Sumoylation: molecular biology and biochemistry
This volume presents information on the history, evolution and mechanisms of sumoylation, discusses SUMO proteases, ligases and conjugation pathways, and reviews the impact on modification and nucleocytoplasmic transport, PML nuclear bodies, and transcriptional regulation. Specialist chapters cover...
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
Wymondham
Horizon Bioscience
2004
|
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis Klappentext |
| Zusammenfassung: | This volume presents information on the history, evolution and mechanisms of sumoylation, discusses SUMO proteases, ligases and conjugation pathways, and reviews the impact on modification and nucleocytoplasmic transport, PML nuclear bodies, and transcriptional regulation. Specialist chapters cover the role of sumoylation in yeast, viruses and the tumor suppressor p53. |
| Beschreibung: | X, 404 S. Ill., graph. Darst. |
| ISBN: | 0954523288 |
Internformat
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| 520 | 3 | |a This volume presents information on the history, evolution and mechanisms of sumoylation, discusses SUMO proteases, ligases and conjugation pathways, and reviews the impact on modification and nucleocytoplasmic transport, PML nuclear bodies, and transcriptional regulation. Specialist chapters cover the role of sumoylation in yeast, viruses and the tumor suppressor p53. | |
| 650 | 4 | |a Bacterial genetics | |
| 650 | 4 | |a Extrachromosomal DNA | |
| 650 | 4 | |a Gene expression | |
| 650 | 4 | |a Molecular biology | |
| 650 | 4 | |a Protein Processing, Post-Translational | |
| 650 | 4 | |a Small Ubiquitin-Related Modifier Proteins |x metabolism | |
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Datensatz im Suchindex
| _version_ | 1804135338804772864 |
|---|---|
| adam_text | Contents
Contents
Contributors
Preface
Chapter
Kirsten
Chapter
Christopher N.
Chapter
Yuan Chen
Chapter
Felicity Watts
Chapter
Andrea Pichler and
Chapter
and De-conjugation Pathways
Hisato Saitoh
Chapter
Yoshiko Kikuchi
Chapter
Valérie
Chapter
Michael J. Matunis
Chapter
David Girdwood, Michael H. Tatham and Ronald T. Hay
Chapter
Germán
Chapter
and of its Ubiquitin
Hideyo Yasuda
Index
iii
SUMOYLATION
MOLECULAR BIOLOGY
AND BIOCHEMISTRY
Sumoylation is a novel post-translational modification system,
biochemically analogous to, but functionally distinct from,
ubiquitinylation. Sumoylation involves the covalent attachment
of a SUMO (small ubiquitin-related modifier) to substrate
proteins. This modification system has crucial roles in many
different biological processes, including protein localization
and stability, transcriptional activities, nucleocytoplasmic
signalling and transport, and genome replication, as well
as the regulation of gene expression. The molecular and
biochemical mechanisms involved in sumoylation have
been the subject of intense interest in recent years. This
volume, edited and written by leading international experts,
is the first book to be devoted to sumoylation. It presents
information on the history, evolution and mechanisms
of sumoylation, discusses SUMO proteases,
conjugation pathways, and reviews the impact on modification
and nucleocytoplasmic transport, PML nuclear bodies and
transcriptional regulation. In addition, specialist chapters
cover the role of sumoylation in yeast, viruses and the tumor
suppressor p53. This comprehensive book is the definitive
reference volume on all aspects of sumoylation. It is an
essential reference manual for all researchers interested in
this area.
|
| adam_txt |
Contents
Contents
Contributors
Preface
Chapter
Kirsten
Chapter
Christopher N.
