Strategies for molecular therapy of Duchenne Muscular Dystrophy:
Gespeichert in:
| 1. Verfasser: | |
|---|---|
| Format: | Buch |
| Sprache: | English |
| Veröffentlicht: |
2003
|
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | München, Univ., Diss., 2003 |
| Beschreibung: | 93 Bl. Ill., graph. Darst. |
Internformat
MARC
| LEADER | 00000nam a2200000 c 4500 | ||
|---|---|---|---|
| 001 | BV017561612 | ||
| 003 | DE-604 | ||
| 007 | t| | ||
| 008 | 031008s2003 xx ad|| m||| 00||| eng d | ||
| 016 | 7 | |a 968968317 |2 DE-101 | |
| 035 | |a (OCoLC)76671107 | ||
| 035 | |a (DE-599)BVBBV017561612 | ||
| 040 | |a DE-604 |b ger |e rakwb | ||
| 041 | 0 | |a eng | |
| 049 | |a DE-19 |a DE-12 | ||
| 100 | 1 | |a Dunant, Patrick |d 1970- |e Verfasser |0 (DE-588)125004443 |4 aut | |
| 245 | 1 | 0 | |a Strategies for molecular therapy of Duchenne Muscular Dystrophy |c von Patrick Dunant |
| 264 | 1 | |c 2003 | |
| 300 | |a 93 Bl. |b Ill., graph. Darst. | ||
| 336 | |b txt |2 rdacontent | ||
| 337 | |b n |2 rdamedia | ||
| 338 | |b nc |2 rdacarrier | ||
| 500 | |a München, Univ., Diss., 2003 | ||
| 655 | 7 | |0 (DE-588)4113937-9 |a Hochschulschrift |2 gnd-content | |
| 856 | 4 | 2 | |m DNB Datenaustausch |q application/pdf |u http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=010570247&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |3 Inhaltsverzeichnis |
| 943 | 1 | |a oai:aleph.bib-bvb.de:BVB01-010570247 | |
Datensatz im Suchindex
| _version_ | 1816445169961009152 |
|---|---|
| adam_text |
TABLE OF CONTENTS
SUMMARY 1
PART I BACKGROUND 3
DUCHENNE MUSCULAR DYSTROPHY 3
DYSTROPHIN 5
THE DYSTROPHIN-ASSOCIATED PROTEIN COMPLEX 6
UTROPHIN 10
FUNCTION OF DYSTROPHIN 11
ANIMAL MODELS OF DMD 13
MOLECULAR THERAPY FOR DMD 14
IMMUNE REACTIONS AGAINST TRANSGENE AND VECTOR 18
PART II MATERIAL AND METHODS 21
GENERATION OF DYSTROPHIN TRANSGENIC MDX MICE 21
DYSTROPHIN IMMUNOBLOTTING 22
HISTOCHEMISTRY AND IMMUNOHISTOCHEMISTRY 22
ISOLATION OF IMMORTALISED MYOGENIC CELL LINES 23
FORCE MEASUREMENTS ON ISOLATED MUSCLES 25
GRIP STRENGTH MEASUREMENTS 27
STATISTICS 28
PART III MUSCLE SPECIFIC GENE EXPRESSION IN MCK 1.35KB 30
MINI-DYSTROPHIN TRANSGENIC MDX MICE
INTRODUCTION 30
RESULTS 34
DISCUSSION 45
PART IV GENTAMICIN INDUCED STOP CODON READ-THROUGH 53
INTRODUCTION 53
RESULTS 57
DISCUSSION 64
PART V APPENDIX 71
REFERENCES 71
ABBREVIATIONS 90
CURRICULUM VITAE 92
ACKNOWLEDGEMENTS 93
BIBLIOGRAFISCHE INFORMATIONEN
HTTP://D-NB.INFO/968968317 |
| any_adam_object | 1 |
| author | Dunant, Patrick 1970- |
| author_GND | (DE-588)125004443 |
| author_facet | Dunant, Patrick 1970- |
| author_role | aut |
| author_sort | Dunant, Patrick 1970- |
| author_variant | p d pd |
| building | Verbundindex |
| bvnumber | BV017561612 |
| ctrlnum | (OCoLC)76671107 (DE-599)BVBBV017561612 |
| format | Book |
| fullrecord | <?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>00000nam a2200000 c 4500</leader><controlfield tag="001">BV017561612</controlfield><controlfield tag="003">DE-604</controlfield><controlfield tag="007">t|</controlfield><controlfield tag="008">031008s2003 xx ad|| m||| 00||| eng d</controlfield><datafield tag="016" ind1="7" ind2=" "><subfield code="a">968968317</subfield><subfield code="2">DE-101</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(OCoLC)76671107</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-599)BVBBV017561612</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-604</subfield><subfield code="b">ger</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1="0" ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="049" ind1=" " ind2=" "><subfield