Hydrolases in organic synthesis: regio- and stereoselective biotransformations
Gespeichert in:
Hauptverfasser: | , |
---|---|
Format: | Buch |
Sprache: | English |
Veröffentlicht: |
Weinheim
WILEY-VCH
2006
|
Ausgabe: | 2. ed. |
Schlagworte: | |
Online-Zugang: | Inhaltsverzeichnis |
Beschreibung: | XXII, 355 S. Ill., graph. Darst. |
ISBN: | 3527310290 9783527310296 |
Internformat
MARC
LEADER | 00000nam a2200000 c 4500 | ||
---|---|---|---|
001 | BV020851205 | ||
003 | DE-604 | ||
005 | 20080424 | ||
007 | t | ||
008 | 051031s2006 gw ad|| |||| 00||| eng d | ||
015 | |a 05,N28,1010 |2 dnb | ||
016 | 7 | |a 97534112X |2 DE-101 | |
020 | |a 3527310290 |c Gb. : ca. sfr 220.00 (freier Pr.), ca. EUR 139.00 (freier Pr.) |9 3-527-31029-0 | ||
020 | |a 9783527310296 |9 978-3-527-31029-6 | ||
024 | 3 | |a 9783527310296 | |
028 | 5 | 2 | |a 1131029 000 |
035 | |a (OCoLC)254491760 | ||
035 | |a (DE-599)BVBBV020851205 | ||
040 | |a DE-604 |b ger |e rakddb | ||
041 | 0 | |a eng | |
044 | |a gw |c XA-DE-BW | ||
049 | |a DE-91G |a DE-703 |a DE-1046 |a DE-19 |a DE-83 |a DE-11 |a DE-29T | ||
050 | 0 | |a QD262 | |
082 | 0 | |a 547.2 | |
084 | |a VK 5500 |0 (DE-625)147401:253 |2 rvk | ||
084 | |a VK 5800 |0 (DE-625)147412:253 |2 rvk | ||
084 | |a VS 5450 |0 (DE-625)147692:253 |2 rvk | ||
084 | |a VX 8550 |0 (DE-625)147830:253 |2 rvk | ||
084 | |a WD 4000 |0 (DE-625)148175: |2 rvk | ||
084 | |a CHE 624f |2 stub | ||
084 | |a 540 |2 sdnb | ||
084 | |a CHE 623f |2 stub | ||
100 | 1 | |a Bornscheuer, Uwe Theo |d 1964- |e Verfasser |0 (DE-588)121061841 |4 aut | |
245 | 1 | 0 | |a Hydrolases in organic synthesis |b regio- and stereoselective biotransformations |c Uwe T. Bornscheuer ; Romas J. Kazlauskas |
250 | |a 2. ed. | ||
264 | 1 | |a Weinheim |b WILEY-VCH |c 2006 | |
300 | |a XXII, 355 S. |b Ill., graph. Darst. | ||
336 | |b txt |2 rdacontent | ||
337 | |b n |2 rdamedia | ||
338 | |b nc |2 rdacarrier | ||
650 | 4 | |a Organische Synthese - Stereoselektivität - Enzymkatalyse - Hydrolasen | |
650 | 7 | |a Biotransformatie. |2 gtt | |
650 | 4 | |a Catalyse | |
650 | 4 | |a Catalysis | |
650 | 4 | |a Chemistry, Organic | |
650 | 4 | |a Composés organiques |x Synthèse | |
650 | 7 | |a Hydrolasen. |2 gtt | |
650 | 4 | |a Hydrolases | |
650 | 4 | |a Hydrolases |x chemistry | |
650 | 4 | |a Organic compounds |x Synthesis | |
650 | 7 | |a Stereoselectiviteit. |2 gtt | |
650 | 7 | |a Synthese (chemie) |2 gtt | |
650 | 0 | 7 | |a Organische Synthese |0 (DE-588)4075695-6 |2 gnd |9 rswk-swf |
650 | 0 | 7 | |a Stereoselektivität |0 (DE-588)4247497-8 |2 gnd |9 rswk-swf |
650 | 0 | 7 | |a Enzymkatalyse |0 (DE-588)4152480-9 |2 gnd |9 rswk-swf |
650 | 0 | 7 | |a Hydrolasen |0 (DE-588)4160916-5 |2 gnd |9 rswk-swf |
689 | 0 | 0 | |a Organische Synthese |0 (DE-588)4075695-6 |D s |
689 | 0 | 1 | |a Stereoselektivität |0 (DE-588)4247497-8 |D s |
689 | 0 | 2 | |a Enzymkatalyse |0 (DE-588)4152480-9 |D s |
689 | 0 | 3 | |a Hydrolasen |0 (DE-588)4160916-5 |D s |
689 | 0 | |5 DE-604 | |
700 | 1 | |a Kazlauskas, Romas J. |d 1956- |e Verfasser |0 (DE-588)121061868 |4 aut | |
856 | 4 | 2 | |m OEBV Datenaustausch |q application/pdf |u http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=014172909&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |3 Inhaltsverzeichnis |
