From molecules to networks: an introduction to cellular and molecular neuroscience
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
Amsterdam [u.a.]
Elsevier
2004
|
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | XII, 583 S. Ill., graph. Darst. 1 CD-ROM ; 12 cm, 2 Beil. |
| ISBN: | 0121486605 |
Internformat
MARC
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| 245 | 1 | 0 | |a From molecules to networks |b an introduction to cellular and molecular neuroscience |c ed. by John H. Byrne ... |
| 264 | 1 | |a Amsterdam [u.a.] |b Elsevier |c 2004 | |
| 300 | |a XII, 583 S. |b Ill., graph. Darst. |e 1 CD-ROM ; 12 cm, 2 Beil. | ||
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| 650 | 4 | |a Cytology | |
| 650 | 4 | |a Molecular neurobiology | |
| 650 | 4 | |a Nervous System |x cytology | |
| 650 | 4 | |a Neurobiology | |
| 650 | 4 | |a Neurons | |
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Datensatz im Suchindex
| _version_ | 1804130448202268672 |
|---|---|
| adam_text | Full C
Contributors xi
Preface xiii
1. Cellular Components of Nervous Tissue
PATRICK R. HOF, BRUCE D. TRAPP, JEAN DE VELLIS,
LUZ CLAUDIO, AND DAVID R. COLMAN
The Neuron 1
The Neuroglia 13
The Cerebral Vasculature 22
2. Subcellular Organization of the Nervous
System: Organelles and Their Functions
SCOTT BRADY, DAVID R. COLMAN, AND PETER BROPHY
Axons and Dendrites: Unique Structural Components
of Neurons 31
Protein Synthesis in Nervous Tissue 36
The Cytoskeletons of Neurons and Glial Cells 47
Molecular Motors in the Nervous System 55
Building and Maintaining Nervous System Cells 58
3. Brain Energy Metabolism
PIERRE ]. MAGISTRETT1
Energy Metabolism of the Brain as a Whole Organ 67
Tight Coupling of Neuronal Activity, Blood Flow, and
Energy Metabolism 70
Energy Producing and Energy Consuming Processes in
the Brain 73
Brain Energy Metabolism at the Cellular Level 77
Glutamate and Nitrogen Metabolism: A Coordinated
Shuttle Between Astrocytes and Neurons 84
The Astrocyte Neuron Metabolic Unit 87
Contents
4. Electrotonic Properties of Axons
and Dendrites
GORDON M. SHEPHERD
Spread of Steady State Signals 93
Spread of Transient Signals 98
Electrotonic Properties Underlying Propagation in
Axons 100
Electrotonic Spread in Dendrites 102
Dynamic Properties of Passive Electrotonic
Structure 106
Relating Passive to Active Potentials 111
5. Membrane Potential and Action Potential
DAVID A. McCORMICK
The Membrane Potential 116
The Action Potential 121
6. Molecular Properties of Ion Channels
LILY YEH JAN AND YUH NUNG JAN
Families of Ion Channels 141
Channel Gating 144
Ion Permeation 149
Ion Channel Distribution 154
Summary 157
7. Dynamical Properties of Excitable Membranes
DOUGLAS A. BAXTER, CARMEN C. CAN AVIER
AND JOHN H. BYRNE
The Hodgkin Huxley Model 161
A Geometric Analysis of Excitability 179
viii con
8. Release of Neurotransmitters
ROBERT S. ZUCKER, DIMITRI M. KULLMANN, AND
THOMAS L. SCHWARZ
Organization of the Chemical Synapse 197
Excitation—Secretion Coupling 202
The Molecular Mechanisms of the Nerve Terminal 208
Quantal Analysis 221
Short Term Synaptic Plasticity 235
9. Pharmacology and Biochemistry of Synaptic
Transmission: Classic Transmitters
ARIEL Y. DEUTCH AND ROBERT H. ROTH
Diverse Modes of Neuronal Communication 245
Chemical Transmission 246
Classic Neurotransmitters 250
Summary 276
10. Nonclassic Signaling in the Brain
ARIEL Y. DEUTCH AND JAMES L. ROBERTS
Peptide Neurotransmitters 279
Neurotensin as an Example of Peptide
Neurotransmitters 285
Unconventional Transmitters 287
Synaptic Transmitters in Perspective 295
11. Neurotransmitter Receptors
M. NEAL WAXHAM
Ionotropic Receptors 299
G Protein Coupled Receptors 319
12. Intracellular Signaling
HOWARD SCHULMAN
Signaling Through G Protein Linked Receptors 335
Modulation ot Neuronal Function by Protein Kinases
and Phosphatases 353
13. Regulation of Neuronal Gene Expression
and Protein Synthesis
JAMES L. ROBERTS AND JAMES R. LUNDBLAD
Intracellular Signaling Affects Nuclear Gene
Expression 371
JTENTS
Role of cAMP and Ca2+ in the Activation Pathways of
Transcription 380
Summary 388
14. Mathematical Modeling and Analysis of
Inttacellular Signaling Pathways
PAUL D. SMOLEN, DOUGLAS A. BAXTER, AND JOHN H. BYRNE
Methods for Modelling Intracellular Signaling
Pathways 393
General Issues in the Modeling of Biochemical
Systems 408
Specific Modeling Methods 411
