Polymeric drug delivery systems:
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
Boca Raton
Taylor & Francis
2005
|
| Schriftenreihe: | Drugs and the pharmaceutical sciences
148 |
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | Includes bibliographical references and index |
| Beschreibung: | xvi, 653 p. ill. 24 cm |
| ISBN: | 0824725328 9780824725327 |
Internformat
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| 490 | 1 | |a Drugs and the pharmaceutical sciences |v 148 | |
| 500 | |a Includes bibliographical references and index | ||
| 650 | 4 | |a Médicaments - Administration - Dispositifs | |
| 650 | 4 | |a Médicaments polymères | |
| 650 | 4 | |a Médicaments polymères - Administration - Dispositifs | |
| 650 | 4 | |a Polymeric drug delivery systems | |
| 650 | 4 | |a Polymeric drugs | |
| 650 | 4 | |a Drug delivery systems | |
| 650 | 4 | |a Polymers |x therapeutic use | |
| 650 | 4 | |a Drug Delivery Systems | |
| 700 | 1 | |a Kwon, Glen S. |e Sonstige |4 oth | |
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Datensatz im Suchindex
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|---|---|
| adam_text | POLYMERIC DRUG DELIVERY SYSTEMS GLEN S. KWON / M / WN / II I IONSIN
TAYLOR &I FRANCIS TD LOR 81 FRANC IS GROUP CONTENTS PREFACE .... IX
CONTRIBUTORS .... XIII 1. ./V-(2-HYDROXYPROPYL)METHACRYLAMIDE COPOLYMER
CONJUGATES 1 RUTH DUNCAN BACKGROUND .... 1 HPMA COPOLYMER CONJUGATES*AN
HISTORICAL PERSPECTIVE .... 5 SYNTHESIS AND CHARACTERIZATION OF HPMA
COPOLYMER CONJUGATES .... 8 BIOLOGICAL RATIONALE FOR DESIGN AND
POTENTIAL APPLICATIONS .... 21 CLINICAL STATUS OF HPMA COPOLYMER
CONJUGATES .... 50 OTHER APPLICATIONS .... 56 RELATED TECHNOLOGIES ....
59 FUTURE PROSPECTS .... 60 J V CONTENTS 2. FUNCTIONAL PEG FOR DRUG
DELIVERY 93 MOTOI OISHI, YUKIO NAGASAKI, AND KAZUNORI KATAOKA
INTRODUCTION .... 93 SYNTHESIS OF HETEROTELECHELIC POLY(ETHYLENE GLYCODS
.... 95 SYNTHESIS OF AN END-FUNCTIONALIZED BLOCK COPOLYMER POSSESSING A
PEG SEGMENT .... 101 BIOCONJUGATION USING HETEROTELECHELIC PEG .... 108
FUNCTIONALIZED POLYMERIC MICELLES BY A SELF-ASSEMBLING OF
END-FUNCTIONALIZED PEG BLOCK COPOLYMERS .... 113 CONCLUSION .... 123 3.
PH-SENSITIVE POLYMERS FOR DRUG DELIVERY KUN NA AND YOU HAN BAE
INTRODUCTION .... 129 P H VARIATION IN THE BODY .... 130 PH-SENSITIVE
POLYMERS .... 133 ORAL DELIVERY .... 135 PARENTERAL D R U G CARRIERS
.... 147 CONCLUSION .... 180 4. HYDROGELS FOR ORAL ADMINISTRATION SEONG
HOON JEONG, YOURONG FU, AND KINAM PARK INTRODUCTION .... 195 APPLICATION
OF HYDROGELS IN ORAL DRUG DELIVERY .... 199 HYDROGELS FOR SPECIFIC
APPLICATIONS .... 208 5. HYDROGELS FOR THE CONTROLLED RELEASE OF
PROTEINS WIM E. HENNINK, CORNELUS F. VAN NOSTRUTN, DAAN J- A. CROMMELIN,
AND JEROEN M. BEZEMER INTRODUCTION .... 215 HYDROGELS: GENERAL FEATURES
.... 216 DEXTRAN HYDROGELS AS PROTEIN-RELEASING MATRICES .... 217
AMPHIPHILIC POLY(ETHER ESTER) MULTIBLOCK COPOLYMERS AS PROTEIN-RELEASING
MATRICES .... 227 CONTENTS V THE STABILITY OF HYDROGEL-ASSOCIATED
PHARMACEUTICAL PROTEINS .... 235 CONCLUDING REMARKS .... 240 6.