Datensatz im Suchindex
_version_ | 1805076116168245248 |
---|---|
adam_text |
CONTENTS LNTRODUCTION 1 DESIGNING ENANTIOSELECTIVE REACTIONS 5 KINETIC
RESOLUTIONS 5 RECYCLING AND SEQUENTIAL KINETIC RESOLUTIONS 6 DYNAMIC
KINETIC RESOLUTIONS 9 INTRODUCTION 9 RACEMIZATION BY
PROTONATION/DEPROTONATION 1 0 RACEMIZATION BY ADDITIONIELIMINATION 14
RACEMIZATION BY NUCLEOPHILIC SUBSTITUTION 1 7 RACEMIZATION BY
OXIDATION/REDUCTION 17 RELATED STRATEGIES 22 ASYRNMETRIC SYNTHESES 23
CHOOSING REACTION MEDIA: WATER AND ORGANIC SOLVENTS 25 HYDROLYSIS IN
WATER 25 TRANSESTERIFICATIONS AND CONDENSATIONS IN ORGANIC SOLVENTS 25
INCREASING THE CATALYTIC ACTIVITY IN ORGANIC SOLVENTS 27 CHOOSING THE
BEST ORGANIC SOLVENT FOR HIGH ACTIVITY 27 INCREASING THE
ENANTIOSELECTIVITY IN ORGANIC SOLVENTS 28 WATER CONTENT AND WATER
ACTIVITY 30 OTHER REACTION MEDIA 32 IONIC LIQUIDS 32 REVERSE MICELLES 34
SUPERCRITICAL FLUIDS 36 IMMOBILIZATION 39 INTRODUCTION 39 LNCREASING THE
SURFACE AREA TO INCREASE CATALYTIC ACTIVITY 39 PROTEIN SOURCES AND
OPTIMIZATION OF BIOCATALYST PERFORMANCE 43 ACCESSING BIODIVERSITY 43
CREATING LMPROVED BIOCATALYSTS 44 DIRECTED EVOLUTION 45 METHODS TO
CREATE MUTANT LIBRARIES 45 ASSAY SYSTEMS 47 SELECTED EXAMPLES 50 FOCUSED
DIRECTED EVOLUTION 52 CATALYTIC PROMISCUITY IN HYDROLASES 54 REACTIONS
INVOLVING FUNCTIONAL GROUP ANALOGS 54 PERHYDROLASES 5 5 ALDOL AND
MICHAEL ADDITIONS CATALYZED BY HYDROLASES 56 ALDOL ADDITIONS 56
MICHAEL-TYPE ADDITIONS 57 MODIFICATIONS TO INTRODUCE NEW REACTIVITY IN
HYDROLASES 58 ENANTIOSELECTIVE REDUCTION OF HYDROPEROXIDES WITH
SELENOSUBTILISIN 58 VANADATE-MODIFIED PHOSPHATASES AS PEROXIDASES 59
LIPASES AND ESTERASES 61 AVAILABILITY, STRUCTURES AND PROPERTIES 61
LIPASES 62 CLASSIFICATION OF LIPASES 65 GENERAL FEATURES OF PPL, PCL,
CRL, CAL-B, AND RML 66 ESTERASES 68 LIPASES AND ESTERASES ARE A/SS
HYDROLASES 68 LID OR FLAP IN INTERFACIAL ACTIVATION OF LIPASES 70
SUBSTRATE BINDING SITE IN LIPASES AND ESTERASES 72 DESIGNING REACTIONS
WITH LIPASES AND ESTERASES 74 ACYL DONOR FOR ACYLATION REACTIONS 74
ASSAYS FOR LIPASES AND ESTERASES 77 REQUIREMENTS FOR A SUITABLE ASSAY 77
HOW TO DISTINGUISH BETWEEN LIPASE, ESTERASE, AND PROTEASE 83 SURVEY OF
ENANTIOSELECTIVE LIPASE-CATALYZED REACTIONS 84 ALCOHOLS 84 SECONDARY
ALCOHOLS 84 PRIMARY ALCOHOLS 106 OTHER ALCOHOLS, AMINES, AND ALCOHOL
ANALOGS 1 13 CARBOXYLIC ACIDS 124 GENERAL CONSIDERATIONS 124 CARBOXYLIC
ACIDS WITH A STEREOCENTER AT THE A-POSITION 124 CARBOXYLIC ACIDS WITH A
STEREOCENTER AT THE P-POSITION 128 OTHER CARBOXYLIC ACIDS 130 DOUBLE
ENANTIOSELECTION 13 1 ANHYDRIDES 1 32 LACTONES 133 COMMERCIAL
ENANTIOSELECTIVE REACTIONS 138 ENANTIOMERICALLY-PURE CHEMICAL
LNTERMEDIATES 138 ENANTIOMERICALLY-PURE PHARMACEUTICAL INTERMEDIATES 138
CHEMO- AND REGIOSELECTIVE LIPASE-CATALYZED REACTIONS 14 1 PROTECTION AND
DEPROTECTION REACTIONS 14 1 HYDROXYL GROUPS 141 AMINO GROUPS 159
CARBOXYL GROUPS 160 LIPID MODIFICATIONS 163 OLIGOMERIZATION AND
POLYMERIZATIONS 163 OTLIER LIPASE-CATALYZED REACTIONS 165 REACTIONS
CATALYZED BY ESTERASES 166 PIG LIVER ESTERASE 166 BIOCHERNICAL
PROPERTIES 166 RECORNBINANT PLE 167 OVERVIEW OF PLE SUBSTRATE
SPECIFICITY AND MODELS 169 ASYMMETRIZATION OF CARBOXYLIC ACIDS WITH A
STEREOCENTER AT THE A-POSITION 171 ASYRNMETRIZATION OF CARBOXYLIC ACIDS
