Retinal degenerations: mechanisms and experimental therapy ; [proceedings of the X International Symposium on Retinal Degeneration, held September 30 - October 5, 2002, in Bürgenstock, Switzerland]
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
New York [u.a.]
Kluwer Acad., Plenum Publ.
2003
|
| Schriftenreihe: | Advances in experimental medicine and biology
533 |
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | XVI, 467 S. Ill., graph. Darst. |
| ISBN: | 0306477815 |
Internformat
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| 245 | 1 | 0 | |a Retinal degenerations |b mechanisms and experimental therapy ; [proceedings of the X International Symposium on Retinal Degeneration, held September 30 - October 5, 2002, in Bürgenstock, Switzerland] |c ed. by Matthew M. LaVail ... |
| 264 | 1 | |a New York [u.a.] |b Kluwer Acad., Plenum Publ. |c 2003 | |
| 300 | |a XVI, 467 S. |b Ill., graph. Darst. | ||
| 336 | |b txt |2 rdacontent | ||
| 337 | |b n |2 rdamedia | ||
| 338 | |b nc |2 rdacarrier | ||
| 490 | 1 | |a Advances in experimental medicine and biology |v 533 | |
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| 999 | |a oai:aleph.bib-bvb.de:BVB01-010510668 | ||
Datensatz im Suchindex
| _version_ | 1804130253934690304 |
|---|---|
| adam_text | CONTENTS
MOLECULAR GENETICS AND CANDIDATE GENES
1.
IDENTIFICATION OF THE RP1 AND RP10 (EVfPDHl) GENES
CAUSING AUTOSOMAL DOMINANT RP
............................................ 1
Stephen P. Daiger, Lori S. Sullivan, Sara J. Bowne,
Avril Kennan,
Peter Humphries, David G. Birch, John R. Heckenlively, and the RP1 Consortium
2.
ON THE ROLE OF IMPDH1 IN RETINAL DEGENERATION
..................... 13
Avril
Kennan, Aileen Aheme, Sara J. Bowne, Stephen P. Daiger, G. Jane Farrar,
Paul F. Kenna, and Pete Humphries
3.
AN INTEGRATED GENETIC APPROACH TO IDENTIFY
CANDIDATE GENES FOR HUMAN CHROMOSOME 6q-
LE4KED RETINAL DISORDERS
............................................................. 19
Pamela S.
Lagali,
Radha Ayyagari, and Paul W. Wong
4.
MOUSE GENETIC APPROACHES TO ACCESS PATHWAYS
IMPORTANT IN RETINAL FUNCTION: A VALUABLE TOOL
FOR THE ASSESSMENT OF NOVEL GENE THERAPIES
................ 29
Patsy M. Nishina and
Jürgen
К.
Naggert
5.
RETINAL DEGENERATIVE DISORDERS IN SOUTHERN AFRICA:
A MOLECULAR GENETIC APPROACH
............................................... 35
R.S.
Råmesar,
L.
Roberts,
G.
Rebello,
R.
Goliath, A. Vorster,
Α.
September,
L.
Ehrenreich,
D. Gama,
and J.
Greenberg
CONTENTS
DIAGNOSTIC, CLINICAL, CYTOPATHOLOGICAL AND
PHYSIOLOGIC ASPECTS OF RETINAL DEGENERATION
6.
COMPARING ROD AND CONE FUNCTION WITH
FUNDUS
AUTOFLUORESCENCE IMAGES IN
RETIMTIS
PIGMENTOSA..............................................................................................
41
Anthony
G. Robson,
Catherine Egan, Graham E. Holder, Alan
С
Bird, and
Fred W. Fitzke
7.
A MODIFIED PROTOCOL FOR THE ASSESSMENT OF VISUAL
FUNCTION
Ш
PATIENTS WITH
RETINITIS PIGMENTOSA.........
49
N.
Lodha,
С.
Α.
Westall,
Μ.
Brent,
M. Abdolell, and E. Héon
8.
