The metabolism and molecular physiology of Saccharomyces cerevisiae:
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
Boca Raton [u.a.]
CRC Press
2004
|
| Ausgabe: | 2. ed. |
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | XIV, 459 S. Ill., graph. Darst. |
| ISBN: | 0415299004 |
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Datensatz im Suchindex
| _version_ | 1804132794082787328 |
|---|---|
| adam_text | Eciitioo
The Metabolism and Molecular Physiology of Saccharom yces cereuisiae
Edited by
J- Richard Dickinson
Michael Schweizer
CRC PRESS
Boca Raton London- New York Washington, D C
Contents
List of figures
List of tables
List of contributors
Preface
Xlll
xv
xi
ix
1 Life cycle and morphogenesis
J RICHARD DICKINSON
1 1 Introduction 1
1 2 Life cycle 1
1 3 Cell cycle 3
1 4 Pheromone response and mating 7
1 5 Pseudohyphae and invasive haploidfilaments 9
1 6 Meiosis and sporulation 10
1 7 Stationary phase 13
References 14
2 Mother cell-specific ageing 20
MICHAEL BREITENBACH, PETER LAUN, GINO HEEREN, STEPHIJAROLIM
AND ALENA PICHOVA - _
2 1 Introduction 20
2 2 Model systems for ageing research 20
2 3 Determination of replicative (mother cell-specific) lifespan in yeast 21
2 4 Mother cell specificity - public or private phenomenon? 23
2 5 Statistics of lifespan distributions 23
2 6 Technical considerations: preparation of old cells 24
2 7 The senescent phenotype 25
2 8 Ageing and oxidative stress, respiration and the retrograde response 27
2 9 Ageing and the ras genes 31
2 10 Caloric restriction and nutritional control of ageing 32
2 11 Ageing and accumulation of mutations, ERCs, silencing, telomeres and DMA
metabolism 34
2 12 Genetic screens for ageing mutants 36
vi Contents
2 13 Genomic approaches 37
References 38
3 Carbon metabolism 42
ARTHUR L KRUCKEBERG AND J RICHARD DICKINSON
3 1 Introductory remarks 42
3 2 Transport of carbon compounds into the cell and nutrient sensing 42
3 3 Glycolysis 56
3 4 Gluconeogenesis 63
3 5 Hexose monophosphate pathway 64
3 6 Trehalose and glycogen 64
3 7 Tricarboxylic acid cycle and glyoxylate bypass 66
3 8 Regulation and integration of carbon metabolism with other metabolic and
physiological processes 70
3 9 Metabokmdcs as relevant to carbon metabolism: metabolic modelling 73
References 76
4 Nitrogen metabolism 104
J RICHARD DICKINSON
4 1 Introduction 104
4 2 Ammonia, glutamate and glutamine: the major interface with
carbon metabolism 104
4 3 Control of nitrogen metabolism 105
4 4 Concluding remarks 113
References 113
5 Molecular organization and biogenesis of the cell wall 117
FRANS M -KLIS PIET DE GROOT, STANLEY BRUL AND KLAAS HELLINGWERF
5 1 Introduction 117
5 2 General organization and composition of the cell wall 117
5 3 Methodology for cell wall analysis 119
5 4 The 1,3-fi-glucan network 119
5 5 Biogenesis of 1,6-fi-glucan 120
5 6 The contribution of chitin to the mechanical strength of the lateral walls 121
5 7 Cell wall proteins 123
5 8 Surface display of heterologous proteins 125
5 9 jVonconventional cell surface proteins 125
5 10 Molecular organization of the cell wall 126
5 11 Cell wall assembly 129
5 12 Perspectives 131
References 132
Contents vii
6 Lipids and membranes 140
MICHAEL SCHWEIZER
6 1 Introduction 140
6 2 Uptake, activation and intracellular transport of fatty acids 140
6 3 Synthesis, elongation and desaturation of fatty acids 143
6 4 Fatty acid metabolism in mitochondria and peroxisomes 148
6 5 The roles of phospholipids in yeast physiology and membrane homeostasis 154
6 6 UASIXQ - the common denominator of phospholipid regulation 165
6 7 Phospholipid turnover, remodelling and sigrwlling 167
6 8 Phosphoinositides - key players in signalling and regulation of membrane trafficking 169
6 9 Seel 4 — the connection between phospholipids and the Golgi secretory pathway 173
6 10 Sterols - metabolism, uptake, trafficking and regulation 176
6 11 Oxystemls - their role in lipid metabolism, vesicle transport and cell signalling 188
6 12 Sphingolipids - important for cellular structure and signalling 189
6 13 GPI anchors - their rise to the surface 195
6 14 Lipid rafts - the way in and out 199
6 15 Conclusions 200
References 201
7 Protein trafficking 224
