Cell and molecular biology: concepts and experiments
Gespeichert in:
| 1. Verfasser: | |
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| Format: | Buch |
| Sprache: | English |
| Veröffentlicht: |
New York [u.a.]
Wiley
2005
|
| Ausgabe: | 4. ed., internat. ed. |
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | Getr. Zählung Ill., graph. Darst. Web site password |
| ISBN: | 0471656658 0471465801 |
Internformat
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| 100 | 1 | |a Karp, Gerald |e Verfasser |4 aut | |
| 245 | 1 | 0 | |a Cell and molecular biology |b concepts and experiments |c Gerald Karp |
| 250 | |a 4. ed., internat. ed. | ||
| 264 | 1 | |a New York [u.a.] |b Wiley |c 2005 | |
| 300 | |a Getr. Zählung |b Ill., graph. Darst. |e Web site password | ||
| 336 | |b txt |2 rdacontent | ||
| 337 | |b n |2 rdamedia | ||
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Datensatz im Suchindex
| _version_ | 1804132816764534784 |
|---|---|
| adam_text | Brief Table of Contents 1 Introduction to the Study of Cell Biology 1
I, The f hpmiral Bask of I iff 32
J Bioenergetics, En7ymes, and Metabolism 86
T The Structure and Funrtion of the Plasma Membrane 121
j Aerobir Respiration and the Mitochondrion 182
O Photosynthesis and the Chloroplast 217
/ Interactions Between Tells and Their Environment 243
O fytoplasmic Membrane Systems; Structure, Function, and Membrane Trafficking 279
9 The Cytoskeleton and fell Motility 334
10 The Nature of the Gene and the Genome 396
1 1 Expression of Genetic Information; From Transcription to Translation 436
12 The Cell Nucleus and the Control of Gene Expression 492
JL J DNA Replication and Repair 550
14 Cellular Reproduction 578
1 5 Cell Signaling and Signal Transduction; Communication Between Cells 624
16 Cancel 669
1 7 The Immune Response 700
10 Techniques in Cell and Molecular Biology 733
Glossary G l
Index 1 1
xvii
Contents I Intrnriiirtlontnth* Study «if fall Blnlngy 1
1.1 The Discovery of Cells 2
1.2 Basic Properties of Cells 3
Cells are Highly Complex and Organized 3
Cells Possess a Genetic Program
and the Means to Use It 5
Cells Are Capable of Producing More
ofThemselves 5
Cells Acquire and Utilize Energy 5
Cells Carry Out a Variety
of Chemical Reactions 6
Cells Engage in Numerous
Mechanical Activities 6
Cells Are Able to Respond to Stimuli 6
Cells Are Capable to Self Regulation 6
1.3 Two Fundamentally Different
Classes of Cells 7
Characteristics That Distinguish Prokaryotic
and Eukaryotic Cells 9
Types of Prokaryotic Cells 13
Types of Eukaryotic Cells:
Cell Specialization 15
¦ THE HUMAN PERSPECTIVE: THE PROSPECT
FOR CELL REPLACEMENT THERAPY 18
The Sizes of Cells and Their Components 20
1.4 Viruses 21
Viroids 24
¦ EXPERIMENTAL PATHWAYS:
THE ORIGIN OF EUKARYOTIC CELLS 25
Z Thp fhpmiral Ragfo of I Ifa 3a
2.1 Covalent Bonds 33
Polar and Nonpolar Molecules 34
Ionization 34
¦ THE HUMAN PERSPECTIVE: FREE RADICALS
AS A CAUSE OF AGING 35
xviii
2.2 Noncovalent Bonds 36
Ionic Bonds: Attractions
Between Charged Atoms 36
Hydrogen Bonds 36
Hydrophobic Interactions
and van der Waals Forces 37
The Life Supporting Properties of Water 38
2.3 Acids, Bases, and Buffers 39
2.4 The Nature of Biological Molecules 41
Functional Groups 42