WITH OTHER STEREOCENTERS 172 ASYMMETRIZATION OF PRIMARY AND SECONDARY
MESO-DIOLS 172 KINETIC RESOLUTION OF ALCOHOLS OR LACTONES 173 KINETIC
RESOLUTION OF CARBOXYLIC ACIDS 174 REACTIONS LNVOLVING MISCELLANEOUS
SUBSTRATES 174 ACETYLCHOLINE ESTERASE 175 BIOCHEMICAL PROPERTIES AND
APPLICATIONS IN ORGANIC SYNTHESES 175 OTHER MAMMALIAN ESTERASES 176
MICROBIAL ESTERASES 177 CARBOXYLESTERASE NP 18 1 OTHER MICROBIAL
ESTERASES 183 PROTEASES AND AMIDASES 185 OCCURRENCE AND AVAILABILITY OF
PROTEASES AND AMIDASES 185 GENERAL FEATURES OF SUBTILISIN,
CHYRNOTRYPSIN, AND OTHER PROTEASES AND AMIDASES 186 SUBSTRATE BINDING
NOMENCLATURE IN PROTEASES AND AMIDASES 186 SYNTHESIS OF AMIDE BONDS
USING PROTEASES AND AMIDASES 187 SUBTILISIN AND RELATED PROTEASES 189
CHYMOTRYPSIN 190 THERRNOLYSIN 190 PENICILLIN G ACYLASE 19 1 AMINO ACID
ACY LASES 19 1 PROTEASE ASSAYS 1 9 1 STRUCTURES OF PROTEASES AND
AMIDASES 193 SERINE PROTEASES - SUBTILISIN AND CHYMOTRYPSIN 193 SURVEY
OF ENANTIOSELECTIVE PROTEASE- AND AMIDASE-CATALYZED REACTIONS 195
ALCOHOLS AND AMINES 195 SECONDARY ALCOHOLS AND PRIRNARY AMINES 195
SECONDARY ARNINES 198 A-AMINO ACIDS VIA REACTIONS AT THE AMINO GROUP 199
CARBOXYLIC ACIDS 200 A-AMINO ACIDS VIA REACTIONS AT THE CARBOXYL GROUP
200 OTHER CARBOXYLIC ACIDS 207 COMMERCIAL ENANTIOSELECTIVE REACTIONS 209
PHOSPHOLIPASES 21 1 PHOSPHOLIPASE AL 2 1 1 PHOSPHOLIPASE A2 2 1 1
PHOSPHOLIPASE C 2 12 PHOSPHOLIPASE D 2 12 8 EPOXIDE HYDROLASES 215 8.1
LNTRODUCTION 2 15 8.2 MAMMALIAN EPOXIDE HYDROLASES 2 18 8.3 MICROBIAL
EPOXIDE HYDROIASES 220 8.3.1 BACTERIAI EPOXIDE HYDROLASES 220 8.3.2
FUNGAL AND YEAST EPOXIDE HYDROLASES 223 9 HYDROLYSIS OF NITRILES 227 9.1
INTRODUCTION 227 9.2 MILD CONDITIONS 233 9.3 REGIOSELECTIVE REACTIONS OF
DINITRILES 236 9.4 ENANTIOSELECTIVE REACTIONS 237 10 OTHER HYDROLASES
241 10.1 GLYCOSIDASES 24 1 10.2 HALOALCOHOL DEHALOGENASES 245 10.3
PHOSPHOTRIESTERASES 246 10.3.1 ORGANOPHOSPHORUS HYDROLASES 246 10.3.2
DIISOPROPYL FLUOROPHOSPHATASES 248 ABBREVIATIONS 249 REFERENCES 251
INDEX 347 |
adam_txt |
CONTENTS LNTRODUCTION 1 DESIGNING ENANTIOSELECTIVE REACTIONS 5 KINETIC
RESOLUTIONS 5 RECYCLING AND SEQUENTIAL KINETIC RESOLUTIONS 6 DYNAMIC
KINETIC RESOLUTIONS 9 INTRODUCTION 9 RACEMIZATION BY
PROTONATION/DEPROTONATION 1 0 RACEMIZATION BY ADDITIONIELIMINATION 14
RACEMIZATION BY NUCLEOPHILIC SUBSTITUTION 1 7 RACEMIZATION BY
OXIDATION/REDUCTION 17 RELATED STRATEGIES 22 ASYRNMETRIC SYNTHESES 23
CHOOSING REACTION MEDIA: WATER AND ORGANIC SOLVENTS 25 HYDROLYSIS IN
WATER 25 TRANSESTERIFICATIONS AND CONDENSATIONS IN ORGANIC SOLVENTS 25
INCREASING THE CATALYTIC ACTIVITY IN ORGANIC SOLVENTS 27 CHOOSING THE
BEST ORGANIC SOLVENT FOR HIGH ACTIVITY 27 INCREASING THE
ENANTIOSELECTIVITY IN ORGANIC SOLVENTS 28 WATER CONTENT AND WATER
ACTIVITY 30 OTHER REACTION MEDIA 32 IONIC LIQUIDS 32 REVERSE MICELLES 34
SUPERCRITICAL FLUIDS 36 IMMOBILIZATION 39 INTRODUCTION 39 LNCREASING THE
SURFACE AREA TO INCREASE CATALYTIC ACTIVITY 39 PROTEIN SOURCES AND
OPTIMIZATION OF BIOCATALYST PERFORMANCE 43 ACCESSING BIODIVERSITY 43
CREATING LMPROVED BIOCATALYSTS 44 DIRECTED EVOLUTION 45 METHODS TO
CREATE MUTANT LIBRARIES 45 ASSAY SYSTEMS 47 SELECTED EXAMPLES 50 FOCUSED
DIRECTED EVOLUTION 52 CATALYTIC PROMISCUITY IN HYDROLASES 54 REACTIONS
INVOLVING FUNCTIONAL GROUP ANALOGS 54 PERHYDROLASES 5 5 ALDOL AND