JEREMY D BROWN
7 1 Introduction 224
7 2 Protein targeting and translocation 225
7 3 The general secretory pathway 240
7 4 Specialized transport routes 257
7 5 Summary and concluding remarks 260
References 261
8 Protein-phosphorylation and dephosphorylation 284
MICHAEL J R STARK
8 1 Introduction 284
8 2 Cyclin-dependent protein kinases 288
8 3 Cyclic AA IP-dependent protein kinase 299
8 4 SJvFl protein kinase and glucose repression 304
8 5 The TOR signalling pathway 308
8 6 MAP kinase pathways 312
8 7 Protein phosphatase 1 332
8 8 Protein phosphatase 2A 338
8 9 Sit4p protein phosphatase 340
8 10 PP2B 342
8 11 Concluding remarks 343
References 344
viii Contents
9 Stress responses 376
IAN W DAWES
9 1 Introduction 376
9 2 Heat shock 377
9 3 Oxidative stress 384
9 4 Osmotic stress (hypo- and hyperosmotic stress) and salt stress 402
9 5 Freeze—thaw injury 407
9 6 General regulatory mechanisms 410
9 7 Regulation pathways 412
9 8 Cell division cycle arrest: checkpoints 418
9 9 Overlapping regulatory networks and theJuture 420
References 421
Index 439
|
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| spelling | The metabolism and molecular physiology of Saccharomyces cerevisiae ed. by J. Richard Dickinson ... 2. ed. Boca Raton [u.a.] CRC Press 2004 XIV, 459 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Fungal molecular biology Saccharomyces cerevisiae Metabolism Saccharomyces cerevisiae Physiology Saccharomyces cerevisiae metabolism Saccharomyces cerevisiae physiology Physiologie (DE-588)4045981-0 gnd rswk-swf Saccharomyces cerevisiae (DE-588)4178812-6 gnd rswk-swf Molekularbiologie (DE-588)4039983-7 gnd rswk-swf Stoffwechselphysiologie (DE-588)4183413-6 gnd rswk-swf Physiologe (DE-588)4210087-2 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Saccharomyces cerevisiae (DE-588)4178812-6 s Stoffwechselphysiologie (DE-588)4183413-6 s DE-604 Molekularbiologie (DE-588)4039983-7 s Physiologe (DE-588)4210087-2 s Physiologie (DE-588)4045981-0 s 1\p DE-604 Dickinson, J. Richard Sonstige oth HEBIS Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=012823990&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
| spellingShingle | The metabolism and molecular physiology of Saccharomyces cerevisiae Fungal molecular biology Saccharomyces cerevisiae Metabolism Saccharomyces cerevisiae Physiology Saccharomyces cerevisiae metabolism Saccharomyces cerevisiae physiology Physiologie (DE-588)4045981-0 gnd Saccharomyces cerevisiae (DE-588)4178812-6 gnd Molekularbiologie (DE-588)4039983-7 gnd Stoffwechselphysiologie (DE-588)4183413-6 gnd Physiologe (DE-588)4210087-2 gnd |
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| title | The metabolism and molecular physiology of Saccharomyces cerevisiae |
| title_auth | The metabolism and molecular physiology of Saccharomyces cerevisiae |
| title_exact_search | The metabolism and molecular physiology of Saccharomyces cerevisiae |
| title_full | The metabolism and molecular physiology of Saccharomyces cerevisiae ed. by J. Richard Dickinson ... |
| title_fullStr | The metabolism and molecular physiology of Saccharomyces cerevisiae ed. by J. Richard Dickinson ... |
| title_full_unstemmed | The metabolism and molecular physiology of Saccharomyces cerevisiae ed. by J. Richard Dickinson ... |
| title_short | The metabolism and molecular physiology of Saccharomyces cerevisiae |
| title_sort | the metabolism and molecular physiology of saccharomyces cerevisiae |
| topic | Fungal molecular biology Saccharomyces cerevisiae Metabolism Saccharomyces cerevisiae Physiology Saccharomyces cerevisiae metabolism Saccharomyces cerevisiae physiology Physiologie (DE-588)4045981-0 gnd Saccharomyces cerevisiae (DE-588)4178812-6 gnd Molekularbiologie (DE-588)4039983-7 gnd Stoffwechselphysiologie (DE-588)4183413-6 gnd Physiologe (DE-588)4210087-2 gnd |
| topic_facet | Fungal molecular biology Saccharomyces cerevisiae Metabolism Saccharomyces cerevisiae Physiology Saccharomyces cerevisiae metabolism Saccharomyces cerevisiae physiology Physiologie Saccharomyces cerevisiae Molekularbiologie Stoffwechselphysiologie Physiologe Aufsatzsammlung |
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