PRENATAL
HUMAN OCULAR DEGENERATION OCCURS
Ш
LEBER S CONGENITAL
AMAUROSIS: (LCA
1
and
2)...................... 59
Fernanda B. O. Porto,
Isabelle Perrault,
David Hicks, Jean-Michel
Rozet,
Noëlle
Hanoteau,
Sylvain
Hanein, Josseline Kaplan, and
José A. Sahel
9. LEBER
CONGENITAL
AMAUROSIS
- GENOTYPING
REQUIRED
FOR POSSIBLE INCLUSION IN A CLINICAL TRIAL
....................... 69
Isabelle Perrault, Sylvie
Gerber,
Sylvain
Hanein, Serge Picaud, Jean-Michel
Rozet,
Jean-Louis Dufier, Arnold Munnich,
José
Sahel, and Josseline Kaplan
10.
TREATMENT OF CYSTOH)
MACULAR EDEMA
RELATED TO
RETINITIS PIGMENTOSA
WITH
INTRAVITREAL
TRIAMCINOLONE ACETONIDE:
CASE REPORT
............................ 79
Juliana M. F. Sallum,
Michel
E. Farah,
and
Vinícius S. Saraiva
AGE-RELATED
MACULAR
DEGENERATION
11.
PROTEOMIC APPROACHES TO UNDERSTANDING AGE-
RELATED
MACULAR
DEGENERATION
............................................. 83
Joe G. Hollyfield, Robert G. Salomon, and John W. Crabb
12.
PROGRESSIVE PATHWAYS IN AGE-RELATED
MACULAR
DEGENERATION
........................................................................................ 91
Kimberly A. Howes, Jeanne M. Frederick, Alexander Marks, and Wolfgang Baehr
CONTENTS xi
13.
TISSUE
INHIBITOR
OF
METALLOPROTEINASES-S
AND SORSBY
FUNDUS
DYSTROPHY
............................................................................... 97
Jian
Hua Qi, Quteba Ebrahem, and
Bela Anand-Apte
14.
INVESTIGATIONS
OF
RPE
CELLS OF
CHORIODAL
NEOVASCULAR MEMBRANES
FROM
PATIENTS
WITH
AGE-RELATED
MACULA
DEGENERATION
..................................... 107
Rita Rosenthal and Olaf Strauß
15.
RETINAL AND CHOROEDAL ALTERATIONS FOLLOWING
PHOTODYNAMIC THERAPY
.................................................................. 115
Yusuf K. Durlu
USHER SYNDROME AND RELATED TOPICS
16.
USHER SYNDROME: CORRELATION BETWEEN VISUAL FIELD
SIZE AND MAXIMAL ERG RESPONSE B-WAVE
AMPLITUDE
................................................................................................. 123
Alessandro Iannaccone
17.
THE CELLULAR FUNCTION OF THE USHER GENE PRODUCT
MYOSIN VIIA IS SPECIFIED BY ITS LIGANDS
................................. 133
Uwe Wolfrum
18.
MOUSE MODELS FOR USHER SYNDROME IB
......................................... 143
Concepcion Lillo, Junko Kitamoto, Xinran Liu, Elizabeth Quint, Karen P. Steel,
and David S. Williams
19.
SCREEN FOR USHER SYNDROME IB MUTATIONS
ЕЧ
THE
OVINE MYOSIN VILA GENE
.................................................................... 151
Tania
Slätter,
Sassan
M.
Azarian, Scott Tebbutt, Marion Maw, and
David S. Williams
20.
PHOTORECEPTORINTERSEGMENTAL TRANSPORT AND
RETINAL DEGENERATION: A CONSERVED PATHWAY
COMMON TO MOTTLE AND SENSORY CILIA
.................................. 157
Joseph
С
Besharse, Sheila A. Baker,
Katherine Luby-Phelps,
and
Gregory J.
Pazour
xii CONTENTS
ANIMAL
MODELS
OF RETINAL DEGENERATION
21.
