Complement and kidney disease:
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
Basel [u.a.]
Birkhäuser
2006
|
| Schriftenreihe: | Progress in inflammation research
|
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis Klappentext |
| Beschreibung: | Literaturangaben |
| Beschreibung: | XVI, 236 S. Ill., graph. Darst. |
| ISBN: | 9783764371661 3764371668 |
Internformat
MARC
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| 245 | 1 | 0 | |a Complement and kidney disease |c Peter F. Zipfel ed. |
| 264 | 1 | |a Basel [u.a.] |b Birkhäuser |c 2006 | |
| 300 | |a XVI, 236 S. |b Ill., graph. Darst. | ||
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| 490 | 0 | |a Progress in inflammation research | |
| 500 | |a Literaturangaben | ||
| 650 | 4 | |a Complement (Immunology) | |
| 650 | 4 | |a Complement System Proteins |x physiology | |
| 650 | 4 | |a Hemolytic-Uremic Syndrome | |
| 650 | 4 | |a Kidney Diseases |x etiology | |
| 650 | 4 | |a Kidneys |x Diseases |x Etiology | |
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Datensatz im Suchindex
| _version_ | 1804135342960279552 |
|---|---|
| adam_text | Contents
Abbreviations
List of contributors
Poem
Preface
Momir Macanovic and Peter
The complement system in renal diseases
Wuding Zhou and Steven H. Sacks
Complement in renal transplantation
Stefan P.
C1q and the glomerulonephritides: therapeutic approaches for the
treatment of complement-mediated kidney diseases
Joshua M. Thurman and V. Michael Holers
Complement deficient mice as model systems for kidney diseases
Marina Noris and Giuseppe Remuzzi
Non-Shiga toxin-associated hemolytic
Christine Skerka and
Role of complement and Factor
Timothy H.J. Goodship,
Genetic testing in atypical HUS and the role of membrane cofactor protein
(MCP;CD46) and Factor I
Maren Salzmann,
Markus Cybulla, Hartmut PH.
Towards a new classification of hemolytic
Reinhard Würzner and Lothar B. Zimmerhackl
Therapeutic strategies for atypical and recurrent hemolytic
syndromes (HUS)
Christoph Licht
Complement defects in children which result in kidney diseases:
diagnosis and therapy
Peter
The role of complement in membranoproliferative glomerulonephritis
Pearl L. Lewis
The experience of a patient advocacy group
Index
It is evident that a defective or deregulated complement system
results in kidney diseases. An important role of complement effector
and regulatory proteins in pathological settings of the kidney has
been demonstrated. A large panel of distinct human kidney diseases
is caused by defective complement control. Genetic analyses have
identified mutations in complement regulators that are associated
with these diseases. Mutations have been identified in the fluid-
phase alternative pathway regulator Factor
regulator membrane cofactor protein MCP (CD46). The functional
characterization of the mutant proteins allows the pathophysiological
events to be defined at a molecular level. These new concepts and
data on disease mechanisms enable new diagnostic and promising
therapeutic approaches for several human kidney diseases to be
established. Molecular biology, clinics and therapy are discussed in
this volume.
|
| adam_txt |
Contents
Abbreviations
List of contributors
Poem
Preface
Momir Macanovic and Peter
The complement system in renal diseases
Wuding Zhou and Steven H. Sacks
Complement in renal transplantation
Stefan P.
C1q and the glomerulonephritides: therapeutic approaches for the
treatment of complement-mediated kidney diseases
Joshua M. Thurman and V. Michael Holers
Complement deficient mice as model systems for kidney diseases
Marina Noris and Giuseppe Remuzzi
Non-Shiga toxin-associated hemolytic
Christine Skerka and
Role of complement and Factor
Timothy H.J. Goodship,
Genetic testing in atypical HUS and the role of membrane cofactor protein
(MCP;CD46) and Factor I
Maren Salzmann,
Markus Cybulla, Hartmut PH.
