Vitamin C as biomarker and treatment of oxidative stress caused by smoking: methodological and clinical studies
Gespeichert in:
| 1. Verfasser: | |
|---|---|
| Format: | Buch |
| Sprache: | German |
| Veröffentlicht: |
Kopenhagen
2005
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| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | Kopenhagen, Univ., Diss., 2005 |
| Beschreibung: | 59 S. graph. Darst. |
| ISBN: | 8776110834 |
Internformat
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Datensatz im Suchindex
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|---|---|
| adam_text | Contents
Preface 5
1. Introduction 9
1.1 Vitamin C as antioxidant 10
1.2 Vitamin C and smoking 10
2. Aims and hypotheses 13
3. Methodology of vitamin C analysis 14
3.1 Assay principles and concerns 14
3.1.1 Ascorbic acid oxidation 15
3.1.2 Dehydroascorbic acid hydrolysis 16
3.1.3 Other issues 17
3.2 Ascorbic acid analysis 17
3.3 Dehydroascorbic acid analysis 19
3.4 Anticipated results 21
3.5 Ascorbate recycling 21
3.5.1 Ascorbate recycling: what is measured? 23
3.5.2 Susceptibility to oxidative challenges 23
4. Effects of smoking on vitamin C homeostasis 26
4.1 Vitamin C as biomarker of oxidative stress (Hypothesis A) 26
4.1.1 Effects of smoking, gender and age 26
4.1.2 Steady state concentration of dehydroascorbic acid in nonsmokers ..27
4.1.3 Effects of smoking on plasma dehydroascorbic acid 28
4.2 Vitamin C and smoking (Hypothesis B) 29
4.2.1 Vitamin C and smoking: Effect of smoking cessation 30
4.2.2 Vitamin C and smoking: Effect of smoking per se 31
4.2.3 Vitamin C and smoking: Effect of pharmacokinetics 32
4.3 Recycling of ascorbic acid (Hypothesis C) 33
4.3.1 Recycling of ascorbic acid: Effect of oxidative stress in guinea pigs 34
4.3.2 Recycling of ascorbic acid: Effect of smoking 36
4.3.3 Recycling of ascorbic acid: Effect of vitamin C depletion 38
5. Effects of antioxidant intervention in smokers 40
5.1 Determination of an DRI of vitamin C for smokers 40
5.2 Vitamin C supplementation in smokers (Hypothesis D) 42
5.2.1 Vitamin C supplementation in poorly nourished smokers 42
5.2.2 Vitamin C supplementation in smokers: Effect of dosage 43
5.3 Antioxidant intervention in smokers: Effect on oxidative damage 44
6. Summary and conclusions 46
7. Summary in Danish Dansk resume 48
References 50
Abbreviations 59
7
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| indexdate | 2024-07-09T20:06:02Z |
| institution | BVB |
| isbn | 8776110834 |
| language | German |
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| spelling | Lykkesfeldt, Jens Verfasser aut Vitamin C as biomarker and treatment of oxidative stress caused by smoking methodological and clinical studies by Jens Lykkesfeldt Kopenhagen 2005 59 S. graph. Darst. txt rdacontent n rdamedia nc rdacarrier Kopenhagen, Univ., Diss., 2005 Oxidatieve stress gtt Roken gtt Vitamine C gtt Vitamin C Vitamin C Therapeutic use Vitamin C (DE-588)4063638-0 gnd rswk-swf (DE-588)4113937-9 Hochschulschrift gnd-content Vitamin C (DE-588)4063638-0 s DE-604 HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=013109917&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Lykkesfeldt, Jens Vitamin C as biomarker and treatment of oxidative stress caused by smoking methodological and clinical studies Oxidatieve stress gtt Roken gtt Vitamine C gtt Vitamin C Vitamin C Therapeutic use Vitamin C (DE-588)4063638-0 gnd |
| subject_GND | (DE-588)4063638-0 (DE-588)4113937-9 |
| title | Vitamin C as biomarker and treatment of oxidative stress caused by smoking methodological and clinical studies |
| title_auth | Vitamin C as biomarker and treatment of oxidative stress caused by smoking methodological and clinical studies |
| title_exact_search | Vitamin C as biomarker and treatment of oxidative stress caused by smoking methodological and clinical studies |
| title_full | Vitamin C as biomarker and treatment of oxidative stress caused by smoking methodological and clinical studies by Jens Lykkesfeldt |
| title_fullStr | Vitamin C as biomarker and treatment of oxidative stress caused by smoking methodological and clinical studies by Jens Lykkesfeldt |
| title_full_unstemmed | Vitamin C as biomarker and treatment of oxidative stress caused by smoking methodological and clinical studies by Jens Lykkesfeldt |
| title_short | Vitamin C as biomarker and treatment of oxidative stress caused by smoking |
| title_sort | vitamin c as biomarker and treatment of oxidative stress caused by smoking methodological and clinical studies |
| title_sub | methodological and clinical studies |
| topic | Oxidatieve stress gtt Roken gtt Vitamine C gtt Vitamin C Vitamin C Therapeutic use Vitamin C (DE-588)4063638-0 gnd |
| topic_facet | Oxidatieve stress Roken Vitamine C Vitamin C Vitamin C Therapeutic use Hochschulschrift |
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