MICHAEL ADDITIONS CATALYZED BY HYDROLASES 56 ALDOL ADDITIONS 56
MICHAEL-TYPE ADDITIONS 57 MODIFICATIONS TO INTRODUCE NEW REACTIVITY IN
HYDROLASES 58 ENANTIOSELECTIVE REDUCTION OF HYDROPEROXIDES WITH
SELENOSUBTILISIN 58 VANADATE-MODIFIED PHOSPHATASES AS PEROXIDASES 59
LIPASES AND ESTERASES 61 AVAILABILITY, STRUCTURES AND PROPERTIES 61
LIPASES 62 CLASSIFICATION OF LIPASES 65 GENERAL FEATURES OF PPL, PCL,
CRL, CAL-B, AND RML 66 ESTERASES 68 LIPASES AND ESTERASES ARE A/SS
HYDROLASES 68 LID OR FLAP IN INTERFACIAL ACTIVATION OF LIPASES 70
SUBSTRATE BINDING SITE IN LIPASES AND ESTERASES 72 DESIGNING REACTIONS
WITH LIPASES AND ESTERASES 74 ACYL DONOR FOR ACYLATION REACTIONS 74
ASSAYS FOR LIPASES AND ESTERASES 77 REQUIREMENTS FOR A SUITABLE ASSAY 77
HOW TO DISTINGUISH BETWEEN LIPASE, ESTERASE, AND PROTEASE 83 SURVEY OF
ENANTIOSELECTIVE LIPASE-CATALYZED REACTIONS 84 ALCOHOLS 84 SECONDARY
ALCOHOLS 84 PRIMARY ALCOHOLS 106 OTHER ALCOHOLS, AMINES, AND ALCOHOL
ANALOGS 1 13 CARBOXYLIC ACIDS 124 GENERAL CONSIDERATIONS 124 CARBOXYLIC
ACIDS WITH A STEREOCENTER AT THE A-POSITION 124 CARBOXYLIC ACIDS WITH A
STEREOCENTER AT THE P-POSITION 128 OTHER CARBOXYLIC ACIDS 130 DOUBLE
ENANTIOSELECTION 13 1 ANHYDRIDES 1 32 LACTONES 133 COMMERCIAL
ENANTIOSELECTIVE REACTIONS 138 ENANTIOMERICALLY-PURE CHEMICAL
LNTERMEDIATES 138 ENANTIOMERICALLY-PURE PHARMACEUTICAL INTERMEDIATES 138
CHEMO- AND REGIOSELECTIVE LIPASE-CATALYZED REACTIONS 14 1 PROTECTION AND
DEPROTECTION REACTIONS 14 1 HYDROXYL GROUPS 141 AMINO GROUPS 159
CARBOXYL GROUPS 160 LIPID MODIFICATIONS 163 OLIGOMERIZATION AND
POLYMERIZATIONS 163 OTLIER LIPASE-CATALYZED REACTIONS 165 REACTIONS
CATALYZED BY ESTERASES 166 PIG LIVER ESTERASE 166 BIOCHERNICAL
PROPERTIES 166 RECORNBINANT PLE 167 OVERVIEW OF PLE SUBSTRATE
SPECIFICITY AND MODELS 169 ASYMMETRIZATION OF CARBOXYLIC ACIDS WITH A
STEREOCENTER AT THE A-POSITION 171 ASYRNMETRIZATION OF CARBOXYLIC ACIDS
WITH OTHER STEREOCENTERS 172 ASYMMETRIZATION OF PRIMARY AND SECONDARY
MESO-DIOLS 172 KINETIC RESOLUTION OF ALCOHOLS OR LACTONES 173 KINETIC
RESOLUTION OF CARBOXYLIC ACIDS 174 REACTIONS LNVOLVING MISCELLANEOUS
SUBSTRATES 174 ACETYLCHOLINE ESTERASE 175 BIOCHEMICAL PROPERTIES AND
APPLICATIONS IN ORGANIC SYNTHESES 175 OTHER MAMMALIAN ESTERASES 176
MICROBIAL ESTERASES 177 CARBOXYLESTERASE NP 18 1 OTHER MICROBIAL
ESTERASES 183 PROTEASES AND AMIDASES 185 OCCURRENCE AND AVAILABILITY OF
PROTEASES AND AMIDASES 185 GENERAL FEATURES OF SUBTILISIN,
CHYRNOTRYPSIN, AND OTHER PROTEASES AND AMIDASES 186 SUBSTRATE BINDING
NOMENCLATURE IN PROTEASES AND AMIDASES 186 SYNTHESIS OF AMIDE BONDS
USING PROTEASES AND AMIDASES 187 SUBTILISIN AND RELATED PROTEASES 189
CHYMOTRYPSIN 190 THERRNOLYSIN 190 PENICILLIN G ACYLASE 19 1 AMINO ACID
ACY LASES 19 1 PROTEASE ASSAYS 1 9 1 STRUCTURES OF PROTEASES AND
AMIDASES 193 SERINE PROTEASES - SUBTILISIN AND CHYMOTRYPSIN 193 SURVEY
OF ENANTIOSELECTIVE PROTEASE- AND AMIDASE-CATALYZED REACTIONS 195
ALCOHOLS AND AMINES 195 SECONDARY ALCOHOLS AND PRIRNARY AMINES 195
SECONDARY ARNINES 198 A-AMINO ACIDS VIA REACTIONS AT THE AMINO GROUP 199
CARBOXYLIC ACIDS 200 A-AMINO ACIDS VIA REACTIONS AT THE CARBOXYL GROUP
200 OTHER CARBOXYLIC ACIDS 207 COMMERCIAL ENANTIOSELECTIVE REACTIONS 209
PHOSPHOLIPASES 21 1 PHOSPHOLIPASE AL 2 1 1 PHOSPHOLIPASE A2 2 1 1
