Verfügbarkeit: Nutritional oncology

Nutritional oncology:

Gespeichert in:

Bibliographische Detailangaben
Format:	Buch
Sprache:	English
Veröffentlicht:	Amsterdam [u.a.] Elsevier, Acad. Press 2006
Ausgabe:	2. ed.
Schlagworte:	Neoplasms > diet therapy Neoplasms > etiology Neoplasms > prevention & control Nutrition Cancer - Aspect nutritionnel Cancer - Diétothérapie Neoplasias (dietoterapia) Cancer > Diet therapy Cancer > Nutritional aspects Diät Ernährung Krebs > Medizin Aufsatzsammlung
Online-Zugang:	Inhaltsverzeichnis
Beschreibung:	XXIV, 822 S. Ill., graph. Darst.
ISBN:	0120883937 9780120883936

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Datensatz im Suchindex

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adam_text	Contents Contributing Authors Preface Introduction: The Principles of Nutritional Oncology DAVID HEBER, AND JOHN MILNER 3. Biology ANNA VELCICH, L1DIJA KLAMPFER, JOHN MARIADASON, HELENA WANCAI YANG, JUDITH CHRISTMAN, BARBARA HEERDT, AND LEONARD 1. Biology of Nutrition and Cancer 1. DAVID HEBER Introduction Classification of Food and Dietary Quality Energetics and Obesity Protein Quality of Lipids, Fats, and Fatty Acids Fatty Acid Structure and Classification Quality of Carbohydrates Functional Foods Building Diets for Interventional Studies Conclusion References 2. JOHN MILNER Introduction Nutrigenetic Response Nutritional Epigenetics Transcriptomics and Microarray Technologies Beyond Nutrigenomics Conclusions References Introduction Fundamental Cell Biology of Malignant Transformation in the Colon Gene Expression Profiling Signaling Pathways and Transcriptional Factors in Intestinal Cell Maturation, Tissue Homeostasis, and Tumorigenesis Epigenetic Mechanisms of Altered Gene Expression Mitochondria: A Mechanism of Regulation and Integration References 4. Cells LASZLO G. Introduction Metabolic Hypothesis of Tumor Growth Applying Metabolic Control Analysis Metabolic Profiling of Cell Proliferation and Differentiation Relative Roles of Genomics, Proteomics, and Metabolomics in Cancer Research Future Directions References vi Contents 5. STEPHEN D. HURSTING, CONNIE J. ROGERS, SOMDAT MAHABIR, NOMELI P. NUNEZ, J. CARL BARRETT, SUSAN AND Introduction Physical Activity and Energy Balance Exercise and Energy Balance in Carcinogenesis Future Research Directions and Conclusions References 9. CATHERINE L. CARPENTER AND LESLIE BERNSTEIN Introduction Etiology of Obesity Obesity and Cancer Risk of Specific Sites Cancer Sites Suspected to Be Associated with Obesity Summary References 187 II. Epidemiology of Nutrition and Cancer 6. MARJORIE MCCULLOUGH AND EDWARD GIOVANNUCCI Introduction Study Designs Special Issues in Nutritional Epidemiology Gene-Diet Interactions Interpretation of Epidemiological Studies Summary References 7. and Cancer STEPHANIE A. SMITH-WARNER, EDWARD GIOVANNUCCI Published Reviews Individual Cancer Sites All Cancer Methodological Issues Summary References 8. Variety of Cancers? DAVID M. KLURFELD Introduction Whole Grains and Cancer Whole Grains and Gastrointestinal Tract Cancers Whole Grains and Nonintestinal Cancers Conclusions References 177 10. Cancers KARAM DIETRICH HOFFMANN Introduction Tobacco Carcinogenesis Nutrition and Tobacco-Related Cancers Summary References 202 219 11. ELISA Introduction Alcohol Consumption: Trends and Prevalence Alcoholic Beverages Composition Alcohol Metabolism Challenges in Studying Alcohol and Cancer Summary of the Epidemiological Evidence Alcohol Drinking and Cancer Survival Conclusions and Public Health Implications References 12. and Cancer RAMUNE RELIENE AND ROBERT Introduction Tobacco Smoke Particulate Matter Diesel Exhaust