A Classification of Biological Molecules
by Function 42
2.5 Four Types of Biological Molecules 43
Carbohydrates 43
Lipids 48
Proteins 51
¦ THE HUMAN PERSPECTIVE:
PROTEIN FOLDING CAN HAVE
DEADLY CONSEQUENCES 66
Nucleic Acids 75
2.6 The Formation of Complex
Macromolecular Structures 78
The Assembly of Tobacco Mosaic Virus
Particles and Ribosomal Subunits 78
¦ EXPERIMENTAL PATHWAYS: CHAPERONES:
HELPING PROTEINS REACH THEIR PROPER
FOLDED STATE 79
J RlnfttifnyoHrs, FnwnmiB, anH Mat»hrtlt em 86
3.1 Bioenergetics 87
The Laws of Thermodynamics
and the Concept of Entropy 87
Free Energy 89
3.2 Enzymes as Biological Catalysts 95
The Properties of Enzymes 95
Overcoming the Activation Energy Barrier 96
The Active Site and Molecular Specificity 98
Mechanisms of Enzyme Catalysis 99
Enzyme Kinetics 103
¦ THE HUMAN PERSPECTIVE: THE GROWING
PROBLEM OF ANTIBIOTIC RESISTANCE 106
3.3 Metabolism 108
An Overview of Metabolism 108
Oxidation and Reduction:
A Matter of Electrons 109
The Capture and Utilization of Energy 110
Metabolic Regulation 115
T* The Structure of Function
of the Plasma Membrane 121
4.1 An Overview of Membrane Functions 122
4.2 A Brief History of Studies
on Plasma Membrane Structure 123
4.3 The Chemical Composition
of Membranes 126
Membrane Lipids 126
Membrane Carbohydrates 130
4.4 The Structures and Functions
of Membrane Proteins 131
Integral Membrane Proteins 132
Studying the Structure and Properties
of Integral Membrane Proteins 133
Peripheral Membrane Proteins 136
Lipid Anchored Membrane Proteins 137
4.5 Membrane Lipids
and Membrane Fluidity 138
The Importance of Membrane Fluidity 139
Maintaining Membrane Fluidity 139
The Asymmetry of Membrane Lipids 139
Lipid Rafts 140
4.6 The Dynamic Nature
of the Plasma Membrane 141
The Diffusion of Membrane Proteins
after Cell Fusion 141
Restrictions on Protein and Lipid Mobility 144
The Red Blood Cell: An Example
of Plasma Membrane Structure 146
4.7 The Movement of Substances
Across Cell Membranes 149
The Energetics of Solute Movement 149
Diffusion of Substances
through Membranes 150
Facilitated Diffusion 158
Active Transport 158
Contents xix
¦ THE HUMAN PERSPECTIVE: DEFECTS
IN ION CHANNELS AS A CAUSE
OF INHERITED DISEASE 162
4.8 Membrane Potentials
and Nerve Impulses 166
The Resting Potential 166
The Action Potential 167
Propagation of Action Potentials
as an Impulse 169
Neurotransmission: Jumping
the Synaptic Cleft 170
¦ EXPERIMENTAL PATHWAYS:
THE ACETYLCHOUNE RECEPTOR 173
D Aerobic Respiration
and the Mitochondrion 182
5.1 Mitochondrial Structure and Function 183
Mitochondrial Membranes 185
The Mitochondrial Matrix 185
5.2 Oxidative Metabolism
in the Mitochondrion 186
The Tricarboxylic Acid (TCA) Cycle 189
The Importance of Reduced Coenzymes
in the Formation of ATP 190
¦ THE HUMAN PERSPECTIVE: THE ROLE
OF ANAEROBIC AND AEROBIC METABOLISM
IN EXERCISE 191
5.3 The Role of Mitochondria
in the Formation of ATP 193
Oxidation Reduction Potentials 193
Electron Transport 194
Types of Electron Carriers 195
5.4 Translocation of Protons and the
Establishment of a Proton motive Force 201
5.5 The Machinery for ATP Formation 203
The Structure of ATP Synthase 203
The Basis of ATP Formation According
to the Binding Change Mechanism 206
Other Roles for the Proton motive Force
