NPY family of peptides in neurobiology, cardiovascular and metabolic disorders: from genes to therapeutics
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
Basel [u.a.]
Birkhäuser
2006
|
| Schriftenreihe: | EXS
95 |
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis Klappentext |
| ISBN: | 3764371552 9783764371555 |
Internformat
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| 245 | 1 | 0 | |a NPY family of peptides in neurobiology, cardiovascular and metabolic disorders |b from genes to therapeutics |c Zofia Zukowska ... eds. |
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Datensatz im Suchindex
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| adam_text | Contents
List of contributors
Introduction
Zofia Zukowska and Giora Z.
NPY family of peptides in neurobiology, cardiovascular
system and metabolism: genes, diseases and therapeutics
NPY family of peptides, receptors and processing enzymes
Yvan Dumont and
An overview of neuropeptide Y: pharmacology to molecular
biology and receptor localization
Nicole Merten and Annette G. Beck-Sickinger
Molecular ligand-receptor interaction of the NPY/PP peptide family
Physiological and pathophy siological perspectives of the NPY family of
peptides
M. Veronica
Modulator role of neuropeptide
neuroeffector junctions
Danielle Jacques, Sawsan Sader,
Dima
NPY and NPY receptors: presence, distribution and roles in the
regulation of the endocardial endothelium and cardiac function
Thomas C.
Neuropeptide
hypertension
Lars Edvinsson
Neuropeptide
Giora Z.
Neuropeptide
infarction and heart failure
VI
Joseph Winaver and Zaid Abassi
Role of
L. Christine Turtzo and M. Daniel Lane
NPY and neuron-adipocyte interactions in the regulation
of metabolism
Douglas J. MacNeil andAkio Kanatani
NPY and energy homeostasis: an opportunity for novel
anti-obesity therapies
Satya P. Kalra and Pushpa S. Kalra
Subjugation of hypothalamic NPY and cohorts with central
leptin gene therapy alleviates dyslipidemia, insulin resistance,
and obesity for life-time
Susan J. Allison and Herbert
NPY and bone
Annika Thorseil,
NPY in alcoholism and psychiatric disorders
Helen E. Scharfman and William P. Gray
Plasticity of neuropeptide
and its relevance to seizure-induced neurogenesis
Mary Ann Dutton, Edward W. Lee, and Zofia Zukowska
NPY and extreme stress: lessons learned from posttraumatic
stress disorder
Carol A. Colton and Michael P. Vitek
NPY and chronic
Genetics of the NPY family of peptides and their receptors
Ullamari Pesonen
Human NPY gene variants in cardiovascular and metabolic diseases
Summary
Zofia Zukowska and Giora Z.
Future directions and perspectives for therapies based on the
NPY family of peptides
Index
NPY Family of Peptides in Neurobiology, Cardiovascular
and Metabolic Disorders: from Genes to Therapeutics
Zofia Zukowska, Giora Z.
The NPY-family of peptides encompasses several groups of neuro-
transmitters and hormones, which exert diverse biological and patho¬
logical actions that bear on all major vital systems. This book is a
unique compilation of the most recent breakthroughs in NPY/PYY
neurobiology, cardiovascular and metabolic disorders. The identifica¬
tion of multiple receptors for the members of the NPY and PYY fam¬
ily of peptides provides new opportunities for discovery of specific
NPY antagonists and agonists that have vast clinical potential. The
recognition of the role of NPY in stimulation of food intake has
already resulted in discovery of potent and selective NPY receptor
Y-5 antagonists, which are in clinical development for obesity.
NPY Yl receptor antagonists are targeted for cardiovascular indica¬
tions. Research into the multiple functions of NPY and its receptors
in neurological and affective disorders is also actively pursued.
The chapters in this book are written by internationally renowned
experts with the objective to synthesize leading concepts and data in
support for translational medicine.
The ideal complement to this volume is the book NPY Family of
Peptides in Immune Disorders, Inflammation, Angiogenesis, and
Cancer, recently published by the same editors in the
series Progress in Inflammation Research. Both volumes together give
a comprehensive overview of the NPY family of peptides.
|
| adam_txt |
Contents
List of contributors
Introduction
Zofia Zukowska and Giora Z.
NPY family of peptides in neurobiology, cardiovascular
system and metabolism: genes, diseases and therapeutics
NPY family of peptides, receptors and processing enzymes
Yvan Dumont and
An overview of neuropeptide Y: pharmacology to molecular
biology and receptor localization
Nicole Merten and Annette G. Beck-Sickinger
Molecular ligand-receptor interaction of the NPY/PP peptide family
Physiological and pathophy siological perspectives of the NPY family of
peptides
M. Veronica
Modulator role of neuropeptide
neuroeffector junctions
Danielle Jacques, Sawsan Sader,
Dima
NPY and NPY receptors: presence, distribution and roles in the
regulation of the endocardial endothelium and cardiac function
Thomas C.
Neuropeptide
hypertension
Lars Edvinsson
Neuropeptide
Giora Z.
Neuropeptide
infarction and heart failure
VI
Joseph Winaver and Zaid Abassi
Role of
L. Christine Turtzo and M. Daniel Lane
NPY and neuron-adipocyte interactions in the regulation
of metabolism
Douglas J. MacNeil andAkio Kanatani
NPY and energy homeostasis: an opportunity for novel
anti-obesity therapies
Satya P. Kalra and Pushpa S. Kalra
Subjugation of hypothalamic NPY and cohorts with central
leptin gene therapy alleviates dyslipidemia, insulin resistance,
and obesity for life-time
Susan J. Allison and Herbert
NPY and bone
Annika Thorseil,
NPY in alcoholism and psychiatric disorders
Helen E. Scharfman and William P. Gray
Plasticity of neuropeptide
and its relevance to seizure-induced neurogenesis
Mary Ann Dutton, Edward W. Lee, and Zofia Zukowska
NPY and extreme stress: lessons learned from posttraumatic
stress disorder
Carol A. Colton and Michael P. Vitek
NPY and chronic
Genetics of the NPY family of peptides and their receptors
Ullamari Pesonen
Human NPY gene variants in cardiovascular and metabolic diseases
Summary
Zofia Zukowska and Giora Z.