Particles Arsenic Chromium Conclusions References Contents vii III. Biological Approaches to Investigating Nutrition and Cancer 13. Carcinogenesis DAVID HEBER Introduction The IGF Axis and Energy Balance Estrogens and Cancer Androgens and Cancer Nuclear Receptor Superfamilies and Orphan Receptors Lipid Steroid and Xenobiotic Receptors Feed-Forward Loops and Upregulation of Metabolic Enzymes A Theoretical Model for Xenobiosis and in Cancer References 14. Cancer PAUL DAVIS, DAVID Introduction Antioxidant Conclusion References 298 15. JASON M. Introduction Sulfur Has Multiple Biological Roles Affecting Cancer Thiols in Cancer Chemoprevention Most Dietary and Chemical Carcinogens Are Bioactivated to Reactive The GSH System Protects Against Cancer by Detoxification of Reactive Electrophiles The Liver Functions to Maintain Systemic Supply Through an Cycle Optimal Sulfur Uncertain Dietary GSH Provides a Means to Decrease Risk from Direct-Acting Dietary Carcinogens Thiols in the Diet Function to Protect Against Direct-Acting Carcinogens in the Diet Thiols in Systems Act Independently to Increase the Specificity of Oxidative Stress and Carcinogenesis Glutathione Plays Opposing Roles in Carcinogenesis Thioredoxin is Overexpressed in Cancer Summary References 16. BENJAMIN BONAVIDA Introduction Immune Surveillance of Tumors Do Tumor Cells Express Tumor-Associated Antigens? Immune Response to Cancer Immunotherapy Future Considerations for Successful Immunotherapy References 17. Oncology Research JIN-RONG ZHOU Introduction An Overview of Animal Models Organ-Specific Animal Tumor Models Future Research Directions Conclusions References IV. Gene-Nutrient Interaction and Cancer Prevention 18. Cancer Prevention PETER GREENWALD AND JOHN MILNER Overview of the Nutrition-Cancer Relationship Discovery Development Delivery References viii Contents 19. CATHERINE L. CARPENTER Introduction Study Design and Assessment Methods of Dietary Assessment Nutritional Summary References 20. HOWARD PHILIP TAYLOR, AND SCOTT LIPPMAN Introduction International Epidemiological Observations Prostate Anatomy, Physiology, and Pathogenesis of Prostate Cancer Gene-Nutrient Interaction in Prostate Cancer Hormones, Obesity, and Prostate Cancer Conclusion and Future Directions of Research References 21. DAVID HEBER Introduction Breast Anatomy and Physiology Epidemiological Studies Endocrinology of Breast Cancer Exogenous Hormones and Breast Cancer Risk Macronutrient Intakes, Diet, Energy Balance, and Breast Cancer Risk Insulin Resistance and Breast Cancer: Proposed Mechanisms Abdominal Obesity and Breast Cancer Recurrence and Survival Alcohol and Genetics, Nongenetic Factors, and Gene-Nutrient Interaction in Breast Cancer References 22. HOMERS. BLACK Introduction The Nature of Ultraviolet Radiation The Skin Cancer Experimental Data on Nutritional Effects UV-Induced Skin Cancer and Dietary Modification Possible Mode of Action of Dietary Fatty Acids in Modulation of UV Carcinogenesis Clinical Studies of Nutritional Effects Conclusions References 412 23. LEO TREYZON, GORDON OHNING, AND DAVID Introduction The Multistep Process of Colorectal Carcinogenesis Inherited and Spontaneous Colon Cancer Nutritional Factors in Colon Cancer Nutrient-Nutrient Interactions Antioxidants and Phytochemicals Conclusion References 24. NAI-CHIEH YUKO YOU AND ZUO-FENG ZHANG Introduction Background Dietary Factors and Gastric Cancer Micronutrients Prevention Trials for Gastric Cancer Conclusion and Future Perspectives References 25. DIANE M. HARRIS, MANISH VAY LIANG W. GO Introduction Background Genes Altered in Sporadic Ductal Adenocarcinomas The Importance of Diet