Long-term psychobiological consequences of adverse childhood experiences: implications for vulnerability and resilience
Gespeichert in:
1. Verfasser: | |
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Format: | Abschlussarbeit Buch |
Sprache: | English |
Veröffentlicht: |
Göttingen
Cuvillier
2005
|
Ausgabe: | 1. Aufl. |
Schlagworte: | |
Online-Zugang: | Inhaltsverzeichnis |
Beschreibung: | XIV, 181 S. graph. Darst. |
ISBN: | 3865375863 |
Internformat
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Datensatz im Suchindex
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adam_text | Titel: Long-term psychobiological consequences of adverse childhood experiences
Autor: Meinlschmidt, Gunther Pascal
Jahr: 2005
____ Table of Contents
Table of Contents
Acknowledgments Ill
Table of Contents V
Abbreviations IX
Index of Tables and Figures ...XII
1 Introduction and Objectives 1
1.1 Introduction . ,., ,2
1.2 Scope of the Thesis 5
1.2.1 Objectives 5
1.2.2 Hypotheses 5
1.2.3 Approach 6
1.3 Outline of the Thesis 7
2 Theoretical Background 9
2.1 Overview of Major Types of Adverse Childhood Experiences.. 10
2.2 Adverse Childhood Experiences in Form of Sexual Violence, Physical
Violence, and Parental Loss 11
2.3 Adverse Childhood Experiences and Vulnerability to Mental Disorders and
Physical Illnesses 12
2.4 Adverse Childhood Experiences and Resilience to Mental Disorders and
Physical Illnesses 13
2.5 Biological Consequences of Adverse Childhood Experiences ..14
2.6 Theoretical Models of Long-Term Consequences of Early Experiences 18
3 Pituitary-Adrenal Responses to Physical Exercise in Women with
Adverse Chadhood Experiences ...27
3.1 Preface. - 28
3.2 Abstract 29
3.3 Introduction.. - 30
3.4 Material and Methods .....33
3.4.1 Participants.. • 33
3.4.2 Psychiatric and ACE Assessment.... 33
V
Table of Contents I
3.4.3 Physical Stress Test 34
3.4.4 Laboratory Assays ¦
3.4.5 Statistical Analysis 3^
3.5 Results 36
3.5.1 Study Participants and Exercise Test 36
3.53 Neuroendocrine Data 38
3.6 Discussion • ....44
4 Pituitary Responses in the Arginine Vasopressin Stimulation Test
in Women with Adverse Childhood Experiences 51
4.1 Preface 52
4.2 Abstract 53
4.3 Introduction 54
4.4 Material and Methods 56
4.4.1 Participants ; 56
4.4.2 Psychiatric, ACE, and Chronic Stress Assessment 56
4.4.3 Arginine Vasopressin Stimulation Test 57
4.4.4 Laboratory Assays 58
4.4.5 Statistical Analysis 60
4.5 Results ; 60
4.5.1 Study Participants , 60 :
4.5.2 Neuroendocrine Data 63
4.5.2.1 Between-Group Comparisons 63
4.5.2.2 Multiple Regression Analyses 63 i
4.6 Discussion 68 j
j
S First Evidence for Altered Female Sex Hormone Effects on Adreno- i
corticotropin Secretion in Women with Adverse Childhood Experiences 73 I
5.1 Preface.. 74
5.2 Abstract , 75
5.3 Introduction ,,,.., 76
5.4 Material and Methods., 80
5.4.1 Participants.. go
5.4.2 Psychiatric, ACE, and Chronic Stress Assessment... 81
VI
_____ Table of Contents
5.4.3 Arginine Vasopressin Stimulation Test 81
5.4.4 Laboratory Assays 82
5.4.5 Statistical Analysis 82
5.5 Results 84
5.5.1 Study Participants 84
5.5.2 Neuroendocrine Data 87
5.6 Discussion 92
6 Sensitivity to Intranasal Oxytocin in Adult Men After Early Parental
Separation......... 101
6.1 Preface ..102
6.2 Abstract 104
6.3 Introduction 105
6.4 Material and Methods ....107
6.4.1 Participants and Their Psychological and Biographical Assessment 107
6.4.2 Oxytocin Application and Laboratory Assays ^....107
6.4.3 Statistical Analysis 107
6.5 Results 108
6.6 Discussion Ill
7 Summary and Main Conclusions ......113
7.1 Hypothesis One 114
7.2 Hypothesis Two 114
7.3 Hypothesis Three 115
7.4 Hypothesis Four 116
8 General Discussion....... ••-.•. 117
8.1 General limitations of the Studies 118
8.2 Implications for Biological Models of Long-Term Consequences
of Adverse Childhood Experiences 122
8.3 Implications for Theoretical Models of Long-Term Consequences
of Adverse Childhood Experiences, , 129