INHERITED RETINAL DYSTROPHY IN
MER
KNOCKOUT MICE
........ 165
Jacque L. Duncan, Haidong Yang, Douglas Vollrath, Douglas Yasumura,
Michael T. Matthes,
Nikolaus Trautmann,
Aimée
V.
Chappelow,
Wei Feng,
H. Shelton
Earp, Glenn
К.
Matsushima,
and Matthew
M. LaVail
22.
MOUSE MODELS OF HUMAN RETINAL DISEASE CAUSED BY
EXPRESSION OF MUTANT RHODOPSE4
............................................ 173
May
Nour
and
Muna
I. Naash
23.
EVALUATION OF INNER RETINAL STRUCTURE IN THE AGED
RCSRAT
........................................................................................................ 181
Sherry Ball, Brett Hanzlicek, Melissa Blum, and
Machelle Pardue -
24.
THE INTACT XENOPUS LAEVIS EYE RUDIMENT: A QUASI-IN
VIVO SYSTEM FOR THE STUDY OF RETINAL
DEVELOPMENT AND DEGENERATIONS
........................................... 189
Monica M.
Jabłoński
25. STREPTOZOTOCIN-ESDUCED
DIABETES
-
A RAT MODEL TO
STUDY INVOLVEMENT OF RETINAL CELL TYPES IN THE
ONSET OF DIABETIC RETINOPATHY
................................................. 197
Elisabeth
Rungger-Brändle
and
André
A. Dosso
MECHANISMS OF RETINAL DEGENERATION
26.
A2E, A FLUOROPHORE OF RPE LIPOFUSCE4: CAN IT CAUSE
RPE DEGENERATION?
............................................................................. 205
Janet R. Sparrow,
Bolin
Cai,
Nate Fishkin, Young Pyo Jang,
Sonja Krane,
Heidi
R.Vollmer,
Jilin Zhou, and
Koji
Nakanishi
27.
BRIGHT LIGHT INDUCES RETINAL DEGENERATION BY A
TRANSDUCIN-INDEPENDENT MECHANISM
.................................... 213
Elliott Brill, Sujatha Patnala,
Janis
Lem,
and Martin Obin
CONTENTS xiü
28.
DOES CONSTITUTIVE PHOSPHORYLATION PROTECT
AGAINST PHOTORECEPTOR DEGENERATION IN
ЯРЕбҐ
MICE?
............................................................................................................. 221
Baerbel Rohrer,
Zsolt Ablonczy,
Sergei Znoiko, Michael Redmond, Jian-Xing Ma,
and Rosalie Crouch
29.
LIGHT-INDUCED PHOTORECEPTOR DAMAGE TRIGGERS
DNA
REPAIR: DIFFERENTIAL FATE OF RODS AND CONES
................. 229
M.
Soledad
Cortina, William
С
Gordon, Walter J. Lukiw, and Nicolas G.
Bazan
30.
MITOCHONDRIAL DELETIONS IN NORMAL AND
DEGENERATING RAT RETINA
.............................................................. 241
Arturo Bravo-Nuevo, Neal
Williams, Scott
Geller,
and Jonathan Stone
31.
QUANTITATIVE PCR ANALYSIS OF FosB mRNA EXPRESSION
„
AFTER SHORT DURATION OXYGEN AND LIGHT STRESS
.......... 249
Scott
F. Geller
and Jonathan Stone
32.
METABOLIC MODULATION OF VISUAL SENSITIVITY
........................ 259
Robert B. Barlow, Bart Farell, and Mukhtar Khan
33.
MITOCHONDRIAL UNCOUPLING PROTEINS: REGULATORS OF
RETINAL CELL DEATH
............................................................................ 269
Colin J. Barnstable, Man Li, Rajini Reddy, and
Tamas
L.
Horváth
34.
ENERGY DEPLETION HYPOTHESIS FOR
RETINITIS
PIGMENTOSA..............................................................................................
277
Marion
S.
Eckmiller
35.
