Asthma prevention:
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
Boca Raton, Fla. [u.a.]
Taylor & Francis
2005
|
| Schriftenreihe: | Lung biology in health and disease
195 |
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis Klappentext |
| Beschreibung: | Includes bibliographical references and index |
| Beschreibung: | XVIII, 661 S. Ill., graph. Darst. 24 cm |
| ISBN: | 0824754093 |
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| 490 | 1 | |a Lung biology in health and disease |v 195 | |
| 500 | |a Includes bibliographical references and index | ||
| 650 | 4 | |a Asthme | |
| 650 | 4 | |a Asthme - Prévention | |
| 650 | 4 | |a Asthme - Traitement | |
| 650 | 4 | |a Asthme chez l'enfant - Prévention | |
| 650 | 4 | |a Asthma |x Prevention | |
| 650 | 4 | |a Asthma in children |x Prevention | |
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Datensatz im Suchindex
| _version_ | 1804134554970095616 |
|---|---|
| adam_text | CONTENTS
I. EPIDEMIOLOGY OF ASTHMA
1.
Malcolm R. Sears
I. Introduction
II. Definition and Diagnosis of Asthma
III. Airway Hyperresponsiveness as an Epidemiological Tool
IV. Atopy as an Epidemiological Tool
V. Recent Trends in Asthma Epidemiology
VI. Epidemiological Trends in Asthma Mortality
VII.
VIII.
IX. Epidemiological Perspective on Prevention of Asthma
References
2.
Fernando D. Martinez
I.
Introduction
21
II.
Incidence
22
III.
Severity and
Wheezing Episodes
22
IV.
Late Onset Wheezers
24
V.
Bronchial Hyperresponsiveness (BHR) and Lung Function
in Early Wheezing Phenotypes
25
VI.
Predicting Early Asthma
27
VII.
Early Development of
28
VIII.
Conclusions
30
References
30
xii
3.
Erika von Mutius
I. Introduction
II. Worldwide Distribution of Wheeze and Asthma
III. Contrasting Results from Developing and
Developed Countries
IV. East-West Gradient across Europe
V. Differences in Rural and Urban Populations
References
4.
Chakradhar
II.
5.
I.
Introduction
47
II.
Definition
48
III.
Epidemiology
48
IV.
Genotypie
52
V.
Phenotypic Features of Later Onset Asthma
54
VI.
Epidemiologie
58
VII.
Treatment and Prognosis
62
VIII.
Conclusions
62
References
63
IMMUNOLOGY IN THE EARLY DEVELOPMENT
OF ASTHMA
71
Ontogeny of the Immune Response
73
P.G.i
Holt and J. Rowe
I.
Introduction
73
II.
Ontogeny of Fetal Immune System
73
III.
Early Postnatal Development of Immune System
75
IV.
Early-Life Immunity to Infectious Agents and Vaccines
80
V.
Vaccination and Atopic Phenotype
82
VI.
Postnatal Development of Immune Function and
Susceptibility to Allergic Disease
83
References
85
6.
Marzena Krawiec
I. Introduction
II. Pathophysiology of Airway Inflammation in Children
Contents
III.
IV. Conclusion
References
Ш.
7.
Alexander
I. Introduction
II. Plethysmographic Measurements of Lung Volume
and Airway Resistance
III. Tidal Breath Analysis for Infant Pulmonary Function Testing
IV. Tidal Forced Expirations
V. Raised Volume Rapid Thoraco-Abdominal Compression
(RVRTC)
VI. Measurement of Functional Residual Capacity
by Gas Dilution
VII.
Forced Osculation
VIII.
IX. Factors Affecting Physiology in Infants and Children
X. Early Physiological Factors as Predictors of Future
Physiological Function and Asthma
XL Summary
References
8.
Sabine Hoffjan
I. Introduction
II. Laboratory Techniques and Study Designs
III. Genome-Wide Screens
IV. Candidate Gene Studies
V. Conclusion
References
9.