8.4 Implications for Vulnerability and Resilience .136
VH
I
Table of Contents
9 Outlook 141
9.1 Future Research Directions 142
9.2 Future Diagnostic Directions 146
9.3 Future Directions for Prevention and Treatment., 147
Abstract in English 151
Abstract in German / Zusammenfassung 153
References 155
j
i
vm
|
adam_txt |
Titel: Long-term psychobiological consequences of adverse childhood experiences
Autor: Meinlschmidt, Gunther Pascal
Jahr: 2005
_ Table of Contents
Table of Contents
Acknowledgments Ill
Table of Contents V
Abbreviations IX
Index of Tables and Figures .XII
1 Introduction and Objectives 1
1.1 Introduction . ,., ,2
1.2 Scope of the Thesis 5
1.2.1 Objectives 5
1.2.2 Hypotheses 5
1.2.3 Approach 6
1.3 Outline of the Thesis 7
2 Theoretical Background 9
2.1 Overview of Major Types of Adverse Childhood Experiences. 10
2.2 Adverse Childhood Experiences in Form of Sexual Violence, Physical
Violence, and Parental Loss 11
2.3 Adverse Childhood Experiences and Vulnerability to Mental Disorders and
Physical Illnesses 12
2.4 Adverse Childhood Experiences and Resilience to Mental Disorders and
Physical Illnesses 13
2.5 Biological Consequences of Adverse Childhood Experiences .14
2.6 Theoretical Models of Long-Term Consequences of Early Experiences 18
3 Pituitary-Adrenal Responses to Physical Exercise in Women with
Adverse Chadhood Experiences .27
3.1 Preface. - 28
3.2 Abstract 29
3.3 Introduction. - 30
3.4 Material and Methods .33
3.4.1 Participants. • 33
3.4.2 Psychiatric and ACE Assessment. 33
V
Table of Contents I
3.4.3 Physical Stress Test 34
3.4.4 Laboratory Assays ¦"
3.4.5 Statistical Analysis 3^
3.5 Results 36
3.5.1 Study Participants and Exercise Test 36
3.53 Neuroendocrine Data 38
3.6 Discussion • .44
4 Pituitary Responses in the Arginine Vasopressin Stimulation Test
in Women with Adverse Childhood Experiences 51
4.1 Preface 52
4.2 Abstract 53
4.3 Introduction 54
4.4 Material and Methods 56
4.4.1 Participants ; 56
4.4.2 Psychiatric, ACE, and Chronic Stress Assessment 56
4.4.3 Arginine Vasopressin Stimulation Test 57
4.4.4 Laboratory Assays 58
4.4.5 Statistical Analysis 60
4.5 Results ; 60
4.5.1 Study Participants , 60 :
4.5.2 Neuroendocrine Data 63
4.5.2.1 Between-Group Comparisons 63
4.5.2.2 Multiple Regression Analyses 63 i
4.6 Discussion 68 j
j
S First Evidence for Altered Female Sex Hormone Effects on Adreno- i
corticotropin Secretion in Women with Adverse Childhood Experiences 73 I
5.1 Preface. 74
5.2 Abstract , 75
5.3 Introduction ,,,., 76
5.4 Material and Methods., 80
5.4.1 Participants. go
5.4.2 Psychiatric, ACE, and Chronic Stress Assessment. 81
VI
_ Table of Contents
5.4.3 Arginine Vasopressin Stimulation Test 81
5.4.4 Laboratory Assays 82
5.4.5 Statistical Analysis 82
5.5 Results 84
5.5.1 Study Participants 84
5.5.2 Neuroendocrine Data 87
5.6 Discussion 92
6 Sensitivity to Intranasal Oxytocin in Adult Men After Early Parental
Separation. 101
6.1 Preface .102
6.2 Abstract 104
6.3 Introduction 105
6.4 Material and Methods .107
6.4.1 Participants and Their Psychological and Biographical Assessment 107
6.4.2 Oxytocin Application and Laboratory Assays ^.107
6.4.3 Statistical Analysis 107
6.5 Results 108
6.6 Discussion Ill
7 Summary and Main Conclusions .113
7.1 Hypothesis One 114
7.2 Hypothesis Two 114
7.3 Hypothesis Three 115
7.4 Hypothesis Four 116
8 General Discussion. ••-.•. 117
8.1 General limitations of the Studies 118
8.2 Implications for Biological Models of Long-Term Consequences
of Adverse Childhood Experiences 122
8.3 Implications for Theoretical Models of Long-Term Consequences
of Adverse Childhood Experiences, , 129
8.4 Implications for Vulnerability and Resilience .136
VH
I
Table of Contents
9 Outlook 141
9.1 Future Research Directions 142
9.2 Future Diagnostic Directions 146
9.3 Future Directions for Prevention and Treatment., 147
Abstract in English 151
Abstract in German / Zusammenfassung 153
References 155
j
i
vm |