PHOSPHOLIPASE C 2 12 PHOSPHOLIPASE D 2 12 8 EPOXIDE HYDROLASES 215 8.1
LNTRODUCTION 2 15 8.2 MAMMALIAN EPOXIDE HYDROLASES 2 18 8.3 MICROBIAL
EPOXIDE HYDROIASES 220 8.3.1 BACTERIAI EPOXIDE HYDROLASES 220 8.3.2
FUNGAL AND YEAST EPOXIDE HYDROLASES 223 9 HYDROLYSIS OF NITRILES 227 9.1
INTRODUCTION 227 9.2 MILD CONDITIONS 233 9.3 REGIOSELECTIVE REACTIONS OF
DINITRILES 236 9.4 ENANTIOSELECTIVE REACTIONS 237 10 OTHER HYDROLASES
241 10.1 GLYCOSIDASES 24 1 10.2 HALOALCOHOL DEHALOGENASES 245 10.3
PHOSPHOTRIESTERASES 246 10.3.1 ORGANOPHOSPHORUS HYDROLASES 246 10.3.2
DIISOPROPYL FLUOROPHOSPHATASES 248 ABBREVIATIONS 249 REFERENCES 251
INDEX 347 |
any_adam_object | 1 |
any_adam_object_boolean | 1 |
author | Bornscheuer, Uwe Theo 1964- Kazlauskas, Romas J. 1956- |
author_GND | (DE-588)121061841 (DE-588)121061868 |
author_facet | Bornscheuer, Uwe Theo 1964- Kazlauskas, Romas J. 1956- |
author_role | aut aut |
author_sort | Bornscheuer, Uwe Theo 1964- |
author_variant | u t b ut utb r j k rj rjk |
building | Verbundindex |
bvnumber | BV020851205 |
callnumber-first | Q - Science |
callnumber-label | QD262 |
callnumber-raw | QD262 |
callnumber-search | QD262 |
callnumber-sort | QD 3262 |
callnumber-subject | QD - Chemistry |
classification_rvk | VK 5500 VK 5800 VS 5450 VX 8550 WD 4000 |
classification_tum | CHE 624f CHE 623f |
ctrlnum | (OCoLC)254491760 (DE-599)BVBBV020851205 |
dewey-full | 547.2 |
dewey-hundreds | 500 - Natural sciences and mathematics |
dewey-ones | 547 - Organic chemistry |
dewey-raw | 547.2 |
dewey-search | 547.2 |
dewey-sort | 3547.2 |
dewey-tens | 540 - Chemistry and allied sciences |
discipline | Chemie / Pharmazie Biologie Chemie |
discipline_str_mv | Chemie / Pharmazie Biologie Chemie |
edition | 2. ed. |
format | Book |
fullrecord | <?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>00000nam a2200000 c 4500</leader><controlfield tag="001">BV020851205</controlfield><controlfield tag="003">DE-604</controlfield><controlfield tag="005">20080424</controlfield><controlfield tag="007">t</controlfield><controlfield tag="008">051031s2006 gw ad|| |||| 00||| eng d</controlfield><datafield tag="015" ind1=" " ind2=" "><subfield code="a">05,N28,1010</subfield><subfield code="2">dnb</subfield></datafield><datafield tag="016" ind1="7" ind2=" "><subfield code="a">97534112X</subfield><subfield code="2">DE-101</subfield></datafield><datafield tag="020" ind1=" " ind2=" "><subfield code="a">3527310290</subfield><subfield code="c">Gb. : ca. sfr 220.00 (freier Pr.), ca. EUR 139.00 (freier Pr.)</subfield><subfield code="9">3-527-31029-0</subfield></datafield><datafield tag="020" ind1=" " ind2=" "><subfield code="a">9783527310296</subfield><subfield code="9">978-3-527-31029-6</subfield></datafield><datafield tag="024" ind1="3" ind2=" "><subfield code="a">9783527310296</subfield></datafield><datafield tag="028" ind1="5" ind2="2"><subfield code="a">1131029 000</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(OCoLC)254491760</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-599)BVBBV020851205</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-604</subfield><subfield code="b">ger</subfield><subfield code="e">rakddb</subfield></datafield><datafield tag="041" ind1="0" ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="044" ind1=" " ind2=" "><subfield