carcinogens | |
| 650 | 4 | |a Gene Expression Regulation, Neoplastic |x drug effects | |
| 650 | 4 | |a Genomic Instability | |
| 650 | 4 | |a Neoplasms |x etiology | |
| 650 | 4 | |a Neoplasms |x genetics | |
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Datensatz im Suchindex
| _version_ | 1804135343118614528 |
|---|---|
| adam_text | Contents
List of Contributors
Preface
Leon P. Bignold, B. L. D. Coghlan and H. P. A. Jersmann
Cancer morphology, carcinogenesis and genetic instability:
a background
Bojan Drobic,
James R. Davie
Abnormalities of chromatin in tumor cells
Sen Pathak andAsha S. Multani
Aneuploidy, stem cells and cancer
Andreas Luch
The mode of action of organic carcinogens on cellular structures
Troy R. Durham and Elizabeth T. Snow
Metal ions and carcinogenesis
David I. Pattison and Michael J. Davies
Actions of ultraviolet light on cellular structures
Carmel
Actions of radiation on living cells in the post-bystander era
Karl Munger,
Nadja
Viral carcinogenesis and genomic instability
Herman H. Cheung, Vinay Arora, Robert G. Korneluk
Abnormalities of cell structures in tumors: apoptosis in tumors
Jay Harper and Marsha A. Moses
Molecular regulation of tumor angiogenesis: mechanisms and
therapeutic implications
VI
Okio Hiño, Toshiyuki Kobayashi and Kazuo Okimoto
Genetic and environmental factors in hereditary predisposition
to tumors: a conceptual overview
Marianne Sowa, Benjamin J. Arthurs, Brian J.
and William F. Morgan
Effects of ionizing radiation on cellular structures, induced
instability and carcinogenesis
Stavroula Raptis and Bharati Bapat
Genetic instability in human tumors
William B. Coleman and Gregory J. Tsongalis
Molecular mechanisms of human carcinogenesis
Assam El-
Mechanisms of abnormal gene expression in tumor cells
Index
Caneen
Carcinogens and Genomic Instability
Leon P. Bignold (Editor)
Tumors can be induced by a variety of physical and chemical carcino¬
gens. The resulting tumor cells are usually abnormal in their morphol¬
ogy and behavior. Tumor cells transmit their abnormalities, which
often include morphological variability, to their daughter tumor cells.
Most theories of the pathogenesis of tumors suggest that carcinogens
in some way cause instability or other alterations of the genomes of
normal cells, which then cause the morphological and behavioral
changes.
This volume has fifteen chapters: a historical background, followed by
chapters on the cellular targets of known carcinogens, on the cellular
effects of specific carcinogenic factors (chemical, physical, viral and
inherited), on apoptosis and angiogenesis in tumors, on the issues of
genomic instability and epigenetic mechanisms in tumors. It provides
an up-to-date summary of key issues in cancer, and will be useful to
postgraduate students beginning research in any area of cancer, as
well as established cancer researchers who would like to keep abreast
of related fields of causation, morphology and cancer genetics.
Similarly, health workers in the fields of diagnosis, management or
prevention will find many of the chapters useful for updates in key
issues in the understanding of the nature of cancer.
|
| adam_txt |
Contents
List of Contributors
Preface
Leon P. Bignold, B. L. D. Coghlan and H. P. A. Jersmann
Cancer morphology, carcinogenesis and genetic instability:
a background
Bojan Drobic,
James R. Davie
Abnormalities of chromatin in tumor cells
Sen Pathak andAsha S. Multani
Aneuploidy, stem cells and cancer
Andreas Luch
The mode of action of organic carcinogens on cellular structures
Troy R. Durham and Elizabeth T. Snow
Metal ions and carcinogenesis
David I. Pattison and Michael J. Davies
Actions of ultraviolet light on cellular structures
Carmel
Actions of radiation on living cells in the "post-bystander" era
Karl Munger,
Nadja
Viral carcinogenesis and genomic instability
Herman H. Cheung, Vinay Arora, Robert G. Korneluk
Abnormalities of cell structures in tumors: apoptosis in tumors
Jay Harper and Marsha A. Moses
Molecular regulation of tumor angiogenesis: mechanisms and
therapeutic implications
VI
Okio Hiño, Toshiyuki Kobayashi and Kazuo Okimoto
Genetic and environmental factors in hereditary predisposition
to tumors: a conceptual overview
Marianne Sowa, Benjamin J. Arthurs, Brian J.
and William F. Morgan
Effects of ionizing radiation on cellular structures, induced
instability and carcinogenesis
Stavroula Raptis and Bharati Bapat
Genetic instability in human tumors
William B. Coleman and Gregory J. Tsongalis
Molecular mechanisms of human carcinogenesis
Assam El-
Mechanisms of abnormal gene expression in tumor cells
Index
Caneen
Carcinogens and Genomic Instability
Leon P. Bignold (Editor)
Tumors can be induced by a variety of physical and chemical carcino¬
gens. The resulting tumor cells are usually abnormal in their morphol¬
ogy and behavior. Tumor cells transmit their abnormalities, which
often include morphological variability, to their daughter tumor cells.