in Addition to ATP Synthesis 210
5.6 Peroxisomes 211
¦ THE HUMAN PERSPECTIVE: DISEASES THAT
RESULT FROM ABNORMAL MITOCHRONDRIAL
OR PEROXISOMAL FUNCTION 212
O Photosynthesis and the Chlnrnplast 217
6.1 Chloroplast Structure and Function 219
6.2 An Overview
of Photosynthetic Metabolism 220
xx Contents
6.3 The Absorption of Light 222
Photosynthetic Pigments 222
6.4 Photosynthetic Units
and Reaction Centers 224
Oxygen Formation: Coordinating the Action
of Two Different Photosynthetic Systems 225
Killing Weeds
by Inhibiting Electron Transport 231
6.5 Photophosphorylation 231
Noncyclic Versus Cyclic
Photophosphorylation 232
6.6 Carbon Dioxide Fixation
and the Synthesis of Carbohydrate 232
Carbohydrate Synthesis in C3 Plants 233
Carbohydrate Synthesis in C4 Plants 237
Carbohydrate Synthesis in CAM Plants 239
I Interactions Between Cells
and Thftlr Environment 243
7.1 The Extracellular Space 244
The Extracellular Matrix 244
7.2 I nteractions of Cells
with Extracellular Materials 252
Integrins 252
Focal Adhesions and Hemidesmosomes:
Anchoring Cells to Their Substratum 256
7.3 Interactions of Cells with Other Cells 258
Selectins 258
Immunoglobulins and Integrins 259
Cadherins 261
¦ THE HUMAN PERSPECTIVE: THE ROLE
OF CELL ADHESION IN INFLAMMATION
AND METASTASIS 263
Adherens Junctions and Desmosomes:
Anchoring Cells to Other Cells 264
The Role of Cell Adhesion Receptors
in Transmembrane Signaling 266
7.4 Tight Junctions: Sealing
the Extracellular Space 268
7.5 Gap Junctions and Plasmodesmata:
Mediating Intercellular Communication 270
Plasmodesmata 273
7.6 Cell Walls 273
O Cytoplasmic Membrane Systems: Structure,
Function, and Membrane Trafficking 279
8.1 An Overview
of the Endomembrane System 280
8.2 A Few Approaches to the Study
of Endomembranes 282
Insights Gained from Autoradiography 283
Insights Gained from the Use
of the Green Fluorescent Protein 283
Insights Gained from the Biochemical Analysis
of Subcellular Fractions 284
Insights Gained from the Use
of Cell Free Systems 285
Insights Gained from the Study
of Genetic Mutants 286
8.3 The Endoplasmic Reticulum 287
The Smooth Endoplasmic Reticulum 289
Functions of the Rough Endoplasmic
Reticulum 290
From the ER to the Golgi Complex:
The First Step in Vesicular Transport 298
8.4 The Golgi Complex 299
Glycosylation in the Golgi Complex 301
The Movement of Materials
Through the Golgi Complex 302
8.5 Types of Vesicle Transport
and Their Functions 304
COPII Coated Vesicles: Transporting Cargo
from the ER to the Golgi Complex 305
COPI Coated Vesicles: Transporting Escaped
Proteins Back to the ER 306
Beyond the Golgi Complex:
Sorting Proteins at the TGN 307
Targeting Vesicles
to a Particular Compartment 308
8.6 Lysosomes 3
¦ THE HUMAN PERSPECTIVE:
DISORDERS RESULTING FROM DEFECTS
IN LYSOSOMAL FUNCTION 313
8.7 Plant Cell Vacuoles 3*5
Endocytosis 316
8.8 The Endocytic Pathway: Moving Membrane
and Materials into the Cell Interior 3*6
Phagocytosis 322
8.9 Posttranslational Uptake of Proteins
by Peroxisomes, Mitochondria,
and Chloroplasts 323
Uptake of Proteins into Peroxisomes 324
Uptake of Proteins into Mitochondrial 324
Uptake of Proteins into Chloroplasts 325
¦ EXPERIMENTAL PATHWAYS:
RECEPTOR MEDIATED ENDOCYTOSIS 326
~7 The Cytoskeleton and Cell Mntilify 334