code="a">gw</subfield><subfield code="c">XA-DE-BW</subfield></datafield><datafield tag="049" ind1=" " ind2=" "><subfield code="a">DE-91G</subfield><subfield code="a">DE-703</subfield><subfield code="a">DE-1046</subfield><subfield code="a">DE-19</subfield><subfield code="a">DE-83</subfield><subfield code="a">DE-11</subfield><subfield code="a">DE-29T</subfield></datafield><datafield tag="050" ind1=" " ind2="0"><subfield code="a">QD262</subfield></datafield><datafield tag="082" ind1="0" ind2=" "><subfield code="a">547.2</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">VK 5500</subfield><subfield code="0">(DE-625)147401:253</subfield><subfield code="2">rvk</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">VK 5800</subfield><subfield code="0">(DE-625)147412:253</subfield><subfield code="2">rvk</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">VS 5450</subfield><subfield code="0">(DE-625)147692:253</subfield><subfield code="2">rvk</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">VX 8550</subfield><subfield code="0">(DE-625)147830:253</subfield><subfield code="2">rvk</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">WD 4000</subfield><subfield code="0">(DE-625)148175:</subfield><subfield code="2">rvk</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">CHE 624f</subfield><subfield code="2">stub</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">540</subfield><subfield code="2">sdnb</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">CHE 623f</subfield><subfield code="2">stub</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Bornscheuer, Uwe Theo</subfield><subfield code="d">1964-</subfield><subfield code="e">Verfasser</subfield><subfield code="0">(DE-588)121061841</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Hydrolases in organic synthesis</subfield><subfield code="b">regio- and stereoselective biotransformations</subfield><subfield code="c">Uwe T. Bornscheuer ; Romas J. Kazlauskas</subfield></datafield><datafield tag="250" ind1=" " ind2=" "><subfield code="a">2. ed.</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="a">Weinheim</subfield><subfield code="b">WILEY-VCH</subfield><subfield code="c">2006</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">XXII, 355 S.</subfield><subfield code="b">Ill., graph. Darst.</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="b">n</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="b">nc</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Organische Synthese - Stereoselektivität - Enzymkatalyse - Hydrolasen</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">Biotransformatie.</subfield><subfield code="2">gtt</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Catalyse</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Catalysis</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Chemistry, Organic</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Composés organiques</subfield><subfield code="x">Synthèse</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">Hydrolasen.</subfield><subfield code="2">gtt</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Hydrolases</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Hydrolases</subfield><subfield code="x">chemistry</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Organic compounds</subfield><subfield code="x">Synthesis</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">Stereoselectiviteit.