Most theories of the pathogenesis of tumors suggest that carcinogens
in some way cause instability or other alterations of the genomes of
normal cells, which then cause the morphological and behavioral
changes.
This volume has fifteen chapters: a historical background, followed by
chapters on the cellular targets of known carcinogens, on the cellular
effects of specific carcinogenic factors (chemical, physical, viral and
inherited), on apoptosis and angiogenesis in tumors, on the issues of
genomic instability and epigenetic mechanisms in tumors. It provides
an up-to-date summary of key issues in cancer, and will be useful to
postgraduate students beginning research in any area of cancer, as
well as established cancer researchers who would like to keep abreast
of related fields of causation, morphology and cancer genetics.
Similarly, health workers in the fields of diagnosis, management or
prevention will find many of the chapters useful for updates in key
issues in the understanding of the nature of cancer. |
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| spelling | Cancer cell structures, carcinogens and genomic instability ed. by Leon P. Bignold Basel [u.a.] Birkhäuser 2006 XI, 375 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier EXS 96 Literaturangaben Cancer - Aspect génétique Cancer - Physiopathologie Cancérogenèse - Aspect moléculaire Cellules cancéreuses Cancer cells Cancer Genetic aspects Cancer Pathophysiology Carcinogenesis Molecular aspects Carcinogens Gene Expression Regulation, Neoplastic drug effects Genomic Instability Neoplasms etiology Neoplasms genetics Krebszelle (DE-588)4128704-6 gnd rswk-swf Carcinogenese (DE-588)4069853-1 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Carcinogenese (DE-588)4069853-1 s DE-604 Krebszelle (DE-588)4128704-6 s Bignold, Leon P. Sonstige oth EXS 96 (DE-604)BV006943917 96 Digitalisierung UBRegensburg application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=014790533&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis Digitalisierung UB Regensburg application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=014790533&sequence=000002&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA Klappentext |
| spellingShingle | Cancer cell structures, carcinogens and genomic instability EXS Cancer - Aspect génétique Cancer - Physiopathologie Cancérogenèse - Aspect moléculaire Cellules cancéreuses Cancer cells Cancer Genetic aspects Cancer Pathophysiology Carcinogenesis Molecular aspects Carcinogens Gene Expression Regulation, Neoplastic drug effects Genomic Instability Neoplasms etiology Neoplasms genetics Krebszelle (DE-588)4128704-6 gnd Carcinogenese (DE-588)4069853-1 gnd |
| subject_GND | (DE-588)4128704-6 (DE-588)4069853-1 (DE-588)4143413-4 |
| title | Cancer cell structures, carcinogens and genomic instability |
| title_auth | Cancer cell structures, carcinogens and genomic instability |
| title_exact_search | Cancer cell structures, carcinogens and genomic instability |
| title_exact_search_txtP | Cancer cell structures, carcinogens and genomic instability |
| title_full | Cancer cell structures, carcinogens and genomic instability ed. by Leon P. Bignold |
| title_fullStr | Cancer cell structures, carcinogens and genomic instability ed. by Leon P. Bignold |
| title_full_unstemmed | Cancer cell structures, carcinogens and genomic instability ed. by Leon P. Bignold |
| title_short | Cancer |
| title_sort | cancer cell structures carcinogens and genomic instability |
| title_sub | cell structures, carcinogens and genomic instability |
| topic | Cancer - Aspect génétique Cancer - Physiopathologie Cancérogenèse - Aspect moléculaire Cellules cancéreuses Cancer cells Cancer Genetic aspects Cancer Pathophysiology Carcinogenesis Molecular aspects Carcinogens Gene Expression Regulation, Neoplastic drug effects Genomic Instability Neoplasms etiology Neoplasms genetics Krebszelle (DE-588)4128704-6 gnd Carcinogenese (DE-588)4069853-1 gnd |
| topic_facet | Cancer - Aspect génétique Cancer - Physiopathologie Cancérogenèse - Aspect moléculaire Cellules cancéreuses Cancer cells Cancer Genetic aspects Cancer Pathophysiology Carcinogenesis Molecular aspects Carcinogens Gene Expression Regulation, Neoplastic drug effects Genomic Instability Neoplasms etiology Neoplasms genetics Krebszelle Carcinogenese Aufsatzsammlung |
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