Evaluation of the StratusOCT in the diagnosis of Glaucoma in a modern glaucoma clinic:
Gespeichert in:
| 1. Verfasser: | |
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| Format: | Buch |
| Sprache: | English |
| Veröffentlicht: |
2006
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| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | Regensburg, Univ., Diss., 2006 |
| Beschreibung: | 57 Bl. Ill., graph. Darst. |
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| 245 | 1 | 0 | |a Evaluation of the StratusOCT in the diagnosis of Glaucoma in a modern glaucoma clinic |c presented by Amir AlyEldin Hassan Abousamra |
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| adam_text | Table of Contents
Subject Page
Introduction 1
• Standard ONH Evaluation 3
• ONH Imaging Analysis 3
• RNFL Analysis 3
• OCT 4
Aim of the Work 6
Subjects and Methods 7
• Design of the Study 7
• Subjects and Methods 7
• Imaging Acquisition, processing and interpretation 9
o Fundus Photo 9
o OCT scan 9
¦ Fast Optic Disc Scan Protocol 9
¦ RNFL Thickness (3.4) Scan protocol of the ONH 10
o CSLO (HRT) Image Acquisition 14
Results 15
• Statistical Analysis 15
• The Demographic and Clinical characteristics 15
• The RNFL Thickness and its distribution 17
• OCT ONH parameters 17
• HRT ONH parameters 17
Discussion 23
• Introduction 23
• TheOCT 24
o Reproducibility and Reliability in Glaucoma diagnosis 24
o Sensitivity and Specificity in Glaucoma 26
o Ability to detect change in Glaucoma 28
o Comparison with other instruments used in glaucoma diagnosis 28
o StrarusOCTvs Older versions 31
o Advantage of the OCT in glaucoma 32
o Disadvantage of the OCT in glaucoma 32
• ONH Parameters 33
o Normal ONH Parameters 33
¦ Ethnic Group and Cup Area 33
¦ Age 34
¦ Sex 34
• Laterality 34
¦ Refractive Error 34
o Optic Disc Size in Glaucoma 35
o Ability of the ONH parameters to differentiate different forms of glaucoma 35
o Evaluation of the Fast Optic disc program 36
• RNFL 41
o RNFL Thickness 41
o Evaluation of the RNFLT program 41
• Self Criticism 49
• Conclusion 50
• Acknowledgement 50
References 51
List of Figures
Fig. No. I Description I F«ge
Fig.1 The RNFL Thickness Scan (3.4) mm using the StratusOCT software version 4. 13
Fig. 2 The Fast Optic Disc Head Analysis Scan using me StratusOCT software version 4. 13
Fig. 3 The box plot curve of the BCVA (left) and the SE (right) among GL, GS and N 13
groups.
Fig. 4 The Box Plot curve of the MD (left) and PSD (right) among GL, GS and N. It
Fig. 5 The Box Plot curve of the mean IOP (left) among GL, GS and N and the Box Plot 17
curve of the CCT (Right) among GL, GS.
Fig. 6 Bar chart presentation of the clock hour distribution of the RNFL in GL, GS and N IS
with the classical RNFL bi humped appearance.
Fig.7 The quadrantic distribution of the RNFL in GL, GS and N. 19
Fig. 8 RNFL (Avg and Mean) in GL.GS and N. 20
Fig. 9 The Bar Chart presentation ofmeONH parameters measured by the OCT in the GL, 21
GS and N groups.
Fig. 10 Comparison between the HRT ONH parameter s Mean in GL, GS and N. 22
Fig. 11 The discrepancy between a smaller sized OCT and the normal disc as seen by a 31
colored tundus photo.
Fig. 12 The discrepancy between an abnormally horizontally elongated OCT and the normal 31
disc as seen by a colored fandus photo.
Fig. 13 The failure of the automated program of the StratusOCT to exclude the peripapillary 31
atrophy.
Fig. 14 Pearson correlation between the CDR HRT and the CDR OCT in GL group. 40
Fig. 15 the Box Plot representation of the CDR obtained by the HRT and the OCT in the 40
GL group.
Fig. 16 The discrepancy between the 2 eyes RNFLT obtained by the OCT in a patient with 43
asymmetrical COAG.
Fig. 17 OCT scans for the RNFL utilizing the same 3.4 radius mm in the same patient taken 44
within 2 months.
Fig. 18 The discrepancy between the RNFL measurements in the same eye within 2 months 45
Fig. 19 Showing the discrepancy in RNFL measurement of the same patient, when he was 4*
examined within 2 weeks period.
