Interactions between proteins, sugars and surfactants: dynamic studies on adsorption at interfaces
Gespeichert in:
| 1. Verfasser: | |
|---|---|
| Format: | Buch |
| Sprache: | English German |
| Veröffentlicht: |
Aachen
Shaker
2004
|
| Schriftenreihe: | Berichte aus der Pharmazie
|
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | Zugl.: Erlangen-Nürnberg, Univ., Diss., 2004. - Enth. Zsfassung in engl. und dt. Sprache |
| Beschreibung: | III, 150 S. graph. Darst. |
| ISBN: | 3832225080 |
Internformat
MARC
| LEADER | 00000nam a2200000 c 4500 | ||
|---|---|---|---|
| 001 | BV017903280 | ||
| 003 | DE-604 | ||
| 005 | 20040304 | ||
| 007 | t | ||
| 008 | 040304s2004 d||| m||| 00||| eng d | ||
| 016 | 7 | |a 970373163 |2 DE-101 | |
| 020 | |a 3832225080 |9 3-8322-2508-0 | ||
| 035 | |a (OCoLC)76694546 | ||
| 035 | |a (DE-599)BVBBV017903280 | ||
| 040 | |a DE-604 |b ger |e rakwb | ||
| 041 | 0 | |a eng |a ger | |
| 049 | |a DE-29 |a DE-29T | ||
| 084 | |a 610 |2 sdnb | ||
| 100 | 1 | |a Führling, Christian |e Verfasser |4 aut | |
| 245 | 1 | 0 | |a Interactions between proteins, sugars and surfactants |b dynamic studies on adsorption at interfaces |c Christian Führling |
| 264 | 1 | |a Aachen |b Shaker |c 2004 | |
| 300 | |a III, 150 S. |b graph. Darst. | ||
| 336 | |b txt |2 rdacontent | ||
| 337 | |b n |2 rdamedia | ||
| 338 | |b nc |2 rdacarrier | ||
| 490 | 0 | |a Berichte aus der Pharmazie | |
| 500 | |a Zugl.: Erlangen-Nürnberg, Univ., Diss., 2004. - Enth. Zsfassung in engl. und dt. Sprache | ||
| 650 | 0 | 7 | |a Adsorptionskinetik |0 (DE-588)4122762-1 |2 gnd |9 rswk-swf |
| 650 | 0 | 7 | |a Trehalose |0 (DE-588)4290438-9 |2 gnd |9 rswk-swf |
| 650 | 0 | 7 | |a Zerstäubungstrocknung |0 (DE-588)4190759-0 |2 gnd |9 rswk-swf |
| 650 | 0 | 7 | |a Calcitonin |0 (DE-588)4147166-0 |2 gnd |9 rswk-swf |
| 650 | 0 | 7 | |a Trypsinogen |0 (DE-588)4186360-4 |2 gnd |9 rswk-swf |
| 650 | 0 | 7 | |a Zuckertensid |0 (DE-588)4486434-6 |2 gnd |9 rswk-swf |
| 650 | 0 | 7 | |a Pulverherstellung |0 (DE-588)4228872-1 |2 gnd |9 rswk-swf |
| 650 | 0 | 7 | |a Pharmazeutische Technologie |0 (DE-588)4045699-7 |2 gnd |9 rswk-swf |
| 655 | 7 | |0 (DE-588)4113937-9 |a Hochschulschrift |2 gnd-content | |
| 689 | 0 | 0 | |a Trypsinogen |0 (DE-588)4186360-4 |D s |
| 689 | 0 | 1 | |a Calcitonin |0 (DE-588)4147166-0 |D s |
| 689 | 0 | 2 | |a Zerstäubungstrocknung |0 (DE-588)4190759-0 |D s |
| 689 | 0 | 3 | |a Pulverherstellung |0 (DE-588)4228872-1 |D s |
| 689 | 0 | 4 | |a Pharmazeutische Technologie |0 (DE-588)4045699-7 |D s |
| 689 | 0 | |5 DE-604 | |
| 689 | 1 | 0 | |a Trypsinogen |0 (DE-588)4186360-4 |D s |
| 689 | 1 | 1 | |a Calcitonin |0 (DE-588)4147166-0 |D s |
| 689 | 1 | 2 | |a Zuckertensid |0 (DE-588)4486434-6 |D s |
| 689 | 1 | 3 | |a Trehalose |0 (DE-588)4290438-9 |D s |
| 689 | 1 | 4 | |a Zerstäubungstrocknung |0 (DE-588)4190759-0 |D s |
| 689 | 1 | 5 | |a Adsorptionskinetik |0 (DE-588)4122762-1 |D s |
| 689 | 1 | |5 DE-604 | |
| 856 | 4 | 2 | |m GBV Datenaustausch |q application/pdf |u http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=010738156&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |3 Inhaltsverzeichnis |
| 999 | |a oai:aleph.bib-bvb.de:BVB01-010738156 | ||
Datensatz im Suchindex
| _version_ | 1804130566382026753 |