THERMOSENSITIVE BIODEGRADABLE HYDROGELS FOR THE DELIVERY OF THERAPEUTIC
AGENTS 251 YOUNG MIN KWON AND SUNG WAN KIM INTRODUCTION .... 251
POLYW-ISOPROPYLACRYL AMIDE) AND ITS COPOLYMERS .... 253 PEO-PPO-PEO
TRIBLOCK COPOLYMERS .... 258 THERMOSENSITIVE AND BIODEGRADABLE POLYMER
HYDROGELS .... 259 BIODEGRADABLE MICROSPHERES BASED ON THE
THERMOSENSITIVE PROPERTY OF PLGA-PEG-PLGA .... 263 CONCLUSIONS .... 269
7. HYDROGELS: STIMULI-SENSITIVE HYDROGELS 275 AKIHIKO KIKUCHI AND TERUO
OKANO INTRODUCTION .... 275 STIMULI-RESPONSIVE HYD2 - OGELS AND THEIR
APPLICATIONS IN DRUG DELIVERY SYSTEMS .... 276 CONCLUSIONS .... 311 8.
TREATMENT OF MALIGNANT BRAIN TUMORS WITH CONTROLLED-RELEASE
LOCAL-DELIVERY POLYMERS . . 323 ALEX A. KHALESSI, PAUL P. WANG. ROBERT
S. LONGER, AND HENRY BRENI INTRODUCTION .... 324 DRUG DELIVERY
CONSIDERATIONS IN THE CXS .... 325 BIOCOMPATIBLE POLYMER DEVELOPMENT: AN
HISTORICAL PERSPECTIVE .... 329 CLINICAL APPLICATIONS OF POLYANHYDRIDO
POLYMERS FOR INTRACRANIAL DRUG DELIVERY .... 333 FUTURE DIRECTIONS ....
359 CONCLUSIONS .... 361 V J CONTENTS 9. IMPROVING THE STABILITY OF
PLGA-ENCAPSULATED PROTEINS STEVEN P. SCHWENDEMAN AND JICHAO KANG
OVERVIEW AND HISTORICAL PERSPECTIVE .... 381 EVIDENCE OF PROTEIN
INSTABILITY .... 382 WHAT IS THE INSTABILITY PATHWAY? .... 383 EXAMPLES
OF STABILIZING PLGA-ENCAPSULATED PROTEINS .... 389 CONCLUDING REMARKS
.... 410 10. RECOMBINANT POLYMERS FOR DRUG DELIVERY ... 417 ZAKI MEGEED
AND HAMIDREZA GHANDEHARI INTRODUCTION .... 417 SYNTHESIS AND
CHARACTERIZATION .... 419 DRUG DELIVERY APPLICATIONS .... 423 GENE
DELIVERY APPLICATIONS .... 435 TISSUE REPAIR APPLICATIONS .... 444
BIOCOMPATIBILITY AND BIODEGRADATION .... 445 CONCLUSIONS .... 447 11.
