Chemokines, chemokine receptors, and disease:
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
Amsterdam [u.a.]
Elsevier Acad. Press
2005
|
| Schriftenreihe: | Current topics in membranes
55 |
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | XIX, 380 S., [5] Bl. Ill., graph. Darst. |
| ISBN: | 0121533557 9780121533557 |
Internformat
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| 245 | 1 | 0 | |a Chemokines, chemokine receptors, and disease |c ed. by Lisa M. Schwiebert |
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Datensatz im Suchindex
| _version_ | 1804134154548281344 |
|---|---|
| adam_text | Contents
Contributors xi
Foreword xv
Previous Volumes in Series xvii
CHAPTER 1 Overview and History of Chemokines and
Their Receptors
Tina M. Calderon and Joan W. Berman
I. Chemokines: General Overview 1
II. Chemokine Receptors: General Overview 14
III. Chemokines and Chemokine Receptors in
Inflammation In Vivo 18
IV. An Expanding Role for Chemokines 21
References 21
CHAPTER 2 The Biology of CXC Chemokines and Their Receptors
Nathaniel M. Weathington and J. Edwin Blalock
I. Introduction 49
II. Genetic and Protein Structure of the CXC
Chemokine Family 50
III. The Biochemical Signal 61
IV. Communications of the CXC Chemokines 63
References 67
CHAPTER 3 The Molecular and Cellular Biology of CC
Chemokines and Their Receptors
James M. Fox and James E. Pease
I. Introduction 73
II. CC Chemokines 74
III. CC Chemokine Receptors 74
IV. Aspects of CC Chemokine Structure 78
V. Structural Determinants of Ligand Binding and
Receptor Activation by CC Chemokines 79
V
viij Contents
III. Animal Models of Atherosclerosis 226 i
IV. Chemokines and Atherosclerosis 227
V. Therapeutic Strategies for Modulating I
Chemokine Receptor Interactions 235 i
VI. Unanswered Questions and Future Directions 240
References 242
CHAPTER 10 CXC Chemokines in Cancer
Robert M. Stricter, Marie D. Burdick, Ammar Sakkour,
Nib O. Arnaiz, John A. Belperio, and Michael P. Keane
I. Introduction 256
II. Evidence That CXC Chemokines are Involved in
Cellular Transformation Relevant to
Preneoplastic to Neoplastic Transformation 256
III. Evidence That Chemokines are Involved in the
Regulation of Angiogenesis in Tumors 258
IV. ELR+ CXC Chemokines Promote Angiogenesis
Associated with Tumorigenesis 265
V. Non ELR+ CXC Chemokines Weaken Angiogenesis
Associated with Tumorigenesis 270
VI. The Concept of Immunoangiostasis : The Role
of CXCR3/CXCR3 Ligand Biological Axis
in Mediating Thl Cell Mediated Immunity
and Angiostasis 272
VII. Evidence That Chemokines are Involved in
Tumor Cell Invasion 275
VIII. Evidence That Chemokines Regulate the Pattern of
Organ Specific Metastasis of Cancer 277
IX. Conclusion 280
References 280
CHAPTER 11 Chemokines and Chemokine Receptors in
Infectious Disease
Karoll J. Cortez, Julia O. Jackson, and Shyam Kottilil
I. Introduction 290
II. Human Chemokine Receptors as Entry Factors for
Infectious Agents 292
III. Viral Strategies to Circumvent
Chemokine Systems 305
IV. Strategies for Blocking the Chemokine System in
Infectious Disease 309
Contents ix
V. Future Directions 317
References 320
CHAPTER 12 New Therapies Targeting Chemokine Receptors: Can
Changing the Way Cells Traffic be Used to Treat
Human Disease?
Linda Bendall and Kenneth Bradstock
I. Introduction 331
II. Available Drugs That Modulate
Chemokine/Receptor Function 333
III. Clinical Uses for
Chemokine Receptor Antagonists 338
IV. Discussion 349
References 350
Index 367
|
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| dewey-tens | 570 - Biology |
| discipline | Biologie |
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| indexdate | 2024-07-09T20:20:06Z |
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| isbn | 0121533557 9780121533557 |
| language | English |
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| series | Current topics in membranes |
| series2 | Current topics in membranes |
| spelling | Chemokines, chemokine receptors, and disease ed. by Lisa M. Schwiebert Amsterdam [u.a.] Elsevier Acad. Press 2005 XIX, 380 S., [5] Bl. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Current topics in membranes 55 Chemokines gtt Chimiokines Chimiokines - Physiopathologie Chimiokines - Récepteurs Ziekten gtt Chemokines Chemokines Pathophysiology Chemokines Receptors Chemokines physiology Receptors, Chemokine physiology Signal Transduction physiology Chemokine (DE-588)4429989-8 gnd rswk-swf Membranrezeptor (DE-588)4136267-6 gnd rswk-swf Pathobiochemie (DE-588)4044888-5 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Chemokine (DE-588)4429989-8 s DE-604 Pathobiochemie (DE-588)4044888-5 s Membranrezeptor (DE-588)4136267-6 s b DE-604 Schwiebert, Lisa M. Sonstige oth Current topics in membranes 55 (DE-604)BV036839511 55 HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=013830682&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Chemokines, chemokine receptors, and disease Current topics in membranes Chemokines gtt Chimiokines Chimiokines - Physiopathologie Chimiokines - Récepteurs Ziekten gtt Chemokines Chemokines Pathophysiology Chemokines Receptors Chemokines physiology Receptors, Chemokine physiology Signal Transduction physiology Chemokine (DE-588)4429989-8 gnd Membranrezeptor (DE-588)4136267-6 gnd Pathobiochemie (DE-588)4044888-5 gnd |
| subject_GND | (DE-588)4429989-8 (DE-588)4136267-6 (DE-588)4044888-5 (DE-588)4143413-4 |
| title | Chemokines, chemokine receptors, and disease |
| title_auth | Chemokines, chemokine receptors, and disease |
| title_exact_search | Chemokines, chemokine receptors, and disease |
| title_full | Chemokines, chemokine receptors, and disease ed. by Lisa M. Schwiebert |
| title_fullStr | Chemokines, chemokine receptors, and disease ed. by Lisa M. Schwiebert |
| title_full_unstemmed | Chemokines, chemokine receptors, and disease ed. by Lisa M. Schwiebert |
| title_short | Chemokines, chemokine receptors, and disease |
| title_sort | chemokines chemokine receptors and disease |
| topic | Chemokines gtt Chimiokines Chimiokines - Physiopathologie Chimiokines - Récepteurs Ziekten gtt Chemokines Chemokines Pathophysiology Chemokines Receptors Chemokines physiology Receptors, Chemokine physiology Signal Transduction physiology Chemokine (DE-588)4429989-8 gnd Membranrezeptor (DE-588)4136267-6 gnd Pathobiochemie (DE-588)4044888-5 gnd |
| topic_facet | Chemokines Chimiokines Chimiokines - Physiopathologie Chimiokines - Récepteurs Ziekten Chemokines Pathophysiology Chemokines Receptors Chemokines physiology Receptors, Chemokine physiology Signal Transduction physiology Chemokine Membranrezeptor Pathobiochemie Aufsatzsammlung |
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