Gastroenteropancreatic neuroendocrine tumor disease: molecular and cell biological aspects
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
New York, NY
New York Acad. of Sciences
2004
|
| Schriftenreihe: | Annals of the New York Academy of Sciences
1014 |
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | IX, 302 S. Ill., graph. Darst. |
| ISBN: | 1573314927 1573314935 |
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Datensatz im Suchindex
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| adam_text | ANNALS OF THE NEW YORK ACADEMY OF SCIENCES
Volumel014
April 2004
GASTROENTEROPANCREATIC
NEUROENDOCRINE TUMOR
DISEASE
MOLECULAR AND CELL
BIOLOGICAL ASPECTS
Editors
Bertram Wiedenmann, Gerhard M. Christofori,
Michael Hocker, and Jean Claude Reubi
This volume is the result of a conference entitled 2nd International Conference on Molecular
and Cell Biological Aspects of Gastroenteropancreatic Neuroendocrine Tumor Disease held on
June 19 21, 2003 in Berlin, Germany.
CONTENTS
Preface. By Bertram Wiedenmann ix
Part I. Classification of the Neuroendocrine System
The Normal Endocrine Cell of the Gut: Changing Concepts and New
Evidences. By Guido Rindi, Andrew B. Leiter, Alan S. Kopin,
Cesare Bordi, and Enrico Solcia 1
The Gastroenteropancreatic Neuroendocrine Cell System and Its Tumors:
The WHO Classification. By Gunter Kloppel, Aurel Perren. and
Philipp U. Heitz 13
Part II. Developmental Biology
Transcription Factors in Islet Development and Physiology: Role of PDX 1 in
Beta Cell Function. By Danielle Melloul 28
Transgenic Tagging Defining Pancreatic Pedigrees. By PEDRO LUIS
Herrera Merino 38
Part III. Angiogenesis
EG VEGF: A Novel Mediator of Endocrine Specific Angiogenesis,
Endothelial Phenotype, and Function. By JENNIFER LECOUTER,
Rui Lin, and Napoleone Ferrara 50
Multitasking in Tumor Progression: Signaling Functions of Cell Adhesion
Molecules. By Ugo Cavallaro and Gerhard Christofori 58
Molecular Imaging of Tumor Angiogenesis. By MICHAEL SCHIRNER,
Andreas Menrad, Andrew Stephens, Thomas Frenzel,
Peter Hauff, and Kai Licha 67
Molecular Regulation of Lymphangiogenesis. By PlPSA SAHARINEN AND
Tatiana V. Petrova 76
Part IV. Hormones, Receptors, and Signal Transduction
Regulation of Insulin Secretion: Insights from Engineered (3 cell Lines. By
Shimon Efrat 88
Molecular Mechanisms of Gastrin Dependent Gene Regulation. By
Michael Hocker 97
REST and Peace for the Neuronal Specific Transcriptional Program. By
Victoria V. Lunyak, Gratien G. Prefontaine, and
Michael G. Rosenfeld 110
Molecular Signaling of Somatostatin Receptors. By HICHAM LAHLOU,
Julie Guillermet, Marylis Hortala, Fabienne Vernejoul,
Stephane Pyronnet, Corinne Bousquet, and Christiane Susini . 121
Immunohistochemical Localization of Somatostatin Receptor sst2A in Human
Gut and Lung Tissue: Possible Implications for Physiology and Carcino
genesis. By M. Gugger, B. Waser, A. Kappeler, A. Schonbrunn,
and J.C. Reubi 132
Ca2+ Channel Properties in Neuroendocrine Tumor Cell Cultures Investigated
by Whole Cell Patch Clamp Technique. By Stefan Mergler,
Adriana Drost, Wolf Otto Bechstein, Peter Neuhaus, and
Bertram Wiedenmann 137
Part V. Adhesion Molecules in Neuroendocrine Pathobiology
Regulators of Neurite Outgrowth: Role of Cell Adhesion Molecules. By
Darya Kiryushko, Vladimir Berezin, and Elisabeth Bock 140
Cadherin Switch in Tumor Progression. By Rachel B. Hazan, Rui Qiao,
Rinat Keren, Ines Badano, and Kimita Suyama 155
Part VI. Membrane Trafficking/Secretory Apparatus
Lipid Rafts and Apical Membrane Traffic. By JOACHIM Fullekrug AND
Kai Simons 164
Principles of Exocytosis and Membrane Fusion. By Reinhard Jahn 170