Summary 426
15. Cell Cell Communication: An Overview
Emphasizing Gap Junctions
DAVID C. SPRAY, ELIANA SCEMES, RENATO ROZENTAL,
AND ROLF DERMIETZEL
Chemical and Electrical Synapses Differ in Functional
Characteristics 435
Biophysical and Pharmacological Properties of Gap
Junctions in the Nervous System 439
Role of Gap Junctions in Functions of Nervous
Tissue 442
Gap Junction Related Neuropathologies 448
16. Postsynaptic Potentials and
Synaptic Integration
JOHN H. BYRNE
Ionotropic Receptors: Mediators of Fast Excitatory and
Inhibitory Synaptic Potentials 459
Metabotropic Receptors: Mediators of Slow Synaptic
Potentials 472
Integration of Synaptic Potentials 475
17. Information Processing in
Complex Dendrites
GORDON M. SHEPHERD
Strategies for Studying Complex Dendrites 480
Summary: The Dendritic Tree as a Complex Information
Processing System 495
CO]
18. Learning and Memory: Basic Mechanisms
THOMAS H. BROWN, JOHN H. BYRNE, KEVIN S. LABAR,
JOSEPH E. LEDOUX, DERICK H. LINDQUIST, RICHARD R
THOMPSON, AND TIMOTHY J. TEYLER
Long Term Synaptic Potentiation and Depression 499
Paradigms Have Been Developed To Study Associative
and Nonassociative Learning 529
Invertebrate Studies: Key Insights From Aplysia Into Basic
Mechanisms of Learning 531
NTENTS ix
Classical Conditioning in Vertebrates: Discrete Responses
and Fear as Models of Associative Learning 543
How Does a Change in Synaptic Strength Store a
Complex Memory? 560
Summary 562
Index 575
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| physical | XII, 583 S. Ill., graph. Darst. 1 CD-ROM ; 12 cm, 2 Beil. |
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| spelling | From molecules to networks an introduction to cellular and molecular neuroscience ed. by John H. Byrne ... Amsterdam [u.a.] Elsevier 2004 XII, 583 S. Ill., graph. Darst. 1 CD-ROM ; 12 cm, 2 Beil. txt rdacontent n rdamedia nc rdacarrier Cytology Molecular neurobiology Nervous System cytology Neurobiology Neurons Neurologie (DE-588)4041888-1 gnd rswk-swf Molekularbiologie (DE-588)4039983-7 gnd rswk-swf Cytologie (DE-588)4070177-3 gnd rswk-swf Neurobiologie (DE-588)4041871-6 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Neurologie (DE-588)4041888-1 s Molekularbiologie (DE-588)4039983-7 s DE-604 Neurobiologie (DE-588)4041871-6 s Cytologie (DE-588)4070177-3 s DE-188 Byrne, John H. Sonstige oth HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=010653820&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | From molecules to networks an introduction to cellular and molecular neuroscience Cytology Molecular neurobiology Nervous System cytology Neurobiology Neurons Neurologie (DE-588)4041888-1 gnd Molekularbiologie (DE-588)4039983-7 gnd Cytologie (DE-588)4070177-3 gnd Neurobiologie (DE-588)4041871-6 gnd |
| subject_GND | (DE-588)4041888-1 (DE-588)4039983-7 (DE-588)4070177-3 (DE-588)4041871-6 (DE-588)4143413-4 |
| title | From molecules to networks an introduction to cellular and molecular neuroscience |
| title_auth | From molecules to networks an introduction to cellular and molecular neuroscience |
| title_exact_search | From molecules to networks an introduction to cellular and molecular neuroscience |
| title_full | From molecules to networks an introduction to cellular and molecular neuroscience ed. by John H. Byrne ... |
| title_fullStr | From molecules to networks an introduction to cellular and molecular neuroscience ed. by John H. Byrne ... |
| title_full_unstemmed | From molecules to networks an introduction to cellular and molecular neuroscience ed. by John H. Byrne ... |
| title_short | From molecules to networks |
| title_sort | from molecules to networks an introduction to cellular and molecular neuroscience |
| title_sub | an introduction to cellular and molecular neuroscience |
| topic | Cytology Molecular neurobiology Nervous System cytology Neurobiology Neurons Neurologie (DE-588)4041888-1 gnd Molekularbiologie (DE-588)4039983-7 gnd Cytologie (DE-588)4070177-3 gnd Neurobiologie (DE-588)4041871-6 gnd |
| topic_facet | Cytology Molecular neurobiology Nervous System cytology Neurobiology Neurons Neurologie Molekularbiologie Cytologie Neurobiologie Aufsatzsammlung |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=010653820&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
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