|---|---|
| adam_text | BERICHTE AUS DER PHARMAZIE CHRISTIAN FIIHRLING INTERACTIONS BETWEEN
PROTEINS, SUGARS AND SURFACTANTS - DYNAMIC STUDIES ON ADSORPTION AT
INTERFACES D 29 (DISS. UNIVERSITAT ERLANGEN-NUMBERG) SHAKER VERLAG
AACHEN 2004 CONTENTS I TABLE OF CONTENTS 1 INTRODUCTION 1 2 STRUCTURE
AND SURFACE ACTIVITY OF PROTEINS 5 2.1 PROTEINSTRUCTURE 5 2.1.1 PRIMARY
PROTEIN STRUCTURE 5 .2 SECONDARY PROTEIN STRUCTURE 6 .3 SUPER -
SECONDARY PROTEIN STRUCTURE 7 .4 TERTIARY PROTEIN STRUCTURE 7 .5
QUATERNARY PROTEIN STRUCTURE 8 .6 COMPLEX PROTEIN STRUCTURES 8 2.2
MOLECULAR PROPERTIES OF SURFACE ACTIVE PROTEINS 9 2.3 ADSORPTION OF
PROTEINS 11 2.4 ADSORPTION OF BINARY MIXTURES 20 2.5 ADSORPTION KINETICS
OF PROTEINS 24 2.5.1 MACROSCOPIC DESCRIPTION 24 2.5.2 MICROSCOPIC
DESCRIPTION 30 3 SPRAY DRYING OF PROTEINS 35 3.1 THE SPRAY DRYING
PROCESS 37 3.1.1 ATOMISATION 37 3.1.2 EVAPORATIVE DRYING 37 3.1.3
SEPARATION OF THE DRIED PRODUCT 39 3.2 CAUSES OF PROTEIN DAMAGE 39 3.3
PREVENTION OF DAMAGE TO PROTEINS 41 3.3.1 SUGARS 41 3.3.2
SURFACTANTS.... 43 3.4 AIMS OF THIS PROJECT 49 4 MATERIALS AND METHODS
51 4.1 MATERIALS 51 4.1.1 MODEL PROTEINS 51 4.1.1.1 TRYPSINOGEN R 51
4.1.1.2 SALMON CALCITONIN 52 4.1.2 EXCIPIENTS 53 CONTENTS 4.2 METHODS 53
4.2.1 MAXIMUM BUBBLE PRESSURE TENSIOMETRY 53 4.2.2 RING TENSIOMETRY 56 5
RESULTS AND DISCUSSION 58 5.1 MEASUREMENT OF DYNAMIC INTERFACIAL TENSION
AT TIMES 1000MS 58 5.1.1 INDIVIDUAL SUBSTANCES 58 5.1.1.1 POLYSORBATE
80 58 5.1.1.2 PLURONIC F 127 63 5.1.1.3 TREHALOSE 66 5.1.1.4 TRYPSINOGEN
67 5.1.1.5 SALMON CALCITONIN 71 5.2 CALCULATION OF TOTAL SURFACE EXCESS
74 5.2.1 POLYSORBATE 80 74 5.2.2 PLURONIC F 127 76 5.2.3 TREHALOSE 77
5.2.4 TRYPSINOGEN 78 5.2.5 SALMON CALCITONIN 80 5.3 EFFECT OF ADDED
TREHALOSE ON DYNAMIC ADSORPTION BEHAVIOUR OF SURFACTANTS AND PROTEINS
(BINARY MIXTURES) 82 5.3.1 TREHALOSE / POLYSORBATE 80 82 5.3.2 TREHALOSE
/ PLURONIC F 127 84 5.3.3 TREHALOSE / TRYPSINOGEN 87 5.3.4 TREHALOSE /
SALMON CALCITONIN 89 5.4 EFFECT OF ADDED SURFACTANTS ON DYNAMIC
ADSORPTION BEHAVIOUR OF PROTEINS (BINARY MIXTURES) 91 5.4.1 TRYPSINOGEN
/ POLYSORBATE 80 91 5.4.2 TRYPSINOGEN / PLURONIC F 127 94 5.4.3 SALMON
CALCITONIN / POLYSORBATE 80 97 5.5 EFFECT OF ADDED TREHALOSE ON DYNAMIC
ADSORPTION BEHAVIOUR OF PROTEIN / SURFACTANT MIXTURES (TERNARY MIXTURES)
99 5.5.1 TRYPSINOGEN / TREHALOSE / POLYSORBATE 80 99 5.5.2 TRYPSINOGEN /
TREHALOSE / PLURONIC F 127 101 5.5.3 SALMON CALCITONIN / TREHALOSE /
POLYSORBATE 80 103 CONTENTS III 5.6 DETERMINATION OF ADSORBED FILM
COMPOSITION AT T= 1 MS-1 S .* 104 5.6.1 BINARY MIXTURES 105 5.6.1.1
TRYPSINOGEN / POLYSORBATE 80 105 5.6.1.2 TRYPSINOGEN / PLURONIC F 127
110 5.6.1.3 SALMON CALCITONIN / POLYSORBATE 80 115 5.6.2 TERNARY
MIXTURES 119 5.6.2.1 TRYPSINOGEN/POLYSORBATE 80/TREHALOSE. 119 5.6.2.2
TRYPSINOGEN / PLURONIC F 127/TREHALOSE 124 5.6.2.3 SALMON CALCITONIN /
POLYSORBATE 80 / TREHALOSE 128 6 CONTUSION 134 7 ZUSAMMENFASSUNG 138 8
REFERENCES 142
|
| any_adam_object | 1 |
| author | Führling, Christian |
| author_facet | Führling, Christian |
| author_role | aut |
| author_sort | Führling, Christian |
| author_variant | c f cf |
| building | Verbundindex |
| bvnumber | BV017903280 |
| ctrlnum | (OCoLC)76694546 (DE-599)BVBBV017903280 |
| discipline | Medizin |
| format | Book |