Serotonin Secretion by Human Carcinoid BON Cells. By Viet Samuel Tran,
Anne Marie Marion Audibert, Erdem Karatekin, Sebastien
Huet, SoPfflE Cribier, Koulm Guillaumie, Catherine Chapuis,
Claire Desnos, Francois Darchen, and Jean Pierre Henry 179
Part VII. Genetics of Neuroendocrine Tumors
Molecular Pathology of the MEN1 Gene. By SUNITA K. Agarwal,
A. Lee Burns, Karen E. Sukhodolets, Patricia A. Kennedy,
Victor H. Obungu, Alison B. Hickman, Michael E. Mullendore,
Ira Whitten, Monica C. Skarulis, William F. Simonds,
Carmen Mateo, Judy S. Crabtree, Peter C. Scacheri,
Youngmi Ji, Elizabeth A. Novotny, Lisa Garrett Beal,
Jerrold M. Ward, Steven K. Libutti, H. Richard Alexander,
Aniello Cerrato, Michael J. Parisi, Sonia Santa Anna A,
Brian Oliver, Settara C. Chandrasekharappa,
Francis S. Collins, Allen M. Spiegel, and Stephen J. Marx 189
Molecular Genetics of Gastroenteropancreatic Endocrine Tumors. By
Aurel Perren, Paul Komminoth, and Philipp U. Heitz 199
Cyclin Dl in Human Neuroendocrine Tumorigenesis. By Daniel C. Chung .. 209
Analysis of Molecular Pathways in Neuroendocrine Cancers of the
Gastroenteropancreatic System. By Christian N. Arnold,
Andrea Sosnowski, and Hubert E. Blum 218
Programmed Cell Death Protein 4 (PDCD4) Acts As a Tumor Suppressor in
Neuroendocrine Tumor Cells. By Rudiger Goke, Cornelia Gregel,
Alexandra Goke, Rudolf Arnold, Harald Schmidt, and
Brigitte Lankat Buttgereit 220
Part VIII. Advances in Diagnosis and Therapy
of Neuroendocrine Tumors
Survival and Clinical Outcome of Patients with Neuroendocrine Tumors of the
Gastroenteropancreatic Tract in a German Referral Center. By
Ulrich Frank Pape, Michael Bohmig, Uta Berndt, Nikolaus
Tiling, Bertram Wiedenmann, and Ursula Plockinger 222
Peptide Receptor Radionuclide Therapy. By ERIC P. Krenning,
DlK J. KWEKKEBOOM, ROELF VALKEMA, STANISLAS PAUWELS,
Larry K. Kvols, and Marion De Jong 234
PET in the Diagnosis of Neuroendocrine Tumors. By Anders Sundin,
Barbro Eriksson, Mats Bergstrom, Bengt LAngstrom,
Kjell Oberg, and HAkan Orlefors 246
Somatostatin Receptor Targeting for Tumor Imaging and Therapy. By
Carsten Grotzinger and Bertram Wiedenmann 258
Liver Transplantation for Treatment of Metastatic Neuroendocrine Tumors.
By HAkan Ahlman, Styrbiorn Friman, Christian Cahlin,
Ola Nilsson, Svante Jansson, Bo Wangberg, and
Michael Olausson 265
Heterogeneous Expression of Neuroendocrine Marker Proteins in Human
Undifferentiated Carcinoma of the Colon and Rectum. By Patricia
Grabowski, Julia Schonfelder, Gudrun Ahnert Hilger,
Hans Dieter Foss, Harald Stein, Gerd Berger, Martin Zeitz,
and Hans Scherubl 270
GOT1 Xenografted to Nude Mice: A Unique Model for in Vivo Studies
on SSTR Mediated Radiation Therapy of Carcinoid Tumors.
By Ola Nilsson, Lars Kolby, Peter Bernhardt,
Eva Forssell Aronsson, Viktor Johanson, and HAkan Ahlman . 275
Importance of Vesicle Proteins in the Diagnosis and Treatment of
Neuroendocrine Tumors. By Ola Nilsson, Anne Marie Levin
Jakobsen, Lars Kolby, Peter Bernhardt,
Eva Forssell Aronsson, and HAkan Ahlman 280
Implication of the INK4a/ARF Locus in Gastroenteropancreatic Neuro¬
endocrine Tumorigenesis. By Babette Simon and
NlKOLAUS LUBOMIERSKI 284
Index of Contributors 301
Financial assistance was received from:
• NOVARTIS (SWITZERLAND/GERMANY)
The New York Academy of Sciences believes it has a responsibility to provide an open
forum for discussion of scientific questions. The positions taken by the participants in
the reported conferences are their own and not necessarily those of the Academy. The
Academy has no intent to influence legislation by providing such forums.