Metabolic Hypothesis for Pancreatic Cancer Future Directions References 26. ALLAN J. PANTUCK, RON L1EBERMAN, KELLY OLEG Background Smoking and Bladder Cancer Intrinsic Genetic Susceptibility Factors in Bladder Cancer Chemoprevention of Bladder Cancer The Future of Bladder Cancer Chemoprevention: A Rational Strategy for the Identification and Testing of New Agents Conclusions References Contents ix 27. Differentiation and Lymphoma 491 SVEN DE Introduction Retinoids 492 Retinoid Adult Cutaneous 1 Vitamin Ascorbic Acid Future Perspective References V. Bioactive Food Components and Botanical Approaches to Cancer 28. Prevention and Therapy MARY FRANCES PICCIANO, BARBARA E. COHEN, AND PAUL Introduction Prevalence of Dietary Supplement Usage Among People with Cancer and the General Population Role of Dietary Supplements in Cancer Prevention and During Therapy Conclusions References 29. MARÍA Introduction Carbohydrate Classification and Metabolism Dietary Fiber Carbohydrates and Cancer Simple Sugars and Cancer Glycémie Fiber and Cancer Summary and Conclusions References 30. HUSEYIN Introduction Fatty Acid Biosynthesis Epidemiológica!, Studies The Translation Initiation Connection Conclusion References 31. JOELLEN Overview: Calcium, Vitamin D, and Cancer Vitamin Endocrinology and Nutrition Cellular Mechanisms of Vitamin Modulation of Cell Turnover and Carcinogenesis by Vitamin Calcium and Cancer Risk Epidemiological and Clinical Studies on Vitamin D, Calcium, and Cancer Summary References 32. STEPHEN BARNES, JEEVAN PRASAIN, TRACY CHAO-CHENG WANG, HUANG-GE ZHANG, AND HELEN KIM Introduction History of Soy Food Materials Derived from Soybeans Chemistry and Biosynthesis of Isoflavones Soy and Human Health Predinical Experiments Exploring the Soy-Cancer Prevention Hypothesis Genistein Timing of Exposure to Soy in Humans Soy, Isoflavones, and Preexisting Breast Cancer Conclusion References 33. CLEMENT IP, JAMES MARSHALL, YOUNG НАПАО Introduction Breast Cancer Colon Cancer Selenium and Prostate Cancer Microarray Methods Searching for Potential Se Redox Future Directions Conclusion References Contents 34. RADHA M. BHEEMREDDY AND ELIZABETH H. JEFFERY Introduction Occurrence and Plants Epidemiological and Cancer Prevention Chemoprevention Studies in Animal Models Mechanisms of Cancer Prevention by Glucosinolate Derivatives Clinical Studies with Glucosinolate Derivatives Conclusion References 35. JANELLE M. LANDAU, JOSHUA D. LAMBERT, AND CHUNG S. YANG Introduction Tea Chemistry and Oxidation-Reduction Properties Inhibition of Carcinogenesis in Animal Models Mechanisms of Cancer Prevention Bioavailability and Metabolism Epidemiological Studies Intervention Studies Conclusions References 36. JOHN MILNER Introduction Bioactive Food Components and Their Metabolites Free Radicals and Garlic Epigenomics and Garlic Garlic and Transcriptomics Garlic and Proteomics Multiple Targets Interaction with Other Food Components References 37. NAVINDRA P. SEERAM Introduction Structural Types of Berry Bioactives Distribution of Berry Bioactives Chemoprevention Studies with Berry Bioactives Dietary Intake of Berry Bioactives Bioavailability and Metabolism of Berry Bioactives Conclusions and Future Directions References 624 38. Mevalonate Pathway Activities HUANBIAO MO AND CHARLES E. ELSON Introduction Isoprenoids: Pure and Mixed Part A: Postulated Isoprenoid-Mediated Action: Suppression of Farnesyl Protein Activity Part B: Postulated Isoprenoid-Mediated Action: Suppression of HMG CoA Reductase Activity Cancer Prevention Summary References VI. Nutritional Assessment and Support of the Cancer Patient 39. DAVID HEBER Introduction