9.1 Overview of the Major Functions
oftheCytoskeleton 335
9.2 The Study of the Cytoskeleton 337
The Use of Fluorescence Microscopy 337
The Use of Video Microscopy and Laser
Beams for In Vitro Motility Assays 338
The Use of Cells with Altered
Gene Expression 338
9.3 Microtubules 341
Structure and Composition 341
Microtubule Associated Proteins 341
Microtubules as Structural Supports
and Organizers 341
Microtubules as Agents
of Intracellular Motility 343
Motor Proteins That Traverse
the Microtubular Cytoskeleton 344
Microtubule Organizing Centers
(MTOCs) 348
The Dynamic Properties
ofMicrotubules 352
¦ THE HUMAN PERSPECTIVE: THE ROLE
OF CILIA IN DEVELOPMENT AND DISEASE 356
Cilia and Flagella: Structure
and Function 356
The Structure of Cilia and Flagella 358
9.4 Intermediate Filaments 364
Intermediate Filament Assembly
and Disassembly 365
Types and Functions
of Intermediate Filaments 366
9.5 Microfilaments 367
Microfilament Assembly and Disassembly 369
Myosin: The Molecular Motor
for Actin Filaments 370
9.6 Muscle Contractility 375
The Sliding Filament Model
of Muscle Contraction 375
9.7 Nonmuscle Motility 381
Actin Binding Proteins 381
Examples of Nonmuscle Motility
and Contractility 384
10 The Nature of the Gene
10.1 The Concept of a Gene
as a Unit of Inheritance 397
Contents xxi
10.2 Chromosomes:
The Physical Carriers of the Genes 398
The Discovery of Chromosomes 398
Chromosomes as the Carriers
of Genetic Information 399
Genetic Analysis in Drosophila 400
Crossing Over and Recombination 400
Mutagenesis and Giant Chromosomes 402
10.3 The Chemical Nature of the Gene 403
The Structure of DNA 403
The Watson Crick Proposal 404
10.4 The Structure of the Genome 410
The Complexity of the Genome 410
¦ THE HUMAN PERSPECTIVE: DISEASES
THAT RESULT FROM EXPANSION OF
TRINUCLEOTIDE REPEATS 415
10.5 The Stability of the Genome 418
Whole Genome Duplication
(Polyploidization) 418
Duplication and Modification
of DNA Sequences 418
Jumping Genes and the Dynamic Nature
of the Genome 420
10.6 Sequencing Genomes:
The Genetic Basis of Being Human 424
Comparative Genomics: If It s Conserved,
It Must Be Important 425
¦ THE HUMAN PERSPECTIVE: APPLICATION
OF GENOMIC ANALYSES TO MEDICINE 427
¦ EXPERIMENTAL PATHWAYS:
THE CHEMICAL NATURE OF THE GENE 428
1 1 Expression of Genetic Material:
Frnm Transcription to Translation 436
11.1 The Relationship Between Genes
and Proteins 437
An Overview of the Flow of Information
Through the Cell 438
11.2 An Overview of Transcription in Both
Prokaryotic and Eukaryotic Cells 439
Transcription in Prokaryotes 442
Transcription and RNA Processing
in Eukaryotic Cells 443
11.3 Synthesis and Processing
of Ribosomal and Transfer RNAs 444
Synthesizing the rRNA Precursor 445
Processing the rRNA Precursor 447
Synthesis and Processing of the 5S rRNA 450
Transfer RNAs 450
xxii Contents
11.4 Synthesis and Processing
of Messenger RNAs 451
The Machinery for mRNA Transcription 452
Split Genes: An Unexpected Finding 454
The Processing
of Eukaryotic Messenger RNAs 458
Evolutionary Implications of Split Genes
and RNA Splicing 464
Creating New Ribozymes
in the Laboratory 466
11.5 Small Noncoding RNAs
and RNA Interference 467
MicroRNAs: Hundreds of RNAs
of Unknown Function 468
¦ THE HUMAN PERSPECTIVE:
POTENTIAL CLINICAL APPLICATIONS
OF RNA INTERFERENCE 469
11.6 Encoding Genetic Information 470
The Properties of the Genetic Code 470
11.7 Decoding the Codons: The Role
of Transfer RNAs 473
The Structure of tRNAs 473
11.8 Translating Genetic Information 476
Initiation 476
Elongation 479
Termination 481
mRNA Surveillance:
No Nonsense Allowed 482
¦ EXPERIMENTAL PATHWAYS:
THE ROLE OF RNA AS A CATALYST 484
12 The Cell Nucleus and
tht fftntfpl irfpoiMt F»pr«Ht«inn 402
12.1 The Nucleus of a Eukaryotic Cell 493
The Nuclear Envelope 493
Chromosomes and Chromatin 498
¦ THE HUMAN PERSPECTIVE:
CHROMOSOMAL ABERRATIONS 509
Epigenetics: There s More
to Inheritance than DNA Sequence 514
The Nucleus as an Organized Organelle 514
12.2 Control of Gene Expression
in Prokaryotes 517
The Bacterial Operon 517
12.3 Control of Gene Expression
in Eukaryotes 520
12.4 Transcriptional Level Control 522
The Role of Transcription Factors
in Regulating Gene Expression 525
The Structure of Transcription Factors 526
DNA Sites Involved
in Regulating Transcription 529
Transcriptional Activation: The Role
of Enhancers, Promoters, and Coactivators 532
Transcriptional Repression 534
12.5 Processing Level Control 538
12.6 Translational Level Control 539
Cytoplasmic Localization of mRNAs 539
The Control of mRNA Translation 540
The Control of mRNA Stability 542
12.7 Postranslational Control:
Determining Protein Stability 544
X J DNA Replication anr* Repair 550
13.1 DNA Replication 551
Semiconservative Replication 551
Replication in Bacterial Cells 554
The Structure and Functions
of DNA Polymerases 561
Replication in Eukaryotic Cells 564
13.2 DNA Repair 57°
Nucleotide Excision Repair 571
Base Excision Repair 571
Mismatch Repair 572
Double Strand Breakage Repair 573
¦ THE HUMAN PERSPECTIVE:
THE CONSEQUENCES
OF DNA REPAIR DEFICIENCIES 573
13.3 Between Replication and Repair 575
I *y Cellular BaproHnrtinfi 578
14.1 The Cell Cycle 579
Cell Cycles in Vivo 580
Control of the Cell Cycle 580
14.2 M Phase: Mitosis and Cytokinesis 588
Prophase 588
Prometaphase 595
Metaphase 596
Anaphase 598
Telophase 602
Forces Required for Mitotic Movements 602
Cytokinesis 603
14.3 Meiosis 607
The Stages of Meiosis 608
¦ THE HUMAN PERSPECTIVE:
MEIOTIC NONDISJUNCTION
AND ITS CONSEQUENCES 612
Genetic Recombination During Meiosis 615
¦ EXPERIMENTAL PATHWAYS:
THE DISCOVERY AND CHARACTERIZATION
OFMPF 616
1J Cell Signaling and Signal Transduction:
f nmmiiniratinn Bptw«u»n Cells 624
15.1 The Basic Elements
of Cell Signaling Systems 625
15.2 A Survey of Extracellular Messengers
and Their Receptors 626
15.3 G Protein Coupled Receptors
and Their Second Messengers 627
Signal Transduction
by G Protein Coupled Receptors 627
¦ THE HUMAN PERSPECTIVE: DISORDERS
ASSOCIATED WITH G PROTEIN COUPLED
RECEPTORS 631
The Discovery of a Second Messenger:
Cyclic AMP 632
Lipid Derived Second Messengers 633
The Specificity
of G Protein Coupled Responses 636
Regulation of Blood Glucose Levels 637
The Role of GPCRs in Sensory Perception 640
15.4 Protein Tyrosine Phosphorylation
as a Mechanism for Signal Transduction 641
The Ras MAP Kinase Pathway 646
Signaling by the Insulin Receptor 648
Signaling Pathways in Plants 652
15.5 The Role of Calcium
as an Intracellular Messenger 652