Trida
I. Introduction
II. Hay Fever, Eczema, and Allergic Sensitization
in Relation to Birth Order
III. Asthma and Birth Order
xiv
IV. Infections
V. Immune
VI. Day
VII. Multiple
VIII.
IX. Birth Order and Other Diseases
X. Summary
References
10.
G. Daniel Brooks and Robert
239
239
245
248
252
254
254
11.
Elizabeth A.
and Thomas A.E. Platts-Mills
I.
Introduction
II.
Asthma Inception
III.
Strategies for Preventing
IV.
Asthma Exacerbations
IV.
Preventive Strategies
V.
Conclusions
References
I.
Introduction
263
II.
Dust Mites
264
III.
Animal Dander Allergens
267
IV.
Allergens Derived from Fungi
270
V.
Cockroach Exposure
272
VI.
Relationship of Specific IgE Antibody Responses
and Total IgE in Asthma Patients
274
VII.
Conclusions
275
References
277
12.
Paolo Maria Matricardi
I. Odd Influence on Asthma of Certain Nonrespiratory
Infections (NRIs)
II. Testing Hygiene Hypothesis in Europe
III. Testing Hygiene Hypothesis in United States
IV. Does the Hygiene Hypothesis Explain Inner City Asthma?
V. Protection Provided by Nonrespiratory Infections
VI. Ability of
VII.
Contents
VIII. Bacteria:
IX. Parasites and Asthma
X. The Role of NRIs in Preventing and Treating Asthma
XL Conclusions
References
13.
Bengt Björksten
I. Introduction
II. Epidemiological Studies
III. Aspects of Microbial Ecology
IV. Concluding Remarks
References
14.
U.
I. Introduction and Definition
II. Assessment of Determinants
III. Natural History of Atopic Manifestations
IV. Hereditary Factors
V. Nongenetic Factors
VI. Issues Related to Prevention
VII.
References
15.
Rosalind J. Wright
I. Introduction
II. Life Stress Model
III. Asthma Paradigm: Link to Stress
IV. Psychological Stress and Endocrine System
V. Stress and
VI. Stress and Immune Function
VII.
VIII.
IX. Psychological Stress and Oxidative Stress
X. Genetics
XL Epidemiological Evidence
XII.
XIII.
Acknowledgment
References
xvi
16.
Anne L. Wright
I. Introduction
II. Background
III. Possible Explanations for Conflicting Observations
IV. Implications for Prevention
V. Conclusions
References
IV. TREATMENT
17.
Kristin M. Burkart, Megan
I. Excess Burden of Asthma in the Inner City
II. Causes of Excess Burdens of Asthma in Inner Cities
III. Asthma Prevention Strategies for Inner Cities
IV. Summary
References
18.
Stanley J. Szefler
I. Introduction
II. Managing Asthma in Children
III. Managing Asthma in Young Children
IV. When to Initiate
V. Evolution of Asthma Therapy and Potential
for Future Developments
VI. Conclusions
Acknowledgment
References
19.
Jacqueline Pongracic
I. Introduction
II. Principles of Allergen Avoidance
III. Environmental Control and Primary Prevention
IV. Summary
References
Contents
20.
Moisés
I. Introduction
II. Mechanisms of Immunotherapy
III. Efficacy and Safety of Specific Immunotherapy
IV.
of Immunotherapy
V. Immunotherapy and Progression of Rhinitis to Asthma
VI. Immunotherapy and Onset of New Allergic Sensitivities
VII.
VIII.
References
21.
Larry Borish
I. Introduction
II. Mechanisms of Cytokine Inhibition
III. Inhibitors of Cytokines Associated with Innate Immunity
IV. Immune Deviation: Stimulation of Thl-Like Responses
V. Inhibition of Th2 Cytokines
VI. Anti-Inflammatory Cytokines
VII.
References
22.
EM. Salagean, P.H. Howarth, and S.T.
I. Introduction
II. Serum IgE and Epidemiology
III. IgE structure, Synthesis and Cell Interactions
IV. Anti-IgE and Its Development as Therapy
V. Therapeutic Potential of Omalizumab
VI. Other Approaches to Neutralizing IgE
VII.