Malnutrition and Cachexia in Cancer Relative Roles of Anorexia and Metabolic Abnormalities Cancer Anorexia Approaches to the Treatment of Anorexia and Cachexia Clinical Recommendations for Anorexia and Cachexia Prevention and Treatment References 40. Cancer Survivor ANNE MCTIERNAN Introduction Obesity and Breast Cancer Mortality: Nonpatient Populations Overweight, Obesity, and Breast Cancer Prognosis Weight Gain After Diagnosis and Breast Cancer Outcomes Obesity and Development of Comorbidities in Breast Cancer Patients Obesity and Quality of Life in Breast Cancer Patients Contents xi Potential Mechanisms for an Adverse Prognostic Effect of Obesity Methods for Weight Loss and Maintenance for Breast Cancer Patients Summary References 41. Patient HEIDI J. SILVER, EVE Introduction Enterai Parenteral Nutrition Support Meeting Nutrient Goals Home Nutrition Support References VII: Guidelines and Practice 45. Nutrition ROBERT Introduction Description of the WINS Study Design Issues Important Statistical Issues Conduct of the Trial Statistical Analysis of the Trial Data Results of the Statistical Analysis of the Trial Data Summary Conclusions References 42. and Syndromes DAVID HEBER Endocrine Abnormalities in the Cancer Patient Paraneoplastic Syndromes Ectopie Ectopie Hormones Conclusion References 43. LINDA A. JACOBS AND ELLEN GIARELLI Introduction Survivorship Discussion and Future Directions References 710 46. Cancer Prevention and Treatment GEORGE L. BLACKBURN Introduction Cancer Rates and Causation Grading of Scientific Evidence History of Evidence-based Medicine Hierarchies of Evidence The Roles of RCTs and Observational Studies Methodology Advances in Observational Studies Factors Promoting Evolution in Hierarchies of Evidence Evolutions in Evidence-based Assessments of Research Quality Adapting to Uncertainty An Emerging State of the Art References Appendix 44. of Life N. Introduction Definition of Quality of Life Purpose of Quality of Life Measurement Quality of Life and Nutrition Exercise and Quality of Life Conclusion References 716 47. Prevention JOHANNA DWYER Introduction: History of Nutrition Guidelines in Public Health Current Nutrition Guidelines Individualizing the Radiant Pyramid Cancer-Specific Guidelines Nutrition Guidelines and the Future Conclusions References XII Contents 48. lauta Upper Cancers) Esophageal Cancer Gastric Cancer Colorectal Cancer Breast Cancer LungCancer Prostate Cancer Conclusions References
adam_txt	Contents Contributing Authors Preface Introduction: The Principles of Nutritional Oncology DAVID HEBER, AND JOHN MILNER 3. Biology ANNA VELCICH, L1DIJA KLAMPFER, JOHN MARIADASON, HELENA WANCAI YANG, JUDITH CHRISTMAN, BARBARA HEERDT, AND LEONARD 1. Biology of Nutrition and Cancer 1. DAVID HEBER Introduction Classification of Food and Dietary Quality Energetics and Obesity Protein Quality of Lipids, Fats, and Fatty Acids Fatty Acid Structure and Classification Quality of Carbohydrates Functional Foods Building Diets for Interventional Studies Conclusion References 2. JOHN MILNER Introduction Nutrigenetic Response Nutritional Epigenetics Transcriptomics and Microarray Technologies Beyond Nutrigenomics Conclusions References Introduction Fundamental Cell Biology of Malignant Transformation in the Colon Gene Expression Profiling Signaling Pathways and Transcriptional Factors in Intestinal Cell Maturation, Tissue Homeostasis, and Tumorigenesis Epigenetic Mechanisms of Altered Gene Expression Mitochondria: A Mechanism of Regulation and Integration References 4. Cells LASZLO G. Introduction Metabolic Hypothesis of Tumor Growth Applying Metabolic Control Analysis Metabolic