Regulating Calcium Concentrations
in Plant Cells 655
15.6 Convergence, Divergence, and Crosstalk
Among Different Signaling Pathways 656
Examples of Convergence, Divergence,
and Crosstalk Among Signaling Pathways 657
15.7 The Role of NO
as an Intercellular Messenger 658
15.8 Apoptosis (Programmed Cell Death) 660
The Extensive Pathway of Apoptosis 661
The Intrinsic Pathway of Apoptosis 662
lOxancei 669
16.1 Basic Properties of a Cancer Cell 670
16.2 The Causes of Cancer 672
16.3 The Genetics of Cancer 673
Tumor Suppressor Genes and Oncogenes:
Brakes and Accelerators 677
Contents xxiii
16.4 New Strategies for Combating Cancer 689
Immunotherapy 690
Gene Therapy 691
Inhibiting the Activity
of Cancer Promoting Proteins 691
Inhibiting the Formation
of New Blood Vessels (Angiogenesis) 692
¦ EXPERIMENTAL PATHWAYS:
THE DISCOVERY OF ONCOGENES 693
X { The Immiinp Rpspnnsg 700
17.1 An Overview of the Immune Response 701
Innate Immune Responses 701
Adaptive Immune Responses 703
17.2 The Clonal Selection Theory
as It Applies to B Cells 704
Vaccination 706
17.3 T Lymphocytes: Activation
and Mechanism of Action 707
17.4 Selected Topics on the Cellular
and Molecular Basis of Immunity 709
The Molecular Structure of Antibodies 709
DNA Rearrangement of Genes Encoding
B and T Cell Antigen Receptors 712
Membrane Bound Antigen Receptor
Complexes 715
The Major Histocompatibility Complex 715
Distinguishing Self from Nonself 720
Lymphocytes Are Activated
by Cell Surface Signals 721
Signal Transduction Pathways Used
in Lymphocyte Activation 723
¦ THE HUMAN PERSPECTIVE:
AUTOIMMUNE DISEASES 724
¦ EXPERIMENTAL PATHWAYS: THE ROLE
OF THE MAJOR HISTOCOMPATIBILITY
COMPLEX IN ANTIGEN PRESENTATION 726
18 Techniques in Cell
and Mnlprntar Rinlngy 733
18.1 The Light Microscope 734
Resolution 734
Visibility 735
Phase Contrast Microscopy 736
Fluorescence Microscopy (and Related
Fluorescence Based Techniques) 737
Video Microscopy and Image Processing 739
Confocal Scanning Light Microscopy 739
Preparation of Specimens
for Light Microscopy 740
xxiv Contents
18.2 Transmission Electron Microscopy 740
Specimen Preparation
for Electron Microscopy 742
18.3 Scanning Electron Microscopy 746
18.4 The Use of Radioisotopes 747
18.5 Cell Culture 749
18.6 The Fractionation of a Cell s Contents
by Differential Centrifugation 751
18.7 Isolation, Purification,
and Fractionation of Proteins 751
Selective Precipitation 752
Liquid Column Chromatography 752
Polyacrylamide Gel Electrophoresis 755
18.8 Determination of Protein Structure 757
18.9 Purification and Fractionation
of Nucleic Acids 758
Separation of DNAs
by Gel Electrophoresis 759
18.10 Measurement of Protein
and Nucleic Acid Concentration 760
18.11 Ultracentrifugation 760
Sedimentation Behavior
of Nucleic Acids 760
18.12 Nucleic Acid Hybridization 761
18.13 RecombinantDNA Technology 763
Restriction Endonucleases 763
Formation of Recombinant DNAs 764
DNA Cloning 765
Chemical Synthesis
and Site Directed Mutagenesis 770
Gene Transfer into Eukaryotic Cells
and Mammalian Embryos 771
Enzymatic Amplification
ofDNAbyPCR 775
DNA Sequencing 777
18.14 The Use of Antibodies 778
|
| any_adam_object | 1 |
| author | Karp, Gerald |
| author_facet | Karp, Gerald |
| author_role | aut |