| fullrecord | <?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>02478nam a2200577 c 4500</leader><controlfield tag="001">BV017903280</controlfield><controlfield tag="003">DE-604</controlfield><controlfield tag="005">20040304 </controlfield><controlfield tag="007">t</controlfield><controlfield tag="008">040304s2004 d||| m||| 00||| eng d</controlfield><datafield tag="016" ind1="7" ind2=" "><subfield code="a">970373163</subfield><subfield code="2">DE-101</subfield></datafield><datafield tag="020" ind1=" " ind2=" "><subfield code="a">3832225080</subfield><subfield code="9">3-8322-2508-0</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(OCoLC)76694546</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-599)BVBBV017903280</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-604</subfield><subfield code="b">ger</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1="0" ind2=" "><subfield code="a">eng</subfield><subfield code="a">ger</subfield></datafield><datafield tag="049" ind1=" " ind2=" "><subfield code="a">DE-29</subfield><subfield code="a">DE-29T</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">610</subfield><subfield code="2">sdnb</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Führling, Christian</subfield><subfield code="e">Verfasser</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Interactions between proteins, sugars and surfactants</subfield><subfield code="b">dynamic studies on adsorption at interfaces</subfield><subfield code="c">Christian Führling</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="a">Aachen</subfield><subfield code="b">Shaker</subfield><subfield code="c">2004</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">III, 150 S.</subfield><subfield code="b">graph. Darst.</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="b">n</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="b">nc</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="490" ind1="0" ind2=" "><subfield code="a">Berichte aus der Pharmazie</subfield></datafield><datafield tag="500" ind1=" " ind2=" "><subfield code="a">Zugl.: Erlangen-Nürnberg, Univ., Diss., 2004. - Enth. Zsfassung in engl. und dt. Sprache</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Adsorptionskinetik</subfield><subfield code="0">(DE-588)4122762-1</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Trehalose</subfield><subfield code="0">(DE-588)4290438-9</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Zerstäubungstrocknung</subfield><subfield code="0">(DE-588)4190759-0</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Calcitonin</subfield><subfield code="0">(DE-588)4147166-0</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Trypsinogen</subfield><subfield code="0">(DE-588)4186360-4</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Zuckertensid</subfield><subfield code="0">(DE-588)4486434-6</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Pulverherstellung</subfield><subfield code="0">(DE-588)4228872-1</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Pharmazeutische Technologie</subfield><subfield code="0">(DE-588)4045699-7</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="655" ind1=" " ind2="7"><subfield code="0">(DE-588)4113937-9</subfield><subfield code="a">Hochschulschrift</subfield><subfield