code="a">DE-19</subfield><subfield code="a">DE-12</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Dunant, Patrick</subfield><subfield code="d">1970-</subfield><subfield code="e">Verfasser</subfield><subfield code="0">(DE-588)125004443</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Strategies for molecular therapy of Duchenne Muscular Dystrophy</subfield><subfield code="c">von Patrick Dunant</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2003</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">93 Bl.</subfield><subfield code="b">Ill., graph. Darst.</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="b">n</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="b">nc</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="500" ind1=" " ind2=" "><subfield code="a">München, Univ., Diss., 2003</subfield></datafield><datafield tag="655" ind1=" " ind2="7"><subfield code="0">(DE-588)4113937-9</subfield><subfield code="a">Hochschulschrift</subfield><subfield code="2">gnd-content</subfield></datafield><datafield tag="856" ind1="4" ind2="2"><subfield code="m">DNB Datenaustausch</subfield><subfield code="q">application/pdf</subfield><subfield code="u">http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=010570247&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA</subfield><subfield code="3">Inhaltsverzeichnis</subfield></datafield><datafield tag="943" ind1="1" ind2=" "><subfield code="a">oai:aleph.bib-bvb.de:BVB01-010570247</subfield></datafield></record></collection> |
| genre | (DE-588)4113937-9 Hochschulschrift gnd-content |
| genre_facet | Hochschulschrift |
| id | DE-604.BV017561612 |
| illustrated | Illustrated |
| indexdate | 2024-11-22T17:38:23Z |
| institution | BVB |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-010570247 |
| oclc_num | 76671107 |
| open_access_boolean | |
| owner | DE-19 DE-BY-UBM DE-12 |
| owner_facet | DE-19 DE-BY-UBM DE-12 |
| physical | 93 Bl. Ill., graph. Darst. |
| publishDate | 2003 |
| publishDateSearch | 2003 |
| publishDateSort | 2003 |
| record_format | marc |
| spelling | Dunant, Patrick 1970- Verfasser (DE-588)125004443 aut Strategies for molecular therapy of Duchenne Muscular Dystrophy von Patrick Dunant 2003 93 Bl. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier München, Univ., Diss., 2003 (DE-588)4113937-9 Hochschulschrift gnd-content DNB Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=010570247&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Dunant, Patrick 1970- Strategies for molecular therapy of Duchenne Muscular Dystrophy |
| subject_GND | (DE-588)4113937-9 |
| title | Strategies for molecular therapy of Duchenne Muscular Dystrophy |
| title_auth | Strategies for molecular therapy of Duchenne Muscular Dystrophy |
| title_exact_search | Strategies for molecular therapy of Duchenne Muscular Dystrophy |
| title_full | Strategies for molecular therapy of Duchenne Muscular Dystrophy von Patrick Dunant |
| title_fullStr | Strategies for molecular therapy of Duchenne Muscular Dystrophy von Patrick Dunant |
| title_full_unstemmed | Strategies for molecular therapy of Duchenne Muscular Dystrophy von Patrick Dunant |
| title_short | Strategies for molecular therapy of Duchenne Muscular Dystrophy |
| title_sort | strategies for molecular therapy of duchenne muscular dystrophy |
| topic_facet | Hochschulschrift |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=010570247&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| work_keys_str_mv | AT dunantpatrick strategiesformoleculartherapyofduchennemusculardystrophy |