Future directions and perspectives for therapies based on the
NPY family of peptides
Index
NPY Family of Peptides in Neurobiology, Cardiovascular
and Metabolic Disorders: from Genes to Therapeutics
Zofia Zukowska, Giora Z.
The NPY-family of peptides encompasses several groups of neuro-
transmitters and hormones, which exert diverse biological and patho¬
logical actions that bear on all major vital systems. This book is a
unique compilation of the most recent breakthroughs in NPY/PYY
neurobiology, cardiovascular and metabolic disorders. The identifica¬
tion of multiple receptors for the members of the NPY and PYY fam¬
ily of peptides provides new opportunities for discovery of specific
NPY antagonists and agonists that have vast clinical potential. The
recognition of the role of NPY in stimulation of food intake has
already resulted in discovery of potent and selective NPY receptor
Y-5 antagonists, which are in clinical development for obesity.
NPY Yl receptor antagonists are targeted for cardiovascular indica¬
tions. Research into the multiple functions of NPY and its receptors
in neurological and affective disorders is also actively pursued.
The chapters in this book are written by internationally renowned
experts with the objective to synthesize leading concepts and data in
support for translational medicine.
The ideal complement to this volume is the book NPY Family of
Peptides in Immune Disorders, Inflammation, Angiogenesis, and
Cancer, recently published by the same editors in the
series Progress in Inflammation Research. Both volumes together give
a comprehensive overview of the NPY family of peptides. |
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| spelling | NPY family of peptides in neurobiology, cardiovascular and metabolic disorders from genes to therapeutics Zofia Zukowska ... eds. Basel [u.a.] Birkhäuser 2006 txt rdacontent n rdamedia nc rdacarrier EXS 95 Hormones gastro-intestinales - Physiopathologie Neuropeptide Y - Dérivés - Physiopathologie Neuropeptide Y - Physiopathologie Gastrointestinal hormones Pathophysiology Neuropeptide Y Neuropeptide Y Derivatives Pathophysiology Neuropeptide Y Pathophysiology Neuropeptid Y (DE-588)4317370-6 gnd rswk-swf Pathophysiologie (DE-588)4044898-8 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Neuropeptid Y (DE-588)4317370-6 s Pathophysiologie (DE-588)4044898-8 s DE-604 Zukowska, Zofia Sonstige (DE-588)130488704 oth EXS 95 (DE-604)BV006943917 95 Digitalisierung UBRegensburg application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=014753189&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis Digitalisierung UB Regensburg application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=014753189&sequence=000002&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA Klappentext |
| spellingShingle | NPY family of peptides in neurobiology, cardiovascular and metabolic disorders from genes to therapeutics EXS Hormones gastro-intestinales - Physiopathologie Neuropeptide Y - Dérivés - Physiopathologie Neuropeptide Y - Physiopathologie Gastrointestinal hormones Pathophysiology Neuropeptide Y Neuropeptide Y Derivatives Pathophysiology Neuropeptide Y Pathophysiology Neuropeptid Y (DE-588)4317370-6 gnd Pathophysiologie (DE-588)4044898-8 gnd |
| subject_GND | (DE-588)4317370-6 (DE-588)4044898-8 (DE-588)4143413-4 |
| title | NPY family of peptides in neurobiology, cardiovascular and metabolic disorders from genes to therapeutics |
| title_auth | NPY family of peptides in neurobiology, cardiovascular and metabolic disorders from genes to therapeutics |
| title_exact_search | NPY family of peptides in neurobiology, cardiovascular and metabolic disorders from genes to therapeutics |
| title_exact_search_txtP | NPY family of peptides in neurobiology, cardiovascular and metabolic disorders from genes to therapeutics |
| title_full | NPY family of peptides in neurobiology, cardiovascular and metabolic disorders from genes to therapeutics Zofia Zukowska ... eds. |
| title_fullStr | NPY family of peptides in neurobiology, cardiovascular and metabolic disorders from genes to therapeutics Zofia Zukowska ... eds. |
| title_full_unstemmed | NPY family of peptides in neurobiology, cardiovascular and metabolic disorders from genes to therapeutics Zofia Zukowska ... eds. |
| title_short | NPY family of peptides in neurobiology, cardiovascular and metabolic disorders |
| title_sort | npy family of peptides in neurobiology cardiovascular and metabolic disorders from genes to therapeutics |
| title_sub | from genes to therapeutics |
| topic | Hormones gastro-intestinales - Physiopathologie Neuropeptide Y - Dérivés - Physiopathologie Neuropeptide Y - Physiopathologie Gastrointestinal hormones Pathophysiology Neuropeptide Y Neuropeptide Y Derivatives Pathophysiology Neuropeptide Y Pathophysiology Neuropeptid Y (DE-588)4317370-6 gnd Pathophysiologie (DE-588)4044898-8 gnd |
| topic_facet | Hormones gastro-intestinales - Physiopathologie Neuropeptide Y - Dérivés - Physiopathologie Neuropeptide Y - Physiopathologie Gastrointestinal hormones Pathophysiology Neuropeptide Y Neuropeptide Y Derivatives Pathophysiology Neuropeptide Y Pathophysiology Neuropeptid Y Pathophysiologie Aufsatzsammlung |
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