POLYMERIC NANOPARTICLE DELIVERY OF CANCER VACCINES 455 JOHN SAMUEL AND
GLEN S. KWON INTRODUCTION .... 455 CANCER VACCINES: PROMISE AND PROBLEMS
.... 457 CRITICAL ISSUES IN CANCER VACCINE DELIVERY .... 458 CANCER
VACCINE DELIVERY. LIVING VS. NON-LIVING SYSTEMS .... 463 PLGA-BASED
PHARMACEUTICAL DELIVERY SYSTEMS .... 464 PATHOGEN MIMICKING
NANOPARTICLES FOR CANCER VACCINES .... 465 CONCLUDING REMARKS .... 476
12. POLYMER ASSEMBLIES: INTELLIGENT BLOCK COPOLYMER MICELLES FOR THE
PROGRAMMED DELIVERY OF DRUGS AND GENES 491 YOUNSOO BAE AND KAZUNORI
KATAOKA INTRODUCTION .... 491 RATIONALE FOR DELIVERY SYSTEM USING
POLYMER ASSEMBLIES .... 492 CONTENTS VII BLOCK COPOLYMER MICELLES FOR
DRUG DELIVERY .... 497 BLOCK COPOLYMER MICELLES FOR THE DELIVERY OF
GENES AND CHARGED MATERIALS .... 506 PROGRAMMED DELIVERY USING BLOCK
COPOLYMER MICELLES .... 515 FUTURE PROSPECTS OF BLOCK COPOLYMER MICELLES
.... 524 13. POLYMERIC MICELLES FOR THE TARGETING OF HYDROPHOBIC DRUGS
533 MASAYUKI YOKOYAMA POLYMERIC MICELLES FOR DRUG CARRIERS .... 533 THE
HISTORY OF POLYMERIC MICELLE DRUG CARRIERS .... 543 THE MOLECULAR DESIGN
OF POLYMERIC MICELLE DRUG CARRIER SYSTEMS .... 545 EXAMPLES OF DRUG
TARGETING WITH POLYMERIC MICELLE CARRIERS .... 560 14. PLURONIC K BLOCK
COPOLYMERS FOR DRUG AND GENE DELIVERY .577 ALEXANDER V. KABANOV AND JIAN
ZHU INTRODUCTION .... 577 PLURONIC STRUCTURE AND SYNTHESIS .... 578
SELF-ASSEMBLY OF PLURONIC BLOCK COPOLYMERS .... 580 PLURONIC K
FORMULATIONS FOR TREATMENT OF DRUG-RESISTANT TUMORS .... 581 PLURONIC
EFFECTS ON BRAIN AND ORAL BIOAVAILABILITY OF DRUGS .... 589 OPTIMIZATION
OF PLURONIC COMPOSITION FOR PGP INHIBITION .... 593 PLURONIC BLOCK
COPOLYMERS FOR GENE THERAPY .... 596 15. GRAFT COPOLYMERS FOR
THERAPEUTIC GENE DELIVERY 615 ANN RAG MAHESHIRNRI, JAMES W. YOEKMAN. AND
SUNG WAN KIM NON-VIRAL GENE T H E R A P Y .... 615 VIII CONTENTS
NOMENCLATURE OF GRAFT COPOLYMERS .... 618 CATIONIC GRAFT COPOLYMERS ....
619 BIODEGRADABLE AND TARGETTED POLYMERIC GENE CARRIERS .... 634 INDEX
647
|
| adam_txt |
POLYMERIC DRUG DELIVERY SYSTEMS GLEN S. KWON / M\ / WN / II I\IONSIN
TAYLOR &I FRANCIS TD\LOR 81 FRANC IS GROUP CONTENTS PREFACE . IX
CONTRIBUTORS . XIII 1. ./V-(2-HYDROXYPROPYL)METHACRYLAMIDE COPOLYMER
CONJUGATES 1 RUTH DUNCAN BACKGROUND . 1 HPMA COPOLYMER CONJUGATES*AN
HISTORICAL PERSPECTIVE . 5 SYNTHESIS AND CHARACTERIZATION OF HPMA
COPOLYMER CONJUGATES . 8 BIOLOGICAL RATIONALE FOR DESIGN AND
POTENTIAL APPLICATIONS . 21 CLINICAL STATUS OF HPMA COPOLYMER
CONJUGATES . 50 OTHER APPLICATIONS . 56 RELATED TECHNOLOGIES .