Profiling of Cell Proliferation and Differentiation Relative Roles of Genomics, Proteomics, and Metabolomics in Cancer Research Future Directions References vi Contents 5. STEPHEN D. HURSTING, CONNIE J. ROGERS, SOMDAT MAHABIR, NOMELI P. NUNEZ, J. CARL BARRETT, SUSAN AND Introduction Physical Activity and Energy Balance Exercise and Energy Balance in Carcinogenesis Future Research Directions and Conclusions References 9. CATHERINE L. CARPENTER AND LESLIE BERNSTEIN Introduction Etiology of Obesity Obesity and Cancer Risk of Specific Sites Cancer Sites Suspected to Be Associated with Obesity Summary References 187 II. Epidemiology of Nutrition and Cancer 6. MARJORIE MCCULLOUGH AND EDWARD GIOVANNUCCI Introduction Study Designs Special Issues in Nutritional Epidemiology Gene-Diet Interactions Interpretation of Epidemiological Studies Summary References 7. and Cancer STEPHANIE A. SMITH-WARNER, EDWARD GIOVANNUCCI Published Reviews Individual Cancer Sites All Cancer Methodological Issues Summary References 8. Variety of Cancers? DAVID M. KLURFELD Introduction Whole Grains and Cancer Whole Grains and Gastrointestinal Tract Cancers Whole Grains and Nonintestinal Cancers Conclusions References 177 10. Cancers KARAM DIETRICH HOFFMANN Introduction Tobacco Carcinogenesis Nutrition and Tobacco-Related Cancers Summary References 202 219 11. ELISA Introduction Alcohol Consumption: Trends and Prevalence Alcoholic Beverages Composition Alcohol Metabolism Challenges in Studying Alcohol and Cancer Summary of the Epidemiological Evidence Alcohol Drinking and Cancer Survival Conclusions and Public Health Implications References 12. and Cancer RAMUNE RELIENE AND ROBERT Introduction Tobacco Smoke Particulate Matter Diesel Exhaust Particles Arsenic Chromium Conclusions References Contents vii III. Biological Approaches to Investigating Nutrition and Cancer 13. Carcinogenesis DAVID HEBER Introduction The IGF Axis and Energy Balance Estrogens and Cancer Androgens and Cancer Nuclear Receptor Superfamilies and Orphan Receptors Lipid Steroid and Xenobiotic Receptors Feed-Forward Loops and Upregulation of Metabolic Enzymes A Theoretical Model for Xenobiosis and in Cancer References 14. Cancer PAUL DAVIS, DAVID Introduction Antioxidant Conclusion References 298 15. JASON M. Introduction Sulfur Has Multiple Biological Roles Affecting Cancer Thiols in Cancer Chemoprevention Most Dietary and Chemical Carcinogens Are Bioactivated to Reactive The GSH System Protects Against Cancer by Detoxification of Reactive Electrophiles The Liver Functions to Maintain Systemic Supply Through an Cycle Optimal Sulfur Uncertain Dietary GSH Provides a Means to Decrease Risk from Direct-Acting Dietary Carcinogens Thiols in the Diet Function to Protect Against Direct-Acting Carcinogens in the Diet Thiols in Systems Act Independently to Increase the Specificity of Oxidative Stress and Carcinogenesis Glutathione Plays Opposing Roles in Carcinogenesis Thioredoxin is Overexpressed in Cancer Summary References 16. BENJAMIN BONAVIDA Introduction Immune Surveillance of Tumors Do Tumor Cells Express Tumor-Associated Antigens? Immune Response to Cancer Immunotherapy Future Considerations for Successful Immunotherapy References 17. Oncology Research JIN-RONG ZHOU Introduction An Overview of Animal Models Organ-Specific Animal Tumor Models Future Research Directions Conclusions References IV. Gene-Nutrient Interaction and Cancer Prevention 18. Cancer Prevention PETER GREENWALD AND JOHN MILNER Overview of the Nutrition-Cancer Relationship Discovery Development Delivery References viii Contents 19. CATHERINE L. CARPENTER Introduction Study Design and Assessment Methods