Genetics of populations:
Gespeichert in:
| 1. Verfasser: | |
|---|---|
| Format: | Buch |
| Sprache: | English |
| Veröffentlicht: |
Sudbury, Mass. [u.a.]
Jones and Bartlett
2005
|
| Ausgabe: | 3. ed. |
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | XIII, 737 S. Ill., zahlr. graph. Darst. |
| ISBN: | 0763747726 |
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Datensatz im Suchindex
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| adam_text | GENETICS OF POPULATIONS THIRD EDITION PHILIP W. HEDRICK ARIZONA STATE
UNIVERSITY UNIVERSITSTS- UR.D LANDES- BIBLIOTHEK DARMSTADT BIBLIOTHOK
BIOIOGIE JONES AND BARTLETT PUBLISHERS SUDBURY, MASSACHUSETTS BOSTON
TORONTO LONDON SINGAPORE BRIEF CONTENTS PREFACE XIII CHAPTER 1. GENERAL
BACKGROUND AND THE DIVERSITY OF GENETIC VARIATION CHAPTER 2. MEASURES OF
GENETIC VARIATION 61 CHAPTER 3. SELECTION: AN INTRODUCTION 113 CHAPTER
4. SELECTION: ADVANCED TOPICS 173 CHAPTER 5. INBREEDING 237 CHAPTER 6.
GENETIC DRIFT AND EFFECTIVE POPULATION SIZE 299 CHAPTER 7. MUTATION 357
CHAPTER 8. NEUTRAL THEORY AND COALESCENCE 407 CHAPTER 9. GENE FLOW AND
POPULATION STRUCTURE 469 CHAPTER 10. LINKAGE DISEQUILIBRIUM AND
RECOMBINATION 525 CHAPTER 11. MOLECULAR POPULATION GENETICS AND
EVOLUTION 597 BIBLIOGRAPHY 664 ANSWERS TO NUMERICAL PROBLEMS 721 INDEX
725 CONTENTS PREFACE CHAPTER 1. GENERAL BACKGROUND AND THE DIVERSITY OF
GENETIC VARIATION 1 I. APPROACHES TO POPULATION GENETICS 2 II.
INTRODUCTION TO SOME GENETIC TOPICS 6 A. SOME GENETIC TERMS 6 B. THE
GENETIC CODE 10 C. STRUCTURE OF THE GENOME AND A TYPICAL EUKARYOTIC GENE
11 III. INTRODUCTION TO SOME QUANTITATIVE TOPICS 14 A. MODELS 14 B.
MEANS, VARIANCES, AND CONFIDENCE INTERVALS 17 C. PROBABILITY 22 D.
MATRICES 26 IV. GENETIC VARIATION 27 A. ALLOZYME VARIATION 31 B.
NUCLEOTIDE AND AMINO ACID SEQUENCE VARIATION 35 C. VISIBLE POLYMORPHISMS
43 D. MUTANTS, LETHALS, AND FITNESS MODIFIERS 45 E. POLYGENIC OR
QUANTITATIVE TRAITS 53 II. DIFFERENT FREQUENCIES BETWEEN THE SEXES 72 A.
AUTOSOMAL GENES 72 B. X-LINKED GENES OR GENES IN HAPLO-DIPLOID ORGANISMS
75 III. ESTIMATES OF ALLELE FREQUENCY 79 IV. TESTING HARDY*WEINBERG
PROPORTIONS 90 V. MEASURES OF GENETIC VARIATION 97 A. HETEROZYGOSITY 97
B. OTHER MEASURES 102 . VI. MEASURES OF NUCLEOTIDE AND AMINO ACID
DIVERSITY 104 VII. MEASURES OF GENETIC DISTANCE 106 CHAPTER 3.
SELECTION: AN INTRODUCTION 113 CHAPTER 2. MEASURES OF GENETIC VARIATION
61 II. I. THE HARDY-WEINBERG PRINCIPLE A. TWO ALLELES 64 B. MULTIPLE
ALLELES 70 63 THE BASIC SELECTION MODEL 119 A. RECESSIVE LETHAL 123 B.
SELECTION AGAINST RECESSIVES C. INTERMEDIATE DOMINANCE (ADDITIYITY) 130
D. SELECTION AGAINST DOMINANTS E. GENERAL DOMINANCE 135 F. HETEROZYGOTE
ADVANTAGE (OVERDOMINANCE) 139 G. HETEROZYGOTE DISADVANTAGE
(UNDERDOMINANCE) 144 ESTIMATION OF SELECTION 147 A. VIABILITY SELECTION
147 B. GENOTYPE FREQUENCIES AND SOME CAVEATS 150 C. DEVIATIONS FROM
MENDELIAN EXPECTATIONS 152 127 134 VIII CONTENTS D. RELATIVE RISK 155
III. RELAXING SOME GENETIC ASSUMPTIONS 157 A. MULTIPLE ALLELES 158 B.
X-LINKED GENES OR GENES IN HAPLO-DIPLOID ORGANISMS 164 CHAPTER 4.