code="2">gnd-content</subfield></datafield><datafield tag="689" ind1="0" ind2="0"><subfield code="a">Trypsinogen</subfield><subfield code="0">(DE-588)4186360-4</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="0" ind2="1"><subfield code="a">Calcitonin</subfield><subfield code="0">(DE-588)4147166-0</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="0" ind2="2"><subfield code="a">Zerstäubungstrocknung</subfield><subfield code="0">(DE-588)4190759-0</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="0" ind2="3"><subfield code="a">Pulverherstellung</subfield><subfield code="0">(DE-588)4228872-1</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="0" ind2="4"><subfield code="a">Pharmazeutische Technologie</subfield><subfield code="0">(DE-588)4045699-7</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="0" ind2=" "><subfield code="5">DE-604</subfield></datafield><datafield tag="689" ind1="1" ind2="0"><subfield code="a">Trypsinogen</subfield><subfield code="0">(DE-588)4186360-4</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="1" ind2="1"><subfield code="a">Calcitonin</subfield><subfield code="0">(DE-588)4147166-0</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="1" ind2="2"><subfield code="a">Zuckertensid</subfield><subfield code="0">(DE-588)4486434-6</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="1" ind2="3"><subfield code="a">Trehalose</subfield><subfield code="0">(DE-588)4290438-9</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="1" ind2="4"><subfield code="a">Zerstäubungstrocknung</subfield><subfield code="0">(DE-588)4190759-0</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="1" ind2="5"><subfield code="a">Adsorptionskinetik</subfield><subfield code="0">(DE-588)4122762-1</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="1" ind2=" "><subfield code="5">DE-604</subfield></datafield><datafield tag="856" ind1="4" ind2="2"><subfield code="m">GBV Datenaustausch</subfield><subfield code="q">application/pdf</subfield><subfield code="u">http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=010738156&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA</subfield><subfield code="3">Inhaltsverzeichnis</subfield></datafield><datafield tag="999" ind1=" " ind2=" "><subfield code="a">oai:aleph.bib-bvb.de:BVB01-010738156</subfield></datafield></record></collection> |
| genre | (DE-588)4113937-9 Hochschulschrift gnd-content |
| genre_facet | Hochschulschrift |
| id | DE-604.BV017903280 |
| illustrated | Illustrated |
| indexdate | 2024-07-09T19:23:04Z |
| institution | BVB |
| isbn | 3832225080 |
| language | English German |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-010738156 |
| oclc_num | 76694546 |
| open_access_boolean | |
| owner | DE-29 DE-29T |
| owner_facet | DE-29 DE-29T |
| physical | III, 150 S. graph. Darst. |
| publishDate | 2004 |
| publishDateSearch | 2004 |
| publishDateSort | 2004 |
| publisher | Shaker |
| record_format | marc |
| series2 | Berichte aus der Pharmazie |