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| spelling | Gastroenteropancreatic neuroendocrine tumor disease molecular and cell biological aspects ed. by Bertram Wiedenmann ... New York, NY New York Acad. of Sciences 2004 IX, 302 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Annals of the New York Academy of Sciences 1014 Gastroenteropancreatic neuroendocrine tumor disease Molecular aspects Neuroendocrine tumor disease Maagdarmziekten gtt Neuro-endocriene cellen gtt Pancréas - Tumeurs - Congrès Pancréas rasuqam Système gastro-intestinal rasuqam Tractus gastro-intestinal - Tumeurs - Congrès Tumeur neuroendocrinienne rasuqam Tumeur rasuqam Tumeurs neuroendocriniennes - Congrès Tumoren gtt Gastrointestinal Neoplasms pathology Congresses Gastrointestinal system Tumors Congresses Neuroendocrine Tumors pathology Congresses Neuroendocrine tumors Congresses Pancreas Tumors Congresses Pancreatic Neoplasms pathology Congresses (DE-588)1071861417 Konferenzschrift gnd-content Electronic books Wiedenmann, Bertram Sonstige oth Annals of the New York Academy of Sciences 1014 (DE-604)BV002532608 1014 HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=012831277&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Gastroenteropancreatic neuroendocrine tumor disease molecular and cell biological aspects Annals of the New York Academy of Sciences Gastroenteropancreatic neuroendocrine tumor disease Molecular aspects Neuroendocrine tumor disease Maagdarmziekten gtt Neuro-endocriene cellen gtt Pancréas - Tumeurs - Congrès Pancréas rasuqam Système gastro-intestinal rasuqam Tractus gastro-intestinal - Tumeurs - Congrès Tumeur neuroendocrinienne rasuqam Tumeur rasuqam Tumeurs neuroendocriniennes - Congrès Tumoren gtt Gastrointestinal Neoplasms pathology Congresses Gastrointestinal system Tumors Congresses Neuroendocrine Tumors pathology Congresses Neuroendocrine tumors Congresses Pancreas Tumors Congresses Pancreatic Neoplasms pathology Congresses |
| subject_GND | (DE-588)1071861417 |
| title | Gastroenteropancreatic neuroendocrine tumor disease molecular and cell biological aspects |
| title_auth | Gastroenteropancreatic neuroendocrine tumor disease molecular and cell biological aspects |
| title_exact_search | Gastroenteropancreatic neuroendocrine tumor disease molecular and cell biological aspects |
| title_full | Gastroenteropancreatic neuroendocrine tumor disease molecular and cell biological aspects ed. by Bertram Wiedenmann ... |
| title_fullStr | Gastroenteropancreatic neuroendocrine tumor disease molecular and cell biological aspects ed. by Bertram Wiedenmann ... |
| title_full_unstemmed | Gastroenteropancreatic neuroendocrine tumor disease molecular and cell biological aspects ed. by Bertram Wiedenmann ... |
| title_short | Gastroenteropancreatic neuroendocrine tumor disease |
| title_sort | gastroenteropancreatic neuroendocrine tumor disease molecular and cell biological aspects |
| title_sub | molecular and cell biological aspects |
| topic | Gastroenteropancreatic neuroendocrine tumor disease Molecular aspects Neuroendocrine tumor disease Maagdarmziekten gtt Neuro-endocriene cellen gtt Pancréas - Tumeurs - Congrès Pancréas rasuqam Système gastro-intestinal rasuqam Tractus gastro-intestinal - Tumeurs - Congrès Tumeur neuroendocrinienne rasuqam Tumeur rasuqam Tumeurs neuroendocriniennes - Congrès Tumoren gtt Gastrointestinal Neoplasms pathology Congresses Gastrointestinal system Tumors Congresses Neuroendocrine Tumors pathology Congresses Neuroendocrine tumors Congresses Pancreas Tumors Congresses Pancreatic Neoplasms pathology Congresses |
| topic_facet | Gastroenteropancreatic neuroendocrine tumor disease Molecular aspects Neuroendocrine tumor disease Maagdarmziekten Neuro-endocriene cellen Pancréas - Tumeurs - Congrès Pancréas Système gastro-intestinal Tractus gastro-intestinal - Tumeurs - Congrès Tumeur neuroendocrinienne Tumeur Tumeurs neuroendocriniennes - Congrès Tumoren Gastrointestinal Neoplasms pathology Congresses Gastrointestinal system Tumors Congresses Neuroendocrine Tumors pathology Congresses Neuroendocrine tumors Congresses Pancreas Tumors Congresses Pancreatic Neoplasms pathology Congresses Konferenzschrift Electronic books |
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