Chapter
Yuan Chen
Chapter
Felicity Watts
Chapter
Andrea Pichler and
Chapter
and De-conjugation Pathways
Hisato Saitoh
Chapter
Yoshiko Kikuchi
Chapter
Valérie
Chapter
Michael J. Matunis
Chapter
David Girdwood, Michael H. Tatham and Ronald T. Hay
Chapter
Germán
Chapter
and of its Ubiquitin
Hideyo Yasuda
Index
iii
SUMOYLATION
MOLECULAR BIOLOGY
AND BIOCHEMISTRY
Sumoylation is a novel post-translational modification system,
biochemically analogous to, but functionally distinct from,
ubiquitinylation. Sumoylation involves the covalent attachment
of a SUMO (small ubiquitin-related modifier) to substrate
proteins. This modification system has crucial roles in many
different biological processes, including protein localization
and stability, transcriptional activities, nucleocytoplasmic
signalling and transport, and genome replication, as well
as the regulation of gene expression. The molecular and
biochemical mechanisms involved in sumoylation have
been the subject of intense interest in recent years. This
volume, edited and written by leading international experts,
is the first book to be devoted to sumoylation. It presents
information on the history, evolution and mechanisms
of sumoylation, discusses SUMO proteases,
conjugation pathways, and reviews the impact on modification
and nucleocytoplasmic transport, PML nuclear bodies and
transcriptional regulation. In addition, specialist chapters
cover the role of sumoylation in yeast, viruses and the tumor
suppressor p53. This comprehensive book is the definitive
reference volume on all aspects of sumoylation. It is an
essential reference manual for all researchers interested in
this area. |
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| index_date | 2024-07-02T14:38:41Z |
| indexdate | 2024-07-09T20:38:55Z |
| institution | BVB |
| isbn | 0954523288 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-014787659 |
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| publisher | Horizon Bioscience |
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| spelling | Sumoylation molecular biology and biochemistry ed. by Van G. Wilson Wymondham Horizon Bioscience 2004 X, 404 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier This volume presents information on the history, evolution and mechanisms of sumoylation, discusses SUMO proteases, ligases and conjugation pathways, and reviews the impact on modification and nucleocytoplasmic transport, PML nuclear bodies, and transcriptional regulation. Specialist chapters cover the role of sumoylation in yeast, viruses and the tumor suppressor p53. Bacterial genetics Extrachromosomal DNA Gene expression Molecular biology Protein Processing, Post-Translational Small Ubiquitin-Related Modifier Proteins metabolism Viral genetics Ubiquitin-ähnliche Proteine (DE-588)4526337-1 gnd rswk-swf Ubiquitin-ähnliche Proteine (DE-588)4526337-1 s b DE-604 Wilson, Van G. Sonstige oth Digitalisierung UBRegensburg application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=014787659&sequence=000003&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis Digitalisierung UB Regensburg application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=014787659&sequence=000004&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA Klappentext |
| spellingShingle | Sumoylation molecular biology and biochemistry Bacterial genetics Extrachromosomal DNA Gene expression Molecular biology Protein Processing, Post-Translational Small Ubiquitin-Related Modifier Proteins metabolism Viral genetics Ubiquitin-ähnliche Proteine (DE-588)4526337-1 gnd |
| subject_GND | (DE-588)4526337-1 |
| title | Sumoylation molecular biology and biochemistry |
| title_auth | Sumoylation molecular biology and biochemistry |
| title_exact_search | Sumoylation molecular biology and biochemistry |
| title_exact_search_txtP | Sumoylation molecular biology and biochemistry |
| title_full | Sumoylation molecular biology and biochemistry ed. by Van G. Wilson |
| title_fullStr | Sumoylation molecular biology and biochemistry ed. by Van G. Wilson |
| title_full_unstemmed | Sumoylation molecular biology and biochemistry ed. by Van G. Wilson |
| title_short | Sumoylation |
| title_sort | sumoylation molecular biology and biochemistry |
| title_sub | molecular biology and biochemistry |
| topic | Bacterial genetics Extrachromosomal DNA Gene expression Molecular biology Protein Processing, Post-Translational Small Ubiquitin-Related Modifier Proteins metabolism Viral genetics Ubiquitin-ähnliche Proteine (DE-588)4526337-1 gnd |
| topic_facet | Bacterial genetics Extrachromosomal DNA Gene expression Molecular biology Protein Processing, Post-Translational Small Ubiquitin-Related Modifier Proteins metabolism Viral genetics Ubiquitin-ähnliche Proteine |
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