SELECTION: ADVANCED TOPICS 173 I. VIABILITY SELECTION 176 A. VIABILITY
DIFFERENCES IN DIFFERENT LIFE STAGES 176 B. VIABILITY DIFFERENCES IN THE
SEXES 177 C. MATERNAL-FETAL INTERACTIONS 180 D. ANTAGONISTIC PLEIOTROPY
184 II. SEXUAL SELECTION 188 A. NEGATIVE-ASSORTATIVE MATING 190 B.
RARE-MALE MATING ADVANTAGE 192 C. FEMALE CHOICE, MHC, AND NEGATIVE
ASSORTATIVE MATING 195 III. GAMETIC SELECTION 196 A. MEIOTIC DRIVE OR
SEGREGATION DISTORTION 197 B. SELF-INCOMPATIBILITY ALLELES 200 IV.
ECOLOGICAL GENETICS AND BALANCING SELECTION 204 A. SPATIAL VARIATION 210
B. TEMPORAL VARIATION 215 C. FREQUENCY-DEPENDENT SELECTION 221 D.
HOST-PATHOGEN INTERACTIONS 228 CHAPTER 5. INBREEDING 237 I. INBREEDING
238 A. SELF-FERTILIZATION 245 B., PARTIAL SELF-FERTILIZATION 249 C.
ESTIMATES OF OUTCROSSING, SELF-FERTILIZATION, AND BIPARENTAL INBREEDING
252 D. REGULAR SYSTEMS OF INBREEDING 259 E. OTHER LEVELS OF PARTIAL
INBREEDING 262 F. ESTIMATION OF INBREEDING FROM PEDIGREES 264 G. THE
CHAIN-COUNTING TECHNIQUE 266 H. RELATEDNESS 271 .I. KIN SELECTION 278
II. INBREEDING AND SELECTION 279 A. INBREEDING DEPRESSION 279 B. CHANGE
IN ALLELE FREQUENCY AND CONDITIONS FOR A POLYMORPHISM 286 III.
POSITIVE-ASSORTATIVE MATING 292 CHAPTER 6. GENETIC DRIFT AND EFFECTIVE
POPULATION SIZE 299 I. THE EFFECT OF GENETIC DRIFT 304 A. THE
PROBABILITY MATRIX APPROACH 310 II. EFFECTIVE POPULATION SIZE 318 A.
SEPARATE SEXES 320 B. VARIATION IN NUMBER OF GAMETES 324 C. VARIATION IN
TIME 329 D. OTHER FACTORS THAT MAY INFLUENCE EFFECTIVE POPULATION SIZE
334 E. GENETIC TECHNIQUES FOR ESTIMATING EFFECTIVE POPULATION SIZE 336
F. THE FOUNDER EFFECT AND BOTTLENECKS 342 III. SELECTION IN FINITE
POPULATIONS 349 A. DIRECTIONAL SELECTION 349 B. BALANCING SELECTION 353
CHAPTER 7. MUTATION 357 I. ALLELE FREQUENCY CHANGE CAUSED BY MUTATION
362 A. FORWARD AND BACKWARD MUTATION 364 B. THE FATE OF A SINGLE
MUTATION 366 II. MUTATION-SELECTION BALANCE 368 A. RECESSIVE MUTANTS 368
B. OTHER LEVELS OF DOMINANCE AND MUTATION LOAD 372 III. MUTATION IN A
FINITE POPULATION 376 A. NEUTRALITY 376 B. SELECTION 385 IV. ESTIMATION
OF MUTATION RATES 390 A. DOMINANT OR CODOMINANT MUTANTS 391 B. RECESSIVE
MUTANTS 395 CONTENTS IX C. MUTATION ACCUMULATION ESTIMATES 396 D.
FACTORS INFLUENCING THE MUTATION RATE 400 CHAPTER 8. NEUTRAL THEORY AND
COALESCENCE 407 I. NEUTRAL THEORY AND PREDICTIONS ABOUT MOLECULAR
VARIATION 408 A. BALANCING SELECTION 408 B. THE NEUTRAL THEORY 411 C.
THE MOLECULAR CLOCK 416 II. TESTS OF THE NEUTRAL THEORY AND EVIDENCE OF
SELECTION 428 A. EWENS-WATTERSON TEST 429 B. TAJIMATEST 433 C.