References
23. DNA
David H. Broide
I. Introduction
II. Immunostimulatory
xviii
III.
IV. Allergen Gene Vaccines and Asthma
V. Conclusion
Acknowledgment
References
24. DNA
Kunihiko Kitagaki and Joel
I. Introduction
II. Epidemiology of Asthma: Are Microbial Infections
Naturally Protective?
III. Pathogenesis of Asthma: Imbalance of Thl and Th2?
IV. Immunostimulatory
V. Signal Transduction of CpG
VI. CpG
VII. CpG-ODN
VIII.
IX. Future Directions
Acknowledgment
References
25.
Jeffrey Stokes, Christopher Clark, and Thomas B.
I. Introduction
II. Immune-Modifying Therapies
III. Environmentally Based Therapies
IV. Conclusion
References
26.
Lisa Cameron and
I. Introduction
II. Induction of IgE Synthesis: Intercellular Interactions
III. Induction of IgE Synthesis: Molecular Events
IV. Modulating IgE Synthesis: Bench to Bedside
V. Conclusions
References
Index
about the book
Collecting research from leading specialists in the field, this reference contains the latest
studies on the genetic and environmental origins, pathogenesis, and immunology of asth-
Ш
tions in the prevention of this common disease.
Considers the role of environmental and social
With sections on airway-respiratory infection interactions, emerging therapies, and genetics,
this guide studies the natural history of asthma from birth-to adulthood-
characterization of various asthmatic phenotypes based on gender, age, ethnicity, and race
within various environments.
their role in immunoinflammatory events characteristic of allergic respiratory tract dis¬
eases.
genesis... and assesses currently available and promising treatment strategies in the context
of primary, secondary, and tertiary prevention of asthma and allergic disease.
about the editors
WILLIAM W.
Clinical Immunology, Department of Medicine, and Director of the General Clinical
Research Center, University of Wisconsin School of Medicine, Madison. Dr.
funded by the National Institutes of Health for research on the mechanisms of asthma and
me role of respiratory infections in asthma. His current research projects focus on mecha¬
nisms of vims-induced asmma, asthma from
mechanism of asthma, and mechanisms of severe asthma. Dr.
Feüow
ship in several other
American
Ље
ROBERT
Wiscoasiti School of
bmnunołogy,
Hospital,
dys&netion and mechanisms underlying the inception of childhood asthma. Dr. Lemanske
has authored or
over
ЖАГО
Pediatrie
Blood
and his
National
|
| adam_txt |
CONTENTS
I. EPIDEMIOLOGY OF ASTHMA
1.
Malcolm R. Sears
I. Introduction
II. Definition and Diagnosis of Asthma
III. Airway Hyperresponsiveness as an Epidemiological Tool
IV. Atopy as an Epidemiological Tool
V. Recent Trends in Asthma Epidemiology
VI. Epidemiological Trends in Asthma Mortality
VII.
VIII.
IX. Epidemiological Perspective on Prevention of Asthma
References
2.
Fernando D. Martinez
I.
Introduction
21
II.
Incidence
22
III.
Severity and
Wheezing Episodes
22
IV.
Late Onset Wheezers
24
V.
Bronchial Hyperresponsiveness (BHR) and Lung Function
in Early Wheezing Phenotypes
25
VI.
Predicting Early Asthma
27
VII.
Early Development of
28
VIII.
Conclusions
30
References
30
xii
3.
Erika von Mutius
I. Introduction
II. Worldwide Distribution of Wheeze and Asthma
III. Contrasting Results from Developing and
Developed Countries
IV. East-West Gradient across Europe
V. Differences in Rural and Urban Populations
References
4.
Chakradhar
II.
5.
I.
Introduction
47
II.
Definition
48
III.
Epidemiology
48
IV.
Genotypie
52
V.
Phenotypic Features of Later Onset Asthma
54
VI.