FUNCTIONAL STUDIES OF AIPL1: POTENTIAL ROLE OF AIPL1
IN CELL CYCLE EXIT AND/OR DIFFERENTIATION OF
PHOTORECEPTORS
.................................................................................. 287
Dayna T. Akey, Xuemei Zhu, Michael Dyer,
Amin
Li, Adam Sorensen,
Taeko Fukada-Kamitani, Stephen P. Daiger, Cheryl Craft, Tetsu Kamitani, and
Melanie
M.
Sohocki
36.
PHOTORECEPTOR DEGENERATION
ES
PRO23HIS AND S334TER
TRANSGENIC RATS
................................................................................. 297
Donald Lee, Scott
Geller,
Natalie Walsh,
Krisztina Valter,
Doug Yasumura,
Michael Matthes, Matthew LaVail, and Jonathan Stone
xiv CONTENTS
37.
RETINAL
DEGENERATION
CAUSED BY MUTATIONS IN TULP1
....... 303
Quansheng
Xi,
Gayle J.T. Pauer, Karen A.West, John W. Crabb, and
Stephanie A. Hagstrom
38.
TOWARDS UNDERSTANDING THE FUNCTION OF THE TUBBY
GENE FAMILY IN THE RETINA
............................................................. 309
Sakae Ikeda, Akihiro Ikeda,
Jürgen
К.
Naggert,
and Patsy
M.
Nishina
39.
IDENTIFICATION OF DOWNSTREAM MECHANISMS INVOLVED
IN PEDF S ACTIVITY IN THE RETINA BY LARGE SCALE
GENE EXPRESSION PROFILING
........................................................... 315
Joyce Tombran-Tink,
Nuria
Lara, Arvind Chappa, Amber R. Tink,
Lincoln V. Johnson, and Michelle Staples
40.
THE nob MUTATION DOES NOT PROTECT AGAINST LIGHT-
INDUCED RETINAL DEGENERATION
................................................ 327
Machelle
T. Pardue, Christian Grimm, Andreas
Wenzel,
and Charlotte E.
Remé
BASIC SCIENCE UNDERLYING RETINAL DEGENERATION
41.
THE PHAGOCYTOSIS OF OS IS MEDIATED BY THE PI3-KINASE
LINKED TYROSEVE KBVASE RECEPTOR,
MER,
AND IS
STIMULATED BY GAS6
............................................................................ 331
Michael O. Hall, Brian J. Agnew, Toshka A. Abrams, and Barry L. Burgess
42.
ROLE OF
CtvßS E4TEGRIN
IN REGULATING PHAGOCYTOSIS BY
THE RETINAL PIGMENT EPITHELIUM
............................................. 337
Silvia C.
Finnemann
43.
COMPARATIVE STUDY OF CATHEPSIN
D
AND
S
IN RAT IPE
AND RPE CELLS
......................................................................................... 343
Hiroshi
Tornita,
Eriko
Sugano,
Toshiaki Abe, Asahi Yamashita, and
Makoto Tamai
44.
ISOLATION AND CULTURE OF PRIMARY MOUSE RETINAL
PIGMENTED
EPITHELIAL CELLS
........................................................ 347
Daniel Gibbs and David S. Williams
CONTENTS xv
45. REGULATION
OF
THE VISUAL
CYCLE: RETINOL
DEHYDROGENASE AND RETINOL
FLUORESCENCE
MEASUREMENTS IN VERTEBRATE
RETINA................................... 353
M.
Carter
Cornwall,
Efthymia Tsinal,
Rosalie
К.
Crouch, Barbara Wiggert,
Chunhe Chen, and Yiannis Koutalos
46.
MELATONE*
ENHANCES RETE4OIC
АСШ
INDUCTION OF
CONE
ARRESTIN GENE
EXPRESSION IN
RETTNOBLASTOMA CELLS
.................................................................... 361
Aimin Li, Xuemei Zhu, Bruce Brown, and Cheryl M. Craft
47.