59 FUTURE PROSPECTS . 60 J V CONTENTS 2. FUNCTIONAL PEG FOR DRUG
DELIVERY 93 MOTOI OISHI, YUKIO NAGASAKI, AND KAZUNORI KATAOKA
INTRODUCTION . 93 SYNTHESIS OF HETEROTELECHELIC POLY(ETHYLENE GLYCODS
. 95 SYNTHESIS OF AN END-FUNCTIONALIZED BLOCK COPOLYMER POSSESSING A
PEG SEGMENT . 101 BIOCONJUGATION USING HETEROTELECHELIC PEG . 108
FUNCTIONALIZED POLYMERIC MICELLES BY A SELF-ASSEMBLING OF
END-FUNCTIONALIZED PEG BLOCK COPOLYMERS . 113 CONCLUSION . 123 3.
PH-SENSITIVE POLYMERS FOR DRUG DELIVERY KUN NA AND YOU HAN BAE
INTRODUCTION . 129 P H VARIATION IN THE BODY . 130 PH-SENSITIVE
POLYMERS . 133 ORAL DELIVERY . 135 PARENTERAL D R U G CARRIERS
. 147 CONCLUSION . 180 4. HYDROGELS FOR ORAL ADMINISTRATION SEONG
HOON JEONG, YOURONG FU, AND KINAM PARK INTRODUCTION . 195 APPLICATION
OF HYDROGELS IN ORAL DRUG DELIVERY . 199 HYDROGELS FOR SPECIFIC
APPLICATIONS . 208 5. HYDROGELS FOR THE CONTROLLED RELEASE OF
PROTEINS WIM E. HENNINK, CORNELUS F. VAN NOSTRUTN, DAAN J- A. CROMMELIN,
AND JEROEN M. BEZEMER INTRODUCTION . 215 HYDROGELS: GENERAL FEATURES
. 216 DEXTRAN HYDROGELS AS PROTEIN-RELEASING MATRICES . 217
AMPHIPHILIC POLY(ETHER ESTER) MULTIBLOCK COPOLYMERS AS PROTEIN-RELEASING
MATRICES . 227 CONTENTS V THE STABILITY OF HYDROGEL-ASSOCIATED
PHARMACEUTICAL PROTEINS . 235 CONCLUDING REMARKS . 240 6.
THERMOSENSITIVE BIODEGRADABLE HYDROGELS FOR THE DELIVERY OF THERAPEUTIC
AGENTS 251 YOUNG MIN KWON AND SUNG WAN KIM INTRODUCTION . 251
POLYW-ISOPROPYLACRYL AMIDE) AND ITS COPOLYMERS . 253 PEO-PPO-PEO
TRIBLOCK COPOLYMERS . 258 THERMOSENSITIVE AND BIODEGRADABLE POLYMER
HYDROGELS . 259 BIODEGRADABLE MICROSPHERES BASED ON THE
THERMOSENSITIVE PROPERTY OF PLGA-PEG-PLGA . 263 CONCLUSIONS . 269
7. HYDROGELS: STIMULI-SENSITIVE HYDROGELS 275 AKIHIKO KIKUCHI AND TERUO
OKANO INTRODUCTION . 275 STIMULI-RESPONSIVE HYD2 - OGELS AND THEIR
APPLICATIONS IN DRUG DELIVERY SYSTEMS . 276 CONCLUSIONS . 311 8.
TREATMENT OF MALIGNANT BRAIN TUMORS WITH CONTROLLED-RELEASE
LOCAL-DELIVERY POLYMERS . . 323 ALEX A. KHALESSI, PAUL P. WANG. ROBERT
S. LONGER, AND HENRY BRENI INTRODUCTION . 324 DRUG DELIVERY
CONSIDERATIONS IN THE CXS . 325 BIOCOMPATIBLE POLYMER DEVELOPMENT: AN
HISTORICAL PERSPECTIVE . 329 CLINICAL APPLICATIONS OF POLYANHYDRIDO
POLYMERS FOR INTRACRANIAL DRUG DELIVERY . 333 FUTURE DIRECTIONS .