Fig. 20 a 3.4 scan circle that is shifted inferonasal 47
Fig. 21 I Failure of the OCT to detect the RNFL correctly. I 48
List of Tables
Table No. I Description I Page
Table 1 The Demographic and clinical characteristics of the participants. 15
Table 2 The Mean and standard deviation clock hour values for the RNFL for GL, GS and 18
_R
Table 3 The Mean and standard deviation of Superior, Temporal Inferior and nasal 19
quadrants RNFL values for GL, GS and N.
Table 4 The ONH different parameters obtained by the OCT in the GL, GS and N groups. 21
Table 5 Mean values of optic disc topographic parameters obtained by the HRT II 22
instrument.
Table 6 Showing the Significant difference between the non selected OCT photos and 39
HRT when Disc Area measurements were taken by both instruments in the GL
group (paired i test).
Table 7 The non Significant difference between the selected 10 good quality OCT photos 39
and the HRT Disc Area measurements using the paired t test.
Table S the Non significant difference between the CDR in the 10 selected cases of the 39
GL group when measured by the OCT and HRT by using the paired t test
Table 9 | The SD, Mean ofthe CDR obtained by HRT and OCT in the GL group. I 40
|
| adam_txt |
Table of Contents
Subject Page
Introduction 1
• Standard ONH Evaluation 3
• ONH Imaging Analysis 3
• RNFL Analysis 3
• OCT 4
Aim of the Work 6
Subjects and Methods 7
• Design of the Study 7
• Subjects and Methods 7
• Imaging Acquisition, processing and interpretation 9
o Fundus Photo 9
o OCT scan 9
¦ Fast Optic Disc Scan Protocol 9
¦ RNFL Thickness (3.4) Scan protocol of the ONH 10
o CSLO (HRT) Image Acquisition 14
Results 15
• Statistical Analysis 15
• The Demographic and Clinical characteristics 15
• The RNFL Thickness and its distribution 17
• OCT ONH parameters 17
• HRT ONH parameters 17
Discussion 23
• Introduction 23
• TheOCT 24
o Reproducibility and Reliability in Glaucoma diagnosis 24
o Sensitivity and Specificity in Glaucoma 26
o Ability to detect change in Glaucoma 28
o Comparison with other instruments used in glaucoma diagnosis 28
o StrarusOCTvs Older versions 31
o Advantage of the OCT in glaucoma 32
o Disadvantage of the OCT in glaucoma 32
• ONH Parameters 33
o Normal ONH Parameters 33
¦ Ethnic Group and Cup Area 33
¦ Age 34
¦ Sex 34
• Laterality 34
¦ Refractive Error 34
o Optic Disc Size in Glaucoma 35
o Ability of the ONH parameters to differentiate different forms of glaucoma 35
o Evaluation of the Fast Optic disc program 36
• RNFL 41
o RNFL Thickness 41
o Evaluation of the RNFLT program 41
• Self Criticism 49
• Conclusion 50
• Acknowledgement 50
References 51
List of Figures
Fig. No. I Description I F«ge
Fig.1 The RNFL Thickness Scan (3.4) mm using the StratusOCT software version 4. 13
Fig. 2 The Fast Optic Disc Head Analysis Scan using me StratusOCT software version 4. 13
Fig. 3 The box plot curve of the BCVA (left) and the SE (right) among GL, GS and N 13
groups.
Fig. 4 The Box Plot curve of the MD (left) and PSD (right) among GL, GS and N. It
Fig. 5 The Box Plot curve of the mean IOP (left) among GL, GS and N and the Box Plot 17
curve of the CCT (Right) among GL, GS.
Fig. 6 Bar chart presentation of the clock hour distribution of the RNFL in GL, GS and N IS
with the classical RNFL bi humped appearance.
Fig.7 The quadrantic distribution of the RNFL in GL, GS and N. 19
Fig. 8 RNFL (Avg and Mean) in GL.GS and N. 20
Fig. 9 The Bar Chart presentation ofmeONH parameters measured by the OCT in the GL, 21
GS and N groups.
Fig. 10 Comparison between the HRT ONH parameter's Mean in GL, GS and N. 22
Fig. 11 The discrepancy between a smaller sized OCT and the normal disc as seen by a 31
colored tundus photo.
Fig. 12 The discrepancy between an abnormally horizontally elongated OCT and the normal 31
disc as seen by a colored fandus photo.
Fig. 13 The failure of the automated program of the StratusOCT to exclude the peripapillary 31
atrophy.