REGULATION OF RETINAL
PHOSPHOINOSITIDE 3-KINASE
ACTIVITY IN PeSa-SUBUNIT KNOCKOUT MICE
............................. 369
Raju
V.S.
Rájala,
Mark E. McClellan, John D. Ash, and Robert E. Anderson
48. PERIPHERIN/ÄÖÄ IN
SKATE RETINA
.. ........................................................ 377
Muna
I. Naash, Xi-Qin Ding,
Chibo
Li, John O Brien, and Muayyad R. Al-Ubaidi
NEUROPROTECTION
AND STEM CELLS
49.
XIAP PROTECTS PHOTORECEPTORS FROM N-METHYL-N-
NITROSOUREA-INDUCED RETINAL DEGENERATION
................. 385
Dino
Pétrin,
Adam Baker, Jennifer Brousseau, Stuart
Coupland,
Peter
Liston,
William W. Hauswirth, Robert G. Korneluk, and Catherine Tsilfidis
50.
NEUROPROTECTTVE EFFECT OF ESTROGEN UPON RETINAL
NEURONS
ЕЧ
VITRO
.................................................................................. 395
Wei
Cao,
Raju
V.S.
Rájala,
Feng Li, Robert E. Anderson, Na Wei,
Charles
E. Soliman,
and James F. McGinnis
51.
TRANSGENIC RD MICE HARBORING
АХОКПЧЕ
GENE BY RPE6S
GENE PROMOTER DOES NOT RESCUE PHOTORECEPTOR
DEGENERATION
........................................................................................ 403
Toshiaki Abe, Yuki Yoshioka, Hiroshi
Tomita, Yoko
Saigo, Tetuso Udono,
Shigeki Shibahara, and Makoto Tamai
52.
MARROW STROMAL CELLS-MSCs: A SPECDZS COMPARISON
......... 407
Anthony Kicic, Adam
С
Shanley, Christine M. Hall, and P. Elizabeth
Rakoczy
xvi CONTENTS
GENE
THERAPY
53.
GENE THERAPY FOR
LEBER
CONGENITAL
AMAUROSIS
.................. 415
Nadine S. Dejneka,
Enrico
M. Surace,
and Jean Bennett
54.
FUNCTIONAL AND
STRUCTURAL EVALUATION
AFTER
AAV.RPE65
GENE TRANSFER IN
THE CANINE MODEL OF
LEBER S CONGENITAL
AMAUROSIS .................................................
423
Kristina Narfström,
Ragnheidur
Bragadóttir,
T.
Michael Redmond,
P. Elizabeth
Rakoczy,
Theo
van Veen, and Anitha Bruun
55.
ASSESSMENT OF rAAV-MEDIATED GENE THERAPY IN THE
Rpeóť
MOUSE
............................................................................................. 431
P. Elizabeth
Rakoczy,
Chooi-May Lai, Meaghan J.T. Yu,
Dru M.
Daniels,
Meliha Brankov, Ben C.
Rae,
Chris W. Stoddart, Nigel L.
Őarnett,
Matthew T. Martin-Iverson, T. Michael Redmond,
Kristina Narfström,
Xiaohuai Zhou, and Ian J. Constable
56.
MULLER
CELL TRANSDUCTION BY AAV2 IN NORMAL AND
DEGENERATIVE RETINAS
...................................................................... 439
Fong-Qi Liang, Enrico Surace,
Nadine S.
Dejneka, Albert M. Maguire, and
Jean Bennett
57.