of Dietary Assessment Nutritional Summary References 20. HOWARD PHILIP TAYLOR, AND SCOTT LIPPMAN Introduction International Epidemiological Observations Prostate Anatomy, Physiology, and Pathogenesis of Prostate Cancer Gene-Nutrient Interaction in Prostate Cancer Hormones, Obesity, and Prostate Cancer Conclusion and Future Directions of Research References 21. DAVID HEBER Introduction Breast Anatomy and Physiology Epidemiological Studies Endocrinology of Breast Cancer Exogenous Hormones and Breast Cancer Risk Macronutrient Intakes, Diet, Energy Balance, and Breast Cancer Risk Insulin Resistance and Breast Cancer: Proposed Mechanisms Abdominal Obesity and Breast Cancer Recurrence and Survival Alcohol and Genetics, Nongenetic Factors, and Gene-Nutrient Interaction in Breast Cancer References 22. HOMERS. BLACK Introduction The Nature of Ultraviolet Radiation The Skin Cancer Experimental Data on Nutritional Effects UV-Induced Skin Cancer and Dietary Modification Possible Mode of Action of Dietary Fatty Acids in Modulation of UV Carcinogenesis Clinical Studies of Nutritional Effects Conclusions References 412 23. LEO TREYZON, GORDON OHNING, AND DAVID Introduction The Multistep Process of Colorectal Carcinogenesis Inherited and Spontaneous Colon Cancer Nutritional Factors in Colon Cancer Nutrient-Nutrient Interactions Antioxidants and Phytochemicals Conclusion References 24. NAI-CHIEH YUKO YOU AND ZUO-FENG ZHANG Introduction Background Dietary Factors and Gastric Cancer Micronutrients Prevention Trials for Gastric Cancer Conclusion and Future Perspectives References 25. DIANE M. HARRIS, MANISH VAY LIANG W. GO Introduction Background Genes Altered in Sporadic Ductal Adenocarcinomas The Importance of Diet Metabolic Hypothesis for Pancreatic Cancer Future Directions References 26. ALLAN J. PANTUCK, RON L1EBERMAN, KELLY OLEG Background Smoking and Bladder Cancer Intrinsic Genetic Susceptibility Factors in Bladder Cancer Chemoprevention of Bladder Cancer The Future of Bladder Cancer Chemoprevention: A Rational Strategy for the Identification and Testing of New Agents Conclusions References Contents ix 27. Differentiation and Lymphoma 491 SVEN DE Introduction Retinoids 492 Retinoid Adult Cutaneous 1 Vitamin Ascorbic Acid Future Perspective References V. Bioactive Food Components and Botanical Approaches to Cancer 28. Prevention and Therapy MARY FRANCES PICCIANO, BARBARA E. COHEN, AND PAUL Introduction Prevalence of Dietary Supplement Usage Among People with Cancer and the General Population Role of Dietary Supplements in Cancer Prevention and During Therapy Conclusions References 29. MARÍA Introduction Carbohydrate Classification and Metabolism Dietary Fiber Carbohydrates and Cancer Simple Sugars and Cancer Glycémie Fiber and Cancer Summary and Conclusions References 30. HUSEYIN Introduction Fatty Acid Biosynthesis Epidemiológica!, Studies The Translation Initiation Connection Conclusion References 31. JOELLEN Overview: Calcium, Vitamin D, and Cancer Vitamin Endocrinology and Nutrition Cellular Mechanisms of Vitamin Modulation of Cell Turnover and Carcinogenesis by Vitamin Calcium and Cancer Risk Epidemiological and Clinical Studies on Vitamin D, Calcium, and Cancer Summary References 32. STEPHEN BARNES, JEEVAN PRASAIN, TRACY CHAO-CHENG WANG, HUANG-GE ZHANG, AND HELEN KIM Introduction History of Soy Food Materials Derived from Soybeans Chemistry and Biosynthesis of Isoflavones Soy and Human Health Predinical Experiments Exploring the Soy-Cancer Prevention Hypothesis Genistein Timing of Exposure to Soy in Humans Soy, Isoflavones, and Preexisting Breast Cancer Conclusion References 33. CLEMENT IP, JAMES