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any_adam_object_boolean | 1 |
author | Meinlschmidt, Gunther 1974- |
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author_sort | Meinlschmidt, Gunther 1974- |
author_variant | g m gm |
building | Verbundindex |
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ctrlnum | (OCoLC)76873407 (DE-599)BVBBV021489335 |
dewey-full | 150 |
dewey-hundreds | 100 - Philosophy & psychology |
dewey-ones | 150 - Psychology |
dewey-raw | 150 |
dewey-search | 150 |
dewey-sort | 3150 |
dewey-tens | 150 - Psychology |
discipline | Psychologie Medizin |
discipline_str_mv | Psychologie Medizin |
edition | 1. Aufl. |
format | Thesis Book |
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spelling | Meinlschmidt, Gunther 1974- Verfasser (DE-588)173791964 aut Long-term psychobiological consequences of adverse childhood experiences implications for vulnerability and resilience Gunther Pascal Meinlschmidt 1. Aufl. Göttingen Cuvillier 2005 XIV, 181 S. graph. Darst. txt rdacontent n rdamedia nc rdacarrier Zugl.: Trier, Univ., Diss., 2005 Psychisches Trauma (DE-588)4060749-5 gnd rswk-swf Neuroendokrines System (DE-588)4128912-2 gnd rswk-swf Regulationsstörung (DE-588)4678063-4 gnd rswk-swf Kindheitserinnerung (DE-588)4163872-4 gnd rswk-swf (DE-588)4113937-9 Hochschulschrift gnd-content Kindheitserinnerung (DE-588)4163872-4 s Psychisches Trauma (DE-588)4060749-5 s Neuroendokrines System (DE-588)4128912-2 s Regulationsstörung (DE-588)4678063-4 s DE-604 HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=014706189&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
spellingShingle | Meinlschmidt, Gunther 1974- Long-term psychobiological consequences of adverse childhood experiences implications for vulnerability and resilience Psychisches Trauma (DE-588)4060749-5 gnd Neuroendokrines System (DE-588)4128912-2 gnd Regulationsstörung (DE-588)4678063-4 gnd Kindheitserinnerung (DE-588)4163872-4 gnd |
subject_GND | (DE-588)4060749-5 (DE-588)4128912-2 (DE-588)4678063-4 (DE-588)4163872-4 (DE-588)4113937-9 |
title | Long-term psychobiological consequences of adverse childhood experiences implications for vulnerability and resilience |
title_auth | Long-term psychobiological consequences of adverse childhood experiences implications for vulnerability and resilience |
title_exact_search | Long-term psychobiological consequences of adverse childhood experiences implications for vulnerability and resilience |
title_exact_search_txtP | Long-term psychobiological consequences of adverse childhood experiences implications for vulnerability and resilience |
title_full | Long-term psychobiological consequences of adverse childhood experiences implications for vulnerability and resilience Gunther Pascal Meinlschmidt |
title_fullStr | Long-term psychobiological consequences of adverse childhood experiences implications for vulnerability and resilience Gunther Pascal Meinlschmidt |
title_full_unstemmed | Long-term psychobiological consequences of adverse childhood experiences implications for vulnerability and resilience Gunther Pascal Meinlschmidt |
title_short | Long-term psychobiological consequences of adverse childhood experiences |
title_sort | long term psychobiological consequences of adverse childhood experiences implications for vulnerability and resilience |
title_sub | implications for vulnerability and resilience |
topic | Psychisches Trauma (DE-588)4060749-5 gnd Neuroendokrines System (DE-588)4128912-2 gnd Regulationsstörung (DE-588)4678063-4 gnd Kindheitserinnerung (DE-588)4163872-4 gnd |
topic_facet | Psychisches Trauma Neuroendokrines System Regulationsstörung Kindheitserinnerung Hochschulschrift |
url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=014706189&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
work_keys_str_mv | AT meinlschmidtgunther longtermpsychobiologicalconsequencesofadversechildhoodexperiencesimplicationsforvulnerabilityandresilience |