Epidemiologie
58
VII.
Treatment and Prognosis
62
VIII.
Conclusions
62
References
63
IMMUNOLOGY IN THE EARLY DEVELOPMENT
OF ASTHMA
71
Ontogeny of the Immune Response
73
P.G.i
Holt and J. Rowe
I.
Introduction
73
II.
Ontogeny of Fetal Immune System
73
III.
Early Postnatal Development of Immune System
75
IV.
Early-Life Immunity to Infectious Agents and Vaccines
80
V.
Vaccination and Atopic Phenotype
82
VI.
Postnatal Development of Immune Function and
Susceptibility to Allergic Disease
83
References
85
6.
Marzena Krawiec
I. Introduction
II. Pathophysiology of Airway Inflammation in Children
Contents
III.
IV. Conclusion
References
Ш.
7.
Alexander
I. Introduction
II. Plethysmographic Measurements of Lung Volume
and Airway Resistance
III. Tidal Breath Analysis for Infant Pulmonary Function Testing
IV. Tidal Forced Expirations
V. Raised Volume Rapid Thoraco-Abdominal Compression
(RVRTC)
VI. Measurement of Functional Residual Capacity
by Gas Dilution
VII.
Forced Osculation
VIII.
IX. Factors Affecting Physiology in Infants and Children
X. Early Physiological Factors as Predictors of Future
Physiological Function and Asthma
XL Summary
References
8.
Sabine Hoffjan
I. Introduction
II. Laboratory Techniques and Study Designs
III. Genome-Wide Screens
IV. Candidate Gene Studies
V. Conclusion
References
9.
Trida
I. Introduction
II. Hay Fever, Eczema, and Allergic Sensitization
in Relation to Birth Order
III. Asthma and Birth Order
xiv
IV. Infections
V. Immune
VI. Day
VII. Multiple
VIII.
IX. Birth Order and Other Diseases
X. Summary
References
10.
G. Daniel Brooks and Robert
239
239
245
248
252
254
254
11.
Elizabeth A.
and Thomas A.E. Platts-Mills
I.
Introduction
II.
Asthma Inception
III.
Strategies for Preventing
IV.
Asthma Exacerbations
IV.
Preventive Strategies
V.
Conclusions
References
I.
Introduction
263
II.
Dust Mites
264
III.
Animal Dander Allergens
267
IV.
Allergens Derived from Fungi
270
V.
Cockroach Exposure
272
VI.
Relationship of Specific IgE Antibody Responses
and Total IgE in Asthma Patients
274
VII.
Conclusions
275
References
277
12.
Paolo Maria Matricardi
I. Odd Influence on Asthma of Certain Nonrespiratory
Infections (NRIs)
II. Testing Hygiene Hypothesis in Europe
III. Testing Hygiene Hypothesis in United States
IV. Does the Hygiene Hypothesis Explain Inner City Asthma?
V. Protection Provided by Nonrespiratory Infections
VI. Ability of
VII.
Contents
VIII. Bacteria:
IX. Parasites and Asthma
X. The Role of NRIs in Preventing and Treating Asthma
XL Conclusions
References
13.
Bengt Björksten
I. Introduction
II. Epidemiological Studies
III. Aspects of Microbial Ecology
IV. Concluding Remarks
References
14.
U.
I. Introduction and Definition
II. Assessment of Determinants
III. Natural History of Atopic Manifestations
IV. Hereditary Factors
V. Nongenetic Factors
VI. Issues Related to Prevention
VII.
References
15.
Rosalind J. Wright
I. Introduction
II. Life Stress Model
III. Asthma Paradigm: Link to Stress
IV. Psychological Stress and Endocrine System
V. Stress and
VI. Stress and Immune Function
VII.
VIII.
IX. Psychological Stress and Oxidative Stress
X. Genetics
XL Epidemiological Evidence
XII.
XIII.
Acknowledgment
References
xvi
16.
Anne L. Wright
I. Introduction
II. Background
III. Possible Explanations for Conflicting Observations
IV. Implications for Prevention
V. Conclusions
References
IV. TREATMENT
17.