MARSHALL, YOUNG НАПАО Introduction Breast Cancer Colon Cancer Selenium and Prostate Cancer Microarray Methods Searching for Potential Se Redox Future Directions Conclusion References Contents 34. RADHA M. BHEEMREDDY AND ELIZABETH H. JEFFERY Introduction Occurrence and Plants Epidemiological and Cancer Prevention Chemoprevention Studies in Animal Models Mechanisms of Cancer Prevention by Glucosinolate Derivatives Clinical Studies with Glucosinolate Derivatives Conclusion References 35. JANELLE M. LANDAU, JOSHUA D. LAMBERT, AND CHUNG S. YANG Introduction Tea Chemistry and Oxidation-Reduction Properties Inhibition of Carcinogenesis in Animal Models Mechanisms of Cancer Prevention Bioavailability and Metabolism Epidemiological Studies Intervention Studies Conclusions References 36. JOHN MILNER Introduction Bioactive Food Components and Their Metabolites Free Radicals and Garlic Epigenomics and Garlic Garlic and Transcriptomics Garlic and Proteomics Multiple Targets Interaction with Other Food Components References 37. NAVINDRA P. SEERAM Introduction Structural Types of Berry Bioactives Distribution of Berry Bioactives Chemoprevention Studies with Berry Bioactives Dietary Intake of Berry Bioactives Bioavailability and Metabolism of Berry Bioactives Conclusions and Future Directions References 624 38. Mevalonate Pathway Activities HUANBIAO MO AND CHARLES E. ELSON Introduction Isoprenoids: Pure and Mixed Part A: Postulated Isoprenoid-Mediated Action: Suppression of Farnesyl Protein Activity Part B: Postulated Isoprenoid-Mediated Action: Suppression of HMG CoA Reductase Activity Cancer Prevention Summary References VI. Nutritional Assessment and Support of the Cancer Patient 39. DAVID HEBER Introduction Malnutrition and Cachexia in Cancer Relative Roles of Anorexia and Metabolic Abnormalities Cancer Anorexia Approaches to the Treatment of Anorexia and Cachexia Clinical Recommendations for Anorexia and Cachexia Prevention and Treatment References 40. Cancer Survivor ANNE MCTIERNAN Introduction Obesity and Breast Cancer Mortality: Nonpatient Populations Overweight, Obesity, and Breast Cancer Prognosis Weight Gain After Diagnosis and Breast Cancer Outcomes Obesity and Development of Comorbidities in Breast Cancer Patients Obesity and Quality of Life in Breast Cancer Patients Contents xi Potential Mechanisms for an Adverse Prognostic Effect of Obesity Methods for Weight Loss and Maintenance for Breast Cancer Patients Summary References 41. Patient HEIDI J. SILVER, EVE Introduction Enterai Parenteral Nutrition Support Meeting Nutrient Goals Home Nutrition Support References VII: Guidelines and Practice 45. Nutrition ROBERT Introduction Description of the WINS Study Design Issues Important Statistical Issues Conduct of the Trial Statistical Analysis of the Trial Data Results of the Statistical Analysis of the Trial Data Summary Conclusions References 42. and Syndromes DAVID HEBER Endocrine Abnormalities in the Cancer Patient Paraneoplastic Syndromes Ectopie Ectopie Hormones Conclusion References 43. LINDA A. JACOBS AND ELLEN GIARELLI Introduction Survivorship Discussion and Future Directions References 710 46. Cancer Prevention and Treatment GEORGE L. BLACKBURN Introduction Cancer Rates and Causation Grading of Scientific Evidence History of Evidence-based Medicine Hierarchies of Evidence The Roles of RCTs and Observational Studies Methodology Advances in Observational Studies Factors Promoting Evolution in Hierarchies of Evidence Evolutions in Evidence-based Assessments of Research Quality Adapting to Uncertainty An Emerging State of the Art References Appendix 44. of Life N. Introduction Definition of Quality of Life Purpose of Quality of Life Measurement Quality of Life and Nutrition Exercise and Quality of Life Conclusion References 716 47. Prevention JOHANNA DWYER Introduction: History of Nutrition Guidelines in Public Health Current Nutrition Guidelines Individualizing the Radiant Pyramid Cancer-Specific Guidelines Nutrition Guidelines and the Future Conclusions References XII Contents 48. lauta Upper Cancers) Esophageal Cancer Gastric Cancer Colorectal Cancer Breast Cancer LungCancer Prostate Cancer Conclusions References