VIRUS-MEDIATED SECRETION GENE THERAPY
-А
POTENTIAL
TREATMENT FOR OCULAR NEOVASCULARIZATION
................. 447
Yvonne K.Y. Lai, Shiwani Sharma, Chooi-May Lai, Meliha Brankov,
Ian J. Constable, and P. Elizabeth
Rakoczy
ABOUT THE EDITORS
............................................................................................. 455
INDEX
........................................................................................................................... 459
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| oclc_num | 614896907 |
| open_access_boolean | |
| owner | DE-12 DE-355 DE-BY-UBR DE-19 DE-BY-UBM |
| owner_facet | DE-12 DE-355 DE-BY-UBR DE-19 DE-BY-UBM |
| physical | XVI, 467 S. Ill., graph. Darst. |
| publishDate | 2003 |
| publishDateSearch | 2003 |
| publishDateSort | 2003 |
| publisher | Kluwer Acad., Plenum Publ. |
| record_format | marc |
| series | Advances in experimental medicine and biology |
| series2 | Advances in experimental medicine and biology |
| spelling | Retinal degenerations mechanisms and experimental therapy ; [proceedings of the X International Symposium on Retinal Degeneration, held September 30 - October 5, 2002, in Bürgenstock, Switzerland] ed. by Matthew M. LaVail ... New York [u.a.] Kluwer Acad., Plenum Publ. 2003 XVI, 467 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Advances in experimental medicine and biology 533 Netzhautdegeneration (DE-588)4171515-9 gnd rswk-swf (DE-588)1071861417 Konferenzschrift 2002 Bürgenstock gnd-content Netzhautdegeneration (DE-588)4171515-9 s DE-604 LaVail, Matthew M. Sonstige oth Advances in experimental medicine and biology 533 (DE-604)BV000003102 533 Digitalisierung TU Muenchen application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=010510668&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Retinal degenerations mechanisms and experimental therapy ; [proceedings of the X International Symposium on Retinal Degeneration, held September 30 - October 5, 2002, in Bürgenstock, Switzerland] Advances in experimental medicine and biology Netzhautdegeneration (DE-588)4171515-9 gnd |
| subject_GND | (DE-588)4171515-9 (DE-588)1071861417 |
| title | Retinal degenerations mechanisms and experimental therapy ; [proceedings of the X International Symposium on Retinal Degeneration, held September 30 - October 5, 2002, in Bürgenstock, Switzerland] |
| title_auth | Retinal degenerations mechanisms and experimental therapy ; [proceedings of the X International Symposium on Retinal Degeneration, held September 30 - October 5, 2002, in Bürgenstock, Switzerland] |
| title_exact_search | Retinal degenerations mechanisms and experimental therapy ; [proceedings of the X International Symposium on Retinal Degeneration, held September 30 - October 5, 2002, in Bürgenstock, Switzerland] |
| title_full | Retinal degenerations mechanisms and experimental therapy ; [proceedings of the X International Symposium on Retinal Degeneration, held September 30 - October 5, 2002, in Bürgenstock, Switzerland] ed. by Matthew M. LaVail ... |
| title_fullStr | Retinal degenerations mechanisms and experimental therapy ; [proceedings of the X International Symposium on Retinal Degeneration, held September 30 - October 5, 2002, in Bürgenstock, Switzerland] ed. by Matthew M. LaVail ... |
| title_full_unstemmed | Retinal degenerations mechanisms and experimental therapy ; [proceedings of the X International Symposium on Retinal Degeneration, held September 30 - October 5, 2002, in Bürgenstock, Switzerland] ed. by Matthew M. LaVail ... |
| title_short | Retinal degenerations |
| title_sort | retinal degenerations mechanisms and experimental therapy proceedings of the x international symposium on retinal degeneration held september 30 october 5 2002 in burgenstock switzerland |
| title_sub | mechanisms and experimental therapy ; [proceedings of the X International Symposium on Retinal Degeneration, held September 30 - October 5, 2002, in Bürgenstock, Switzerland] |
| topic | Netzhautdegeneration (DE-588)4171515-9 gnd |
| topic_facet | Netzhautdegeneration Konferenzschrift 2002 Bürgenstock |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=010510668&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| volume_link | (DE-604)BV000003102 |
| work_keys_str_mv | AT lavailmatthewm retinaldegenerationsmechanismsandexperimentaltherapyproceedingsofthexinternationalsymposiumonretinaldegenerationheldseptember30october52002inburgenstockswitzerland |