| author_sort | Karp, Gerald |
| author_variant | g k gk |
| building | Verbundindex |
| bvnumber | BV019375434 |
| callnumber-first | Q - Science |
| callnumber-label | QH581 |
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| callnumber-search | QH581.2 |
| callnumber-sort | QH 3581.2 |
| callnumber-subject | QH - Natural History and Biology |
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| classification_tum | BIO 220f BIO 200f |
| ctrlnum | (OCoLC)475010713 (DE-599)BVBBV019375434 |
| dewey-full | 571.6 |
| dewey-hundreds | 500 - Natural sciences and mathematics |
| dewey-ones | 571 - Physiology & related subjects |
| dewey-raw | 571.6 |
| dewey-search | 571.6 |
| dewey-sort | 3571.6 |
| dewey-tens | 570 - Biology |
| discipline | Biologie |
| edition | 4. ed., internat. ed. |
| format | Book |
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| genre_facet | Lehrbuch |
| id | DE-604.BV019375434 |
| illustrated | Illustrated |
| indexdate | 2024-07-09T19:58:50Z |
| institution | BVB |
| isbn | 0471656658 0471465801 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-012838695 |
| oclc_num | 475010713 |
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| physical | Getr. Zählung Ill., graph. Darst. Web site password |
| publishDate | 2005 |
| publishDateSearch | 2005 |
| publishDateSort | 2005 |
| publisher | Wiley |
| record_format | marc |
| spelling | Karp, Gerald Verfasser aut Cell and molecular biology concepts and experiments Gerald Karp 4. ed., internat. ed. New York [u.a.] Wiley 2005 Getr. Zählung Ill., graph. Darst. Web site password txt rdacontent n rdamedia nc rdacarrier Cytology Molecular biology Cytologie (DE-588)4070177-3 gnd rswk-swf Molekularbiologie (DE-588)4039983-7 gnd rswk-swf Zelle (DE-588)4067537-3 gnd rswk-swf 1\p (DE-588)4123623-3 Lehrbuch gnd-content Zelle (DE-588)4067537-3 s Molekularbiologie (DE-588)4039983-7 s DE-604 Cytologie (DE-588)4070177-3 s HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=012838695&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
| spellingShingle | Karp, Gerald Cell and molecular biology concepts and experiments Cytology Molecular biology Cytologie (DE-588)4070177-3 gnd Molekularbiologie (DE-588)4039983-7 gnd Zelle (DE-588)4067537-3 gnd |
| subject_GND | (DE-588)4070177-3 (DE-588)4039983-7 (DE-588)4067537-3 (DE-588)4123623-3 |
| title | Cell and molecular biology concepts and experiments |
| title_auth | Cell and molecular biology concepts and experiments |
| title_exact_search | Cell and molecular biology concepts and experiments |
| title_full | Cell and molecular biology concepts and experiments Gerald Karp |
| title_fullStr | Cell and molecular biology concepts and experiments Gerald Karp |
| title_full_unstemmed | Cell and molecular biology concepts and experiments Gerald Karp |
| title_short | Cell and molecular biology |
| title_sort | cell and molecular biology concepts and experiments |
| title_sub | concepts and experiments |
| topic | Cytology Molecular biology Cytologie (DE-588)4070177-3 gnd Molekularbiologie (DE-588)4039983-7 gnd Zelle (DE-588)4067537-3 gnd |
| topic_facet | Cytology Molecular biology Cytologie Molekularbiologie Zelle Lehrbuch |
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