| spelling | Führling, Christian Verfasser aut Interactions between proteins, sugars and surfactants dynamic studies on adsorption at interfaces Christian Führling Aachen Shaker 2004 III, 150 S. graph. Darst. txt rdacontent n rdamedia nc rdacarrier Berichte aus der Pharmazie Zugl.: Erlangen-Nürnberg, Univ., Diss., 2004. - Enth. Zsfassung in engl. und dt. Sprache Adsorptionskinetik (DE-588)4122762-1 gnd rswk-swf Trehalose (DE-588)4290438-9 gnd rswk-swf Zerstäubungstrocknung (DE-588)4190759-0 gnd rswk-swf Calcitonin (DE-588)4147166-0 gnd rswk-swf Trypsinogen (DE-588)4186360-4 gnd rswk-swf Zuckertensid (DE-588)4486434-6 gnd rswk-swf Pulverherstellung (DE-588)4228872-1 gnd rswk-swf Pharmazeutische Technologie (DE-588)4045699-7 gnd rswk-swf (DE-588)4113937-9 Hochschulschrift gnd-content Trypsinogen (DE-588)4186360-4 s Calcitonin (DE-588)4147166-0 s Zerstäubungstrocknung (DE-588)4190759-0 s Pulverherstellung (DE-588)4228872-1 s Pharmazeutische Technologie (DE-588)4045699-7 s DE-604 Zuckertensid (DE-588)4486434-6 s Trehalose (DE-588)4290438-9 s Adsorptionskinetik (DE-588)4122762-1 s GBV Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=010738156&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Führling, Christian Interactions between proteins, sugars and surfactants dynamic studies on adsorption at interfaces Adsorptionskinetik (DE-588)4122762-1 gnd Trehalose (DE-588)4290438-9 gnd Zerstäubungstrocknung (DE-588)4190759-0 gnd Calcitonin (DE-588)4147166-0 gnd Trypsinogen (DE-588)4186360-4 gnd Zuckertensid (DE-588)4486434-6 gnd Pulverherstellung (DE-588)4228872-1 gnd Pharmazeutische Technologie (DE-588)4045699-7 gnd |
| subject_GND | (DE-588)4122762-1 (DE-588)4290438-9 (DE-588)4190759-0 (DE-588)4147166-0 (DE-588)4186360-4 (DE-588)4486434-6 (DE-588)4228872-1 (DE-588)4045699-7 (DE-588)4113937-9 |
| title | Interactions between proteins, sugars and surfactants dynamic studies on adsorption at interfaces |
| title_auth | Interactions between proteins, sugars and surfactants dynamic studies on adsorption at interfaces |
| title_exact_search | Interactions between proteins, sugars and surfactants dynamic studies on adsorption at interfaces |
| title_full | Interactions between proteins, sugars and surfactants dynamic studies on adsorption at interfaces Christian Führling |
| title_fullStr | Interactions between proteins, sugars and surfactants dynamic studies on adsorption at interfaces Christian Führling |
| title_full_unstemmed | Interactions between proteins, sugars and surfactants dynamic studies on adsorption at interfaces Christian Führling |
| title_short | Interactions between proteins, sugars and surfactants |
| title_sort | interactions between proteins sugars and surfactants dynamic studies on adsorption at interfaces |
| title_sub | dynamic studies on adsorption at interfaces |
| topic | Adsorptionskinetik (DE-588)4122762-1 gnd Trehalose (DE-588)4290438-9 gnd Zerstäubungstrocknung (DE-588)4190759-0 gnd Calcitonin (DE-588)4147166-0 gnd Trypsinogen (DE-588)4186360-4 gnd Zuckertensid (DE-588)4486434-6 gnd Pulverherstellung (DE-588)4228872-1 gnd Pharmazeutische Technologie (DE-588)4045699-7 gnd |
| topic_facet | Adsorptionskinetik Trehalose Zerstäubungstrocknung Calcitonin Trypsinogen Zuckertensid Pulverherstellung Pharmazeutische Technologie Hochschulschrift |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=010738156&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| work_keys_str_mv | AT fuhrlingchristian interactionsbetweenproteinssugarsandsurfactantsdynamicstudiesonadsorptionatinterfaces |