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id	DE-604.BV021266728
illustrated	Illustrated
index_date	2024-07-02T13:43:24Z
indexdate	2024-07-09T20:34:15Z
institution	BVB
isbn	0120883937 9780120883936
language	English
oai_aleph_id	oai:aleph.bib-bvb.de:BVB01-014587902
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open_access_boolean
owner	DE-M49 DE-BY-TUM DE-355 DE-BY-UBR
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physical	XXIV, 822 S. Ill., graph. Darst.
publishDate	2006
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publisher	Elsevier, Acad. Press
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spelling	Nutritional oncology ed.-in-chief: David Heber 2. ed. Amsterdam [u.a.] Elsevier, Acad. Press 2006 XXIV, 822 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Neoplasms diet therapy Neoplasms etiology Neoplasms prevention & control Nutrition Cancer - Aspect nutritionnel Cancer - Diétothérapie Neoplasias (dietoterapia) larpcal Cancer Diet therapy Cancer Nutritional aspects Diät (DE-588)4012031-4 gnd rswk-swf Ernährung (DE-588)4015332-0 gnd rswk-swf Krebs Medizin (DE-588)4073781-0 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Krebs Medizin (DE-588)4073781-0 s Diät (DE-588)4012031-4 s DE-604 Ernährung (DE-588)4015332-0 s Heber, David Sonstige (DE-588)124535585 oth Digitalisierung UB Regensburg application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=014587902&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis
spellingShingle	Nutritional oncology Neoplasms diet therapy Neoplasms etiology Neoplasms prevention & control Nutrition Cancer - Aspect nutritionnel Cancer - Diétothérapie Neoplasias (dietoterapia) larpcal Cancer Diet therapy Cancer Nutritional aspects Diät (DE-588)4012031-4 gnd Ernährung (DE-588)4015332-0 gnd Krebs Medizin (DE-588)4073781-0 gnd
subject_GND	(DE-588)4012031-4 (DE-588)4015332-0 (DE-588)4073781-0 (DE-588)4143413-4
title	Nutritional oncology
title_auth	Nutritional oncology
title_exact_search	Nutritional oncology
title_exact_search_txtP	Nutritional oncology
title_full	Nutritional oncology ed.-in-chief: David Heber
title_fullStr	Nutritional oncology ed.-in-chief: David Heber
title_full_unstemmed	Nutritional oncology ed.-in-chief: David Heber
title_short	Nutritional oncology
title_sort	nutritional oncology
topic	Neoplasms diet therapy Neoplasms etiology Neoplasms prevention & control Nutrition Cancer - Aspect nutritionnel Cancer - Diétothérapie Neoplasias (dietoterapia) larpcal Cancer Diet therapy Cancer Nutritional aspects Diät (DE-588)4012031-4 gnd Ernährung (DE-588)4015332-0 gnd Krebs Medizin (DE-588)4073781-0 gnd
topic_facet	Neoplasms diet therapy Neoplasms etiology Neoplasms prevention & control Nutrition Cancer - Aspect nutritionnel Cancer - Diétothérapie Neoplasias (dietoterapia) Cancer Diet therapy Cancer Nutritional aspects Diät Ernährung Krebs Medizin Aufsatzsammlung
url	http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=014587902&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA
work_keys_str_mv	AT heberdavid nutritionaloncology

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