Fig. 14 Pearson correlation between the CDR HRT and the CDR OCT in GL group. 40
Fig. 15 the Box Plot representation of the CDR obtained by the HRT and the OCT in the 40
GL group.
Fig. 16 The discrepancy between the 2 eyes RNFLT obtained by the OCT in a patient with 43
asymmetrical COAG.
Fig. 17 OCT scans for the RNFL utilizing the same 3.4 radius mm in the same patient taken 44
within 2 months.
Fig. 18 The discrepancy between the RNFL measurements in the same eye within 2 months 45
Fig. 19 Showing the discrepancy in RNFL measurement of the same patient, when he was 4*
examined within 2 weeks period.
Fig. 20 a 3.4 scan circle that is shifted inferonasal 47
Fig. 21 I Failure of the OCT to detect the RNFL correctly. I 48
List of Tables
Table No. I Description I Page
Table 1 The Demographic and clinical characteristics of the participants. 15
Table 2 The Mean and standard deviation clock hour values for the RNFL for GL, GS and 18
_R
Table 3 The Mean and standard deviation of Superior, Temporal Inferior and nasal 19
quadrants' RNFL values for GL, GS and N.
Table 4 The ONH different parameters obtained by the OCT in the GL, GS and N groups. 21
Table 5 Mean values of optic disc topographic parameters obtained by the HRT II 22
instrument.
Table 6 Showing the Significant difference between the non selected OCT photos and 39
HRT when Disc Area measurements were taken by both instruments in the GL
group (paired i test).
Table 7 The non Significant difference between the selected 10 good quality OCT photos 39
and the HRT Disc Area measurements using the paired t test.
Table S the Non significant difference between the CDR in the 10 selected cases of the 39
GL group when measured by the OCT and HRT by using the paired t test
Table 9 | The SD, Mean ofthe CDR obtained by HRT and OCT in the GL group. I 40 |
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| spelling | Abousamra, Amir AlyEldin Hassan Verfasser aut Evaluation of the StratusOCT in the diagnosis of Glaucoma in a modern glaucoma clinic presented by Amir AlyEldin Hassan Abousamra 2006 57 Bl. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Regensburg, Univ., Diss., 2006 Diagnose (DE-588)4012040-5 gnd rswk-swf Tomogramm (DE-588)4185643-0 gnd rswk-swf Glaukom (DE-588)4021210-5 gnd rswk-swf (DE-588)4113937-9 Hochschulschrift gnd-content Glaukom (DE-588)4021210-5 s Diagnose (DE-588)4012040-5 s Tomogramm (DE-588)4185643-0 s b DE-604 HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=014728250&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Abousamra, Amir AlyEldin Hassan Evaluation of the StratusOCT in the diagnosis of Glaucoma in a modern glaucoma clinic Diagnose (DE-588)4012040-5 gnd Tomogramm (DE-588)4185643-0 gnd Glaukom (DE-588)4021210-5 gnd |
| subject_GND | (DE-588)4012040-5 (DE-588)4185643-0 (DE-588)4021210-5 (DE-588)4113937-9 |
| title | Evaluation of the StratusOCT in the diagnosis of Glaucoma in a modern glaucoma clinic |
| title_auth | Evaluation of the StratusOCT in the diagnosis of Glaucoma in a modern glaucoma clinic |
| title_exact_search | Evaluation of the StratusOCT in the diagnosis of Glaucoma in a modern glaucoma clinic |
| title_exact_search_txtP | Evaluation of the StratusOCT in the diagnosis of Glaucoma in a modern glaucoma clinic |
| title_full | Evaluation of the StratusOCT in the diagnosis of Glaucoma in a modern glaucoma clinic presented by Amir AlyEldin Hassan Abousamra |
| title_fullStr | Evaluation of the StratusOCT in the diagnosis of Glaucoma in a modern glaucoma clinic presented by Amir AlyEldin Hassan Abousamra |
| title_full_unstemmed | Evaluation of the StratusOCT in the diagnosis of Glaucoma in a modern glaucoma clinic presented by Amir AlyEldin Hassan Abousamra |
| title_short | Evaluation of the StratusOCT in the diagnosis of Glaucoma in a modern glaucoma clinic |
| title_sort | evaluation of the stratusoct in the diagnosis of glaucoma in a modern glaucoma clinic |
| topic | Diagnose (DE-588)4012040-5 gnd Tomogramm (DE-588)4185643-0 gnd Glaukom (DE-588)4021210-5 gnd |
| topic_facet | Diagnose Tomogramm Glaukom Hochschulschrift |
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