Kristin M. Burkart, Megan
I. Excess Burden of Asthma in the Inner City
II. Causes of Excess Burdens of Asthma in Inner Cities
III. Asthma Prevention Strategies for Inner Cities
IV. Summary
References
18.
Stanley J. Szefler
I. Introduction
II. Managing Asthma in Children
III. Managing Asthma in Young Children
IV. When to Initiate
V. Evolution of Asthma Therapy and Potential
for Future Developments
VI. Conclusions
Acknowledgment
References
19.
Jacqueline Pongracic
I. Introduction
II. Principles of Allergen Avoidance
III. Environmental Control and Primary Prevention
IV. Summary
References
Contents
20.
Moisés
I. Introduction
II. Mechanisms of Immunotherapy
III. Efficacy and Safety of Specific Immunotherapy
IV.
of Immunotherapy
V. Immunotherapy and Progression of Rhinitis to Asthma
VI. Immunotherapy and Onset of New Allergic Sensitivities
VII.
VIII.
References
21.
Larry Borish
I. Introduction
II. Mechanisms of Cytokine Inhibition
III. Inhibitors of Cytokines Associated with Innate Immunity
IV. Immune Deviation: Stimulation of Thl-Like Responses
V. Inhibition of Th2 Cytokines
VI. Anti-Inflammatory Cytokines
VII.
References
22.
EM. Salagean, P.H. Howarth, and S.T.
I. Introduction
II. Serum IgE and Epidemiology
III. IgE structure, Synthesis and Cell Interactions
IV. Anti-IgE and Its Development as Therapy
V. Therapeutic Potential of Omalizumab
VI. Other Approaches to Neutralizing IgE
VII.
References
23. DNA
David H. Broide
I. Introduction
II. Immunostimulatory
xviii
III.
IV. Allergen Gene Vaccines and Asthma
V. Conclusion
Acknowledgment
References
24. DNA
Kunihiko Kitagaki and Joel
I. Introduction
II. Epidemiology of Asthma: Are Microbial Infections
Naturally Protective?
III. Pathogenesis of Asthma: Imbalance of Thl and Th2?
IV. Immunostimulatory
V. Signal Transduction of CpG
VI. CpG
VII. CpG-ODN
VIII.
IX. Future Directions
Acknowledgment
References
25.
Jeffrey Stokes, Christopher Clark, and Thomas B.
I. Introduction
II. Immune-Modifying Therapies
III. Environmentally Based Therapies
IV. Conclusion
References
26.
Lisa Cameron and
I. Introduction
II. Induction of IgE Synthesis: Intercellular Interactions
III. Induction of IgE Synthesis: Molecular Events
IV. Modulating IgE Synthesis: Bench to Bedside
V. Conclusions
References
Index
about the book
Collecting research from leading specialists in the field, this reference contains the latest
studies on the genetic and environmental origins, pathogenesis, and immunology of asth-
Ш
tions in the prevention of this common disease.
Considers the role of environmental and social
With sections on airway-respiratory infection interactions, emerging therapies, and genetics,
this guide studies the natural history of asthma from birth-to adulthood-
characterization of various asthmatic phenotypes based on gender, age, ethnicity, and race
within various environments.
their role in immunoinflammatory events characteristic of allergic respiratory tract dis¬
eases.
genesis. and assesses currently available and promising treatment strategies in the context
of primary, secondary, and tertiary prevention of asthma and allergic disease.
about the editors
WILLIAM W.
Clinical Immunology, Department of Medicine, and Director of the General Clinical
Research Center, University of Wisconsin School of Medicine, Madison. Dr.
funded by the National Institutes of Health for research on the mechanisms of asthma and
me role of respiratory infections in asthma. His current research projects focus on mecha¬
nisms of vims-induced asmma, asthma from
mechanism of asthma, and mechanisms of severe asthma. Dr.