359 CONCLUSIONS . 361 V J CONTENTS 9. IMPROVING THE STABILITY OF
PLGA-ENCAPSULATED PROTEINS STEVEN P. SCHWENDEMAN AND JICHAO KANG
OVERVIEW AND HISTORICAL PERSPECTIVE . 381 EVIDENCE OF PROTEIN
INSTABILITY . 382 WHAT IS THE INSTABILITY PATHWAY? . 383 EXAMPLES
OF STABILIZING PLGA-ENCAPSULATED PROTEINS . 389 CONCLUDING REMARKS
. 410 10. RECOMBINANT POLYMERS FOR DRUG DELIVERY . 417 ZAKI MEGEED
AND HAMIDREZA GHANDEHARI INTRODUCTION . 417 SYNTHESIS AND
CHARACTERIZATION . 419 DRUG DELIVERY APPLICATIONS . 423 GENE
DELIVERY APPLICATIONS . 435 TISSUE REPAIR APPLICATIONS . 444
BIOCOMPATIBILITY AND BIODEGRADATION . 445 CONCLUSIONS . 447 11.
POLYMERIC NANOPARTICLE DELIVERY OF CANCER VACCINES 455 JOHN SAMUEL AND
GLEN S. KWON INTRODUCTION . 455 CANCER VACCINES: PROMISE AND PROBLEMS
. 457 CRITICAL ISSUES IN CANCER VACCINE DELIVERY . 458 CANCER
VACCINE DELIVERY. LIVING VS. NON-LIVING SYSTEMS . 463 PLGA-BASED
PHARMACEUTICAL DELIVERY SYSTEMS . 464 "PATHOGEN MIMICKING"
NANOPARTICLES FOR CANCER VACCINES . 465 CONCLUDING REMARKS . 476
12. POLYMER ASSEMBLIES: INTELLIGENT BLOCK COPOLYMER MICELLES FOR THE
PROGRAMMED DELIVERY OF DRUGS AND GENES 491 YOUNSOO BAE AND KAZUNORI
KATAOKA INTRODUCTION . 491 RATIONALE FOR DELIVERY SYSTEM USING
POLYMER ASSEMBLIES . 492 CONTENTS VII BLOCK COPOLYMER MICELLES FOR
DRUG DELIVERY . 497 BLOCK COPOLYMER MICELLES FOR THE DELIVERY OF
GENES AND CHARGED MATERIALS . 506 PROGRAMMED DELIVERY USING BLOCK
COPOLYMER MICELLES . 515 FUTURE PROSPECTS OF BLOCK COPOLYMER MICELLES
. 524 13. POLYMERIC MICELLES FOR THE TARGETING OF HYDROPHOBIC DRUGS
533 MASAYUKI YOKOYAMA POLYMERIC MICELLES FOR DRUG CARRIERS . 533 THE
HISTORY OF POLYMERIC MICELLE DRUG CARRIERS . 543 THE MOLECULAR DESIGN
OF POLYMERIC MICELLE DRUG CARRIER SYSTEMS . 545 EXAMPLES OF DRUG
TARGETING WITH POLYMERIC MICELLE CARRIERS . 560 14. PLURONIC K BLOCK
COPOLYMERS FOR DRUG AND GENE DELIVERY .577 ALEXANDER V. KABANOV AND JIAN
ZHU INTRODUCTION . 577 PLURONIC STRUCTURE AND SYNTHESIS . 578
SELF-ASSEMBLY OF PLURONIC BLOCK COPOLYMERS . 580 PLURONIC K
FORMULATIONS FOR TREATMENT OF DRUG-RESISTANT TUMORS . 581 PLURONIC
EFFECTS ON BRAIN AND ORAL BIOAVAILABILITY OF DRUGS . 589 OPTIMIZATION
OF PLURONIC COMPOSITION FOR PGP INHIBITION . 593 PLURONIC BLOCK
COPOLYMERS FOR GENE THERAPY . 596 15. GRAFT COPOLYMERS FOR
THERAPEUTIC GENE DELIVERY 615 ANN RAG MAHESHIRNRI, JAMES W. YOEKMAN. AND
SUNG WAN KIM NON-VIRAL GENE T H E R A P Y . 615 VIII CONTENTS
NOMENCLATURE OF GRAFT COPOLYMERS . 618 CATIONIC GRAFT COPOLYMERS .