Towards a new classification of hemolytic
Reinhard Würzner and Lothar B. Zimmerhackl
Therapeutic strategies for atypical and recurrent hemolytic
syndromes (HUS)
Christoph Licht
Complement defects in children which result in kidney diseases:
diagnosis and therapy
Peter
The role of complement in membranoproliferative glomerulonephritis
Pearl L. Lewis
The experience of a patient advocacy group
Index
It is evident that a defective or deregulated complement system
results in kidney diseases. An important role of complement effector
and regulatory proteins in pathological settings of the kidney has
been demonstrated. A large panel of distinct human kidney diseases
is caused by defective complement control. Genetic analyses have
identified mutations in complement regulators that are associated
with these diseases. Mutations have been identified in the fluid-
phase alternative pathway regulator Factor
regulator membrane cofactor protein MCP (CD46). The functional
characterization of the mutant proteins allows the pathophysiological
events to be defined at a molecular level. These new concepts and
data on disease mechanisms enable new diagnostic and promising
therapeutic approaches for several human kidney diseases to be
established. Molecular biology, clinics and therapy are discussed in
this volume. |
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| id | DE-604.BV021574656 |
| illustrated | Illustrated |
| index_date | 2024-07-02T14:39:35Z |
| indexdate | 2024-07-09T20:38:59Z |
| institution | BVB |
| isbn | 9783764371661 3764371668 |
| language | English |
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| physical | XVI, 236 S. Ill., graph. Darst. |
| publishDate | 2006 |
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| series2 | Progress in inflammation research |
| spelling | Complement and kidney disease Peter F. Zipfel ed. Basel [u.a.] Birkhäuser 2006 XVI, 236 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Progress in inflammation research Literaturangaben Complement (Immunology) Complement System Proteins physiology Hemolytic-Uremic Syndrome Kidney Diseases etiology Kidneys Diseases Etiology Komplement Immunologie (DE-588)4120589-3 gnd rswk-swf Nierenkrankheit (DE-588)4075399-2 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Nierenkrankheit (DE-588)4075399-2 s Komplement Immunologie (DE-588)4120589-3 s DE-604 Zipfel, Peter F. 1954- Sonstige (DE-588)110935810 oth Digitalisierung UBRegensburg application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=014790418&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis Digitalisierung UB Regensburg application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=014790418&sequence=000002&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA Klappentext |
| spellingShingle | Complement and kidney disease Complement (Immunology) Complement System Proteins physiology Hemolytic-Uremic Syndrome Kidney Diseases etiology Kidneys Diseases Etiology Komplement Immunologie (DE-588)4120589-3 gnd Nierenkrankheit (DE-588)4075399-2 gnd |
| subject_GND | (DE-588)4120589-3 (DE-588)4075399-2 (DE-588)4143413-4 |
| title | Complement and kidney disease |
| title_auth | Complement and kidney disease |
| title_exact_search | Complement and kidney disease |
| title_exact_search_txtP | Complement and kidney disease |
| title_full | Complement and kidney disease Peter F. Zipfel ed. |
| title_fullStr | Complement and kidney disease Peter F. Zipfel ed. |
| title_full_unstemmed | Complement and kidney disease Peter F. Zipfel ed. |
| title_short | Complement and kidney disease |
| title_sort | complement and kidney disease |
| topic | Complement (Immunology) Complement System Proteins physiology Hemolytic-Uremic Syndrome Kidney Diseases etiology Kidneys Diseases Etiology Komplement Immunologie (DE-588)4120589-3 gnd Nierenkrankheit (DE-588)4075399-2 gnd |
| topic_facet | Complement (Immunology) Complement System Proteins physiology Hemolytic-Uremic Syndrome Kidney Diseases etiology Kidneys Diseases Etiology Komplement Immunologie Nierenkrankheit Aufsatzsammlung |
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