Feüow
ship in several other
American
Ље
ROBERT
Wiscoasiti School of
bmnunołogy,
Hospital,
dys&netion and mechanisms underlying the inception of childhood asthma. Dr. Lemanske
has authored or
over
ЖАГО
Pediatrie
Blood
and his
National |
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| genre | (DE-588)4143413-4 Aufsatzsammlung gnd-content |
| genre_facet | Aufsatzsammlung |
| id | DE-604.BV020844932 |
| illustrated | Illustrated |
| index_date | 2024-07-02T13:18:02Z |
| indexdate | 2024-07-09T20:26:28Z |
| institution | BVB |
| isbn | 0824754093 |
| language | English |
| lccn | 2005051484 |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-014166738 |
| oclc_num | 61027814 |
| open_access_boolean | |
| owner | DE-12 DE-355 DE-BY-UBR |
| owner_facet | DE-12 DE-355 DE-BY-UBR |
| physical | XVIII, 661 S. Ill., graph. Darst. 24 cm |
| publishDate | 2005 |
| publishDateSearch | 2005 |
| publishDateSort | 2005 |
| publisher | Taylor & Francis |
| record_format | marc |
| series | Lung biology in health and disease |
| series2 | Lung biology in health and disease |
| spelling | Asthma prevention ed. by William W. Busse ... Boca Raton, Fla. [u.a.] Taylor & Francis 2005 XVIII, 661 S. Ill., graph. Darst. 24 cm txt rdacontent n rdamedia nc rdacarrier Lung biology in health and disease 195 Includes bibliographical references and index Asthme Asthme - Prévention Asthme - Traitement Asthme chez l'enfant - Prévention Asthma Prevention Asthma in children Prevention Ätiologie (DE-588)4000646-3 gnd rswk-swf Bronchialasthma (DE-588)4069674-1 gnd rswk-swf Therapie (DE-588)4059798-2 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Bronchialasthma (DE-588)4069674-1 s Ätiologie (DE-588)4000646-3 s DE-604 Therapie (DE-588)4059798-2 s b DE-604 Busse, William W. Sonstige oth Lung biology in health and disease 195 (DE-604)BV000008326 195 Digitalisierung UB Regensburg application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=014166738&sequence=000003&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis Digitalisierung UB Regensburg application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=014166738&sequence=000004&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA Klappentext |
| spellingShingle | Asthma prevention Lung biology in health and disease Asthme Asthme - Prévention Asthme - Traitement Asthme chez l'enfant - Prévention Asthma Prevention Asthma in children Prevention Ätiologie (DE-588)4000646-3 gnd Bronchialasthma (DE-588)4069674-1 gnd Therapie (DE-588)4059798-2 gnd |
| subject_GND | (DE-588)4000646-3 (DE-588)4069674-1 (DE-588)4059798-2 (DE-588)4143413-4 |
| title | Asthma prevention |
| title_auth | Asthma prevention |
| title_exact_search | Asthma prevention |
| title_exact_search_txtP | Asthma prevention |
| title_full | Asthma prevention ed. by William W. Busse ... |
| title_fullStr | Asthma prevention ed. by William W. Busse ... |
| title_full_unstemmed | Asthma prevention ed. by William W. Busse ... |
| title_short | Asthma prevention |
| title_sort | asthma prevention |
| topic | Asthme Asthme - Prévention Asthme - Traitement Asthme chez l'enfant - Prévention Asthma Prevention Asthma in children Prevention Ätiologie (DE-588)4000646-3 gnd Bronchialasthma (DE-588)4069674-1 gnd Therapie (DE-588)4059798-2 gnd |
| topic_facet | Asthme Asthme - Prévention Asthme - Traitement Asthme chez l'enfant - Prévention Asthma Prevention Asthma in children Prevention Ätiologie Bronchialasthma Therapie Aufsatzsammlung |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=014166738&sequence=000003&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=014166738&sequence=000004&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA |
| volume_link | (DE-604)BV000008326 |
| work_keys_str_mv | AT bussewilliamw asthmaprevention |