</subfield><subfield code="2">gtt</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">Synthese (chemie)</subfield><subfield code="2">gtt</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Organische Synthese</subfield><subfield code="0">(DE-588)4075695-6</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Stereoselektivität</subfield><subfield code="0">(DE-588)4247497-8</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Enzymkatalyse</subfield><subfield code="0">(DE-588)4152480-9</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Hydrolasen</subfield><subfield code="0">(DE-588)4160916-5</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="689" ind1="0" ind2="0"><subfield code="a">Organische Synthese</subfield><subfield code="0">(DE-588)4075695-6</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="0" ind2="1"><subfield code="a">Stereoselektivität</subfield><subfield code="0">(DE-588)4247497-8</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="0" ind2="2"><subfield code="a">Enzymkatalyse</subfield><subfield code="0">(DE-588)4152480-9</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="0" ind2="3"><subfield code="a">Hydrolasen</subfield><subfield code="0">(DE-588)4160916-5</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="0" ind2=" "><subfield code="5">DE-604</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Kazlauskas, Romas J.</subfield><subfield code="d">1956-</subfield><subfield code="e">Verfasser</subfield><subfield code="0">(DE-588)121061868</subfield><subfield code="4">aut</subfield></datafield><datafield tag="856" ind1="4" ind2="2"><subfield code="m">OEBV Datenaustausch</subfield><subfield code="q">application/pdf</subfield><subfield code="u">http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=014172909&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA</subfield><subfield code="3">Inhaltsverzeichnis</subfield></datafield></record></collection> |
id | DE-604.BV020851205 |
illustrated | Illustrated |
index_date | 2024-07-02T13:19:52Z |
indexdate | 2024-07-20T05:52:10Z |
institution | BVB |
isbn | 3527310290 9783527310296 |
language | English |
oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-014172909 |
oclc_num | 254491760 |
open_access_boolean | |
owner | DE-91G DE-BY-TUM DE-703 DE-1046 DE-19 DE-BY-UBM DE-83 DE-11 DE-29T |
owner_facet | DE-91G DE-BY-TUM DE-703 DE-1046 DE-19 DE-BY-UBM DE-83 DE-11 DE-29T |
physical | XXII, 355 S. Ill., graph. Darst. |
publishDate | 2006 |
publishDateSearch | 2006 |
publishDateSort | 2006 |
publisher | WILEY-VCH |
record_format | marc |
spelling | Bornscheuer, Uwe Theo 1964- Verfasser (DE-588)121061841 aut Hydrolases in organic synthesis regio- and stereoselective biotransformations Uwe T. Bornscheuer ; Romas J. Kazlauskas 2. ed. Weinheim WILEY-VCH 2006 XXII, 355 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Organische Synthese - Stereoselektivität - Enzymkatalyse - Hydrolasen Biotransformatie. gtt Catalyse Catalysis Chemistry, Organic Composés organiques Synthèse Hydrolasen. gtt Hydrolases Hydrolases chemistry Organic compounds Synthesis Stereoselectiviteit. gtt Synthese (chemie) gtt Organische Synthese (DE-588)4075695-6 gnd rswk-swf Stereoselektivität (DE-588)4247497-8 gnd rswk-swf Enzymkatalyse (DE-588)4152480-9 gnd rswk-swf Hydrolasen (DE-588)4160916-5 gnd rswk-swf Organische Synthese (DE-588)4075695-6 s Stereoselektivität (DE-588)4247497-8 s Enzymkatalyse (DE-588)4152480-9 s Hydrolasen (DE-588)4160916-5 s DE-604 Kazlauskas, Romas J. 1956- Verfasser (DE-588)121061868 aut OEBV Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=014172909&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
spellingShingle | Bornscheuer, Uwe Theo 1964- Kazlauskas, Romas J. 1956- Hydrolases in organic synthesis regio- and stereoselective biotransformations Organische Synthese - Stereoselektivität - Enzymkatalyse - Hydrolasen Biotransformatie. gtt Catalyse Catalysis Chemistry, Organic Composés organiques Synthèse Hydrolasen. gtt Hydrolases Hydrolases chemistry Organic compounds Synthesis Stereoselectiviteit. gtt Synthese (chemie) gtt Organische Synthese (DE-588)4075695-6 gnd Stereoselektivität (DE-588)4247497-8 gnd Enzymkatalyse (DE-588)4152480-9 gnd Hydrolasen (DE-588)4160916-5 gnd |
subject_GND | (DE-588)4075695-6 (DE-588)4247497-8 (DE-588)4152480-9 (DE-588)4160916-5 |
title | Hydrolases in organic synthesis regio- and stereoselective biotransformations |
title_auth | Hydrolases in organic synthesis regio- and stereoselective biotransformations |
title_exact_search | Hydrolases in organic synthesis regio- and stereoselective biotransformations |
title_exact_search_txtP | Hydrolases in organic synthesis regio- and stereoselective biotransformations |
title_full | Hydrolases in organic synthesis regio- and stereoselective biotransformations Uwe T. Bornscheuer ; Romas J. Kazlauskas |
title_fullStr | Hydrolases in organic synthesis regio- and stereoselective biotransformations Uwe T. Bornscheuer ; Romas J. Kazlauskas |
title_full_unstemmed | Hydrolases in organic synthesis regio- and stereoselective biotransformations Uwe T. Bornscheuer ; Romas J. Kazlauskas |
title_short | Hydrolases in organic synthesis |
title_sort | hydrolases in organic synthesis regio and stereoselective biotransformations |
title_sub | regio- and stereoselective biotransformations |
topic | Organische Synthese - Stereoselektivität - Enzymkatalyse - Hydrolasen Biotransformatie. gtt Catalyse Catalysis Chemistry, Organic Composés organiques Synthèse Hydrolasen. gtt Hydrolases Hydrolases chemistry Organic compounds Synthesis Stereoselectiviteit. gtt Synthese (chemie) gtt Organische Synthese (DE-588)4075695-6 gnd Stereoselektivität (DE-588)4247497-8 gnd Enzymkatalyse (DE-588)4152480-9 gnd Hydrolasen (DE-588)4160916-5 gnd |
topic_facet | Organische Synthese - Stereoselektivität - Enzymkatalyse - Hydrolasen Biotransformatie. Catalyse Catalysis Chemistry, Organic Composés organiques Synthèse Hydrolasen. Hydrolases Hydrolases chemistry Organic compounds Synthesis Stereoselectiviteit. Synthese (chemie) Organische Synthese Stereoselektivität Enzymkatalyse Hydrolasen |
url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=014172909&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
work_keys_str_mv | AT bornscheueruwetheo hydrolasesinorganicsynthesisregioandstereoselectivebiotransformations AT kazlauskasromasj hydrolasesinorganicsynthesisregioandstereoselectivebiotransformations |