619 BIODEGRADABLE AND TARGETTED POLYMERIC GENE CARRIERS . 634 INDEX
647 |
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| id | DE-604.BV021550868 |
| illustrated | Illustrated |
| index_date | 2024-07-02T14:31:33Z |
| indexdate | 2024-07-09T20:38:25Z |
| institution | BVB |
| isbn | 0824725328 9780824725327 |
| language | English |
| lccn | 2005298850 |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-014766939 |
| oclc_num | 60565344 |
| open_access_boolean | |
| owner | DE-19 DE-BY-UBM |
| owner_facet | DE-19 DE-BY-UBM |
| physical | xvi, 653 p. ill. 24 cm |
| publishDate | 2005 |
| publishDateSearch | 2005 |
| publishDateSort | 2005 |
| publisher | Taylor & Francis |
| record_format | marc |
| series | Drugs and the pharmaceutical sciences |
| series2 | Drugs and the pharmaceutical sciences |
| spelling | Polymeric drug delivery systems [edited by] Glen S. Kwon Boca Raton Taylor & Francis 2005 xvi, 653 p. ill. 24 cm txt rdacontent n rdamedia nc rdacarrier Drugs and the pharmaceutical sciences 148 Includes bibliographical references and index Médicaments - Administration - Dispositifs Médicaments polymères Médicaments polymères - Administration - Dispositifs Polymeric drug delivery systems Polymeric drugs Drug delivery systems Polymers therapeutic use Drug Delivery Systems Kwon, Glen S. Sonstige oth Drugs and the pharmaceutical sciences 148 (DE-604)BV000002008 148 GBV Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=014766939&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Polymeric drug delivery systems Drugs and the pharmaceutical sciences Médicaments - Administration - Dispositifs Médicaments polymères Médicaments polymères - Administration - Dispositifs Polymeric drug delivery systems Polymeric drugs Drug delivery systems Polymers therapeutic use Drug Delivery Systems |
| title | Polymeric drug delivery systems |
| title_auth | Polymeric drug delivery systems |
| title_exact_search | Polymeric drug delivery systems |
| title_exact_search_txtP | Polymeric drug delivery systems |
| title_full | Polymeric drug delivery systems [edited by] Glen S. Kwon |
| title_fullStr | Polymeric drug delivery systems [edited by] Glen S. Kwon |
| title_full_unstemmed | Polymeric drug delivery systems [edited by] Glen S. Kwon |
| title_short | Polymeric drug delivery systems |
| title_sort | polymeric drug delivery systems |
| topic | Médicaments - Administration - Dispositifs Médicaments polymères Médicaments polymères - Administration - Dispositifs Polymeric drug delivery systems Polymeric drugs Drug delivery systems Polymers therapeutic use Drug Delivery Systems |
| topic_facet | Médicaments - Administration - Dispositifs Médicaments polymères Médicaments polymères - Administration - Dispositifs Polymeric drug delivery systems Polymeric drugs Drug delivery systems Polymers therapeutic use Drug Delivery Systems |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=014766939&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| volume_link | (DE-604)BV000002008 |
| work_keys_str_mv | AT kwonglens polymericdrugdeliverysystems |