HUDSON-KREITMAN-AGUADE (HKA) TEST 436 D. MCDONALD-KREITMAN (MK) TEST 440
E. SYNONYMOUS AND NONSYNONYMOUS NUCLEOTIDE SUBSTITUTIONS 443 F. CODON
USAGE 449 III. COALESCENCE AND GENE GENEALOGIES 452 A. AN INTRODUCTION
TO COALESCENCE 452 B. ESTIMATING EFFECTIVE POPULATION SIZE 462 CHAPTER
9. GENE FLOW AND POPULATION STRUCTURE 469 I. POPULATION STRUCTURE 471 A.
THE CONTINENT-ISLAND MODEL 472 B. GENERAL MODEL 476 C. WAHLUND S
PRINCIPLE 479 D. GAMETIC AND ZYGOTIC GENE , FLOW 482 II. ESTIMATION OF
GENE FLOW AND POPULATION STRUCTURE 483 A. HYBRID POPULATIONS 484 B. F
COEFFICIENTS AND OTHER DIFFERENTIATION MEASURES 488 C. SEX DIFFERENCES
IN GENE FLOW 495 III. POPULATION STRUCTURE AND GENETIC DRIFT 499 A. THE
CONTINENT-ISLAND OR ISLAND MODEL 500 B. THE STEPPING-STONE MODEL AND
ISOLATION BY DISTANCE 504 C. METAPOPULATION 507 , IV. GENE FLOW AND
SELECTION 509 A. THE CONTINENT-ISLAND MODEL 510 B. VARIABLE SELECTION
AND CLINES IN A SUBSTRUCTURED POPULATION 517 CHAPTER 10. LINKAGE
DISEQUILIBRIUM AND RECOMBINATION 525 I. LINKAGE DISEQUILIBRIUM 527 A.
THE LINKAGE DISEQUILIBRIUM MEASURE, D 528 B. OTHER MEASURES OF LINKAGE
DISEQUILIBRIUM 532 C. RATE OF RECOMBINATION, C 537 II. THE INFLUENCE OF
GENETIC DRIFT, MUTATION, INBREEDING, AND GENE FLOW IN LINKAGE
DISEQUILIBRIUM 541 A. GENETIC DRIFT 541 B. MUTATION 545 C. INBREEDING
548 D. GENE FLOW 551 III. MULTILOCUS SELECTION 554 A. FITNESS EPISTASIS
555 B. DIRECTIONAL SELECTION AT TWO LOCI 557 C. GENERAL TWO-LOCUS
POLYMORPHISMS 559 D. SELECTION AT MORE THAN TWO LOCI 566 IV. GENETIC
BACKGROUND, GENETIC HITCHHIKING, AND RELATED TOPICS 567 A. GENETIC
BACKGROUND 568 B. GENETIC HITCHHIKING 571 C. SELECTIVE SWEEPS AND
BACKGROUND SELECTION 576 D. AGE OF A FAVORABLE AGE 580 E. ADVANTAGES AND
DISADVANTAGES OF RECOMBINATION (SEX) 583 V. ESTIMATION OF LINKAGE
DISEQUILIBRIUM 585 A. DIRECT IDENTIFICATION OF GAMETES 586 B. TWO
CODOMINANT LOCI 589 C. EXTENSION TO MULTIPLE ALLELES 591 CONTENTS
CHAPTER 11. MOLECULAR POPULATION GENETICS AND EVOLUTION 597 I. MOLECULAR
PHYLOGENETICS 598 A. UNWEIGHTED PAIR GROUP METHOD (UPGMA) 601 . B.
NEIGHBOR-JOINING (NJ) METHOD 605 C. MAXIMUM PARSIMONY 609 D.
PHYLOGEOGRAPHY 611 II. PATERNITY ANALYSIS AND INDIVIDUAL IDENTITY 621 A.
PATERNITY EXCLUSION 622 B. PATERNITY ASSIGNMENT 630 C. INDIVIDUAL
IDENTITY 636 . D. POPULATION ASSIGNMENT 646 III. IDENTIFYING GENES
INFLUENCING QUANTITATIVE TRAITS 650 A. IDENTIFYING QTLS BY CROSSES 652
B. HAPLOTYPE MAPPING 658 BIBLIOGRAPHY 664 ANSWERS TO NUMERICAL PROBLEMS
INDEX 725 721
|
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| spelling | Hedrick, Philip W. Verfasser aut Genetics of populations Philip W. Hedrick 3. ed. Sudbury, Mass. [u.a.] Jones and Bartlett 2005 XIII, 737 S. Ill., zahlr. graph. Darst. txt rdacontent n rdamedia nc rdacarrier Populationsgenetik (DE-588)4046804-5 gnd rswk-swf Populationsgenetik (DE-588)4046804-5 s DE-604 HEBIS Datenaustausch Darmstadt application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=012968965&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Hedrick, Philip W. Genetics of populations Populationsgenetik (DE-588)4046804-5 gnd |
| subject_GND | (DE-588)4046804-5 |
| title | Genetics of populations |
| title_auth | Genetics of populations |
| title_exact_search | Genetics of populations |
| title_full | Genetics of populations Philip W. Hedrick |
| title_fullStr | Genetics of populations Philip W. Hedrick |
| title_full_unstemmed | Genetics of populations Philip W. Hedrick |
| title_short | Genetics of populations |
| title_sort | genetics of populations |
| topic | Populationsgenetik (DE-588)4046804-5 gnd |
| topic_facet | Populationsgenetik |
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